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prednisolone and Bone Diseases, Metabolic

prednisolone has been researched along with Bone Diseases, Metabolic in 29 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Bone Diseases, Metabolic: Diseases that affect the METABOLIC PROCESSES of BONE TISSUE.

Research Excerpts

ExcerptRelevanceReference
"Despite a far lower cumulative GC dose in comparison with patients treated with systemic corticosteroids continuously, after adjusting for BMI and lung function, osteoporosis of the lumbar spine was most frequent in patients receiving > 1,000 mg of prednisolone cumulatively, administered in multiple courses for the treatment of exacerbations of COPD."3.71Dual energy X-ray absorptiometry outcomes in male COPD patients after treatment with different glucocorticoid regimens. ( Dekhuijzen, PN; Dubois, EF; Röder, E; Schweitzer, DH; Zwinderman, AE, 2002)
"At the distal radius, osteopenia was found in all the groups."2.69Bone loss in long-term renal transplantation: histopathology and densitometry analysis. ( Adams, JE; Crowley, V; Cueto-Manzano, AM; France, MW; Freemont, AJ; Gokal, R; Hutchison, AJ; Konel, S; Mawer, B, 1999)
"Investigations revealed distal renal tubular acidosis with severe metabolic bone disease as an extra-glandular manifestation of primary SS."1.56Primary Sjogren's syndrome manifesting with distal renal tubular acidosis and severe metabolic bone disease. ( Bhandari, S; Jain, G; Kalra, S; Vasnik, G, 2020)
" No relationship was observed between osteoporosis and age, sex, body mass index, duration of hemodialysis therapy, cumulative dosage of any drugs, or use of pulsed methylprednisolone therapy."1.35Osteoporosis and related risk factors in renal transplant recipients. ( Ahmadpoor, P; Ghafari, A; Makhdoomi, K; Rahimi, E; Reisi, S; Sepehrvand, N, 2009)
"Osteoporosis or osteopenia was present in all the diagnostic groups."1.35Cytokines, bone turnover markers and weight change in candidates for lung transplantation. ( Bjørtuft, O; Boe, J; Førli, L; Halse, J; Mellbye, OJ; Vatn, M, 2008)
" Those receiving a higher CsA dosage (<2."1.33Bone mineral density in long-term Chinese heart transplant recipients: a cross-sectional study. ( Chen, YH; Chou, NK; Kuo, HL; Su, IC; Wang, SS; Yang, RS, 2006)
"Osteopenia was common in both groups (44."1.32Lower serum beta-CrossLaps in male cardiac transplant recipients treated without prednisolone. ( Drexel, H; Gouya, G; Hergan, K; Höfle, G; Holzmüller, H; Hubmann, M; Langer, P, 2003)
"Rat models of osteopenia include ovariectomy and long-term glucocorticoid treatment."1.31Comparison of osteopenia after gastrectomy, ovariectomy and prednisolone treatment in the young female rat. ( Andersson, N; Håkanson, R; Lehto-Axtelius, D; Surve, VV, 2001)
" The aim of the present study was to evaluate if growth hormone administration would have an anabolic effect on rat bone when given to animals also receiving a high dosage of glucocorticoid."1.29Growth hormone is not able to counteract osteopenia of rat cortical bone induced by glucocorticoid with protracted effect. ( Andreassen, TT; Brüel, A; Ortoft, G; Oxlund, H, 1995)
"Radiologic or clinical evidence of osteopenia in the spine was not found."1.28Limitations of quantitative CT in corticosteroid induced osteopenia. ( Glaros, D; Kalef-Ezra, J; Karantanas, AH, 1991)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (31.03)18.2507
2000's12 (41.38)29.6817
2010's7 (24.14)24.3611
2020's1 (3.45)2.80

