prednisolone and Bacterial Eye Infections studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Research Excerpts

Excerpt	Relevance	Reference
"The Steroids for Corneal Ulcers Trial (SCUT) was a randomized, double-masked, placebo-controlled trial that overall found no effect of adding topical corticosteroids to topical moxifloxacin hydrochloride in bacterial keratitis."	5.19	Early addition of topical corticosteroids in the treatment of bacterial keratitis. ( Acharya, NR; Glidden, DV; Lietman, TM; Mascarenhas, J; McLeod, SD; Oldenburg, CE; Rajaraman, R; Ravindran, M; Ray, KJ; Srinivasan, M; Sun, CQ; Zegans, ME, 2014)
"The Steroids for Corneal Ulcers Trial (SCUT) was a randomized, double-masked, placebo-controlled trial assessing outcomes in patients with culture positive bacterial corneal ulcers randomized to receive prednisolone phosphate or placebo."	5.17	Emerging moxifloxacin resistance in Pseudomonas aeruginosa keratitis isolates in South India. ( Acharya, NR; Borkar, DS; Lalitha, P; Lietman, TM; Mascarenhas, J; McLeod, SD; Oldenburg, CE; Porco, TC; Rajaraman, R; Ravindran, M; Ray, KJ; Srinivasan, M; Zegans, ME, 2013)
"In the Steroids for Corneal Ulcers Trial (SCUT), 500 corneal infections were treated with topical moxifloxacin."	5.17	Moxifloxacin susceptibility mediates the relationship between causative organism and clinical outcome in bacterial keratitis. ( Acharya, NR; Bharathi, MJ; Glidden, DV; Lalitha, P; Lietman, TM; Manikandan, P; Mascarenhas, J; Nardone, N; Oldenburg, CE; Rajaraman, R; Ravindran, M; Ray, KJ; Srinivasan, M, 2013)
"Baseline data from a 1:1 randomized, placebo-controlled, double-masked clinical trial comparing prednisolone phosphate, 1%, with placebo as adjunctive therapy for the treatment of bacterial corneal ulcers."	5.16	The steroids for corneal ulcers trial: study design and baseline characteristics. ( Acharya, NR; Glidden, DV; Hong, KC; Lalitha, P; Lee, SM; Lietman, TM; Mascarenhas, J; McLeod, SD; Oldenburg, CE; Rajaraman, R; Ravindran, M; Ray, KJ; Srinivasan, M; Zegans, ME, 2012)
"Subanalyses were performed on data collected in the Steroids for Corneal Ulcers Trial (SCUT), a large randomized controlled trial in which patients were treated with moxifloxacin and were randomly assigned to 1 of 2 adjunctive treatment arms: corticosteroid or placebo (4 times a day with subsequent reduction)."	5.16	Pseudomonas aeruginosa keratitis: outcomes and response to corticosteroid treatment. ( Acharya, NR; Glidden, D; Lalitha, P; Lietman, TM; Mascarenhas, J; McLeod, SD; Oldenburg, CE; Rajaraman, R; Ravindran, M; Ray, KJ; Srinivasan, M; Sy, A; Zegans, ME, 2012)
" He received an empirical antibiotic and antiviral agent intravenously followed by oral prednisolone until the etiology was identified; however, intraocular inflammation in the left eye continued to worsen, followed by the development of subretinal abscess in the contralateral eye."	3.81	Klebsiella Endophthalmitis as Retinal Vasculitis with Prostatic Abscess. ( Bae, SH; Jin, KW; Kim, E; Kim, H, 2015)
"Ciprofloxacin and prednisolone, but not an aminoglycoside and dexamethasone, were previously found to be effective in killing bacteria and reducing inflammation for the treatment of Pseudomonas keratitis."	3.69	Effectiveness of specific antibiotic/steroid combinations for therapy of experimental Pseudomonas aeruginosa keratitis. ( Callegan, MC; Engel, LS; Hill, JM; Hobden, JA; O'Callaghan, RJ; Reidy, JJ, 1995)
"We present a case of syphilis causing palmoplantar keratoderma and ocular disease in a patient with HIV infection, and discuss the differences in diagnosis and treatment of patients with both diseases."	2.45	Syphilitic palmoplantar keratoderma and ocular disease: a rare combination in an HIV-positive patient. ( Goreshi, R; Kirby, JS; Mahoney, N, 2009)
"We report a case of confirmed Mycoplasma pneumoniae infection in the setting of unilateral anterior uveitis and perineuritis without coexisting systemic manifestations."	1.43	Acute Mycoplasma pneumoniae infection presenting with unilateral anterior uveitis and perineuritis. ( Chen, WS; Perry, JT, 2016)
"Bacterial keratitis results in corneal scarring and subsequent visual impairment."	1.39	Improvement in corneal scarring following bacterial keratitis. ( Acharya, NR; Greninger, DA; Keenan, JD; Lietman, TM; Mascarenhas, J; McClintic, SM; Srinivasan, M, 2013)
"Bacterial endophthalmitis is a potential complication of ICL implantation."	1.35	Culture-positive endophthalmitis after implantation of intraocular Collamer lens. ( Cohen, JA; Davis, MJ; Dennis, RF; Epstein, RJ, 2009)
"Phlyctenular keratoconjunctivitis is a type IV hypersensitivity reaction to an inciting agent."	1.35	Phlyctenular keratoconjunctivitis in a patient with Staphylococcal blepharitis and ocular rosacea. ( Neiberg, MN; Sowka, J, 2008)
"To report a patient with vernal keratoconjunctivitis-induced shield ulcer superinfected with Staphylococcus aureus."	1.33	Secondary bacterial keratitis associated with shield ulcer caused by vernal conjunctivitis. ( Akova, YA; Gedik, S; Gür, S, 2006)
" These results suggest that either salt of prednisolone, when combined with ciprofloxacin, reduces ocular inflammation without affecting the antimicrobial efficacy of the antibiotic."	1.29	Prednisolone acetate or prednisolone phosphate concurrently administered with ciprofloxacin for the therapy of experimental Pseudomonas aeruginosa keratitis. ( Callegan, MC; Engel, LS; Hill, JM; Hobden, JA; O'Callaghan, RJ, 1993)
"A 27-year-old man with acquired immunodeficiency syndrome [AIDS] had endophthalmitis OS four years after a trabeculectomy was done."	1.28	Endophthalmitis due to Mycobacterium avium in a patient with AIDS. ( Cohen, JI; Saragas, SJ, 1990)

