prednisolone has been researched along with Bronchial Hyperreactivity in 31 studies
Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.
Bronchial Hyperreactivity: Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of prednisolone, salbutamol or theophylline treatment were studied in guinea pigs on bronchial hyperreactivity induced by chronic administration of PAF, (subsequently measuring respiratory flow after an intravenous injection of histamine) and the chemokinesis of leucocytes in vitro." | 7.68 | Effects of prednisolone, salbutamol and theophylline on bronchial hyperreactivity and leucocyte chemokinesis in guinea pigs. ( Berga, P; Fernández, AG; Gristwood, RW; Llupiá, J, 1991) |
| "Five patients with asthma were treated with 20 mg of prednisolone orally for 2 preoperative days and 80 mg of methylprednisolone IV immediately before and after surgery." | 3.71 | Preoperative steroid therapy inhibits cytokine production in the lung parenchyma in asthmatic patients. ( Ayabe, H; Fukushima, C; Kohno, S; Matsuse, H; Mitsuta, K; Obase, Y; Shimoda, T, 2001) |
| "Non-GCS-responsive BHR asthma was defined as failure of reduction of BHR to methacholine after a 2-week course of oral prednisolone (30 mg/day)." | 3.70 | Corticosteroid resistance in mild asthma: markers of persistent inflammation. ( Asai, S; Kohno, S; Matsuo, N; Matsuse, H; Obase, Y; Shimoda, T, 1999) |
| "Described is a guinea pig model of allergic asthma, in which animals are sensitized by intraperitoneal injections of ovalbumin complexed with aluminum hydroxide to elicit an IgE response." | 3.68 | Induction by aerosol allergen of sustained and nonspecific IgE-mediated airway hyperreactivity in the guinea pig. ( DeLeo, JJ; Handley, DA; Havill, AM, 1992) |
| "The effects of prednisolone, salbutamol or theophylline treatment were studied in guinea pigs on bronchial hyperreactivity induced by chronic administration of PAF, (subsequently measuring respiratory flow after an intravenous injection of histamine) and the chemokinesis of leucocytes in vitro." | 3.68 | Effects of prednisolone, salbutamol and theophylline on bronchial hyperreactivity and leucocyte chemokinesis in guinea pigs. ( Berga, P; Fernández, AG; Gristwood, RW; Llupiá, J, 1991) |
| "Prednisolone did not inhibit either of these responses." | 1.35 | The suppressive effects of YM-58483/BTP-2, a store-operated Ca2+ entry blocker, on inflammatory mediator release in vitro and airway responses in vivo. ( Ishikawa, J; Ohga, K; Shimizu, Y; Takezawa, R; Yamada, T; Yoshino, T, 2008) |
| "To evaluate the effect of clinical treatment for sinusitis in patients with rhinitis and/or asthma on symptoms and on bronchial hyperresponsiveness to methacholine." | 1.30 | Improvement of bronchial hyperresponsiveness in asthmatic children treated for concomitant sinusitis. ( Naspitz, CK; Oliveira, CA; Rachelefsky, GS; Solé, D, 1997) |
| "To determine whether bronchial asthma is associated with increased levels of sICAM-1 in serum and to assess the effects of therapy on these levels, the concentrations of sICAM-1 were measured in sera of healthy donors and asthmatic patients." | 1.29 | Soluble intercellular adhesion molecule 1 (ICAM-1) antigen in sera of bronchial asthmatics. ( Kaji, M; Marukawa, M; Ono, T; Shiota, Y; Wilson, JG, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (38.71) | 18.2507 |
| 2000's | 17 (54.84) | 29.6817 |
| 2010's | 2 (6.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goto, K | 3 |
| Chiba, Y | 3 |
| Sakai, H | 3 |
| Misawa, M | 3 |
| Miyagawa, N | 1 |
| Iwasaki, H | 1 |
| Kato, T | 1 |
| Tanaka, M | 1 |
| Shibata, T | 1 |
| Wakitani, K | 1 |
| Hirano, Y | 1 |
| Shichijo, M | 1 |
| Ikeda, M | 1 |
| Kitaura, M | 1 |
| Tsuchida, J | 1 |
| Asanuma, F | 1 |
| Yanagimoto, T | 1 |
| Furue, Y | 1 |
| Imura, K | 1 |
| Yasui, K | 1 |
| Arimura, A | 1 |
| Ketkar, M | 1 |
| Shrier, D | 1 |
| Nagao, K | 1 |
| Akabane, H | 1 |
| Masuda, T | 2 |
| Komai, M | 1 |
| Tanaka, H | 3 |
| Nagai, H | 5 |
