Page last updated: 2024-11-06

prednisolone and Cancer of Prostate

prednisolone has been researched along with Cancer of Prostate in 98 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Research Excerpts

ExcerptRelevanceReference
"We have experienced a patient with tumor fever from hormone-refractory prostate cancer (HRPC) who was treated successfully using docetaxel plus prednisolone therapy."7.73[A case of hormone-refractory prostate cancer (HRPC) with tumor fever responding to docetaxel plus prednisolone therapy]. ( Azuma, K; Hashine, K; Miura, N; Numata, K; Sumiyoshi, Y, 2006)
"Flutamide is an antiandrogen and frequently used for the treatment of prostatic cancer."6.42[Toxic hepatitis and liver failure under therapy with flutamide]. ( Haupt, R; Lübbert, C; Ruf, BR; Wiese, M, 2004)
"The antiemetic effect of prednisolone on nausea/vomiting was investigated in 67 patients with advanced prostatic cancer and a performance status of < or = 2."5.08Antiemetic efficacy of prednisolone: a placebo-controlled trial in patients with advanced prostatic cancer treated with estramustine phosphate. ( Bosson, S; Eriksson, T; Henricsson, A; Josefsson, K; Madsen, M; Palmqvist, E; Schelin, S, 1998)
"We have experienced a patient with tumor fever from hormone-refractory prostate cancer (HRPC) who was treated successfully using docetaxel plus prednisolone therapy."3.73[A case of hormone-refractory prostate cancer (HRPC) with tumor fever responding to docetaxel plus prednisolone therapy]. ( Azuma, K; Hashine, K; Miura, N; Numata, K; Sumiyoshi, Y, 2006)
"Among men with high-risk non-metastatic prostate cancer, combination therapy is associated with significantly higher rates of metastasis-free survival compared with ADT alone."2.82Abiraterone acetate and prednisolone with or without enzalutamide for high-risk non-metastatic prostate cancer: a meta-analysis of primary results from two randomised controlled phase 3 trials of the STAMPEDE platform protocol. ( Alzoueb, M; Amos, CL; Atako, N; Attard, G; Birtle, A; Bowen, J; Brawley, C; Brown, LC; Buckner, M; Chowdhury, S; Clarke, NW; Cook, A; Cross, W; Das, P; de Bono, JS; Dearnaley, DP; Gale, J; Gilbert, D; Gillessen, S; Gilson, C; Gray, E; James, ND; Jones, RJ; Langley, RE; Lydon, A; Malik, Z; Mason, MD; Matheson, D; Millman, R; Murphy, L; O'Sullivan, JM; Parikh, O; Parker, CC; Parmar, MKB; Pedley, I; Pugh, C; Robinson, A; Rush, H; Russell, JM; Srihari, N; Sydes, MR; Syndikus, I; Tanguay, J; Thalmann, G; Thomas, C; Wagstaff, J; Wylie, J; Zarkar, A, 2022)
"Prednisolone monotherapy has been the standard systemic treatment in many patients with androgen- independent prostate cancer and should today be compared to treatment with Taxotere plus prednisolone."2.73A randomized phase II trial comparing weekly taxotere plus prednisolone versus prednisolone alone in androgen-independent prostate cancer. ( Fosså, SD, 2008)
"Hormone-refractory prostate cancer (HRPC) is a rapidly progressive disease which produces considerable morbidity and involves mostly men over 70, often comorbid and with poor tolerance to chemotherapy."2.73Oral vinorelbine as first line chemotherapy in unfit elderly patients with hormone-refractory prostate cancer. ( Adamo, V; Buda, C; Caristi, N; Iorfida, M; Lupo, G; Maisano, R; Scimone, A; Scisca, C, 2008)
"Abiraterone acetate is an orally active acetate salt of the steroidal compound abiraterone with antiandrogen activity."2.48Abiraterone acetate in castration-resistant prostate cancer. ( Cortesi, E; Gazzaniga, P; Iacovelli, R; Palazzo, A; Procopio, G, 2012)
"Abiraterone acetate has recently demonstrated a significant improvement in survival when compared to placebo in patients with docetaxel-treated mCRPC."2.47Role of second-line systemic treatment post-docetaxel in metastatic castrate resistant prostate cancer- current strategies and future directions. ( Alhasso, A; Ansari, A; Ansari, J; Glaholm, J; Hussain, SA; Mahmood, R, 2011)
"Advanced prostate cancer is typically sensitive to androgen-deprivation therapy, but invariably progresses to the castration-resistant state."2.47Novel therapeutic strategies for metastatic prostate cancer in the post-docetaxel setting. ( de Bono, JS; Massard, C; Michels, RM; Sartor, O, 2011)
"Treatment of hormone-refractory prostate cancer is palliative, and surgery and radiotherapy are used for the relief of lower urinary tract symptoms and localized painful bony metastases."2.43The changing pattern of management for hormone-refractory, metastatic prostate cancer. ( Bloomfield, D; James, ND; Luscombe, C, 2006)
"Flutamide is an antiandrogen and frequently used for the treatment of prostatic cancer."2.42[Toxic hepatitis and liver failure under therapy with flutamide]. ( Haupt, R; Lübbert, C; Ruf, BR; Wiese, M, 2004)
"Although prostate cancer is a very common form of malignancy in men, the clinical significance of androgen deprivation therapy (ADT) with abiraterone acetate versus the nonsteroidal antiandrogen bicalutamide has not yet been verified in patients with high-risk metastatic hormone-sensitive prostate cancer (mHSPC)."1.72Abiraterone acetate versus nonsteroidal antiandrogen with androgen deprivation therapy for high-risk metastatic hormone-sensitive prostate cancer. ( Egawa, S; Enei, Y; Fukuokaya, W; Hata, K; Iwamoto, Y; Kimura, T; Matsukawa, A; Miki, J; Miyajima, K; Mori, K; Obayashi, K; Onuma, H; Otsuka, T; Sakanaka, K; Sano, T; Shimomura, T; Suzuki, H; Tsuzuki, S; Yanagisawa, T, 2022)
"The 2022 Swedish prostate cancer guidelines include several new recommendations and some that differ from the European guidelines."1.72The Swedish national guidelines on prostate cancer, part 1: early detection, diagnostics, staging, patient support and primary management of non-metastatic disease. ( Bratt, O; Carlsson, S; Fransson, P; Kindblom, J; Stranne, J; Thellenberg Karlsson, C, 2022)
"Metastatic prostate cancer, Hormone resistant prostate cancer, Weekly docetaxel."1.72Comparison of Weekly Low Dose Docetaxel with the Standard Protocol in Hormone-resistant Metastatic Prostate Cancer. ( Celenkoglu, G; Sayin, M, 2022)
"Prostate cancer is a commonly diagnosed and treated malignancy, although it rarely presents with cutaneous metastases."1.40Cutaneous metastasis of prostate carcinoma treated with radiotherapy: a case presentation. ( Chin, M; De Souza, P; Mak, G; Nahar, N, 2014)
"Abiraterone was well tolerated."1.39Antitumour activity of abiraterone acetate against metastatic castration-resistant prostate cancer progressing after docetaxel and enzalutamide (MDV3100). ( Albiges, L; Attard, G; Bianchini, D; De Bono, JS; Fizazi, K; Ileana, E; Loriot, Y; Massard, C; Patrikidou, A; Pezaro, C; Sandhu, S, 2013)
"Treatment with cabazitaxel plus prednisone has improved overall survival of 2."1.38[Cabazitaxel after docetaxel: a new option in metastatic castration-resistant prostate cancer]. ( Joly, F; Lheureux, S, 2012)
"We describe interstitial pneumonitis induced by bicalutamide prescribed to treat prostate cancer."1.37Interstitial pneumonitis induced by bicalutamide given for prostate cancer. ( Masago, T; Motoda, K; Nemoto, R; Watanabe, T, 2011)
"The objective of this study was to evaluate the efficacy and toxicity of docetaxel in combination with prednisolone in Japanese patients with hormone refractory prostate cancer."1.36Docetaxel in combination with prednisolone for hormone refractory prostate cancer. ( Ide, H; Kikuchi, E; Kono, H; Miyajima, A; Nagata, H; Nakagawa, K; Nakashima, J; Ohigashi, T; Oya, M, 2010)
"Patients with recurrent prostate cancer may be treated with androgen deprivation strategies; however, most patients will develop androgen-independent prostate cancer."1.33Docetaxel-based regimens, the standard of care for metastatic androgen-insensitive prostate cancer. ( Arlen, PM; Gulley, JL, 2005)
"A 88-year-old man with prostate cancer was receiving non-steroidal anti-androgen therapy (flutamide, 375 mg/day)."1.32Interstitial pneumonitis related to flutamide monotherapy for prostate cancer. ( Fujimoto, N; Matsumoto, T; Nomura, M; Sato, H, 2004)
"Biopsy specimen revealed malignant lymphoma."1.28[Triple malignancy including bladder carcinoma, prostate carcinoma and malignant lymphoma: a case report]. ( Kobayashi, Y; Kuyama, J; Matsuda, M; Miyagawa, M; Ohnishi, S; Oritani, K; Tada, Y; Yasunaga, Y; Yoshioka, T, 1989)
"Estramustine has been shown previously to be an effective drug in the treatment of metastatic prostatic cancer, demonstrating significant objective and subjective responses in long-term non-randomized trials and in other randomized trials."1.26The use of estramustine and prednimustine versus prednimustine alone in advanced metastatic prostatic cancer patients who have received prior irradiation. ( Chu, TM; Gaeta, JF; Gibbons, RP; Johnson, DE; Loening, SA; Murphy, GP; Prout, GR; Saroff, J; Schmidt, JD; Scott, WW; Slack, N; Soloway, MS; Wajsman, Z, 1979)
"Estramustine is a combination of estradiol and nitrogen mustard, and alone has shown objective responses in advanced prostatic cancer."1.26Combined therapy of advanced prostatic carcinoma with estramustine and prednimustine. ( Catane, R; Kaufman, J; Mittelman, A; Murphy, GP, 1977)