Research

Studies (62)

Authors

Clinical Trials (3)

Trial Overview

Trial Outcomes

Best Hard Contact Lens Corrected Visual Acuity Measured in logMAR, Correcting for Best Spectacle Corrected Visual Acuity at Enrollment

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	19 (30.65)	18.2507
2000's	17 (27.42)	29.6817
2010's	25 (40.32)	24.3611
2020's	1 (1.61)	2.80

Authors	Studies
Li, KH	1
Chen, SN	1
Bakhsh, SR	1
Ali, MH	1
Bhat, P	1
Moussa, K	1
Shantha, J	1
Schallhorn, JM	1
Wu, YT	1
Truong, TN	2
Tam, C	1
Mendoza, MN	2
Zhu, L	1
Evans, DJ	1
Fleiszig, SMJ	1
Pushker, N	1
Tejwani, LK	1
Bajaj, MS	1
Khurana, S	1
Velpandian, T	1
Chandra, M	1
Oldenburg, CE	11
Lalitha, P	10
Srinivasan, M	15
Rajaraman, R	10
Ravindran, M	9
Mascarenhas, J	12
Borkar, DS	1
Ray, KJ	12
Zegans, ME	9
McLeod, SD	9
Porco, TC	2
Lietman, TM	15
Acharya, NR	15
O'Brien, KS	2
Glidden, DV	6
Whitcher, JP	3
Kletke, SN	1
Brissette, AR	1
Gale, J	1
Keenan, JD	3
McClintic, SM	2
Prajna, NV	2
Sun, CQ	2
Jin, KW	1
Kim, E	1
Kim, H	1
Bae, SH	1
Perry, JT	1
Chen, WS	1
Höllhumer, R	1
Zairani Mz, A	1
Watson, S	1
AlKheraiji, NF	1
AlKheraiji, AF	1
Stone, DU	1
Karahocagil, MK	1
Demirok, A	1
Kiliç, A	1
Cinal, A	1
Caksen, H	1
Yasar, T	1
Mahalakshmi, R	2
Chidambaram, JD	1
Lee, S	1
Hong, KC	3
Zegans, M	1
McLeod, S	2
Paganelli, F	1
Cardillo, JA	1
Melo, LA	1
Lucena, DR	1
Silva, AA	1
Oliveira, AG	1
Höfling-Lima, AL	1
Nguyen, QD	1
Kuppermann, BD	1
Belfort, R	1
Davis, MJ	1
Epstein, RJ	1
Dennis, RF	1
Cohen, JA	1
Kirby, JS	1
Goreshi, R	1
Mahoney, N	1
Berger, EA	1
McClellan, SA	1
Barrett, RP	1
Hazlett, LD	1
Balzli, CL	1
McCormick, CC	1
Caballero, AR	1
Tang, A	1
O'Callaghan, RJ	4
Lee, SM	2
Sy, A	2
Glidden, D	2
Priya, JL	1
Balaskas, K	1
Spencer, S	1
D'Souza, Y	1
See, CW	1
Saravanan, S	1
Esterberg, EJ	1
Glaser, TS	1
Tu, EY	1
Greninger, DA	1
Prajna, L	2
Geetha, M	1
Karpagam, R	1
Manikandan, P	1
Bharathi, MJ	1
Nardone, N	1
Lee, EJ	1
Fleiszig, SM	1
Tunç, M	1
Durukan, H	1
Holden, BA	1
Sankaridurg, PR	1
Sweeney, DF	1
Stretton, S	1
Naduvilath, TJ	1
Rao, GN	1
Wilhelmus, KR	1
Jones, DB	1
Gedik, S	1
Akova, YA	1
Gür, S	1
Chen, A	1
Ramos-Esteban, JC	1
Jeng, BH	1
