Page last updated: 2024-11-06

prednisolone and B-Cell Chronic Lymphocytic Leukemia

prednisolone has been researched along with B-Cell Chronic Lymphocytic Leukemia in 80 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Research Excerpts

ExcerptRelevanceReference
" We experienced a case of non-chronic lymphocytic leukemia type monoclonal B-cell lymphocytosis (MBL) that was exacerbated by increasing prednisolone for dermatomyositis and then improved by decreasing the dosage."8.02Monoclonal B-cell Lymphocytosis Exacerbated by Prednisolone Therapy for Dermatomyositis. ( Hayashi, K; Kashiwakuma, D; Kubodera, A; Kume, A; Shimizu, R; Suzuki, Y; Tanaka, H, 2021)
" He was diagnosed as having fibrinoid syndrome and started on topical prednisolone, brimonidine, timolol-dorzolamide, and orally administered acetazolamide."4.98Anterior chamber fibrinoid syndrome after cataract extraction in a patient on ibrutinib for B-cell chronic lymphocytic leukemia: a case report and review of the literature. ( Hwang, CK; Kim, BJ; Kolomeyer, AM, 2018)
" We experienced a case of non-chronic lymphocytic leukemia type monoclonal B-cell lymphocytosis (MBL) that was exacerbated by increasing prednisolone for dermatomyositis and then improved by decreasing the dosage."4.02Monoclonal B-cell Lymphocytosis Exacerbated by Prednisolone Therapy for Dermatomyositis. ( Hayashi, K; Kashiwakuma, D; Kubodera, A; Kume, A; Shimizu, R; Suzuki, Y; Tanaka, H, 2021)
" He was diagnosed with type I cryoglobulinemia and treated with rituximab, plasmapheresis, methylprednisolone, and ibrutinib was restarted."3.91Cryoglobulinemic vasculitis with interruption of ibrutinib therapy for chronic lymphocytic leukemia (CLL). ( Field, J; George, G; Singavi, A; Voshtina, E; Wright, N, 2019)
" Evans syndrome had been diagnosed and daily prednisolone therapy had been performed."3.68[Chronic lymphocytic leukemia diagnosed after corticosteroid therapy for Evans syndrome]. ( Iriuchijima, T; Matsuzaki, T; Mori, M; Murakami, H; Naruse, T; Shimizu, H; Tomioka, M; Yuasa, K, 1992)
"Of 79 evaluable patients, 58 (73%) had follicular lymphoma, 13 (16%) mantle cell lymphoma and 8 (10%) lymphoplasmacytic lymphoma."2.73Initial chemotherapy with mitoxantrone, chlorambucil, prednisone impairs the collection of stem cells in patients with indolent lymphomas--results of a randomized comparison by the German Low-Grade Lymphoma Study Group. ( Dörken, B; Dreyling, M; Forstpointner, R; Freund, M; Ganser, A; Hiddemann, W; Hoster, E; Huber, C; Ludwig, WD; Nickenig, C; Trümper, L; Unterhalt, M, 2007)
"There was no association of infections or febrile episodes with the use of corticosteroids or the CD4 count at the end of treatment and a poor correlation with the increase in CD4 counts during remission."2.69Long-term follow-up of patients with chronic lymphocytic leukemia (CLL) receiving fludarabine regimens as initial therapy. ( Beran, M; Estey, E; Freireich, EJ; Kantarjian, H; Keating, MJ; Koller, C; Lerner, S; O'Brien, S; Robertson, LE, 1998)
"The ratio of minimal residual disease was 0."1.38[Detection and impact of minimal residual disease on outcome of chronic lymphocytic leukemia]. ( Bozsó, T; Iványi, JL; Plander, M; Skrapits, J; Szendrei, T, 2012)
"Bendamustine is a safe and useful addition to the drug arsenal against lymphoproliferative disorders."1.37Preliminary experience with the use of bendamustine: a peculiar skin rash as the commonest side effect. ( Ganesan, P; Malipatil, B; Sagar, TG; Sundersingh, S, 2011)
"Although renal failure due to leukemic infiltration has been described in many cases of acute leukemia, only 11 cases of renal failure due to CLL cells' infiltration have been described in the literature."1.36Renal dysfunction due to leukemic infiltration of kidneys in a case of chronic lymphocytic leukemia. ( Brum, S; Carvalho, D; Carvalho, F; Ferreira, AC; Pataca, I; Santos, JR; Santos, MC, 2010)