| Bush, A | 1 |
| Bonfils, P | 2 |
| Avan, P | 1 |
| Chen, ML | 1 |
| Lin, BF | 1 |
| Amano, T | 1 |
| Nishihira, J | 1 |
| Miki, I | 1 |
| Malinvaud, D | 1 |
| Ohga, K | 1 |
| Takezawa, R | 1 |
| Yoshino, T | 1 |
| Yamada, T | 2 |
| Shimizu, Y | 1 |
| Ishikawa, J | 1 |
| Iwashita, K | 1 |
| Kawasaki, H | 1 |
| Sawada, M | 1 |
| In, M | 1 |
| Mataki, Y | 1 |
| Kuwabara, T | 1 |
| Hirahara, M | 1 |
| Whyte, MK | 1 |
| Choudry, NB | 1 |
| Ind, PW | 1 |
| Iwama, T | 1 |
| Tsuruoka, N | 1 |
| Koda, A | 2 |
| Shiota, Y | 1 |
| Wilson, JG | 1 |
| Marukawa, M | 1 |
| Ono, T | 2 |
| Kaji, M | 1 |
| Oliveira, CA | 1 |
| Solé, D | 1 |
| Naspitz, CK | 1 |
| Rachelefsky, GS | 1 |
| Renkema, TE | 1 |
| Kerstjens, HA | 1 |
| Schouten, JP | 1 |
| Vonk, JM | 1 |
| Koëter, GH | 1 |
| Postma, DS | 1 |
| Matsuse, H | 2 |
| Shimoda, T | 2 |
| Matsuo, N | 1 |
| Obase, Y | 2 |
| Asai, S | 1 |
| Kohno, S | 2 |
| Rosi, E | 1 |
| Scano, G | 1 |
| Lipworth, BJ | 1 |
| Musoh, K | 1 |
| Maeda, Y | 1 |
| Inagaki, N | 2 |
| Kawada, N | 1 |
| Takizawa, T | 1 |
| Takahashi, Y | 1 |
| Mitsuta, K | 1 |
| Fukushima, C | 1 |
| Ayabe, H | 1 |
| Handley, DA | 1 |
| DeLeo, JJ | 1 |
| Havill, AM | 1 |
| Asano, M | 1 |
| Inamura, N | 1 |
| Nakahara, K | 1 |
| Nagayoshi, A | 1 |
| Isono, T | 1 |
| Hamada, K | 1 |
| Oku, T | 1 |
| Notsu, Y | 1 |
| Kohsaka, M | 1 |
| Nakajima, A | 1 |
| Tsuji, F | 1 |
| Shimazawa, T | 1 |
| Goto, S | 1 |
| Yoshitake, K | 1 |
| Llupiá, J | 1 |
| Fernández, AG | 1 |
| Berga, P | 1 |
| Gristwood, RW | 1 |
1 review available for prednisolone and Bronchial Hyperreactivity
| Article | Year |
|---|---|
Association of sputum parameters with clinical and functional measurements in asthma.
Topics: Albuterol; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactivity; Eosinophils; Forced Expirato | 2000 |
1 trial available for prednisolone and Bronchial Hyperreactivity
| Article | Year |
|---|---|
The importance of serum IgE for level and longitudinal change in airways hyperresponsiveness in COPD.
Topics: Aged; Anti-Inflammatory Agents; Bronchial Hyperreactivity; Bronchial Provocation Tests; Budesonide; | 1998 |
29 other studies available for prednisolone and Bronchial Hyperreactivity
| Article | Year |
|---|---|
Glucocorticoids inhibited airway hyperresponsiveness through downregulation of CPI-17 in bronchial smooth muscle.
Topics: Acetylcholine; Animals; Ascaris; Beclomethasone; Bronchi; Bronchial Hyperreactivity; Down-Regulation | 2008 |
Two pharmacological phases in antigen-induced immediate airway response in rats.
Topics: Administration, Inhalation; Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Agonists; Albutero | 2008 |
Mechanism of inhibitory effect of prednisolone on RhoA upregulation in human bronchial smooth muscle cells.
Topics: Anti-Inflammatory Agents; Asthma; Bronchi; Bronchial Hyperreactivity; Gene Expression Regulation; Gl | 2010 |
Prostanoid DP receptor antagonists suppress symptomatic asthma-like manifestation by distinct actions from a glucocorticoid in rats.
Topics: Acetylcholine; Aged; Animals; Antigens; Asthma; Bronchial Hyperreactivity; Chemokines; Female; Gene | 2011 |
An allergic reaction to intraarterial nonionic contrast material.
Topics: Adult; Airway Obstruction; Bronchial Hyperreactivity; Carotid Artery, Common; Cerebral Angiography; | 2003 |
Effect of MX-68 on airway inflammation and hyperresponsiveness in mice and guinea-pigs.
Topics: 2-Aminoadipic Acid; Acetylcholine; Administration, Inhalation; Allergens; Animals; Body Weight; Bron | 2004 |
Classification of phenotypes.
Topics: Asthma; Bronchial Hyperreactivity; Child; Glucocorticoids; Humans; Phenotype; Prednisolone; Respirat | 2004 |
Non-specific bronchial hyperresponsiveness is a risk factor for steroid insensitivity in nasal polyposis.
Topics: Administration, Oral; Aerosols; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti | 2004 |
Effects of triterpenoid-rich extracts of Ganoderma tsugae on airway hyperreactivity and Th2 responses in vivo.