Neiberg, MN	1
Sowka, J	1
Apel, A	1
Campbell, I	3
Rootman, DS	3
Daniel, E	1
Alexander, R	1
Chacko, S	1
Engel, LS	2
Callegan, MC	2
Hobden, JA	3
Reidy, JJ	2
Hill, JM	3
Kernacki, KA	1
Berk, RS	1
Cordonnier, M	1
Caspers-Velu, LE	1
Jacquemin, C	1
Van Nechel, C	1
Tombroff, M	1
Scott, IU	1
Flynn, HW	1
Feuer, W	1
Pflugfelder, SC	1
Alfonso, EC	1
Forster, RK	1
Miller, D	1
Holland, GN	1
Lappin, MR	1
Black, JC	1
Knox, CM	1
Wong, IG	1
Love, P	1
Webber, SK	1
Lawless, MA	1
Sutton, GL	1
Rogers, CM	1
Wirostko, WJ	1
Connor, TB	1
Wagner, PF	1
Tandon, A	1
Tay-Kearney, ML	1
Metcalf, C	1
McAllister, L	1
Chang, MS	1
Lee, SS	1
Cunningham, ET	1
Suresh, PS	1
Herzig, S	1
Fukushima, H	1
Numaga, J	1
Yoshimoto, M	1
Kato, S	1
Kawashima, H	1
Macken, PL	1
Boyd, SR	1
Chang, D	1
Trope, GE	1
Ohadi, C	1
Litwin, KL	1
Moreira, H	1
Kwitko, S	1
Gauderman, WJ	1
Gritz, DC	1
Gwon, A	1
Jones, R	1
McDonnell, PJ	1
Hagenah, M	1
Insler, MS	1
Haimann, MH	1
Weiss, H	1
Miller, JA	1
Cohen, JI	1
Saragas, SJ	1
Heathcote, JG	1
McCartney, AC	1
Rice, NS	1
Peacock, J	1
Seal, DV	1
Seedor, JA	1
Koplin, RS	1
Shah, M	1
Almeda, EE	1
Perry, HD	1

Trial	Phase	Enrollment	Study Type	Start Date	Status
Use of Corticosteroids in Children Hospitalized With Cellulitis: Randomized, Double Blind, Placebo Controlled Trial[NCT02087527]		19 participants (Actual)	Interventional	2014-06-30	Terminated (stopped due to Calculated sample size not achieved)
Steroids for Corneal Ulcers Trial[NCT00324168]	Phase 4	500 participants (Actual)	Interventional	2006-09-30	Completed
Phase I/II Comparative Study of a Single Intraoperative Sub-Tenon's Capsule Injection of Triamcinolone and Ciprofloxacin in a Controlled-Release System Versus 1% Prednisolone and 0.3% Ciprofloxacin Eyedrops for Cataract Surgery[NCT00431028]	Phase 1/Phase 2	140 participants (Actual)	Interventional	2005-09-30	Terminated (stopped due to Terminated)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

LogMAR (logarithm of the Minimum Angle of Resolution) is a measure of visual acuity in which the smaller values indicate better visual acuity. (NCT00324168)
Timeframe: 3 months from enrollment