"Paraneoplastic pemphigus is a rare autoimmune disease characterized by polymorphous mucocutaneous lesions in association with underlying neoplasia."1.36Paraneoplastic pemphigus characterized by polymorphic oral mucosal manifestations--report of two cases. ( Gao, Y; Hua, H; Yan, Z, 2010)
"Daunorubicin was the most potent drug."1.36Chronic lymphoid leukemia cells are highly sensitive to the combination of prednisolone and daunorubicin, but much less to doxorubicin or epirubicin. ( Adam, E; Eksborg, S; Flaberg, E; Klein, E; Kozma, A; Markasz, L; Masszi, T; Miseta, A; Nagy, N; Otvos, R; Skribek, H; Szekely, L, 2010)
"Fifty-two cases of autoimmune hemolytic anemia (AHA) were observed within a series of 1203 patients (4."1.31Autoimmune hemolytic anemia in chronic lymphocytic leukemia: clinical, therapeutic, and prognostic features. ( Cerretti, R; Coluzzi, S; Foa, R; Giannarelli, D; Girelli, G; Mandelli, F; Mauro, FR, 2000)
"Verapamil cytotoxicity was investigated in peripheral blood samples of 35 patients with B-cell CLL and 10 healthy control subjects."1.31Calcium antagonists potentiate P-glycoprotein-independent anticancer drugs in chronic lymphocytic leukemia cells in vitro. ( Koski, T; Vilpo, J; Vilpo, L, 2000)
"In patients with chronic lymphocytic leukemia (CLL), TK levels may provide prognostic information independent of stage and other prognostic factors, but it is still unclear whether they can be used to predict the response to treatment and length of survival."1.31Retrospective study of the prognostic role of serum thymidine kinase level in CLL patients with active disease treated with fludarabine. ( Cacciola, E; Di Raimondo, F; Giustolisi, R; Kantarjian, H; Keating, MJ; Lerner, S; O'Brien, S, 2001)
"Muscle contraction was easily elicited by percussion, which was visible from the surface and propagated in a rolling manner."1.31Rippling muscle syndrome preceding malignant lymphoma. ( Ida, M; Kawagoe, S; Kojima, S; Takagi, A; Watanabe, T, 2002)
"There is a spectrum of types of MPGN seen in patients with CLL and there appears to be an association with the presence of monoclonal gammopathy."1.31Membranoproliferative glomerulonephritis in association with chronic lymphocytic leukaemia: a report of three cases. ( Dwyer, KM; Firkin, F; Hill, PA; Lee, P; Murphy, BF, 2002)
"We describe a B cell chronic lymphocytic leukemia/lymphoma (B-CLL) patient with an adrenocortical adenoma."1.30Functional adrenocortical adenoma in a case with B cell chronic lymphoproliferative disorder. ( Adachi, M; Adachi, Y; Fukushima, H; Hinoda, Y; Imai, K; Takahashi, T, 1997)
"Treatment with chlorambucil, prednisolone, and renal bed irradiation resulted in a substantial improvement in renal function which persisted until the the patient's death from marrow failure some eight years later."1.29Renal failure caused by leukaemic infiltration in chronic lymphocytic leukaemia. ( Bass, PS; Davies, DR; Jones, NF; Majumdar, G; Pearson, TC; Phillips, JK, 1993)
"B-cell chronic lymphocytic leukemia (B-CLL) associated with bone marrow fibrosis is described."1.29Chronic lymphocytic leukemia associated with bone marrow fibrosis: possible role of interleukin 1 alpha in the pathogenesis. ( Hyodo, H; Kimura, A; Kuramoto, A; Nakata, Y, 1993)
"We report a case of B-cell chronic lymphocytic leukemia in a 58 year old female in whom the clinical course was dominated by upper airway obstruction due to massive enlargement of the palatine and later the lingual tonsils."1.29Chronic lymphocytic leukaemia with upper airway obstruction. ( Cole, I; Cunningham, I; Dao, LP; Dean, MG; Mulligan S, P, 1996)
"Although many cases of Waldenström's macroglobulinemia (WMG) with pulmonary involvement have been reported, endobronchial involvement has not been described."1.28Endobronchial involvement with Waldenström's macroglobulinemia. ( Kanegae, H; Matumoto, I; Sakai, I; Shiroguchi, T, 1992)