Research

Studies (98)

TimeframeStudies, this research(%)All Research%
pre-199012 (12.24)18.7374
1990's7 (7.14)18.2507
2000's27 (27.55)29.6817
2010's41 (41.84)24.3611
2020's11 (11.22)2.80

Authors

AuthorsStudies
Kularatne, SA1
Venkatesh, C1
Santhapuram, HK1
Wang, K1
Vaitilingam, B1
Henne, WA1
Low, PS1
Yanagisawa, T1
Kimura, T1
Mori, K1
Suzuki, H2
Sano, T1
Otsuka, T1
Iwamoto, Y1
Fukuokaya, W1
Miyajima, K1
Enei, Y1
Sakanaka, K1
Matsukawa, A1
Onuma, H1
Obayashi, K1
Tsuzuki, S1
Hata, K1
Shimomura, T1
Miki, J1
Egawa, S1
Attard, G7
Murphy, L2
Clarke, NW6
Cross, W3
Jones, RJ6
Parker, CC4
Gillessen, S5
Cook, A3
Brawley, C3
Amos, CL3
Atako, N1
Pugh, C3
Buckner, M1
Chowdhury, S4
Malik, Z3
Russell, JM6
Gilson, C4
Rush, H3
Bowen, J2
Lydon, A1
Pedley, I2
O'Sullivan, JM3
Birtle, A3
Gale, J4
Srihari, N2
Thomas, C3
Tanguay, J2
Wagstaff, J4
Das, P3
Gray, E3
Alzoueb, M1
Parikh, O4
Robinson, A3
Syndikus, I2
Wylie, J4
Zarkar, A3
Thalmann, G1
de Bono, JS6
Dearnaley, DP5
Mason, MD5
Gilbert, D3
Langley, RE3
Millman, R5
Matheson, D4
Sydes, MR6
Brown, LC2
Parmar, MKB6
James, ND7
Grünwald, V1
Ohlmann, CH1
Hadaschik, B1
Ali, A1
Hoyle, AP1
Brawley, CD2
Cross, WR2
Diaz-Montana, C2
Malik, ZI2
Matheson, DJ1
Berthold, DR2
Buckner, ML1
Ritchie, AWS2
Birtle, AJ2
Brock, SJ1
Ford, D1
Grant, W2
Gray, EK1
Hoskin, P1
Khan, MM1
Manetta, C1
McPhail, NJ1
Perna, C1
Pezaro, CJ1
Protheroe, AS1
Robinson, AJ1
Rudman, SM1
Sheehan, DJ1
Srihari, NN2
Tanguay, JS1
Thomas, CW1
Vengalil, S1
Wylie, JP1
Clarke, CS1
Hunter, RM1
Gabrio, A1
Ingleby, FC1
Rush, HL1
Parker, C2
Lester, JF2
Bratt, O1
Carlsson, S1
Fransson, P1
Thellenberg Karlsson, C1
Stranne, J1
Kindblom, J1
Sayin, M1
Celenkoglu, G1
Uemura, H2
Matsumoto, R1
Mizokami, A3
Miyake, H2
Matsuyama, H1
Nakamura, K1
Saito, K1
Kawakita, M1
Takeshita, H1
Koroki, Y1
Ono, S1
Murota, M1
Ito, M1
Kamoto, T1
Fujimoto, K1
Sachdeva, A1
Jones, C1
Hoyle, A1
Abdel-Aty, H1
Murphy, C1
Parkar, N1
Pezaro, C3
Saxby, H1
Alzouebi, M1
Montazeri, AH1
Cathomas, R1
Brown, MD1
Jain, Y1
George, DJ1
Kimura, G1
Fujii, Y1
Hinotsu, S1
Izumi, K1
Ly, LK1
Rowles, JL1
Paul, HM1
Alves, JMP1
Yemm, C1
Wolf, PM1
Devendran, S1
Hudson, ME1
Morris, DJ1
Erdman, JW1
Ridlon, JM1
Yasukawa, H1
Ikehata, Y1
Tsuboi, Y1
Nishiyama, N2
Watanabe, A1
Fujiuchi, Y1
Kitamura, H1
Fizazi, K3
Tran, N1
Fein, L1
Matsubara, N1
Rodriguez-Antolin, A1
Alekseev, BY1
Özgüroğlu, M1
Ye, D1
Feyerabend, S1
Protheroe, A2
De Porre, P1
Kheoh, T1
Park, YC1
Todd, MB1
Chi, KN1
Spears, MR2
Adab, F1
Aung, S1
Brock, S1
Chakraborti, P1
Ferguson, C1
Hingorani, M1
Hoskin, PJ1
McKinna, F1
McPhail, N1
Money-Kyrle, J1
O'Sullivan, J1
Struss, WJ1
Black, PC1
Hahn, AW1
Hale, P1
Rathi, N1
Agarwal, N1
Rulach, RJ1
McKay, S1
Neilson, S1
White, L1
Wallace, J1
Carruthers, R1
Lamb, C1
Cascales, A1
Marashi, H1
Glen, H1
Venugopal, B1
Sadoyze, A1
Sidek, N1
Alhasso, A2
Dodds, D1
Laskey, J1
MacLeod, N1
Vale, CL1
Fisher, DJ1
White, IR1
Carpenter, JR1
Burdett, S1
Gravis, G1
Rydzewska, LH1
Sweeney, CJ1
Tierney, JF1
Spratt, DE1
Loriot, Y1
Bianchini, D1
Ileana, E1
Sandhu, S1
Patrikidou, A1
Albiges, L1
Massard, C2
End, D1
Molina, A1
Todd, M1
Meyers, ML1
Kusukawa, N2
Ishida, H1
Tanase, K1
Ito, H2
Aoki, Y1
Ooyama, N1
Akino, H2
Yokoyama, O2
Inamura, S1
Taga, M1
Tsuchiyama, K1
Oyama, N1
Lee, JL1
Ahn, JH1
Choi, MK1
Kim, Y1
Hong, SW1
Lee, KH1
Jeong, IG1
Song, C1
Hong, BS1
Hong, JH1
Ahn, H1
Mak, G1
Chin, M1
Nahar, N1
De Souza, P1
Moriceau, G1
Guillot, A1
Pacaut, C1
Méry, B1
Falk, AT1
Trone, JC1
Collard, O1
De Laroche, G1
Fournel, P1
Merrouche, Y1
Magné, N1
Ureshino, H1
Miyahara, M1
Fosså, SD4
Caristi, N1
Maisano, R1
Iorfida, M1
Scimone, A1
Lupo, G1
Buda, C1
Scisca, C1
Adamo, V1
Naito, M1
Itoh, K1
Komatsu, N1
Yamashita, Y1
Shirakusa, T1
Yamada, A1
Moriya, F1
Ayatuka, H1
Mohamed, ER1
Matsuoka, K2
Noguchi, M1
Horti, J1
Widmark, A1
Stenzl, A1
Federico, MH1
Abratt, RP1
Sanders, N1
Pover, GM1
Bodrogi, I1
Ide, H1
Kikuchi, E1
Kono, H1
Nagata, H1
Miyajima, A1
Nakagawa, K1
Ohigashi, T1
Nakashima, J1
Oya, M1
Kaprin, AD1
Gafanov, RA1
Al'bitskiĭ, IA1
Fastovets, SV1
Chin, K1
Fujimura, M1
Sekit, N1
Mikami, K1
Kamijima, S1
Ichikawa, T1
Miura, N3
Numata, K3
Kusuhara, Y1
Shirato, A1
Hashine, K4
Sumiyoshi, Y4
Maehana, T1
Mizuno, T1
Muto, M1
Yanase, M1
Ladoire, S1
Eymard, JC1
Zanetta, S1
Mignot, G1
Martin, E1
Kermarrec, I1
Mourey, E1
Michel, F1
Cormier, L1