Best Spectacle-corrected Visual Acuity (BSCVA) in logMAR at 12 Months, Using Best Spectacle-corrected Enrollment Visual Acuity as a Co-variate

Intervention	logMAR (Mean)
Steroid	0.42
Placebo	0.41

LogMAR (logarithm of the Minimum Angle of Resolution) is a measure of visual acuity in which the smaller values indicate better visual acuity. (NCT00324168)
Timeframe: 12 months from enrollment

Best Spectacle-corrected Visual Acuity (BSCVA) in logMAR at 3 Months, Using Best Spectacle-corrected Enrollment Visual Acuity as a Co-variate

Intervention	logMAR (Mean)
Steroid	2.90
Placebo	2.87

LogMAR (logarithm of the Minimum Angle of Resolution) is a measure of visual acuity in which the smaller values indicate better visual acuity. (NCT00324168)
Timeframe: 3 months from enrollment

Best Spectacle-corrected Visual Acuity (BSCVA) in logMAR Using MIC (Minimum Inhibitory Concentration) to Moxifloxacin as a Covariate

Intervention	logMAR (Mean)
Steroid	0.48
Placebo	0.49

Best spectacle-corrected visual acuity (BSCVA) for this outcome is measured in logMAR (logarithm of the Minimum Angle of Resolution) in which smaller values indicate better visual acuity. Minimum inhibitory concentration (MIC) to moxifloxacin was measured by E test and a log2-transformation of MIC was used in all analyses. In this analysis we add MIC to the model examining BSCVA at 3 months. (NCT00324168)
Timeframe: 3 months after enrollment

Infiltrate/Scar Size, Correcting for Infiltrate/Scar Size at Enrollment

Ocular Perforations

Time to Resolution of Epithelial Defect

Intervention	logMAR (Mean)
Steroid	0.50
Placebo	0.46

Intervention	mm (Mean)
Steroid	3.07
Placebo	3.02

Intervention	participants (Number)
Steroid	7
Placebo	8

This outcome measured time from enrollment to resolution of the epithelial defect in days for up to 21 days. For three weeks patients were examined every 3 days for size of epithelial defect until the defect was gone. (NCT00324168)
Timeframe: From enrollment up to 21 days

Subgroup Analysis of Best Spectacle-corrected Visual Acuity (BSCVA) by Categories of Infiltrate Depth

Intervention	days (Mean)
Steroid	9.77
Placebo	9.43

BSCVA measured in logMAR will be examined by categories infiltrate depth (categorized by depth percentage) by mean and standard deviation as well as in a regression model. (NCT00324168)
Timeframe: 3 months from enrollment

Subgroup Analysis Predicting 3 Month Best Spectacle-corrected Visual Acuity (BSCVA) by Causative Organism

Intervention	logMAR (Mean)
	>0-33%	>33%-67%	>67%-100%
Placebo	0.26	0.47	0.86
Steroid	0.35	0.52	0.80

BSCVA measured in logMAR will be estimated by causative organism (either Nocardia spp, Streptococcus pneumoniae, Moraxella spp, or Pseudomonas aeruginosa). BSCVA will be examined for each causative organism by mean and standard deviation as well as in a regression model. (NCT00324168)
Timeframe: 3 months after enrollment

Subgroup Analysis Predicting 3 Month Best Spectacle-corrected Visual Acuity (BSCVA) by Visual Acuity Group

Intervention	logMAR (Mean)
	Nocardia spp	Streptococcus pneumoniae	Moraxella spp	Pseudomonas aeruginosa
Placebo	0.36	0.52	0.26	0.45
Steroid	0.54	0.49	0.46	0.53

Best spectacle-corrected visual acuity (BSCVA) for this subgroup analysis was measured in logMAR and then categorized by equivalent Snellen fractions (NCT00324168)
Timeframe: 3 months from enrollment

Subgroup Analysis Predicting Best Spectacle-corrected Visual Acuity (BSCVA) as Stratified by Categories of Infiltrate/Scar Size

Intervention	logMAR (Mean)
	<20/40	20/40 to 20/800	Counting fingers (CF) or worse
Placebo	-0.02	0.38	1.15
Steroid	0.06	0.36	1.00

Best-spectacle visual acuity (BSCVA) at 3 months from enrollment is stratified by categories of infiltrate/scar size and examined by treatment arm (NCT00324168)
Timeframe: 3 months from enrollment