Research

Studies (80)

TimeframeStudies, this research(%)All Research%
pre-19904 (5.00)18.7374
1990's22 (27.50)18.2507
2000's27 (33.75)29.6817
2010's24 (30.00)24.3611
2020's3 (3.75)2.80

Authors

AuthorsStudies
Wright, N1
Voshtina, E1
George, G1
Singavi, A1
Field, J1
Thermos, G1
Tosios, KI1
Inatsu, E1
Fujii, K1
Hatanaka, M1
Okubo, A1
Uchida, Y1
Higashi, Y1
Hiraki, T1
Tanimoto, A1
Kanekura, T1
Kume, A1
Kashiwakuma, D1
Kubodera, A1
Hayashi, K1
Shimizu, R1
Suzuki, Y2
Tanaka, H1
Tsertsvadze, T1
Mitskevich, N1
Bilanishvili, A1
Girdaladze, D1
Porakishvili, N1
Sajawal, S1
Mackie, SL1
Hillmen, P1
McGonagle, D1
Koya, J1
Ebisawa, K1
Abe, H1
Shinozaki-Ushiku, A1
Nakamura, F1
Kurokawa, M1
Kolomeyer, AM1
Hwang, CK1
Kim, BJ1
Sylvan, SE1
Asklid, A1
Johansson, H1
Klintman, J1
Bjellvi, J1
Tolvgård, S1
Kimby, E1
Norin, S1
Andersson, PO1
Karlsson, C1
Karlsson, K1
Lauri, B1
Mattsson, M1
Sandstedt, AB1
Strandberg, M1
Österborg, A1
Hansson, L1
Scala, C1
Ortiz, K1
Nicolier, A1
Briend-Marchal, A1
Kiratli, H1
Tarlan, B1
Uzun, S1
Tanas, Ö1
Uner, A1
Dharmshaktu, P1
Gupta, N1
Dhanwal, DK1
Katagiri, S1
Yoshizawa, S1
Gotoh, M1
Nakamura, I1
Ohyashiki, K1
Cramer, P1
Isfort, S1
Bahlo, J1
Stilgenbauer, S1
Döhner, H1
Bergmann, M1
Stauch, M1
Kneba, M1
Lange, E1
Langerbeins, P1
Pflug, N1
Kovacs, G1
Goede, V1
Fink, AM1
Elter, T1
Fischer, K1
Wendtner, CM1
Hallek, M1
Eichhorst, B1
Del Principe, MI1
Dal Bo, M1
Bittolo, T1
Buccisano, F1
Rossi, FM1
Zucchetto, A1
Rossi, D1
Bomben, R1
Maurillo, L1
Cefalo, M1
De Santis, G1
Venditti, A1
Gaidano, G1
Amadori, S1
de Fabritiis, P1
Gattei, V1
Del Poeta, G1
Jayasekera, PS1
Bakshi, A1
Al-Sharqi, A1
Lim, SM1
Jang, JW1
Kim, BW1
Choi, H1
Choi, KY1
Park, SJ1
Han, CW1
Lindhagen, E2
Norberg, M1
Kanduri, M1
Tobin, G2
Säisänen, L1
Aberg, M1
Gustafsson, MG1
Sundström, C2
Rosenquist, R2
Aleskog, A2
Ferreira, AC1
Brum, S1
Carvalho, D1
Pataca, I1
Carvalho, F1
Santos, MC1
Santos, JR1
Namdar, T1
Mailänder, P1
Lange, T1
Anoop, P1
Stanford, M1
Saso, R1
Dearden, CE1
Graves, TD1
Collins, GP1
Parry, A1
Yan, Z1
Hua, H1
Gao, Y1
Skribek, H1
Otvos, R1
Flaberg, E1
Nagy, N1
Markasz, L1
Eksborg, S1
Masszi, T1
Kozma, A1
Adam, E1
Miseta, A1
Klein, E1
Szekely, L1
Sillito, F1
Cervi, P2
Skibinska, M1
Tadmor, T1
Bejar, J1
Attias, D1
Polliack, A1
Malipatil, B1
Ganesan, P1
Sundersingh, S1
Sagar, TG1
Krejci, M1
Doubek, M1
Brychtova, Y1
Stehlikova, O1
Chovancova, J1
Tichy, B1
Francova, HS1
Navratil, M1
Tomiska, M1
Horky, O1
Pospisilova, S1
Mayer, J1
Plander, M1
Skrapits, J1
Bozsó, T1
Szendrei, T1
Iványi, JL1
McCurdy, O1
McCormack, C1
Ritchie, D1
Prince, HM1
Brown, SJ1
Barrett, PD1
Hendrick, A1
Langtry, JA1
Aktan, M1
Akkaya, A1
Doğan, O1
Dincol, G1
BRUNNER, K1
KEISER, G1
MARTZ, G1
SCHREK, R1
Fujino, Y1
Sawamura, S1
Kurakawa, N1
Hisasue, M1
Masuda, K1
Ohno, K1
Tsujimoto, H1
Laurell, A1
Thunberg, U1
Roos, G1
Nilsson, K1
Nygren, P1
Höglund, M1
Larsson, R1
Ayyildiz, O1
Isikdogan, A1
Bolaman, Z1
Muftuoglu, E1
Narayan, H1
Bandyopadhyay, D1
Schmidt, K1
Chachlani, N1
Hughes, M1
Paneesha, S1
Rose, P1
Borg, A1
Nishida, H1
Murase, T1
Ueno, H2
Park, JW1
Yano, T1
Ikeda, Y1
Hanamura, A1