Authors

AuthorsStudies
Jain, G1
Kalra, S1
Vasnik, G1
Bhandari, S1
Ohlsson, C1
Nilsson, KH1
Henning, P1
Wu, J1
Gustafsson, KL1
Poutanen, M1
Lerner, UH1
Movérare-Skrtic, S1
Bhadada, SK1
Dhaliwal, R1
Dhiman, V1
Rao, SD1
Jensen, EA1
White, AM1
Liu, P1
Yee, K1
Waber, B1
Monk, HM1
Zhang, H1
Ahmadpoor, P1
Reisi, S1
Makhdoomi, K1
Ghafari, A1
Sepehrvand, N1
Rahimi, E1
Sharma, A1
Pinto Pereira, LM1
Capildeo, K1
Charles, K1
Teelucksingh, S1
Ding, M1
Cheng, L1
Bollen, P1
Schwarz, P1
Overgaard, S1
Kriel, M1
Sayers, A1
Fraser, WD1
Williams, AM1
Koch, A1
Zacharowski, K1
Probert, CS1
Tobias, JH1
Tang, XL1
Qin, L1
Kwok, AW1
Zhu, TY1
Kun, EW1
Hung, VW1
Griffith, JF1
Leung, PC1
Li, EK1
Tam, LS1
Höfle, G1
Holzmüller, H1
Gouya, G1
Hergan, K1
Hubmann, M1
Langer, P1
Drexel, H1
Lian, KC1
Lang, TF1
Keyak, JH1
Modin, GW1
Rehman, Q1
Do, L1
Lane, NE1
Chou, NK1
Su, IC1
Kuo, HL1
Chen, YH1
Yang, RS1
Wang, SS1
Kikuchi, Y1
Imakiire, T1
Yamada, M1
Saigusa, T1
Hyodo, T1
Kushiyama, T1
Higashi, K1
Hyodo, N1
Yamamoto, K1
Suzuki, S1
Miura, S1
Førli, L1
Mellbye, OJ1
Halse, J1
Bjørtuft, O1
Vatn, M1
Boe, J1
Unoki, E1
Ortoft, G2
Oxlund, H2
Brüel, A1
Andreassen, TT1
Okazaki, Y1
Tsurukami, H1
Nishida, S1
Okimoto, N1
Aota, S1
Takeda, S1
Nakamura, T1
Ebeling, PR1
Thomas, DM1
Erbas, B1
Hopper, JL1
Szer, J1
Grigg, AP1
Cueto-Manzano, AM1
Konel, S1
Hutchison, AJ1
Crowley, V1
France, MW1
Freemont, AJ1
Adams, JE1
Mawer, B1
Gokal, R1
Ozaki, D1
Shirai, Y1
Nakayama, Y1
Yoshihara, K1
Huzita, T1
Lange, U1
Boss, B1
Teichmann, J1
Stracke, H1
Neeck, G1
Belvisi, MG1
Wicks, SL1
Battram, CH1
Bottoms, SE1
Redford, JE1
Woodman, P1
Brown, TJ1
Webber, SE1
Foster, ML1
Matsumoto, H1
Ishihara, K1
Hasegawa, T1
Umeda, B1
Niimi, A1
Hino, M1
Surve, VV1
Andersson, N1
Lehto-Axtelius, D1
Håkanson, R1
Dubois, EF1
Röder, E1
Dekhuijzen, PN1
Zwinderman, AE1
Schweitzer, DH1
Karantanas, AH1
Kalef-Ezra, J1
Glaros, D1
Geusens, P1
Dequeker, J1
Nijs, J1
Verstraeten, A1
Bramm, E1
Graziani, G1
Aroldi, A1
Castelnovo, C1
Bondatti, F1
DeVecchi, A1
Ponticelli, C1

Reviews

1 review available for prednisolone and Bone Diseases, Metabolic

ArticleYear
Fibrogenesis Imperfecta Ossium.
    Calcified tissue international, 2019, Volume: 104, Issue:5

    Topics: Alkaline Phosphatase; Biopsy; Bone and Bones; Bone Diseases, Metabolic; Collagen; Diphosphonates; Di

2019

Trials

2 trials available for prednisolone and Bone Diseases, Metabolic

ArticleYear
Effect of risedronate on high-dose corticosteroid-induced bone loss in patients with glomerular disease.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2007, Volume: 22, Issue:6

    Topics: Adolescent; Adult; Aged; Bone Density Conservation Agents; Bone Diseases, Metabolic; Dose-Response R

2007
Bone loss in long-term renal transplantation: histopathology and densitometry analysis.
    Kidney international, 1999, Volume: 55, Issue:5

    Topics: Absorptiometry, Photon; Adult; Age Factors; Anti-Inflammatory Agents; Azathioprine; Bone Density; Bo