Ghiringhelli, F1
Kinouchi, T1
Kinoshita, T1
Kobayashi, M2
Ueda, T1
Inoue, H1
Takada, T1
Hara, T1
Yamaguchi, T1
Kamiya, K1
Izumi, N1
Hisanaga, T1
Higashi, K1
Shima, Y1
Hirayama, Y1
Ito, Y1
Kanamaru, T1
Sonoda, T1
Aoyama, M1
Nakamura, N1
Kawamura, M1
Ansari, J1
Hussain, SA1
Mahmood, R1
Ansari, A1
Glaholm, J1
Masago, T1
Watanabe, T2
Nemoto, R1
Motoda, K1
Yanagi, M1
Nishimura, T1
Kurita, S1
Lee, C1
Kondo, Y1
Yamazaki, K1
Sartor, O1
Michels, RM1
Al-Mohizea, AM1
Al-Omar, MA1
Abdalla, MM1
Amr, AG1
Ohmori, S1
Yaguchi, T1
Nakamura, M1
Iacovelli, R1
Palazzo, A1
Procopio, G1
Gazzaniga, P1
Cortesi, E1
Jones, M1
Kobylecki, C1
Marshall, AG1
Silverdale, MA1
Talbot, PR1
Muramaki, M1
Fujisawa, M1
Nishimura, K1
Nonomura, N1
Kanayama, HO1
Ozono, S1
Miura, T1
Miki, T1
Kakehi, Y1
Arai, Y1
Ogawa, O1
Fujita, R1
Nonomura, K1
Hoshi, S2
Akaza, H2
Richards, J1
Lim, AC1
Hay, CW1
Taylor, AE1
Wingate, A1
Nowakowska, K1
Carreira, S1
Goodall, J1
Arlt, W1
McEwan, IJ1
Perry, CJ1
Sundar, S1
Lheureux, S1
Joly, F1
Dyer, M1
Rinaldi, F1
George, E1
Adler, AI1
Rezvani, H1
Haghighi, S1
Ghadyani, M1
Attarian, H1
Lübbert, C1
Wiese, M1
Haupt, R1
Ruf, BR1
Sekine, Y1
Kubota, Y2
Kurihara, J1
Sheen, WC1
Chen, JS1
Wang, HM1
Yang, TS1
Liaw, CC1
Lin, YC1
Nomura, M1
Sato, H1
Fujimoto, N1
Matsumoto, T1
Rexer, H1
Famularo, G1
Minisola, G1
Grieco, A1
Miele, L1
Emberton, M1
Miyahara, T1
Oyabul, Y1
Hayashi, T1
Shimizu, S1
Tanaka, H2
Sternberg, CN1
Arlen, PM1
Gulley, JL1
Nakanishi, S1
Hatayama, T1
Azuma, K2
Bloomfield, D1
Luscombe, C1
Collins, R1
Trowman, R1
Norman, G1
Light, K1
Fenwick, E1
Palmer, S1
Riemsma, R1
Jacobsen, AB1
Ginman, C1
Jacobsen, IN1
Overn, S1
Iversen, JR1
Urnes, T2
Dahl, AA1
Veenstra, M1
Sandstad, B1
Bracarda, S1
Kibble, A1
Naito, S1
Tsukamoto, T1
Koga, H1
Harabayashi, T1
Andersson, L1
Edsmyr, F1
Esposti, PL1
Hedlund, PO1
Rönström, L1
Beckley, S1
Wajsman, LZ1
Slack, NH1
Murphy, GP5
Morozumi, M1
Takasu, H1
Okada, M1
Suwa, Y1
Noguchi, S1
Sakuramoto, T1
Shuin, T1
Kinoshita, Y1
Hosaka, M1
Maeda, N1
Nishizaki, S1
Furubayashi, T1
Datta, SN1
Thomas, K1
Matthews, PN1
Enomoto, Y1
Fukuhara, H1
Kurimoto, S1
Sugimoto, M1
Kimura, A1
Hosaka, Y1
Kitamura, T1
Schelin, S1
Palmqvist, E1
Madsen, M1
Bosson, S1
Eriksson, T1
Henricsson, A1
Josefsson, K1
Kobayashi, T1
Jo, Y1
Ikegami, M1
Furukawa, Y1
Morioka, M1
Kinugawa, K1
Ohta, S1
Culine, S1
Droz, JP1
Gibbons, RP1
Johnson, DE1
Prout, GR1
Schmidt, JD1
Soloway, MS1
Loening, SA1
Chu, TM1
Gaeta, JF1
Saroff, J1
Wajsman, Z1
Slack, N1
Scott, WW1
Catane, R3
Kaufman, JH1
Madajewicz, S1
Mittelman, A2
Kaufman, J1
Saha, PK1
Hyakutake, H1
Nomata, K1
Yushita, Y1
Kanetake, H1
Saito, Y1
Kaalhus, O1
Kobayashi, Y1
Yasunaga, Y1
Yoshioka, T1
Matsuda, M1
Oritani, K1
Kuyama, J1
Ohnishi, S1
Tada, Y1
Miyagawa, M1
Portnoĭ, AS1
Jahnsen, JU1
Karlsen, S1
Ogreid, P1
Haveland, H1
Trovåg, A1
Dreyer, CV1
Winter, CC1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
STAMPEDE: Systemic Therapy in Advancing or Metastatic Prostate Cancer: Evaluation of Drug Efficacy: A Multi-Stage Multi-Arm Randomised Controlled Trial[NCT00268476]Phase 2/Phase 311,992 participants (Actual)Interventional2005-07-08Active, not recruiting
A Randomized Phase II Trial Comparing Biomarker Directed Therapy Versus Clinician's Choice of Enzalutamide or Docetaxel in Patients With Advanced Prostate Cancer Post Abiraterone[NCT04015622]Phase 2100 participants (Anticipated)Interventional2020-10-07Recruiting
A Randomized, Double-blind, Comparative Study of Abiraterone Acetate Plus Low-Dose Prednisone Plus Androgen Deprivation Therapy (ADT) Versus ADT Alone in Newly Diagnosed Subjects With High-Risk, Metastatic Hormone-naive Prostate Cancer (mHNPC)[NCT01715285]Phase 31,209 participants (Actual)Interventional2013-02-12Completed
An Open-label, Phase I/IIa Dose Escalation and Expansion Study to Determine the Safety and Clinical Activity of an Immune Priming Cell Therapy (INKmune) in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC)[NCT06056791]Phase 1/Phase 230 participants (Anticipated)Interventional2023-11-30Not yet recruiting
A Single-center, Phase II Neoadjuvant Study of Abiraterone Acetate in the Treatment of Intraductal Carcinoma of the Prostate[NCT04736108]Phase 250 participants (Anticipated)Interventional2021-05-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Overall Survival (OS)