Hayakawa, M1
Naito, K1
Nickenig, C1
Dreyling, M1
Hoster, E1
Ludwig, WD1
Dörken, B1
Freund, M1
Huber, C1
Ganser, A1
Trümper, L1
Forstpointner, R1
Unterhalt, M1
Hiddemann, W1
Nanda, M1
Nanda, A1
Al-Sabah, H1
Dvorak, R1
Alsaleh, QA1
Helbling, I1
Walewska, R1
Dyer, MJ1
Bamford, M1
Harman, KE1
Smolej, L1
Hasselbach, HC1
Fickenscher, H1
Nölle, B1
Roider, J1
Lavabre-Bertrand, T1
Exbrayat, C1
Bourquard, P1
Lavabre-Bertrand, C1
Fégueux, N1
Poncelet, P1
Rousset, T1
Taïb, J1
Emberger, JM1
Navarro, M1
Bosanquet, AG2
McCann, SR1
Crotty, GM1
Mills, MJ2
Catovsky, D1
Hirano, T1
Tomiyoshi, K1
Take, H1
Watanabe, N1
Oriuchi, N1
Inoue, T1
Naruse, M1
Endo, K1
Phillips, JK1
Bass, PS1
Majumdar, G2
Davies, DR1
Jones, NF1
Pearson, TC1
Kimura, A1
Hyodo, H1
Nakata, Y1
Kuramoto, A1
Taillan, B1
Garnier, G1
Heudier, P1
Pesce, A1
Fuzibet, JG1
Dujardin, P1
Ando, S2
Otani, N1
Kanbe, T1
Brown, S1
Slater, NG1
Singh, AK1
Hattenhauer, MG1
Pach, JM1
Dean, MG1
Cunningham, I1
Dao, LP1
Cole, I1
Mulligan S, P1
Ruskoné-Fourmestraux, A1
Delmer, A1
Lavergne, A1
Molina, T1
Brousse, N1
Audouin, J1
Rambaud, JC1
Levin, M1
Aziz, M1
Opitz, L1
Adachi, Y1
Adachi, M1
Hinoda, Y1
Fukushima, H1
Takahashi, T1
Imai, K1
Yokose, N1
Ogata, K1
Nakamura, K1
Kamikubo, K1
Tamura, H1
An, E1
Dan, K1
Nomura, T1
Drake, WM1
Monson, JP1
Trainer, PJ1
Sharief, M1
Dick, JP1
Kelsey, SM2
Keating, MJ2
O'Brien, S2
Lerner, S2
Koller, C1
Beran, M1
Robertson, LE1
Freireich, EJ1
Estey, E1
Kantarjian, H2
Bosanquet, MI1
Takahashi, F1
Ogawa, Y1
Hasebe, N1
Natori, S1
Tokusashi, Y1
Miyokawa, N1
Kikuchi, K1
Mauro, FR1
Foa, R1
Cerretti, R1
Giannarelli, D1
Coluzzi, S1
Mandelli, F1
Girelli, G1
Várkonyi, J1
Zalatnai, A1
Timár, J1
Matolcsi, A1
Falus, A1
Bencsáth, M1
László, V1
Pócsik, E1
Kotlán, B1
Császár, A1
Vilpo, J1
Koski, T1
Vilpo, L1
Hall, RL1
Leahy, MF1
Cobcroft, R1
Di Raimondo, F1
Giustolisi, R1
Cacciola, E1
McBride, NC1
Cavenagh, JD1
Ward, MC1
Grant, I1
Schey, S1
Gray, A1
Hughes, A1
Newland, AC1
Takagi, A1
Kojima, S1
Watanabe, T1
Ida, M1
Kawagoe, S1
Hill, PA1
Firkin, F1
Dwyer, KM1
Lee, P1
Murphy, BF1
Sakai, I1
Shiroguchi, T1
Kanegae, H1
Matumoto, I1
Tomioka, M1
Shimizu, H1
Matsuzaki, T1
Yuasa, K1
Iriuchijima, T1
Mori, M1
Murakami, H1
Naruse, T1
Murphy, JA1
Pitts, JF1
Dudgeon, J1
Hogg, RB1
Harnett, AN1
Muraoka, A1
Asami, M1
Yoneda, R1
Ogura, M1
Oribe, T1
Suzuki, K1
Maeda, M1
Chinzei, T1
Yamashiro, K1
Ijichi, S1
Sano, Y1
Une, F1
Maruyama, I1
Osame, M1
Weiss, C1
Ho, AD1
Hiller, E1
Thiel, E1
Schlag, R1
Lipp, T1
Herrmann, R1
Musch, E1
Termander, B1
Hunstein, W1
Hansen, MM1
Andersen, E1
Christensen, BE1
Christiansen, I1
Geisler, C1
Kristensen, D1
Jensen, KB1
Junker, P1
Jootar, S1
Nitiyanant, P1
Ratanaprakarn, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase II Clinical Protocol for the Treatment of Patients With Previously Untreated CLL With Four or Six Cycles of Fludarabine and Cyclophosphamide With Rituximab (FCR) Plus Lenalidomide Followed by Lenalidomide Consolidation/ Maintenance[NCT01723839]Phase 221 participants (Actual)Interventional2012-02-22Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Complete Response