Intervention	logMAR (Mean)
	0-1.90 mm	1.91-2.70 mm	2.71-4.06 mm	4.07-8.90 mm
Placebo	0.19	0.29	0.53	0.96
Steroid	0.18	0.39	0.53	0.85

Article	Year
Role of oral corticosteroids in orbital cellulitis. American journal of ophthalmology, 2013, Volume: 156, Issue:1 Topics: Administration, Oral; Adolescent; Adult; Anti-Bacterial Agents; Ceftriaxone; Child; Drug Therapy, Co	2013
Emerging moxifloxacin resistance in Pseudomonas aeruginosa keratitis isolates in South India. Ophthalmic epidemiology, 2013, Volume: 20, Issue:3 Topics: Anti-Bacterial Agents; Aza Compounds; Communicable Diseases, Emerging; Cornea; Corneal Ulcer; Double	2013
The steroids for corneal ulcers trial (SCUT): secondary 12-month clinical outcomes of a randomized controlled trial. American journal of ophthalmology, 2014, Volume: 157, Issue:2 Topics: Administration, Topical; Adult; Anti-Bacterial Agents; Aza Compounds; Bacteria; Corneal Ulcer; Doubl	2014
Visual recovery in treated bacterial keratitis. Ophthalmology, 2014, Volume: 121, Issue:6 Topics: Adult; Aged; Anti-Bacterial Agents; Aza Compounds; Corneal Ulcer; Eye Infections, Bacterial; Female;	2014
Visual outcomes in treated bacterial keratitis: four years of prospective follow-up. Investigative ophthalmology & visual science, 2014, May-02, Volume: 55, Issue:5 Topics: Adult; Aged; Anti-Bacterial Agents; Aza Compounds; Corneal Ulcer; Double-Blind Method; Eye Infection	2014
Early addition of topical corticosteroids in the treatment of bacterial keratitis. JAMA ophthalmology, 2014, Volume: 132, Issue:6 Topics: Administration, Topical; Adult; Aza Compounds; Confidence Intervals; Dose-Response Relationship, Dru	2014
Corticosteroids for bacterial corneal ulcers. The British journal of ophthalmology, 2009, Volume: 93, Issue:2 Topics: Adult; Aged; Corneal Ulcer; Double-Blind Method; Epithelium, Corneal; Eye Infections, Bacterial; Fea	2009
A single intraoperative sub-tenon's capsule injection of triamcinolone and ciprofloxacin in a controlled-release system for cataract surgery. Investigative ophthalmology & visual science, 2009, Volume: 50, Issue:7 Topics: Aged; Anterior Chamber; Anti-Infective Agents; Anti-Inflammatory Agents; Ciprofloxacin; Connective T	2009
The steroids for corneal ulcers trial: study design and baseline characteristics. Archives of ophthalmology (Chicago, Ill. : 1960), 2012, Volume: 130, Issue:2 Topics: Administration, Topical; Adult; Anti-Infective Agents; Aza Compounds; Bacteria; Cornea; Corneal Ulce	2012
Corticosteroids for bacterial keratitis: the Steroids for Corneal Ulcers Trial (SCUT). Archives of ophthalmology (Chicago, Ill. : 1960), 2012, Volume: 130, Issue:2 Topics: Administration, Topical; Adult; Anti-Infective Agents; Aza Compounds; Bacteria; Cornea; Corneal Ulce	2012
Pseudomonas aeruginosa keratitis: outcomes and response to corticosteroid treatment. Investigative ophthalmology & visual science, 2012, Jan-25, Volume: 53, Issue:1 Topics: Adult; Anti-Infective Agents; Aza Compounds; Corneal Ulcer; Double-Blind Method; Eye Infections, Bac	2012
Nocardia keratitis: clinical course and effect of corticosteroids. American journal of ophthalmology, 2012, Volume: 154, Issue:6 Topics: Administration, Topical; Adult; Anti-Infective Agents; Aza Compounds; Corneal Ulcer; Double-Blind Me	2012
Prior elicitation and Bayesian analysis of the Steroids for Corneal Ulcers Trial. Ophthalmic epidemiology, 2012, Volume: 19, Issue:6 Topics: Administration, Topical; Anti-Infective Agents; Aza Compounds; Bayes Theorem; Corneal Ulcer; Double-	2012
Fluoroquinolone treatment and susceptibility of isolates from bacterial keratitis. JAMA ophthalmology, 2013, Volume: 131, Issue:3 Topics: Adult; Anti-Bacterial Agents; Aza Compounds; Bacteria; Corneal Ulcer; Double-Blind Method; Drug Resi	2013
Moxifloxacin susceptibility mediates the relationship between causative organism and clinical outcome in bacterial keratitis. Investigative ophthalmology & visual science, 2013, Feb-28, Volume: 54, Issue:2 Topics: Administration, Topical; Anti-Infective Agents; Aza Compounds; Bacteria; Corneal Ulcer; Disease Susc	2013
Microbial keratitis in prospective studies of extended wear with disposable hydrogel contact lenses. Cornea, 2005, Volume: 24, Issue:2 Topics: Adolescent; Adult; Anti-Infective Agents; Bacteria; Ciprofloxacin; Contact Lenses, Extended-Wear; Co	2005
Does in vitro susceptibility predict clinical outcome in bacterial keratitis? American journal of ophthalmology, 2008, Volume: 145, Issue:3 Topics: Anti-Infective Agents; Aza Compounds; Bacteria; Corneal Ulcer; Disease Susceptibility; Eye Infection	2008