Overall survival was defined as the time from randomization to date of death from any cause. (NCT01715285)
Timeframe: Up to 66 months

Interventionmonths (Median)
Abiraterone Acetate+Prednisone+ADT53.32
Placebo + ADT36.53

Radiographic Progression-Free Survival (PFS)

Radiographic PFS was defined as the time (in months) interval from randomization to the first date of radiographic progression or death. Radiographic progression included progression by bone scan (according to modified Prostate Cancer Working Group 2 [PCWG2] criteria), defined as at least 2 new lesions on bone scan and progression of soft tissue lesions by computed tomography (CT) or magnetic resonance imaging (MRI) (according to Response Evaluation Criteria in Solid Tumors [RECIST] 1.1 criteria). As per the RECIST 1.1 guideline, progression requires a 20 percent (%) increase in the sum of diameters of all target lesions and a minimum absolute increase of 5 millimeter (mm) in the sum as compared to nadir sum of diameter. (NCT01715285)
Timeframe: Up to 44 months

InterventionMonths (Median)
Abiraterone Acetate+Prednisone+ADT33.02
Placebo + ADT14.78

Time to Initiation of Chemotherapy

Time to initiation of chemotherapy was defined as the time (in months) interval from the date of randomization to the date of initiation of cytotoxic chemotherapy for prostate cancer. (NCT01715285)
Timeframe: Up to 66 months

Interventionmonths (Median)
Abiraterone Acetate+Prednisone+ADTNA
Placebo + ADT57.59

Time to Pain Progression

"Time to pain progression was defined as the time (in months) interval from randomization to the first date a participant experienced a greater than or equal to (>=) 30 percent (%) increase in Brief Pain Inventory-Short Form (BPI-SF) from baseline in the BPI-SF worst pain intensity (Item 3) observed at 2 consecutive evaluations (>=4) weeks apart. BPI-SF was an 11-item questionnaire, designed to assess severity and impact of pain on daily functions. Total score ranged from 0 to 10 with 0 representing no pain and 10 representing pain as bad as you can imagine." (NCT01715285)
Timeframe: Up to 66 months

InterventionMonths (Median)
Abiraterone Acetate+Prednisone+ADT47.41
Placebo + ADT16.62

Time to Prostate-Specific Antigen (PSA) Progression

Time to PSA progression was defined as the time (in months) interval from the date of randomization to the date of PSA progression, according to PCWG2 criteria. PCWG2 defines PSA progression as the date that a 25 percent (%) or greater increase and an absolute increase of 2 nanogram per milliliter (ng/mL) or more from the nadir is documented, which is confirmed by a second value obtained 3 or more weeks later. (NCT01715285)
Timeframe: Up to 66 months

InterventionMonths (Median)
Abiraterone Acetate+Prednisone+ADT33.31
Placebo + ADT7.43

Time to Skeletal-Related Event

Time to skeletal-related event was defined as the earliest of the following: clinical or pathological fracture, spinal cord compression, palliative radiation to bone, or surgery to bone. (NCT01715285)
Timeframe: Up to 66 months

Interventionmonths (Median)
Abiraterone Acetate+Prednisone+ADTNA
Placebo + ADTNA

Time to Subsequent Therapy for Prostate Cancer

Time to subsequent therapy was defined as the time (in months) interval from the date of randomization to the date of initiation of subsequent therapy for prostate cancer. (NCT01715285)
Timeframe: Up to 66 months

InterventionMonths (Median)
Abiraterone Acetate+Prednisone+ADT54.87
Placebo + ADT21.22

Reviews

17 reviews available for prednisolone and Cancer of Prostate

ArticleYear
Abiraterone acetate and prednisolone with or without enzalutamide for high-risk non-metastatic prostate cancer: a meta-analysis of primary results from two randomised controlled phase 3 trials of the STAMPEDE platform protocol.
    Lancet (London, England), 2022, 01-29, Volume: 399, Issue:10323

    Topics: Abiraterone Acetate; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Chemotherapy, Adjuv

2022
Novel androgen axis systemic therapies for metastatic hormone-sensitive prostate cancer.
    Current opinion in urology, 2017, Volume: 27, Issue:6

    Topics: Androgen Antagonists; Androgens; Androstenes; Antineoplastic Agents, Hormonal; Antineoplastic Combin

2017
What is the optimal systemic treatment of men with metastatic, hormone-naive prostate cancer? A STOPCAP systematic review and network meta-analysis.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2018, 05-01, Volume: 29, Issue:5

    Topics: Abiraterone Acetate; Androgen Antagonists; Antineoplastic Combined Chemotherapy Protocols; Disease P

2018
[Case of malignant lymphoma of the prostate complicated with prostate adenocarcinoma].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 2009, Volume: 100, Issue:7

    Topics: Adenocarcinoma; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic

2009
[Scleroderma-like skin sclerosis induced by docetaxel chemotherapy for hormone refractory prostate cancer: a case report].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 2010, Volume: 101, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Drug Resistance, Neoplasm; Humans;

2010
[A case of primary malignant lymphoma of the prostate presenting as urinary retention].
    Hinyokika kiyo. Acta urologica Japonica, 2010, Volume: 56, Issue:10