Analysis of the Primary Endpoint: The complete responses will be estimated by the number of patients with CR divided by the total number of evaluable patients. (NCT01723839)
Timeframe: 28 day cycle, up to 4 cycles

InterventionPercentage of Participants (Number)
FCR With Lenalidomide45

Overall Response Rate

Analysis of the other Secondary Endpoints: The overall response rate will be estimated by the number of patients with complete and partial responses divided by the total number of evaluable patients. (NCT01723839)
Timeframe: 28 day cycle, up to 6 cycles

InterventionPercentage of Participants (Number)
FCR With Lenalidomide95

Reviews

2 reviews available for prednisolone and B-Cell Chronic Lymphocytic Leukemia

ArticleYear
Anterior chamber fibrinoid syndrome after cataract extraction in a patient on ibrutinib for B-cell chronic lymphocytic leukemia: a case report and review of the literature.
    Journal of medical case reports, 2018, Nov-16, Volume: 12, Issue:1

    Topics: Adenine; Administration, Topical; Aged; Anterior Chamber; Antihypertensive Agents; Antineoplastic Ag

2018
Outcome of advanced chronic lymphocytic leukemia following different first-line and relapse therapies: a meta-analysis of five prospective trials by the German CLL Study Group (GCLLSG).
    Haematologica, 2015, Volume: 100, Issue:11

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase II a

2015

Trials

8 trials available for prednisolone and B-Cell Chronic Lymphocytic Leukemia

ArticleYear
First-line therapy in chronic lymphocytic leukemia: a Swedish nation-wide real-world study on 1053 consecutive patients treated between 2007 and 2013.
    Haematologica, 2019, Volume: 104, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydroch

2019
Fludarabine with cytarabine followed by reduced-intensity conditioning and allogeneic hematopoietic stem cell transplantation in patients with poor-risk chronic lymphocytic leukemia.
    Annals of hematology, 2013, Volume: 92, Issue:2

    Topics: Adult; Alemtuzumab; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antin

2013
Initial chemotherapy with mitoxantrone, chlorambucil, prednisone impairs the collection of stem cells in patients with indolent lymphomas--results of a randomized comparison by the German Low-Grade Lymphoma Study Group.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2007, Volume: 18, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Chlorambucil; Cyclophospham

2007
Methylprednisolone in advanced chronic lymphocytic leukaemia: rationale for, and effectiveness of treatment suggested by DiSC assay.
    Acta haematologica, 1995, Volume: 93, Issue:2-4

    Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cell Survival; C

1995
Long-term follow-up of patients with chronic lymphocytic leukemia (CLL) receiving fludarabine regimens as initial therapy.
    Blood, 1998, Aug-15, Volume: 92, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherap

1998
Liposomal daunorubicin (DaunoXome) in combination with cyclophosphamide, vincristine and prednisolone (COP-X) as salvage therapy in poor-prognosis non-Hodgkins lymphoma.
    Leukemia & lymphoma, 2001, Volume: 42, Issue:1-2

    Topics: Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide;

2001
Prognostic significance of glucocorticoid receptor determination in patients with chronic lymphocytic leukemia and immunocytoma--lack of a positive correlation between receptor levels and clinical responsiveness.
    Leukemia research, 1990, Volume: 14, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Chlorambucil; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell

1990
CHOP versus prednisolone + chlorambucil in chronic lymphocytic leukemia (CLL): preliminary results of a randomized multicenter study.
    Nouvelle revue francaise d'hematologie, 1988, Volume: 30, Issue:5-6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Clinical Trials as Topic;

1988

Other Studies

70 other studies available for prednisolone and B-Cell Chronic Lymphocytic Leukemia

ArticleYear
Cryoglobulinemic vasculitis with interruption of ibrutinib therapy for chronic lymphocytic leukemia (CLL).
    International journal of hematology, 2019, Volume: 110, Issue:6

    Topics: Adenine; Aged; Cryoglobulinemia; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Piperidines;

2019
Ibrutinib-associated oral ulcers.
    Oral oncology, 2020, Volume: 100

    Topics: Adenine; Aged; Combined Modality Therapy; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Metr

2020
Epstein-Barr virus-positive mucocutaneous ulcer in a patient with untreated chronic lymphocytic leukemia and hypogammaglobulinemia.
    The Journal of dermatology, 2020, Volume: 47, Issue:5

    Topics: Agammaglobulinemia; Aged; Biopsy; Cyclophosphamide; Drug Therapy, Combination; Epstein-Barr Virus In

2020
Monoclonal B-cell Lymphocytosis Exacerbated by Prednisolone Therapy for Dermatomyositis.
    Internal medicine (Tokyo, Japan), 2021, Sep-01, Volume: 60, Issue:17

    Topics: B-Lymphocytes; Dermatomyositis; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytosis; Predn

2021
PHAGOCYTOSIS AND EXPRESSION OF FCg-RECEPTORS AND CD180 ON MONOCYTES IN CHRONIC LYMPHOCYTIC LEUKEMIA.
    Georgian medical news, 2017, Issue:270

    Topics: Aged; Aged, 80 and over; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Case-Control

2017
Polymyalgia rheumatica development in a patient under PI3K inhibitor therapy for chronic lymphocytic leukaemia.
    BMJ case reports, 2017, Nov-08, Volume: 2017

    Topics: Aged, 80 and over; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols;

2017
Sequential development of monoclonal B cell lymphocytosis-derived small lymphocytic lymphoma and plasma cell leukemia.
    Annals of hematology, 2018, Volume: 97, Issue:5

    Topics: Aged, 80 and over; Anemia, Hemolytic, Autoimmune; Antigens, CD; Antineoplastic Combined Chemotherapy

2018
Lymphocytic leukemia in a captive dhole (Cuon alpinus).
    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2013, Volume: 44, Issue:1

    Topics: Animals; Canidae; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Melphalan; Prednisolone

2013
Orbital richter syndrome.
    Orbit (Amsterdam, Netherlands), 2013, Volume: 32, Issue:6

    Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Biomarkers,

2013
Successful treatment of acquired pure red cell aplasia with oral corticosteroids in a patient with B-cell CLL.
    BMJ case reports, 2013, Nov-14, Volume: 2013