Article	Year
Diffuse Phlebitis in Patients with Syphilitic Outer Retinopathy. Ocular immunology and inflammation, 2021, Nov-17, Volume: 29, Issue:7-8 Topics: Adult; Anti-Bacterial Agents; Ceftriaxone; Doxycycline; Electroretinography; Eye Infections, Bacteri	2021
Chorioretinal Lesions and Symptoms of Elevated Intracranial Pressure. JAMA ophthalmology, 2017, 08-01, Volume: 135, Issue:8 Topics: Acute Disease; Administration, Oral; Adult; Anti-Bacterial Agents; Antiretroviral Therapy, Highly Ac	2017
Blurry Vision and Eye Pain After Pterygium Surgery. JAMA ophthalmology, 2018, 07-01, Volume: 136, Issue:7 Topics: Administration, Oral; Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Eye Infe	2018
Impact of topical corticosteroid pretreatment on susceptibility of the injured murine cornea to Pseudomonas aeruginosa colonization and infection. Experimental eye research, 2019, Volume: 179 Topics: Administration, Ophthalmic; Animals; Cornea; Corneal Injuries; Corneal Ulcer; Disease Models, Animal	2019
Endogenous bacterial endophthalmitis caused by Pantoea species: a case report. Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2014, Volume: 49, Issue:1 Topics: Administration, Topical; Anti-Bacterial Agents; Bacteremia; Drug Therapy, Combination; Endophthalmit	2014
Klebsiella Endophthalmitis as Retinal Vasculitis with Prostatic Abscess. Optometry and vision science : official publication of the American Academy of Optometry, 2015, Volume: 92, Issue:7 Topics: Abscess; Anti-Bacterial Agents; Ceftazidime; Drug Therapy, Combination; Endophthalmitis; Eye Infecti	2015
Acute Mycoplasma pneumoniae infection presenting with unilateral anterior uveitis and perineuritis. Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2016, Volume: 20, Issue:2 Topics: Acute Disease; Adolescent; Eye Infections, Bacterial; Female; Glucocorticoids; Humans; Magnetic Reso	2016
Hemorrhagic Descemet Membrane Detachment Following Syphilitic Interstitial Keratitis. Cornea, 2016, Volume: 35, Issue:9 Topics: Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents; Chloramphenicol; Combined Modality Therapy; C	2016
Mycobacterium abscessus scleritis after a Baerveldt glaucoma implant. Clinical & experimental ophthalmology, 2017, Volume: 45, Issue:3 Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Ceftazidime; Chronic Disease; Drug Therapy, Combina	2017
Brucellosis and uveitis. Annals of ophthalmology (Skokie, Ill.), 2008,Spring, Volume: 40, Issue:1 Topics: Adult; Agglutination Tests; Brucellosis; Child; Coombs Test; Doxycycline; Drug Therapy, Combination;	2008
Culture-positive endophthalmitis after implantation of intraocular Collamer lens. Journal of cataract and refractive surgery, 2009, Volume: 35, Issue:10 Topics: Adult; Anti-Bacterial Agents; Drug Therapy, Combination; Endophthalmitis; Eye Infections, Bacterial;	2009
VIP promotes resistance in the Pseudomonas aeruginosa-infected cornea by modulating adhesion molecule expression. Investigative ophthalmology & visual science, 2010, Volume: 51, Issue:11 Topics: Animals; Cell Adhesion Molecules; Cell Movement; Corneal Ulcer; Disease Models, Animal; Enzyme-Linke	2010
The effectiveness of an improved combination therapy for experimental Staphylococcus aureus keratitis. Advances in therapy, 2010, Volume: 27, Issue:12 Topics: Animals; Anti-Bacterial Agents; Colony Count, Microbial; Cornea; Dexamethasone; Disease Models, Anim	2010
Peripapillary choroidal neovascularisation in the context of ocular syphilis is sensitive to combination antibiotic and corticosteroid treatment. International ophthalmology, 2013, Volume: 33, Issue:2 Topics: Anti-Bacterial Agents; Choroidal Neovascularization; Drug Therapy, Combination; Eye Infections, Bact	2013
