Page last updated: 2024-11-06

prednisolone and Atheroma

prednisolone has been researched along with Atheroma in 5 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Research Excerpts

ExcerptRelevanceReference
"Atherosclerosis is a lipid-driven inflammatory disease, for which nanomedicinal interventions are under evaluation."5.43Liposomal prednisolone promotes macrophage lipotoxicity in experimental atherosclerosis. ( Alaarg, A; Dallinga-Thie, GM; de Winther, M; Hamers, AA; Laudes, M; Lutgens, E; Meiler, S; Metselaar, JM; Mulder, WJ; Schulte, DM; Seijkens, T; Stroes, ES; Tang, J; Van den Bossche, J; van der Valk, FM; Zheng, KH, 2016)
" Our paper details the first clinical studies of a liposomal nanoparticle encapsulating prednisolone (LN-PLP) in atherosclerosis."5.20Prednisolone-containing liposomes accumulate in human atherosclerotic macrophages upon intravenous administration. ( Calcagno, C; Dallinga-Thie, GM; Fayad, ZA; Legemate, DA; Lobatto, ME; Mani, V; Metselaar, JM; Mulder, WJ; Nederveen, AJ; Nieuwdorp, M; Otten, MJ; Paridaans, MP; Ramachandran, S; Schulte, DM; Storm, G; Stroes, ES; van der Valk, FM; van Wijk, DF; Verberne, HJ; Willems, MC, 2015)
" History of lupus nephritis and a higher average dose of prednisolone used since diagnosis were associated with cIMT progression in patients."3.96Similar progression of carotid intima-media thickness in 7-year surveillance of patients with mild SLE and controls, but this progression is still promoted by dyslipidaemia, lower HDL levels, hypertension, history of lupus nephritis and a higher prednisol ( Ajeganova, S; Frostegård, J; Gustafsson, T; Hafström, I; Lindberg, L, 2020)
"Atherosclerosis is a lipid-driven inflammatory disease, for which nanomedicinal interventions are under evaluation."1.43Liposomal prednisolone promotes macrophage lipotoxicity in experimental atherosclerosis. ( Alaarg, A; Dallinga-Thie, GM; de Winther, M; Hamers, AA; Laudes, M; Lutgens, E; Meiler, S; Metselaar, JM; Mulder, WJ; Schulte, DM; Seijkens, T; Stroes, ES; Tang, J; Van den Bossche, J; van der Valk, FM; Zheng, KH, 2016)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Ajeganova, S1
Gustafsson, T1
Lindberg, L1
Hafström, I1
Frostegård, J1
van der Valk, FM3
van Wijk, DF1
Lobatto, ME1
Verberne, HJ1
Storm, G2
Willems, MC1
Legemate, DA1
Nederveen, AJ1
Calcagno, C1
Mani, V1
Ramachandran, S1
Paridaans, MP1
Otten, MJ1
Dallinga-Thie, GM2
Fayad, ZA1
Nieuwdorp, M1
Schulte, DM3
Metselaar, JM3
Mulder, WJ2
Stroes, ES3
Meiler, S1
Tang, J1
Zheng, KH2
Van den Bossche, J1
Seijkens, T1
Laudes, M1
de Winther, M1
Lutgens, E1
Alaarg, A2
Hamers, AA2
da Silva, AE1
Versloot, M1
van Ufford, LC1
Arida, A1
Protogerou, AD1
Konstantonis, G1
Fragiadaki, K1
Kitas, GD1
Sfikakis, PP1

Trials

1 trial available for prednisolone and Atheroma

ArticleYear
Prednisolone-containing liposomes accumulate in human atherosclerotic macrophages upon intravenous administration.
    Nanomedicine : nanotechnology, biology, and medicine, 2015, Volume: 11, Issue:5

    Topics: Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Arteries; Atherosclerosis; Femal

2015

Other Studies

4 other studies available for prednisolone and Atheroma

ArticleYear
Similar progression of carotid intima-media thickness in 7-year surveillance of patients with mild SLE and controls, but this progression is still promoted by dyslipidaemia, lower HDL levels, hypertension, history of lupus nephritis and a higher prednisol
    Lupus science & medicine, 2020, Volume: 7, Issue:1

    Topics: Adult; Aged; Cardiovascular Diseases; Carotid Artery Diseases; Carotid Intima-Media Thickness; Case-

2020
Liposomal prednisolone promotes macrophage lipotoxicity in experimental atherosclerosis.
    Nanomedicine : nanotechnology, biology, and medicine, 2016, Volume: 12, Issue:6

    Topics: Animals; Atherosclerosis; Humans; Liposomes; Macrophages; Mice; Plaque, Atherosclerotic; Prednisolon

2016
Multiple pathway assessment to predict anti-atherogenic efficacy of drugs targeting macrophages in atherosclerotic plaques.
    Vascular pharmacology, 2016, Volume: 82

    Topics: Animals; Anti-Inflammatory Agents; Atherosclerosis; Cell Proliferation; Cytokines; Endoplasmic Retic

2016
Atherosclerosis is not accelerated in rheumatoid arthritis of low activity or remission, regardless of antirheumatic treatment modalities.
    Rheumatology (Oxford, England), 2017, 06-01, Volume: 56, Issue:6

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Atherosclerosis; Biological Factors; Carotid Artery Dis

2017