    Topics: Administration, Oral; Adrenal Cortex Hormones; Bone Marrow; Diagnosis, Differential; Humans; Leukemi

2013
[Case report; Disseminated Mycobacterium abscessus infection with hemophagocytic syndrome during treatment of chronic lymphocytic leukemia].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2014, Mar-10, Volume: 103, Issue:3

    Topics: Amikacin; Anemia, Hemolytic, Autoimmune; Anti-Bacterial Agents; Clarithromycin; Cyclophosphamide; Hu

2014
Clinical significance of bax/bcl-2 ratio in chronic lymphocytic leukemia.
    Haematologica, 2016, Volume: 101, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; bcl-2-Associated X P

2016
Eosinophilic dermatosis of haematological malignancy.
    Clinical and experimental dermatology, 2016, Volume: 41, Issue:6

    Topics: Administration, Oral; Eosinophilia; Glucocorticoids; Hematologic Neoplasms; Humans; Leukemia, Lympho

2016
[Hepatitis B virus reactivation during chlorambucil and prednisolone treatment in an HBsAg-negative and anti-HBs-positive patient with B-cell chronic lymphocytic leukemia].
    The Korean journal of hepatology, 2008, Volume: 14, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Female; Hepatitis B; Hepatitis B

2008
In vitro activity of 20 agents in different prognostic subgroups of chronic lymphocytic leukemia--rolipram and prednisolone active in cells from patients with poor prognosis.
    European journal of haematology, 2009, Volume: 83, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Case-Control Studies; Chromosome Deletion; Ch

2009
Renal dysfunction due to leukemic infiltration of kidneys in a case of chronic lymphocytic leukemia.
    Hemodialysis international. International Symposium on Home Hemodialysis, 2010, Volume: 14, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Female; Humans; Kidney; Leukemia,

2010
[MRSA infection of the hand in immunodeficient patients].
    Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V..., 2009, Volume: 41, Issue:5

    Topics: Aged; Amputation, Surgical; Anti-Bacterial Agents; Antineoplastic Agents, Hormonal; Combined Modalit

2009
Ocular and cerebral aspergillosis in a non-neutropenic patient following alemtuzumab and methyl prednisolone treatment for chronic lymphocytic leukaemia.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2010, Volume: 16, Issue:2

    Topics: Aged; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm;

2010
Richter's syndrome of the brain and the spinal cord.
    Journal of neurology, neurosurgery, and psychiatry, 2011, Volume: 82, Issue:8

    Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Central Nerv

2011
Paraneoplastic pemphigus characterized by polymorphic oral mucosal manifestations--report of two cases.
    Quintessence international (Berlin, Germany : 1985), 2010, Volume: 41, Issue:8

    Topics: Aged; Diagnosis, Differential; Female; Fluorescent Antibody Technique, Direct; Fluorescent Antibody

2010
Chronic lymphoid leukemia cells are highly sensitive to the combination of prednisolone and daunorubicin, but much less to doxorubicin or epirubicin.
    Experimental hematology, 2010, Volume: 38, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Cluster Analysis; Daunorubicin; Doxorubi

2010
Something fishy in the immunocompromised.
    British journal of haematology, 2011, Volume: 153, Issue:2

    Topics: Anti-Infective Agents; Antineoplastic Combined Chemotherapy Protocols; Cyclosporine; Fatal Outcome;

2011
Richter syndrome in chronic lymphocytic leukaemia manifesting only as tumorous hepatomegaly.
    British journal of haematology, 2011, Volume: 155, Issue:2

    Topics: Adrenal Cortex Hormones; Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemo

2011
Preliminary experience with the use of bendamustine: a peculiar skin rash as the commonest side effect.
    Hematology/oncology and stem cell therapy, 2011, Volume: 4, Issue:4

    Topics: Adult; Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents, Alkylating; Bendamustine

2011
[Detection and impact of minimal residual disease on outcome of chronic lymphocytic leukemia].
    Orvosi hetilap, 2012, Oct-14, Volume: 153, Issue:41

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Disease-Free Survival

2012
Exacerbation of lymphomatoid papulosis during rituximab therapy.
    The Australasian journal of dermatology, 2014, Volume: 55, Issue:1

    Topics: Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Cyclop

2014
Subcorneal pustular dermatosis in association with chronic lymphocytic leukaemia.
    Acta dermato-venereologica, 2003, Volume: 83, Issue:4

    Topics: Aged; Axilla; Diagnosis, Differential; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Predn

2003
Chronic lymphocytic leukemia and multiple myeloma in the same patient: case report.
    Leukemia & lymphoma, 2003, Volume: 44, Issue:8

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocytes; Bone Neoplasms; Chlorambucil; C

2003
[Corticosteroid therapy of chronic lymphatic leukemia].
    Deutsche medizinische Wochenschrift (1946), 1963, May-31, Volume: 88

    Topics: Adrenal Cortex Hormones; Humans; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoi

1963
PREDNISOLONE SENSITIVITY AND CYTOLOGY OF VIABLE LYMPHOCYTES AS TESTS FOR CHRONIC LYMPHOCYTIC LEUKEMIA.
    Journal of the National Cancer Institute, 1964, Volume: 33

