Page last updated: 2024-11-06

prednisolone and Blood Loss, Postoperative

prednisolone has been researched along with Blood Loss, Postoperative in 5 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Research Excerpts

Excerpt	Relevance	Reference
"Acquired hemophilia A is a rare but potentially fatal disease."	1.42	A case of acquired hemophilia A diagnosed after percutaneous endoscopic gastrostomy. ( Arakura, N; Ito, A; Ito, T; Komatsu, M; Okamura, T; Sakai, H; Suga, T; Tanaka, E, 2015)
"A 35-year-old myopic man with juvenile open angle glaucoma was referred to us with fluctuating intraocular pressure (IOP) and progression in his only seeing left eye."	1.42	Restoration of pretrabeculectomy visual acuity and a functioning filtering bleb in an eye with delayed suprachoroidal haemorrhage following trabeculectomy. ( Balijepalli, P; Gupta, S; Senthil, S, 2015)

Research

Studies (5)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	5 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Park, SK	1
Kim, J	1
Kim, JM	1
Yeon, JY	1
Shim, WS	1
Lee, DW	1
Aveline, C	1
Le Hetet, H	1
Le Roux, A	1
Bonnet, F	1
Okamura, T	1
Komatsu, M	1
Ito, A	1
Ito, T	1
Suga, T	1
Arakura, N	1
Sakai, H	1
Tanaka, E	1
Senthil, S	1
Gupta, S	1
Balijepalli, P	1
Balderramo, D	1
Bordas, JM	1
Sendino, O	1
Abraldes, JG	1
Navasa, M	1
Llach, J	1
Cardenas, A	1

Clinical Trials (1)

Trial Overview

Trial			Phase	Enrollment	Study Type	Start Date	Status
Effect of Steroids on Post-tonsillectomy Morbidities[NCT02401529]			Phase 2	100 participants (Actual)	Interventional	2013-01-31	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Average Amount of Meal Per Day

adequacy of meals (inadequate, adequate) (NCT02401529)
Timeframe: 3 days

Intervention	participants (Number)
	inadequate	adequate
IV Dexamethasone and Oral Prednisolone	16	34
Placebo	27	23

Average Frequency of Meals Per Day

average frequency of meals (1 meal, 2 meals, if more specify) (NCT02401529)
Timeframe: average number of meals consumed per day for the 1st three days post-surgery

Intervention	participants (Number)
	1 meal	2 meals	3 meals
IV Dexamethasone and Oral Prednisolone	2	20	28
Placebo	1	34	15

Duration of Post-operative Nausea

Postoperative nausea duration (no nausea,1 day, 2 days, 3 days, 4 days, if more specify) (NCT02401529)
Timeframe: 7 days

Intervention	participants (Number)
	no nausea	one day	two days	three days
IV Dexamethasone and Oral Prednisolone	33	3	14	0
Placebo	21	8	15	6

Duration of Post-operative Pain

4 selections (1 day, 2 days, 3 days, if more specify) (NCT02401529)
Timeframe: number of days at which pain was experienced within the the 1st sevn days post -surgery

Intervention	participants (Number)
	one day	two days	three days
IV Dexamethasone and Oral Prednisolone	36	11	3
Placebo	23	19	8

Maximum Severity of Post-operative Pain

5 grades (pain free, low disability and low intensity, low disability and high intensity, high disability and moderate intensity, high disability and severly limiting) (NCT02401529)
Timeframe: The severest pain grade felt within a week

Intervention	participants (Number)
	Low disability and low intensity	high disability and moderate intensity	high disability and high intensity
IV Dexamethasone and Oral Prednisolone	37	13	0
Placebo	26	21	3

Occurence of Post-operative Nausea

Postoperative nausea occurence (yes, no) (NCT02401529)
Timeframe: 7 days

Intervention	participants (Number)
	yes	no
IV Dexamethasone and Oral Prednisolone	17	33
Placebo	29	21

Occurence of Postoperative Vomiting

Postoperative vomiting occurrence (yes, no) (NCT02401529)
Timeframe: 7 days

Intervention	participants (Number)
	yes	no
IV Dexamethasone and Oral Prednisolone	25	25
Placebo	36	14

Onset of 1st Post-operative Oral Intake

feeding onset (1st day i. surgery day, 2nd day, 3rd day) (NCT02401529)
Timeframe: Onset of 1st post-operative oral intake recorded within the 1st 3days post-surgery

Intervention	participants (Number)
	surgery day	1st day after surgery
IV Dexamethasone and Oral Prednisolone	46	4
Placebo	37	13

Onset of Post-operative Nausea

Postoperative nausea onset (no nausea, immediate, 1st day, 2nd day, 3rd day, 4th day, 5th day, 6th day, 7th day) (NCT02401529)
Timeframe: onset of 1st ocurence of nausea attack within the 1st week post-surgery

Intervention	participants (Number)
	no nausea	immediately	1st day	immediately and 1st day
IV Dexamethasone and Oral Prednisolone	33	10	4	3
Placebo	21	8	11	10

Total Number of Post-operative Vomiting Episodes

Postoperative vomiting number of attacks (no vomiting,1, 2, 3, if more specify) (NCT02401529)
Timeframe: total number of post-operative vomiting episodes which were experienced within the 1st week post-surgery

Intervention	participants (Number)
	no vomiting	once	twice	three times	more than 3 times
IV Dexamethasone and Oral Prednisolone	25	13	7	4	1
Placebo	14	9	19	8	0

Trials

1 trial available for prednisolone and Blood Loss, Postoperative

Article	Year
Effects of oral prednisolone on recovery after tonsillectomy. The Laryngoscope, 2015, Volume: 125, Issue:1 Topics: Adenoidectomy; Administration, Oral; Adolescent; Adult; Child; Child, Preschool; Cohort Studies; End	2015

Other Studies

4 other studies available for prednisolone and Blood Loss, Postoperative

Article	Year
A survey of the administration of prednisolone versus ibuprofen analgesic protocols after ambulatory tonsillectomy. Anaesthesia, critical care & pain medicine, 2015, Volume: 34, Issue:5 Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-In	2015
A case of acquired hemophilia A diagnosed after percutaneous endoscopic gastrostomy. Clinical journal of gastroenterology, 2015, Volume: 8, Issue:5 Topics: Aged; Deglutition Disorders; Gastrostomy; Hemophilia A; Humans; Immunosuppressive Agents; Male; Post	2015
Restoration of pretrabeculectomy visual acuity and a functioning filtering bleb in an eye with delayed suprachoroidal haemorrhage following trabeculectomy. BMJ case reports, 2015, Dec-09, Volume: 2015 Topics: Adult; Blister; Choroid Hemorrhage; Glaucoma, Open-Angle; Glucocorticoids; Humans; Male; Mydriatics;	2015
Complications after ERCP in liver transplant recipients. Gastrointestinal endoscopy, 2011, Volume: 74, Issue:2 Topics: Aged; Cholangiopancreatography, Endoscopic Retrograde; Cholangitis; Contrast Media; Creatinine; Fema	2011