Improvement in corneal scarring following bacterial keratitis. Eye (London, England), 2013, Volume: 27, Issue:3 Topics: Adult; Aged; Aza Compounds; Cicatrix; Corneal Ulcer; Eye Infections, Bacterial; Female; Fluoroquinol	2013
A comparison of invasive and cytotoxic Pseudomonas aeruginosa strain-induced corneal disease responses to therapeutics. Current eye research, 2003, Volume: 27, Issue:5 Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Cornea; Corneal Ulcer; Disease Models, Anim	2003
Bilateral severe visual loss in brucellosis. Ocular immunology and inflammation, 2004, Volume: 12, Issue:3 Topics: Adult; Anti-Bacterial Agents; Antibodies, Bacterial; Brucella; Brucellosis; Doxycycline; Drug Therap	2004
Adult-onset syphilitic stromal keratitis. American journal of ophthalmology, 2006, Volume: 141, Issue:2 Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Corneal Stroma; Eye Infections, Bacterial;	2006
Secondary bacterial keratitis associated with shield ulcer caused by vernal conjunctivitis. Cornea, 2006, Volume: 25, Issue:8 Topics: Anti-Bacterial Agents; Cefazolin; Child; Conjunctivitis, Allergic; Corneal Ulcer; Cyclopentolate; Dr	2006
Posttraumatic Stenotrophomonas maltophilia infectious scleritis. Cornea, 2008, Volume: 27, Issue:2 Topics: Ciprofloxacin; Combined Modality Therapy; Conjunctiva; Drug Therapy, Combination; Eye Foreign Bodies	2008
Phlyctenular keratoconjunctivitis in a patient with Staphylococcal blepharitis and ocular rosacea. Optometry (St. Louis, Mo.), 2008, Volume: 79, Issue:3 Topics: Administration, Oral; Administration, Topical; Adult; Aza Compounds; Blepharitis; Cyclosporine; Doxy	2008
Infectious crystalline keratopathy following trabeculectomy and low-dose topical steroids. Cornea, 1995, Volume: 14, Issue:3 Topics: Administration, Topical; Aged; Anti-Bacterial Agents; Cornea; Corneal Opacity; Diabetes Mellitus, Ty	1995
Ocular leprosy: do steroids complicate matters? International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1995, Volume: 63, Issue:1 Topics: Administration, Oral; Adult; Cataract; Endophthalmitis; Eye Infections, Bacterial; Humans; Leprosy,	1995
Effectiveness of specific antibiotic/steroid combinations for therapy of experimental Pseudomonas aeruginosa keratitis. Current eye research, 1995, Volume: 14, Issue:3 Topics: Animals; Anti-Bacterial Agents; Ciprofloxacin; Colony Count, Microbial; Cornea; Dexamethasone; Disea	1995
Characterization of the inflammatory response induced by corneal infection with Pseudomonas aeruginosa. Journal of ocular pharmacology, 1994,Spring, Volume: 10, Issue:1 Topics: Animals; Colony Count, Microbial; Cytokines; Dinoprostone; Eye Infections, Bacterial; Keratitis; Mic	1994
Bilateral optic neuropathy and white dot syndrome following a mycoplasmal infection. The British journal of ophthalmology, 1993, Volume: 77, Issue:10 Topics: Erythromycin; Eye Infections, Bacterial; Female; Fluorescein Angiography; Humans; Middle Aged; Mycop	1993
Prednisolone acetate or prednisolone phosphate concurrently administered with ciprofloxacin for the therapy of experimental Pseudomonas aeruginosa keratitis. Current eye research, 1993, Volume: 12, Issue:5 Topics: Animals; Aqueous Humor; Ciprofloxacin; Corneal Ulcer; Disease Models, Animal; Drug Therapy, Combinat	1993
Endophthalmitis associated with microbial keratitis. Ophthalmology, 1996, Volume: 103, Issue:11 Topics: Anti-Inflammatory Agents; Bacteria; Corneal Ulcer; Endophthalmitis; Eye Infections, Bacterial; Eye I	1996
Recurrent anterior uveitis associated with streptococcal pharyngitis in a patient with a history of poststreptococcal syndrome. American journal of ophthalmology, 1999, Volume: 127, Issue:3 Topics: Adolescent; Eye Infections, Bacterial; Female; Follow-Up Studies; Humans; Pharyngitis; Prednisolone;	1999