    Topics: Humans; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Lymphocytes; Lymphocyt

1964
Treatment of chronic lymphocytic leukaemia in three dogs with melphalan and prednisolone.
    The Journal of small animal practice, 2004, Volume: 45, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Blood Cell Count; Blood Chemical Analysis; Blood Platele

2004
VH gene mutation status and cellular drug resistance in chronic lymphocytic leukaemia.
    European journal of haematology, 2004, Volume: 73, Issue:6

    Topics: Antineoplastic Agents; Cell Differentiation; Cell Line, Tumor; Cladribine; Cyclophosphamide; Cytarab

2004
Fludarabine as a second-line treatment of advanced stage chronic lymphocytic leukemia.
    Saudi medical journal, 2004, Volume: 25, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cause of Death; Chlorambucil; Female; Follow-U

2004
Successful treatment of a patient with chronic lymphocytic leukaemia (CLL) presenting with bony metastases with aggressive antibody and chemotherapy.
    Clinical and laboratory haematology, 2005, Volume: 27, Issue:6

    Topics: Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Co

2005
Fludarabine-associated autoimmune hemolytic anemia occurring in B-cell chronic lymphocytic leukemia.
    Leukemia research, 2006, Volume: 30, Issue:12

    Topics: Aged, 80 and over; Anemia, Hemolytic, Autoimmune; Antibodies, Monoclonal; Antibodies, Monoclonal, Mu

2006
[Mantle cell lymphoma mimicking chronic lymphocytic leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2005, Volume: 46, Issue:1

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy

2005
Paraneoplastic pemphigus in association with B-cell lymphocytic leukemia and hepatitis C: favorable response to intravenous immunoglobulins and prednisolone.
    International journal of dermatology, 2007, Volume: 46, Issue:7

    Topics: Desmoglein 3; Fluorescent Antibody Technique; Glucocorticoids; Hepatitis C; Humans; Immunoglobulins,

2007
Erythema annulare centrifugum associated with chronic lymphocytic leukaemia.
    The British journal of dermatology, 2007, Volume: 157, Issue:5

    Topics: Aged; Erythema; Female; Glucocorticoids; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Prednisolon

2007
Why R-CHOP for first line treatment of chronic lymphocytic leukemia?
    International journal of laboratory hematology, 2007, Volume: 29, Issue:6

    Topics: Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Co

2007
[Atypical ocular toxoplasmosis with concomitant ocular reactivation of varicella-zoster virus and cytomegalovirus in an immunocompromised host].
    Klinische Monatsblatter fur Augenheilkunde, 2008, Volume: 225, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Blindness; Chlorambucil; Chorioretinitis; Como

2008
CD23 antigen density is related to serum gamma globulin level, bone marrow reticulin pattern, and treatment in B chronic lymphocytic leukemia.
    Leukemia & lymphoma, 1994, Volume: 13, Issue:1-2

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone

1994
Reversible functional asplenia. Autoimmune hemolytic anemia with thrombocytopenia in chronic lymphocytic leukemia.
    Clinical nuclear medicine, 1994, Volume: 19, Issue:8

    Topics: Anemia, Hemolytic, Autoimmune; Erythrocytes; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell;

1994
Renal failure caused by leukaemic infiltration in chronic lymphocytic leukaemia.
    Journal of clinical pathology, 1993, Volume: 46, Issue:12

    Topics: Chlorambucil; Combined Modality Therapy; Humans; Kidney; Kidney Failure, Chronic; Leukemia, Lymphocy

1993
Chronic lymphocytic leukemia associated with bone marrow fibrosis: possible role of interleukin 1 alpha in the pathogenesis.
    American journal of hematology, 1993, Volume: 43, Issue:1

    Topics: Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cell Division; Cells, Cul

1993
[Erythroblastopenia in chronic lymphoid leukemia: value of corticoids-cyclosporine combination].
    Presse medicale (Paris, France : 1983), 1993, Jun-26, Volume: 22, Issue:23

    Topics: Cyclosporine; Drug Therapy, Combination; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Mid

1993
[A case of B-chronic lymphocytic leukemia/prolymphocytic leukemia (CLL/PL)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Drug Administration S

1993
Clinical spectrum of autoimmune haemolytic anaemia in patients with chronic lymphocytic leukaemia.
    Leukemia & lymphoma, 1993, Volume: 9, Issue:1-2

    Topics: Aged; Anemia, Hemolytic, Autoimmune; Azathioprine; Chlorambucil; Cyclophosphamide; Drug Therapy, Com

1993
Ocular lymphoma in a patient with chronic lymphocytic leukemia.
    American journal of ophthalmology, 1996, Volume: 122, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Biopsy; Combined Modality Therapy; Eye Neo

1996
Chronic lymphocytic leukaemia with upper airway obstruction.
    Leukemia & lymphoma, 1996, Volume: 20, Issue:5-6

    Topics: Airway Obstruction; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamide;

1996
Multiple lymphomatous polyposis of the gastrointestinal tract: prospective clinicopathologic study of 31 cases. Groupe D'étude des Lymphomes Digestifs.
    Gastroenterology, 1997, Volume: 112, Issue:1