    Topics: Aged, 80 and over; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Ag

2010
Role of second-line systemic treatment post-docetaxel in metastatic castrate resistant prostate cancer- current strategies and future directions.
    Anti-cancer agents in medicinal chemistry, 2011, Volume: 11, Issue:3

    Topics: Androstenes; Androstenols; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cl

2011
Novel therapeutic strategies for metastatic prostate cancer in the post-docetaxel setting.
    The oncologist, 2011, Volume: 16, Issue:11

    Topics: Androstenes; Androstenols; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Ca

2011
Abiraterone acetate in castration-resistant prostate cancer.
    Anti-cancer drugs, 2012, Volume: 23, Issue:3

    Topics: Abiraterone Acetate; Androgen Antagonists; Androstadienes; Clinical Trials as Topic; Docetaxel; Huma

2012
[Antisense oligonucleotide therapy for patients with castration-resistant prostate cancer].
    Nihon rinsho. Japanese journal of clinical medicine, 2011, Volume: 69 Suppl 5

    Topics: Castration; Docetaxel; Humans; Male; Oligonucleotides, Antisense; Prednisolone; Prostatic Neoplasms;

2011
[Toxic hepatitis and liver failure under therapy with flutamide].
    Der Internist, 2004, Volume: 45, Issue:3

    Topics: Aged; Anti-Inflammatory Agents; Antineoplastic Agents, Hormonal; Biopsy, Needle; Chemical and Drug I

2004
Satraplatin in the treatment of hormone-refractory prostate cancer.
    BJU international, 2005, Volume: 96, Issue:7

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Humans;

2005
The changing pattern of management for hormone-refractory, metastatic prostate cancer.
    Prostate cancer and prostatic diseases, 2006, Volume: 9, Issue:3

    Topics: Androgen Antagonists; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocol

2006
A systematic review of the effectiveness of docetaxel and mitoxantrone for the treatment of metastatic hormone-refractory prostate cancer.
    British journal of cancer, 2006, Aug-21, Volume: 95, Issue:4

    Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Drug Res

2006
[Primary non-Hodgkin lymphoma of the prostate: a case report].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1993, Volume: 84, Issue:11

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cyclophosphamide; Dau

1993
Chemotherapy in advanced androgen-independent prostate cancer 1990-1999: a decade of progress?
    Annals of oncology : official journal of the European Society for Medical Oncology, 2000, Volume: 11, Issue:12

    Topics: Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemothe

2000
[Chemotherapy of prostatic cancer].
    Voprosy onkologii, 1985, Volume: 31, Issue:9

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide;

1985

Trials

21 trials available for prednisolone and Cancer of Prostate

ArticleYear
Abiraterone acetate plus prednisolone for metastatic patients starting hormone therapy: 5-year follow-up results from the STAMPEDE randomised trial (NCT00268476).
    International journal of cancer, 2022, 08-01, Volume: 151, Issue:3

    Topics: Abiraterone Acetate; Aged; Androgen Antagonists; Antineoplastic Combined Chemotherapy Protocols; Fol

2022
Cost-utility analysis of adding abiraterone acetate plus prednisone/prednisolone to long-term hormone therapy in newly diagnosed advanced prostate cancer in England: Lifetime decision model based on STAMPEDE trial data.
    PloS one, 2022, Volume: 17, Issue:6

    Topics: Abiraterone Acetate; Acetates; Androgen Antagonists; Cost-Benefit Analysis; Hormones; Humans; Male;

2022
Abiraterone acetate plus prednisolone with or without enzalutamide for patients with metastatic prostate cancer starting androgen deprivation therapy: final results from two randomised phase 3 trials of the STAMPEDE platform protocol.
    The Lancet. Oncology, 2023, Volume: 24, Issue:5

    Topics: Abiraterone Acetate; Androgen Antagonists; Androgens; Antineoplastic Combined Chemotherapy Protocols

2023
Abiraterone plus Prednisone in Metastatic, Castration-Sensitive Prostate Cancer.
    The New England journal of medicine, 2017, 07-27, Volume: 377, Issue:4

    Topics: Abiraterone Acetate; Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Combined C

2017
Abiraterone plus Prednisone in Metastatic, Castration-Sensitive Prostate Cancer.
    The New England journal of medicine, 2017, 07-27, Volume: 377, Issue:4

    Topics: Abiraterone Acetate; Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Combined C

2017
Abiraterone plus Prednisone in Metastatic, Castration-Sensitive Prostate Cancer.
    The New England journal of medicine, 2017, 07-27, Volume: 377, Issue:4

    Topics: Abiraterone Acetate; Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Combined C

2017
Abiraterone plus Prednisone in Metastatic, Castration-Sensitive Prostate Cancer.
    The New England journal of medicine, 2017, 07-27, Volume: 377, Issue:4

    Topics: Abiraterone Acetate; Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Combined C

2017
Abiraterone plus Prednisone in Metastatic, Castration-Sensitive Prostate Cancer.
    The New England journal of medicine, 2017, 07-27, Volume: 377, Issue:4

    Topics: Abiraterone Acetate; Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Combined C

2017
Abiraterone plus Prednisone in Metastatic, Castration-Sensitive Prostate Cancer.
    The New England journal of medicine, 2017, 07-27, Volume: 377, Issue:4

    Topics: Abiraterone Acetate; Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Combined C

2017
Abiraterone plus Prednisone in Metastatic, Castration-Sensitive Prostate Cancer.
    The New England journal of medicine, 2017, 07-27, Volume: 377, Issue:4

    Topics: Abiraterone Acetate; Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Combined C

2017
Abiraterone plus Prednisone in Metastatic, Castration-Sensitive Prostate Cancer.
    The New England journal of medicine, 2017, 07-27, Volume: 377, Issue:4

    Topics: Abiraterone Acetate; Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Combined C

2017
Abiraterone plus Prednisone in Metastatic, Castration-Sensitive Prostate Cancer.
    The New England journal of medicine, 2017, 07-27, Volume: 377, Issue:4

    Topics: Abiraterone Acetate; Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Combined C

2017
Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy.
    The New England journal of medicine, 2017, 07-27, Volume: 377, Issue:4

    Topics: Abiraterone Acetate; Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Combined C

2017
Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy.
    The New England journal of medicine, 2017, 07-27, Volume: 377, Issue:4

    Topics: Abiraterone Acetate; Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Combined C

2017
Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy.
    The New England journal of medicine, 2017, 07-27, Volume: 377, Issue:4

    Topics: Abiraterone Acetate; Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Combined C

2017
Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy.
    The New England journal of medicine, 2017, 07-27, Volume: 377, Issue:4

    Topics: Abiraterone Acetate; Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Combined C

2017
Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy.
    The New England journal of medicine, 2017, 07-27, Volume: 377, Issue:4

    Topics: Abiraterone Acetate; Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Combined C

2017
Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy.
    The New England journal of medicine, 2017, 07-27, Volume: 377, Issue:4

    Topics: Abiraterone Acetate; Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Combined C

2017
Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy.
    The New England journal of medicine, 2017, 07-27, Volume: 377, Issue:4

    Topics: Abiraterone Acetate; Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Combined C

2017
Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy.
    The New England journal of medicine, 2017, 07-27, Volume: 377, Issue:4

    Topics: Abiraterone Acetate; Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Combined C

2017
Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy.
    The New England journal of medicine, 2017, 07-27, Volume: 377, Issue:4

    Topics: Abiraterone Acetate; Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Combined C