Topics: Animals; Antibody Formation; Asthma; Bronchial Hyperreactivity; Drugs, Chinese Herbal; Female; Inter | 2007 |
Blockade of macrophage migration inhibitory factor (MIF) prevents the antigen-induced response in a murine model of allergic airway inflammation.
Topics: Animals; Anti-Inflammatory Agents; Antibodies, Blocking; Asthma; Bronchial Hyperreactivity; Bronchoa | 2007 |
Influence of allergy in patients with nasal polyposis after endoscopic sinus surgery.
Topics: Adult; Asthma; Beclomethasone; Bronchial Hyperreactivity; Bronchial Provocation Tests; Combined Moda | 2008 |
The suppressive effects of YM-58483/BTP-2, a store-operated Ca2+ entry blocker, on inflammatory mediator release in vitro and airway responses in vivo.
Topics: Anilides; Animals; Anti-Inflammatory Agents; Blood Cells; Bronchial Hyperreactivity; Bronchoconstric | 2008 |
Shortening of the induction period of allergic asthma in cynomolgus monkeys by Ascaris suum and house dust mite.
Topics: Administration, Inhalation; Administration, Oral; Airway Resistance; Allergens; Androstadienes; Anim | 2008 |
Glucocorticoids ameliorate antigen-induced bronchial smooth muscle hyperresponsiveness by inhibiting upregulation of RhoA in rats.
Topics: Acetylcholine; Animals; Anti-Asthmatic Agents; Antigens, Helminth; Ascaris suum; Asthma; Beclomethas | 2008 |
Bronchial hyperresponsiveness in patients recovering from acute severe asthma.
Topics: Acute Disease; Adolescent; Adult; Aged; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchial Provoc | 1993 |
Effect of murine recombinant interleukin-5 on bronchial reactivity in guinea-pigs.
Topics: Animals; Bronchial Hyperreactivity; Cromolyn Sodium; Eosinophilia; Guinea Pigs; Interleukin-5; Ketot | 1993 |
Soluble intercellular adhesion molecule 1 (ICAM-1) antigen in sera of bronchial asthmatics.
Topics: Acute Disease; Administration, Oral; Adult; Aged; Allergens; Animals; Anti-Asthmatic Agents; Asthma; | 1996 |
Improvement of bronchial hyperresponsiveness in asthmatic children treated for concomitant sinusitis.
Topics: Administration, Intranasal; Adolescent; Anti-Infective Agents; Asthma; Bronchial Hyperreactivity; Br | 1997 |
Corticosteroid resistance in mild asthma: markers of persistent inflammation.
Topics: Administration, Oral; Adult; Asthma; Asthma, Exercise-Induced; Bronchial Hyperreactivity; Drug Resis | 1999 |
Therapeutic ratio of inhaled fluticasone.
Topics: Administration, Inhalation; Androstadienes; Anti-Inflammatory Agents; Bronchial Hyperreactivity; Eos | 2000 |
Effect of a novel anti-allergic agent, HSR-609, on antigen-induced airway hyperresponsiveness in mice.
Topics: Acetylcholine; Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Benzoxepins; Bronchial Hyper | 2000 |
Role of mast cells in antigen-induced airway inflammation and bronchial hyperresponsiveness in rats.
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents; Bronchial Hyperreactivity; Bronchoalveolar Lavage | 2001 |
Preoperative steroid therapy inhibits cytokine production in the lung parenchyma in asthmatic patients.
Topics: Administration, Oral; Adult; Aged; Asthma; Bronchial Hyperreactivity; Cytokines; Female; Gene Expres | 2001 |
Induction by aerosol allergen of sustained and nonspecific IgE-mediated airway hyperreactivity in the guinea pig.
Topics: Acetylcholine; Aerosols; Allergens; Animals; Asthma; Bronchial Hyperreactivity; Diphenhydramine; Gui | 1992 |
[Diagnosis, physiopathology and therapy of bronchial asthma: discussion].
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Asthma; Bronchial Hyperreactivity; Desensitiza | 1992 |
A 5-lipoxygenase inhibitor, FR110302, suppresses airway hyperresponsiveness and lung eosinophilia induced by Sephadex particles in rats.
Topics: Acetylcholine; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Chromones; Dextrans | 1992 |
[Application of adrenal cortex hormones in the treatment of asthma].
Topics: Administration, Inhalation; Arachidonic Acid; Asthma; Beclomethasone; Bronchi; Bronchial Hyperreacti | 1992 |
Participation of collagenase and elastase in LPS-induced airway hyperresponsiveness in guinea pigs.
Topics: Acetylcholine; Airway Obstruction; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; | 1991 |
Effects of prednisolone, salbutamol and theophylline on bronchial hyperreactivity and leucocyte chemokinesis in guinea pigs.
Topics: Albuterol; Animals; Asthma; Bronchial Hyperreactivity; Chemotaxis, Leukocyte; Guinea Pigs; Male; Pla | 1991 |