    Topics: Adult; Aged; Antigens, CD; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Bioma

1997
Steroid-responsive interstitial pneumonitis after fludarabine therapy.
    Chest, 1997, Volume: 111, Issue:5

    Topics: Aged; Anti-Inflammatory Agents; Antineoplastic Agents; Cough; Fatal Outcome; Glucocorticoids; Humans

1997
Functional adrenocortical adenoma in a case with B cell chronic lymphoproliferative disorder.
    Acta haematologica, 1997, Volume: 97, Issue:4

    Topics: Adenoma; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenalectomy; Antineoplastic Combined C

1997
Hypofibrinogenemia induced by prednisolone therapy in a patient with chronic lymphocytic leukemia complicated with autoimmune hemolytic anemia.
    American journal of hematology, 1997, Volume: 55, Issue:3

    Topics: Afibrinogenemia; Anemia, Hemolytic, Autoimmune; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male

1997
Acute polyneuropathy with chronic lymphocytic leukaemia and paraproteinaemia: response to chlorambucil and prednisolone.
    Journal of neurology, neurosurgery, and psychiatry, 1998, Volume: 64, Issue:4

    Topics: Acute Disease; Aged; Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Chlorambucil; Demy

1998
Ex vivo assessment of drug response by differential staining cytotoxicity (DiSC) assay suggests a biological basis for equality of chemotherapy irrespective of age for patients with chronic lymphocytic leukaemia.
    Leukemia, 2000, Volume: 14, Issue:4

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; Chlorambucil; Cladribine; Comorb

2000
Successful treatment of a patient with nephrotic syndrome associated with chronic lymphocytic leukemia.
    Internal medicine (Tokyo, Japan), 2000, Volume: 39, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Biopsy; Cyclophosphamide; Drug Therapy, Combination; Enala

2000
Autoimmune hemolytic anemia in chronic lymphocytic leukemia: clinical, therapeutic, and prognostic features.
    Blood, 2000, May-01, Volume: 95, Issue:9

    Topics: Aged; Aged, 80 and over; Anemia, Hemolytic, Autoimmune; Antineoplastic Combined Chemotherapy Protoco

2000
Secondary cutaneous infiltration in B cell chronic lymphocytic leukemia.
    Acta haematologica, 2000, Volume: 103, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamide; Doxorubicin; Histidi

2000
Calcium antagonists potentiate P-glycoprotein-independent anticancer drugs in chronic lymphocytic leukemia cells in vitro.
    Haematologica, 2000, Volume: 85, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member

2000
Acquired Factor VIII autoantibody: four cases demonstrating the heterogenous nature of this condition and problems involved in diagnosis and treatment.
    European journal of haematology, 2001, Volume: 66, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Autoantibodies; Autoimmune Diseases; Azathiop

2001
Pure red cell aplasia associated with small lymphocytic lymphoma.
    British journal of haematology, 2001, Volume: 113, Issue:2

    Topics: Anemia, Aplastic; B-Lymphocytes; CD8-Positive T-Lymphocytes; Cyclophosphamide; Drug Therapy, Combina

2001
Retrospective study of the prognostic role of serum thymidine kinase level in CLL patients with active disease treated with fludarabine.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2001, Volume: 12, Issue:5

    Topics: Aged; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Female; Humans; Leu

2001
Rippling muscle syndrome preceding malignant lymphoma.
    Internal medicine (Tokyo, Japan), 2002, Volume: 41, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Electromyography; Hyp

2002
Membranoproliferative glomerulonephritis in association with chronic lymphocytic leukaemia: a report of three cases.
    Pathology, 2002, Volume: 34, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Chlorambucil; Drug Therapy, Combination; Female; Glomerular Mesa

2002
Endobronchial involvement with Waldenström's macroglobulinemia.
    Internal medicine (Tokyo, Japan), 1992, Volume: 31, Issue:9

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bronchial Neoplasms; Cyclophosphamide; Dyspnea

1992
[Chronic lymphocytic leukemia diagnosed after corticosteroid therapy for Evans syndrome].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1992, Volume: 33, Issue:6

    Topics: Anemia, Hemolytic; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukocyte Count; Lymphocy

1992
Retinal detachments due to chronic lymphocytic leukaemia.
    Clinical and laboratory haematology, 1991, Volume: 13, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Combined Modality Therapy; Humans; Leu

1991
[B-chronic lymphocytic leukemia/prolymphocytic leukemia (CLL/PL)--a case report].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1990, Volume: 31, Issue:11

    Topics: Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cyclophosphamide; D

1990
[Accessory use of protease-inhibiting agents for disease remission in a patient with autoimmune hemolytic anemia associated with B-CLL].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1990, Volume: 31, Issue:2

    Topics: Aged; Anemia, Hemolytic, Autoimmune; Benzamidines; Complement Activation; Complement Inactivator Pro

1990
Angioimmunoblastic lymphadenopathy with dysproteinemia in Thailand.
    Asian Pacific journal of allergy and immunology, 1987, Volume: 5, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dysgammaglobulinemia;

1987