Page last updated: 2024-11-06

prednisolone and B16 Melanoma

prednisolone has been researched along with B16 Melanoma in 11 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Research Excerpts

ExcerptRelevanceReference
"Tumor-associated inflammation has been recognized as an important tumor growth propagator and, therefore, represents an attractive target for anti-cancer therapy."1.37Anti-tumor activity of liposomal glucocorticoids: The relevance of liposome-mediated drug delivery, intratumoral localization and systemic activity. ( Boekhoven, RW; Kluza, E; Nicolay, K; Schiffelers, RM; Schmid, S; Storm, G; Strijkers, GJ; van der Schaft, DW; Yeo, SY, 2011)
" The antitumor effects of the free drugs have only been observed using treatment schedules based on high and frequent dosing for prolonged periods of time."1.33Liposome-encapsulated prednisolone phosphate inhibits growth of established tumors in mice. ( Fens, MH; Janssen, AP; Metselaar, JM; Molema, G; Schiffelers, RM; Storm, G, 2005)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's5 (45.45)29.6817
2010's4 (36.36)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Licarete, E2
Rauca, VF2
Luput, L2
Patras, L2
Sesarman, A2
Banciu, M6
Drotar, D1
Stejerean, I1
Dume, B1
Toma, VA1
Porfire, A1
Gherman, C1
Smits, EAW1
Soetekouw, JA1
Pieters, EHE1
Smits, CJP1
de Wijs-Rot, N1
Vromans, H1
Metselaar, JM4
Schiffelers, RM6
Storm, G7
Kluza, E1
Yeo, SY1
Schmid, S1
van der Schaft, DW1
Boekhoven, RW1
Strijkers, GJ1
Nicolay, K1
Cittadino, E1
Ferraretto, M1
Torres, E1
Maiocchi, A1
Crielaard, BJ1
Lammers, T1
Aime, S1
Terreno, E1
Fens, MH3
Janssen, AP1
Molema, G1
Musch, E1
Malek, M1
Peter-Katalinic, J1
Egge, H1
Rink, H1
Lathan, B1
Riedel, E1

Other Studies

11 other studies available for prednisolone and B16 Melanoma

ArticleYear
The prednisolone phosphate‑induced suppression of the angiogenic function of tumor‑associated macrophages enhances the antitumor effects of doxorubicin on B16.F10 murine melanoma cells in vitro.
    Oncology reports, 2019, Volume: 42, Issue:6

    Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Doxorubicin; Drug

2019
Overcoming Intrinsic Doxorubicin Resistance in Melanoma by Anti-Angiogenic and Anti-Metastatic Effects of Liposomal Prednisolone Phosphate on Tumor Microenvironment.
    International journal of molecular sciences, 2020, Apr-23, Volume: 21, Issue:8

    Topics: Animals; Antineoplastic Agents; Biomarkers; Cell Line, Tumor; Doxorubicin; Liposomes; Macrophages; M

2020
The availability of drug by liposomal drug delivery : Individual kinetics and tissue distribution of encapsulated and released drug in mice after administration of PEGylated liposomal prednisolone phosphate.
    Investigational new drugs, 2019, Volume: 37, Issue:5

    Topics: Animals; Apoptosis; Cell Proliferation; Disease Models, Animal; Drug Delivery Systems; Drug Liberati

2019
Liposomal glucocorticoids as tumor-targeted anti-angiogenic nanomedicine in B16 melanoma-bearing mice.
    The Journal of steroid biochemistry and molecular biology, 2008, Volume: 111, Issue:1-2

    Topics: Animals; Budesonide; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cells, Cultured; Colonic N

2008
Anti-tumor activity of liposomal glucocorticoids: The relevance of liposome-mediated drug delivery, intratumoral localization and systemic activity.
    Journal of controlled release : official journal of the Controlled Release Society, 2011, Apr-10, Volume: 151, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Cell Line, Tumor; Glucocorticoids; Humans;

2011
MRI evaluation of the antitumor activity of paramagnetic liposomes loaded with prednisolone phosphate.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2012, Mar-12, Volume: 45, Issue:4

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Contrast Media; Gadolinium; Glucocorticoids; Lipos

2012
Liposome-encapsulated prednisolone phosphate inhibits growth of established tumors in mice.
    Neoplasia (New York, N.Y.), 2005, Volume: 7, Issue:2

    Topics: Animals; Cell Proliferation; Colonic Neoplasms; Endothelial Cells; Liposomes; Male; Melanoma, Experi

2005
Anti-angiogenic effects of liposomal prednisolone phosphate on B16 melanoma in mice.
    Journal of controlled release : official journal of the Controlled Release Society, 2006, Jun-12, Volume: 113, Issue:1

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cells, Cultured; Colonic Neoplasms; Dr

2006
Antitumor activity of liposomal prednisolone phosphate depends on the presence of functional tumor-associated macrophages in tumor tissue.
    Neoplasia (New York, N.Y.), 2008, Volume: 10, Issue:2

    Topics: Animals; Antineoplastic Agents; Clodronic Acid; Liposomes; Macrophages; Male; Melanoma, Experimental

2008
Antitumor activity and tumor localization of liposomal glucocorticoids in B16 melanoma-bearing mice.
    Journal of controlled release : official journal of the Controlled Release Society, 2008, Apr-21, Volume: 127, Issue:2

    Topics: Animals; Antineoplastic Agents; Budesonide; Dexamethasone; Dose-Response Relationship, Drug; Liposom

2008
Cellular kinetics of prednimustine versus chlorambucil plus prednisolone in vitro.
    Cancer chemotherapy and pharmacology, 1992, Volume: 29, Issue:4

    Topics: Animals; Carcinoma; Chlorambucil; Chromatography, High Pressure Liquid; Colonic Neoplasms; Mammary N

1992