1999

Other Studies

26 other studies available for prednisolone and Bone Diseases, Metabolic

ArticleYear
Primary Sjogren's syndrome manifesting with distal renal tubular acidosis and severe metabolic bone disease.
    BMJ case reports, 2020, Jun-01, Volume: 13, Issue:6

    Topics: Absorptiometry, Photon; Acidosis, Renal Tubular; Adolescent; Antirheumatic Agents; Arthralgia; Bone

2020
WNT16 overexpression partly protects against glucocorticoid-induced bone loss.
    American journal of physiology. Endocrinology and metabolism, 2018, 06-01, Volume: 314, Issue:6

    Topics: Animals; Bone Density; Bone Diseases, Metabolic; Cytoprotection; Female; Glucocorticoids; Mice; Mice

2018
Determinants of Severe Metabolic Bone Disease in Very Low-Birth-Weight Infants with Severe Bronchopulmonary Dysplasia Admitted to a Tertiary Referral Center.
    American journal of perinatology, 2016, Volume: 33, Issue:1

    Topics: Birth Weight; Bone Diseases, Metabolic; Bronchopulmonary Dysplasia; Comorbidity; Female; Furosemide;

2016
Osteoporosis and related risk factors in renal transplant recipients.
    Transplantation proceedings, 2009, Volume: 41, Issue:7

    Topics: Absorptiometry, Photon; Adolescent; Adult; Bone Density; Bone Diseases, Metabolic; Creatinine; Cyclo

2009
Steroid-induced iatrogenic disease after treating for pseudothrombocytopenia.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2011, Volume: 17, Issue:1

    Topics: Bone Diseases, Metabolic; Diabetes Mellitus; Diagnostic Errors; Glucocorticoids; Humans; Hyperglycem

2011
Glucocorticoid induced osteopenia in cancellous bone of sheep: validation of large animal model for spine fusion and biomaterial research.
    Spine, 2010, Feb-15, Volume: 35, Issue:4

    Topics: Alkaline Phosphatase; Animals; Biocompatible Materials; Biomarkers; Bone and Bones; Bone Diseases, M

2010
IL-6 may modulate the skeletal response to glucocorticoids during exacerbations of inflammatory bowel disease.
    Calcified tissue international, 2010, Volume: 86, Issue:5

    Topics: Adult; Bone Diseases, Metabolic; Bone Remodeling; Bone Resorption; Cell Proliferation; Collagen Type

2010
Alterations of bone geometry, density, microarchitecture, and biomechanical properties in systemic lupus erythematosus on long-term glucocorticoid: a case-control study using HR-pQCT.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2013, Volume: 24, Issue:6

    Topics: Absorptiometry, Photon; Adult; Biomechanical Phenomena; Bone Density; Bone Diseases, Metabolic; Case

2013
Lower serum beta-CrossLaps in male cardiac transplant recipients treated without prednisolone.
    Transplant international : official journal of the European Society for Organ Transplantation, 2003, Volume: 16, Issue:7

    Topics: Bone Density; Bone Diseases, Metabolic; Collagen; Cross-Sectional Studies; Cyclosporine; Drug Therap

2003
Differences in hip quantitative computed tomography (QCT) measurements of bone mineral density and bone strength between glucocorticoid-treated and glucocorticoid-naive postmenopausal women.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2005, Volume: 16, Issue:6

    Topics: Absorptiometry, Photon; Age Factors; Aged; Aged, 80 and over; Bone Density; Bone Diseases, Metabolic

2005
Bone mineral density in long-term Chinese heart transplant recipients: a cross-sectional study.
    Transplantation proceedings, 2006, Volume: 38, Issue:7

    Topics: Adult; Aged; Body Size; Bone Density; Bone Diseases, Metabolic; Cross-Sectional Studies; Cyclosporin

2006
Cytokines, bone turnover markers and weight change in candidates for lung transplantation.
    Pulmonary pharmacology & therapeutics, 2008, Volume: 21, Issue:1

    Topics: Adult; Anti-Inflammatory Agents; Biomarkers; Body Weight; Bone Density; Bone Diseases, Metabolic; C-

2008
[Effect of human PTH on steroid-induced osteopenia: a histomorphometric study of decalcified and undecalcified trabecular bone sections in rat].
    Nihon Seikeigeka Gakkai zasshi, 1995, Volume: 69, Issue:10