Bartonella spp infection as a possible cause of uveitis in a cat. Journal of the American Veterinary Medical Association, 1999, Apr-15, Volume: 214, Issue:8 Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antibodies, Bacteria	1999
Chronic uveitis following a streptococcal illness. Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1999, Volume: 34, Issue:2 Topics: Chronic Disease; Eye Infections, Bacterial; Glucocorticoids; Humans; Male; Methotrexate; Middle Aged	1999
Staphylococcal infection under a LASIK flap. Cornea, 1999, Volume: 18, Issue:3 Topics: Abscess; Adult; Anti-Bacterial Agents; Corneal Diseases; Corneal Transplantation; Debridement; Drug	1999
Recurrent poststreptococcal uveitis. Archives of ophthalmology (Chicago, Ill. : 1960), 1999, Volume: 117, Issue:12 Topics: Child; Eye Infections, Bacterial; Humans; Male; Mydriatics; Pharyngitis; Photophobia; Prednisolone;	1999
Bacillus circulans endophthalmitis. Clinical & experimental ophthalmology, 2001, Volume: 29, Issue:2 Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Bacillaceae Infections; Bacillus; Cephalosporins; Ce	2001
Focal retinal phlebitis as a presenting sign of systemic Bartonella henselae infection. Retina (Philadelphia, Pa.), 2001, Volume: 21, Issue:3 Topics: Anti-Bacterial Agents; Antibodies, Bacterial; Bartonella henselae; Cat-Scratch Disease; Doxycycline;	2001
Mycobacterium keratitis following hyperopic laser in situ keratomileusis. Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2001, Volume: 36, Issue:5 Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Cornea; Drug Resistance, Microbial; Drug Therapy, C	2001
An ocular cat-scratch disease patient positive for cytoplasmic anti-neutrophil cytoplasmic antibody. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2001, Volume: 239, Issue:11 Topics: Ampicillin; Antibodies, Antineutrophil Cytoplasmic; Biomarkers; Cat-Scratch Disease; Drug Therapy, C	2001
Haemophilus aphrophilus bleb infection after a mitomycin trabeculectomy. Australian and New Zealand journal of ophthalmology, 1995, Volume: 23, Issue:4 Topics: Anti-Bacterial Agents; Drug Therapy, Combination; Eye Infections, Bacterial; Female; Glaucoma; Gluco	1995
Anti-inflammatory therapy and outcome in a guinea pig model of Pseudomonas keratitis. Cornea, 1992, Volume: 11, Issue:5 Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dicarboxylic Acids; Disease	1992
Ciprofloxacin and prednisolone therapy for experimental Pseudomonas keratitis. Current eye research, 1992, Volume: 11, Issue:3 Topics: Administration, Topical; Animals; Ciprofloxacin; Colony Count, Microbial; Corneal Stroma; Disease Mo	1992
Delayed-onset pseudophakic endophthalmitis. American journal of ophthalmology, 1991, May-15, Volume: 111, Issue:5 Topics: Cataract Extraction; Endophthalmitis; Eye Infections, Bacterial; Humans; Lenses, Intraocular; Predni	1991
Endophthalmitis due to Mycobacterium avium in a patient with AIDS. Annals of ophthalmology, 1990, Volume: 22, Issue:2 Topics: Acquired Immunodeficiency Syndrome; Adult; Anterior Chamber; Cefazolin; Endophthalmitis; Eye Infecti	1990
Endophthalmitis caused by exogenous nocardial infection in a patient with Sjögren's syndrome. Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1990, Volume: 25, Issue:1 Topics: Chloramphenicol; Corneal Diseases; Endophthalmitis; Eye Enucleation; Eye Infections, Bacterial; Fema	1990
Chronic postoperative endophthalmitis from Staphylococcus aureus. Journal of cataract and refractive surgery, 1990, Volume: 16, Issue:4 Topics: Aqueous Humor; Cefazolin; Chronic Disease; Endophthalmitis; Eye Infections, Bacterial; Female; Human	1990

prednisolone and Bacterial Eye Infections