2017
Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy.
    The New England journal of medicine, 2017, 07-27, Volume: 377, Issue:4

    Topics: Abiraterone Acetate; Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Combined C

2017
Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy.
    The New England journal of medicine, 2017, 07-27, Volume: 377, Issue:4

    Topics: Abiraterone Acetate; Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Combined C

2017
Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy.
    The New England journal of medicine, 2017, 07-27, Volume: 377, Issue:4

    Topics: Abiraterone Acetate; Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Combined C

2017
Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy.
    The New England journal of medicine, 2017, 07-27, Volume: 377, Issue:4

    Topics: Abiraterone Acetate; Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Combined C

2017
Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy.
    The New England journal of medicine, 2017, 07-27, Volume: 377, Issue:4

    Topics: Abiraterone Acetate; Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Combined C

2017
Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy.
    The New England journal of medicine, 2017, 07-27, Volume: 377, Issue:4

    Topics: Abiraterone Acetate; Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Combined C

2017
Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy.
    The New England journal of medicine, 2017, 07-27, Volume: 377, Issue:4

    Topics: Abiraterone Acetate; Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Combined C

2017
Gemcitabine-oxaliplatin plus prednisolone is active in patients with castration-resistant prostate cancer for whom docetaxel-based chemotherapy failed.
    British journal of cancer, 2014, May-13, Volume: 110, Issue:10

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Antineoplastic Combined Ch

2014
A randomized phase II trial comparing weekly taxotere plus prednisolone versus prednisolone alone in androgen-independent prostate cancer.
    Frontiers of radiation therapy and oncology, 2008, Volume: 41

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Dise

2008
Oral vinorelbine as first line chemotherapy in unfit elderly patients with hormone-refractory prostate cancer.
    Journal of chemotherapy (Florence, Italy), 2008, Volume: 20, Issue:3

    Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Antineoplastic Com

2008
A randomized, double-blind, placebo-controlled phase II study of vandetanib plus docetaxel/prednisolone in patients with hormone-refractory prostate cancer.
    Cancer biotherapy & radiopharmaceuticals, 2009, Volume: 24, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Surviva

2009
[Combined treatment of metastatic hormone-resistant prostate cancer].
    Voprosy onkologii, 2009, Volume: 55, Issue:4

    Topics: Aged; Androgen Antagonists; Androgens; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chem

2009
Docetaxel-prednisolone combination therapy for Japanese patients with hormone-refractory prostate cancer: a single institution experience.
    Japanese journal of clinical oncology, 2010, Volume: 40, Issue:11

    Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Docetaxe

2010
Metronomic oral cyclophosphamide prednisolone chemotherapy is an effective treatment for metastatic hormone-refractory prostate cancer after docetaxel failure.
    Anticancer research, 2010, Volume: 30, Issue:10

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Docetaxel

2010
Prolonged treatment with three-weekly docetaxel plus daily prednisolone for metastatic castration-resistant prostate cancer: a multicenter, phase II, open-label, non-comparative, extension study in Japan.
    International journal of clinical oncology, 2013, Volume: 18, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Drug Administration Schedule; Drug-

2013
Efficacy of taxotere, thalidomide, and prednisolone in patients with hormone-resistant metastatic prostate cancer.
    Urology journal, 2012,Fall, Volume: 9, Issue:4

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Disease-Fre

2012
Weekly docetaxel and prednisolone versus prednisolone alone in androgen-independent prostate cancer: a randomized phase II study.
    European urology, 2007, Volume: 52, Issue:6

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Humans; Male; Mi

2007
Docetaxel plus prednisolone for the treatment of metastatic hormone-refractory prostate cancer: a multicenter Phase II trial in Japan.
    Japanese journal of clinical oncology, 2008, Volume: 38, Issue:5

    Topics: Aged; Alopecia; Anorexia; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Prot

2008
Chemotherapy in metastatic, hormone refractory prostatic cancer using chlorambucil in combination with prednisolone versus conjugate, prednimustine (Leo 1031).
    Urology, 1981, Volume: 17, Issue:5

    Topics: Aged; Antineoplastic Agents; Chlorambucil; Clinical Trials as Topic; Drug Therapy, Combination; Huma

1981
Is prednisolone as good as flutamide in hormone refractory metastatic carcinoma of the prostate?
    The Journal of urology, 1997, Volume: 158, Issue:1

    Topics: Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flutamide; Humans; M

1997
Antiemetic efficacy of prednisolone: a placebo-controlled trial in patients with advanced prostatic cancer treated with estramustine phosphate.
    Scandinavian journal of urology and nephrology, 1998, Volume: 32, Issue:2

    Topics: Aged; Antiemetics; Antineoplastic Agents, Alkylating; Area Under Curve; Double-Blind Method; Estramu

1998
[Clinical evaluation of low dose glucocorticoid therapy for hormone-refractory prostate cancer].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 2000, Volume: 91, Issue:4

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Dexamethasone; Drug Adm

2000
[Chemotherapy of advanced prostate cancer].
    Voprosy onkologii, 1977, Volume: 23, Issue:12

    Topics: Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Dacarbazine; Diethylstilbestrol; Drug Eval

1977

Other Studies

60 other studies available for prednisolone and Cancer of Prostate

ArticleYear
Synthesis and biological analysis of prostate-specific membrane antigen-targeted anticancer prodrugs.
    Journal of medicinal chemistry, 2010, Nov-11, Volume: 53, Issue:21

    Topics: Antigens, Surface; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Drug Screening Assays, An

2010
Abiraterone acetate versus nonsteroidal antiandrogen with androgen deprivation therapy for high-risk metastatic hormone-sensitive prostate cancer.
    The Prostate, 2022, Volume: 82, Issue:1

    Topics: Abiraterone Acetate; Androgen Antagonists; Anilides; Antineoplastic Combined Chemotherapy Protocols;

2022
Re: Abiraterone Acetate and Prednisolone With or Without Enzalutamide for High-risk Non-metastatic Prostate Cancer: A Meta-analysis of Primary Results from Two Randomized Controlled Phase 3 Trials of the STAMPEDE Platform Protocol.
    European urology, 2022, Volume: 81, Issue:6

    Topics: Abiraterone Acetate; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Clinical Trials, Ph

2022
The Swedish national guidelines on prostate cancer, part 1: early detection, diagnostics, staging, patient support and primary management of non-metastatic disease.
    Scandinavian journal of urology, 2022, Volume: 56, Issue:4

    Topics: Gonadotropin-Releasing Hormone; Humans; Iodine; Male; Neoplasm Staging; Povidone; Prednisolone; Pros

2022
Comparison of Weekly Low Dose Docetaxel with the Standard Protocol in Hormone-resistant Metastatic Prostate Cancer.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2022, Volume: 32, Issue:8

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Hormones; Humans; Male; Prednisolon

2022
Treatment strategies and outcomes in a long-term registry study of patients with high-risk metastatic hormone-naïve prostate cancer in Japan: An interim analysis of the J-ROCK study.
    International journal of urology : official journal of the Japanese Urological Association, 2022, Volume: 29, Issue:9

    Topics: Abiraterone Acetate; Androgen Antagonists; Androgens; Antineoplastic Combined Chemotherapy Protocols

2022
Treatment options for patients with prostate cancer who develop metastatic disease after hormonal therapy.
    Clinical advances in hematology & oncology : H&O, 2019, Volume: 17, Issue:7

    Topics: Abiraterone Acetate; Absorptiometry, Photon; Aged; Antineoplastic Combined Chemotherapy Protocols; B