    Topics: Animals; Bone and Bones; Bone Density; Bone Diseases, Metabolic; Female; Osteogenesis; Parathyroid H

1995
Qualitative alterations of cortical bone in female rats after long-term administration of growth hormone and glucocorticoid.
    Bone, 1996, Volume: 18, Issue:6

    Topics: Administration, Oral; Aging; Animals; Bone Density; Bone Development; Bone Diseases, Metabolic; Bone

1996
Growth hormone is not able to counteract osteopenia of rat cortical bone induced by glucocorticoid with protracted effect.
    Bone, 1995, Volume: 17, Issue:6

    Topics: Animals; Biomechanical Phenomena; Body Weight; Bone and Bones; Bone Diseases, Metabolic; Female; Fem

1995
Prednisolone prevents decreases in trabecular bone mass and strength by reducing bone resorption and bone formation defect in adjuvant-induced arthritic rats.
    Bone, 1998, Volume: 23, Issue:4

    Topics: Animals; Arthritis, Experimental; Bone Density; Bone Diseases, Metabolic; Bone Resorption; Collagen;

1998
Mechanisms of bone loss following allogeneic and autologous hemopoietic stem cell transplantation.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1999, Volume: 14, Issue:3

    Topics: Adult; Bone Density; Bone Diseases, Metabolic; Bone Remodeling; Cross-Sectional Studies; Cyclosporin

1999
Multiple fish vertebra deformity in child with systemic lupus erythematosus: a case report.
    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2000, Volume: 67, Issue:4

    Topics: Anti-Inflammatory Agents; Bone Density; Bone Diseases, Metabolic; Calcitonin; Child; Female; Humans;

2000
Bone mineral density and biochemical markers of bone metabolism in late onset rheumatoid arthritis and polymyalgia rheumatica--a prospective study on the influence of glucocorticoid therapy.
    Zeitschrift fur Rheumatologie, 2000, Volume: 59 Suppl 2

    Topics: Aged; Alkaline Phosphatase; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Bone Den

2000
Therapeutic benefit of a dissociated glucocorticoid and the relevance of in vitro separation of transrepression from transactivation activity.
    Journal of immunology (Baltimore, Md. : 1950), 2001, Feb-01, Volume: 166, Issue:3

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Bone Diseases, Metabolic; Budesonide; Desox

2001
Effects of inhaled corticosteroid and short courses of oral corticosteroids on bone mineral density in asthmatic patients : a 4-year longitudinal study.
    Chest, 2001, Volume: 120, Issue:5

    Topics: Absorptiometry, Photon; Administration, Inhalation; Administration, Oral; Anti-Asthmatic Agents; Ast

2001
Comparison of osteopenia after gastrectomy, ovariectomy and prednisolone treatment in the young female rat.
    Acta orthopaedica Scandinavica, 2001, Volume: 72, Issue:5

    Topics: Animals; Bone Density; Bone Diseases, Metabolic; Disease Models, Animal; Femur; Gastrectomy; Ovariec

2001
Dual energy X-ray absorptiometry outcomes in male COPD patients after treatment with different glucocorticoid regimens.
    Chest, 2002, Volume: 121, Issue:5

    Topics: Absorptiometry, Photon; Administration, Oral; Aged; Anti-Inflammatory Agents; Body Mass Index; Bone

2002
Limitations of quantitative CT in corticosteroid induced osteopenia.
    Acta radiologica (Stockholm, Sweden : 1987), 1991, Volume: 32, Issue:4

    Topics: Adult; Bone Diseases, Metabolic; Collagen Diseases; Female; Humans; Kidney Transplantation; Male; Mi

1991
Prevention and treatment of osteopenia in the ovariectomized rat: effect of combined therapy with estrogens, 1-alpha vitamin D, and prednisolone.
    Calcified tissue international, 1991, Volume: 48, Issue:2

    Topics: Animals; Bone Density; Bone Diseases, Metabolic; Drug Therapy, Combination; Estradiol; Female; Hydro

1991
Ciclosporin and calcium metabolism in renal transplanted patients.
    Nephron, 1991, Volume: 57, Issue:4

    Topics: Alkaline Phosphatase; Bone and Bones; Bone Diseases, Metabolic; Calcium; Cyclosporins; Humans; Intes

1991