2019
Considering bone health in the treatment of prostate cancer bone metastasis based on the results of the ERA-223 trial.
    International journal of clinical oncology, 2019, Volume: 24, Issue:12

    Topics: Abiraterone Acetate; Bone Density; Bone Neoplasms; Double-Blind Method; Humans; Male; Prednisolone;

2019
Bacterial steroid-17,20-desmolase is a taxonomically rare enzymatic pathway that converts prednisone to 1,4-androstanediene-3,11,17-trione, a metabolite that causes proliferation of prostate cancer cells.
    The Journal of steroid biochemistry and molecular biology, 2020, Volume: 199

    Topics: Adrenal Glands; Androgens; Androstadienes; Cell Line, Tumor; Cell Proliferation; Clostridiales; Gluc

2020
[Comparison of Abiraterone Acetate Plus Prednisolone and Combined Androgen Blockade in High-risk Metastatic Hormone-Sensitive Prostate Cancer].
    Hinyokika kiyo. Acta urologica Japonica, 2020, Volume: 66, Issue:12

    Topics: Abiraterone Acetate; Androgen Antagonists; Androgens; Antineoplastic Combined Chemotherapy Protocols

2020
Commentary on: Abiraterone Plus Prednisolone in Metastatic, Castration-sensitive Prostate Cancer.
    Urology, 2017, Volume: 109

    Topics: Abiraterone Acetate; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Castration; Diseas

2017
Real-world uptake, safety profile and outcomes of docetaxel in newly diagnosed metastatic prostate cancer.
    BJU international, 2018, Volume: 121, Issue:2

    Topics: Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents; Antineoplastic Combined Chemot

2018
Appendix 1: Cancer of the Prostate: eUpdate published online 28 September 2017 (http://www.esmo.org/Guidelines/Genitourinary-Cancers/Cancer-of-the-Prostate).
    Annals of oncology : official journal of the European Society for Medical Oncology, 2018, 10-01, Volume: 29, Issue:Suppl 4

    Topics: Androgen Antagonists; Androstenes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemothe

2018
Combination therapies in prostate cancer: proceed with caution.
    The Lancet. Oncology, 2019, Volume: 20, Issue:3

    Topics: Abiraterone Acetate; Double-Blind Method; Humans; Male; Prednisolone; Prednisone; Prostatic Neoplasm

2019
Antitumour activity of abiraterone acetate against metastatic castration-resistant prostate cancer progressing after docetaxel and enzalutamide (MDV3100).
    Annals of oncology : official journal of the European Society for Medical Oncology, 2013, Volume: 24, Issue:7

    Topics: Aged; Aged, 80 and over; Androstenes; Androstenols; Antineoplastic Agents; Antineoplastic Combined C

2013
Interactions of abiraterone, eplerenone, and prednisolone with wild-type and mutant androgen receptor: a rationale for increasing abiraterone exposure or combining with MDV3100.
    Cancer research, 2013, May-01, Volume: 73, Issue:9

    Topics: Androstenols; Humans; Male; Phenylthiohydantoin; Prednisolone; Prostatic Neoplasms; Receptors, Andro

2013
[Successful treatment with docetaxel and prednisolone for paxlitaxel and carboplatin-resistant prostate cancer].
    Hinyokika kiyo. Acta urologica Japonica, 2013, Volume: 59, Issue:5

    Topics: Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Antineopl

2013
[A case on hemodialysis with castration-resistant prostate cancer which responded to combination chemotherapy with docetaxel and prednisolone].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2013, Volume: 40, Issue:9

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Castration; Docetaxel; Humans; Kidney Failure,

2013
Cutaneous metastasis of prostate carcinoma treated with radiotherapy: a case presentation.
    BMC research notes, 2014, Aug-08, Volume: 7

    Topics: Aged; Humans; Male; Mitoxantrone; Prednisolone; Prostatic Neoplasms; Skin Neoplasms

2014
Translating Clinical Evidence-Based Medicine into the Real World: Single-Center Experience with Cabazitaxel in Metastatic Prostate Cancer Patients.
    Chemotherapy, 2016, Volume: 61, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Docetaxel; Evidence-Based Med

2016
Unusual co-occurrence of Evans syndrome and pure red cell aplasia in elderly patient with prostate cancer.
    Annals of hematology, 2016, Volume: 95, Issue:10

    Topics: Adenocarcinoma; Aged, 80 and over; Anemia, Hemolytic, Autoimmune; Humans; Male; Paraneoplastic Syndr

2016
Dexamethasone did not suppress immune boosting by personalized peptide vaccination for advanced prostate cancer patients.
    The Prostate, 2008, Dec-01, Volume: 68, Issue:16

    Topics: Aged; Antibody Formation; Antineoplastic Agents, Hormonal; Cancer Vaccines; Combined Modality Therap

2008
Docetaxel in combination with prednisolone for hormone refractory prostate cancer.
    Japanese journal of clinical oncology, 2010, Volume: 40, Issue:1

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Dose-Respons

2010
Temporary improvement in activities of daily living after steroid therapy for the treatment of anti-Hu antibody-associated syndrome in a patient with advanced prostate cancer.
    Journal of pain and symptom management, 2011, Volume: 41, Issue:2

    Topics: Activities of Daily Living; Adenocarcinoma; ELAV Proteins; Glucocorticoids; Humans; Male; Middle Age

2011
[A case of castration-refractory prostate cancer showing marked decrease of serum PSA level after zoledronic acid treatment with estramustine phosphate and prednisolone].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Castration; Diphosphonates; Es

2011
Interstitial pneumonitis induced by bicalutamide given for prostate cancer.
    International journal of clinical oncology, 2011, Volume: 16, Issue:6

    Topics: Aged; Androgen Antagonists; Anilides; Bone Neoplasms; Castration; Humans; Lung Diseases, Interstitia

2011
[A case of prednisolone therapy for radiation-induced hemorrhagic cystitis].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 2011, Volume: 102, Issue:3

    Topics: Administration, Oral; Aged; Cystitis; Glucocorticoids; Hemorrhage; Humans; Male; Prednisolone; Prost

2011
5α-reductase inhibitors, antiviral and anti-tumor activities of some steroidal cyanopyridinone derivatives.
    International journal of biological macromolecules, 2012, Jan-01, Volume: 50, Issue:1

    Topics: 5-alpha Reductase Inhibitors; Animals; Antineoplastic Agents; Antiviral Agents; Cell Line, Tumor; Ch

2012
Primary cutaneous nocardiosis caused by Nocardia beijingensis in an immunocompromised patient with chemotherapy for advanced prostate cancer.
    The Journal of dermatology, 2012, Volume: 39, Issue:8

    Topics: Aged; Anti-Bacterial Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols;

2012
Cerebellar axial postural tremor complicating radiotherapy for prostate cancer.
    Parkinsonism & related disorders, 2012, Volume: 18, Issue:5

    Topics: Aged; Cerebellar Ataxia; Glucocorticoids; Humans; Male; Posture; Prednisolone; Prostatic Neoplasms;

2012
Interactions of abiraterone, eplerenone, and prednisolone with wild-type and mutant androgen receptor: a rationale for increasing abiraterone exposure or combining with MDV3100.
    Cancer research, 2012, May-01, Volume: 72, Issue:9

    Topics: Androgen Receptor Antagonists; Androgens; Androstenes; Androstenols; Anilides; Benzamides; Binding,

2012
Cabazitaxel rechallenge at prostate-specific antigen relapse after previous cabazitaxel and docetaxel chemotherapy: case report.
    Clinical genitourinary cancer, 2012, Volume: 10, Issue:3

    Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Docetaxel; Drug R

2012
[Cabazitaxel after docetaxel: a new option in metastatic castration-resistant prostate cancer].
    Bulletin du cancer, 2012, Volume: 99, Issue:9

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Doc

2012
NICE guidance on abiraterone for castration-resistant metastatic prostate cancer previously treated with a docetaxel-containing regimen.
    The Lancet. Oncology, 2012, Volume: 13, Issue:8

    Topics: Androstenes; Androstenols; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Pro

2012
[A case of dermatomyositis associated with prostatic carcinoma: a case report].
    Hinyokika kiyo. Acta urologica Japonica, 2004, Volume: 50, Issue:2

    Topics: Adenocarcinoma; Aged; Anti-Inflammatory Agents; Antineoplastic Agents, Hormonal; Dermatomyositis; Di

2004
A modified low-dose regimen of mitoxantrone and prednisolone in patients with androgen-independent prostate cancer.
    Japanese journal of clinical oncology, 2004, Volume: 34, Issue:6

    Topics: Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Disease Progression; Drug Administrati

2004
Interstitial pneumonitis related to flutamide monotherapy for prostate cancer.
    International journal of urology : official journal of the Japanese Urological Association, 2004, Volume: 11, Issue:9

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Flutamide; Humans; Lung Di

2004
[Therapy of painful bone metastases in patients with prostate carcinoma. The AP 32/02 Study of the AUO].
    Der Urologe. Ausg. A, 2004, Volume: 43, Issue:9

    Topics: Antineoplastic Agents; Bone Neoplasms; Diphosphonates; Humans; Ibandronic Acid; Male; Mitoxantrone;

2004
Fulminant liver failure caused by cyproterone.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2005, Volume: 37, Issue:9

    Topics: Aged; Alanine Transaminase; Androgen Antagonists; Cyproterone; Gastrointestinal Agents; Glutamyl Ami

2005
Prolonging survival in prostate cancer: chemotherapy will have an important role.
    BJU international, 2005, Volume: 96, Issue:1

    Topics: Androgen Antagonists; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Drug Resistance, Ne

2005
[A case of malignant lymphoma of the prostate].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 2005, Volume: 96, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; D

2005
Docetaxel-based regimens, the standard of care for metastatic androgen-insensitive prostate cancer.
    Future oncology (London, England), 2005, Volume: 1, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase III as Topic; Docetaxel; Huma

2005
[Adenocarcinoma of the prostate associated with anti Jo-1 antibody positive polymyositis].
    Hinyokika kiyo. Acta urologica Japonica, 2006, Volume: 52, Issue:4

    Topics: Adenocarcinoma; Aged; Anti-Inflammatory Agents; Antibodies, Antinuclear; Humans; Magnetic Resonance

2006
[A case of hormone-refractory prostate cancer (HRPC) with tumor fever responding to docetaxel plus prednisolone therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:6

    Topics: Aged; Androgen Antagonists; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy

2006
Editorial comment on: Weekly docetaxel and prednisolone versus prednisolone alone in androgen-independent prostate cancer: a randomized phase II study.
    European urology, 2007, Volume: 52, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Humans; Male; Prednisolone; Prostatic Neo

2007
The preliminary results of docetaxel-prednisolone combination therapy for the Japanese patients with hormone-refractory prostate cancer.
    Hinyokika kiyo. Acta urologica Japonica, 2007, Volume: 53, Issue:2

    Topics: Administration, Oral; Aged; Ambulatory Care; Docetaxel; Drug Administration Schedule; Drug Therapy,

2007
American Society of Clinical Oncology--43rd annual meeting. Research into therapeutics: Part 3.
    IDrugs : the investigational drugs journal, 2007, Volume: 10, Issue:8

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Prot

2007
Cyclophosphamide-prednisolone therapy in advanced prostatic carcinoma.
    Scandinavian journal of urology and nephrology. Supplementum, 1980, Volume: 55

    Topics: Acid Phosphatase; Cyclophosphamide; Drug Therapy, Combination; Humans; Male; Neoplasm Metastasis; Pr

1980
[Malignant lymphoma of the prostate--a case report].
    Hinyokika kiyo. Acta urologica Japonica, 1993, Volume: 39, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Humans; Lymphom

1993
[Secondary non-Hodgkin lymphoma of the prostate: a case report].
    Hinyokika kiyo. Acta urologica Japonica, 1996, Volume: 42, Issue:7

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Humans; Lymphom

1996
[A case of hormone-refractory prostate cancer responsive to low-dose prednisolone therapy].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1997, Volume: 88, Issue:6

    Topics: Aged; Antineoplastic Agents, Hormonal; Glucocorticoids; Humans; Male; Prednisolone; Prostate-Specifi

1997
The use of estramustine and prednimustine versus prednimustine alone in advanced metastatic prostatic cancer patients who have received prior irradiation.
    The Journal of urology, 1979, Volume: 121, Issue:6

    Topics: Chlorambucil; Drug Therapy, Combination; Estramustine; Humans; Male; Nausea; Neoplasm Metastasis; Ni

1979
Prednimustine therapy for advanced prostatic cancer.
    British journal of urology, 1978, Volume: 50, Issue:1

    Topics: Adrenal Glands; Aged; Chemical Phenomena; Chemistry; Chlorambucil; Drug Combinations; Humans; Male;

1978
Clinical experience with estramustine phosphate and predinimustine, two steroidal alkylating agents compounds [proceedings].
    Cancer treatment reports, 1978, Volume: 62, Issue:8

    Topics: Chlorambucil; Estramustine; Humans; Male; Nitrogen Mustard Compounds; Prednisolone; Prostatic Neopla

1978
Combined therapy of advanced prostatic carcinoma with estramustine and prednimustine.
    The Journal of urology, 1977, Volume: 117, Issue:3

    Topics: Aged; Antineoplastic Agents; Chlorambucil; Drug Therapy, Combination; Estramustine; Humans; Male; Mi

1977
Non-specific granulomatous prostatitis treated with steroids.
    Hinyokika kiyo. Acta urologica Japonica, 1991, Volume: 37, Issue:8

    Topics: Aged; Biopsy, Needle; Diagnosis, Differential; Drug Administration Schedule; Granuloma; Humans; Male

1991
Weekly low-dose adriamycin in hormone-resistant metastatic cancer of the prostate.
    Scandinavian journal of urology and nephrology, 1987, Volume: 21, Issue:1

    Topics: Aged; Bone Neoplasms; Doxorubicin; Drug Resistance; Estradiol Congeners; Humans; Infusions, Intraven

1987
[Triple malignancy including bladder carcinoma, prostate carcinoma and malignant lymphoma: a case report].
    Hinyokika kiyo. Acta urologica Japonica, 1989, Volume: 35, Issue:11

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell;

1989
High-dose medroxyprogesterone acetate versus prednisolone in hormone-resistant prostatic cancer. A pilot study.
    European urology, 1985, Volume: 11, Issue:1

    Topics: Acid Phosphatase; Aged; Antineoplastic Agents; Humans; Male; Medroxyprogesterone; Medroxyprogesteron

1985
Applications of the dermo-jet in urology.
    The Journal of urology, 1970, Volume: 104, Issue:4

    Topics: Animals; Cicatrix; Cystoscopes; Dogs; Female; Glucocorticoids; Humans; Injections; Male; Methods; Me

1970