Page last updated: 2024-11-06

prednisolone and Anemia, Sickle Cell

prednisolone has been researched along with Anemia, Sickle Cell in 7 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Anemia, Sickle Cell: A disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for hemoglobin S.

Research Excerpts

ExcerptRelevanceReference
" We conducted a preclinical trial of dissociative (vamorolone) and conventional (prednisolone) corticosteroid compounds to evaluate their effects on nociception phenotype, inflammation, and organ dysfunction in SCD mice."3.88The corticosteroid compounds prednisolone and vamorolone do not alter the nociception phenotype and exacerbate liver injury in sickle cell mice. ( Afsar, N; Albani, S; Almeida, LEF; Damsker, JM; Gordish-Dressman, H; Kamimura, S; Kleiner, DE; Pratt, D; Quezado, M; Quezado, ZMN, 2018)
"Polymyositis is an inflammatory myopathy which, like SCD, may present with myalgia but is usually associated with proximal muscle weakness."1.42Juvenile polymyositis with unremitting pain and progressive loss of motor and bulbar function on a background of sickle cell disease. ( Bali, S; D'Cruz, D; Inusa, BP; Lazaro, M, 2015)
"This case of transverse myelitis is related to varicella zoster infection, with sickle cell anemia, and was successfully treated with high dose IV methylprednisolone, IV acyclovir, and physiotherapy."1.37Zoster myelitis in sickle cell anemia. ( Makkawi, SO; Mousali, YM; Sobhi, EM, 2011)
"We report 2 children with sickle cell anemia who were diagnosed with DHTR and experienced a subsequent neurologic event in the course of treatment with corticosteroids."1.35Severe neurologic complication after delayed hemolytic transfusion reaction in 2 children with sickle cell anemia: significant diagnosis and therapeutic challenges. ( Bertrand, Y; Elenga, N; Galambrun, C; Kebaïli, K; Mialou, V; Pondarre, C, 2008)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's4 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Almeida, LEF1
Damsker, JM1
Albani, S1
Afsar, N1
Kamimura, S1
Pratt, D1
Kleiner, DE1
Quezado, M1
Gordish-Dressman, H1
Quezado, ZMN1
Bali, S1
D'Cruz, D1
Lazaro, M1
Inusa, BP1
Elenga, N1
Mialou, V1
Kebaïli, K1
Galambrun, C1
Bertrand, Y1
Pondarre, C1
Mousali, YM1
Sobhi, EM1
Makkawi, SO1
Alkindi, S1
Arafa, N1
Al Okbi, M1
Pathare, A1
GHOSE, S1
CHATTERJEA, JB1
Strouse, JJ1
Takemoto, CM1
Keefer, JR1
Kato, GJ1
Casella, JF1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase II Open-Label, Multiple Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Exploratory Efficacy of Vamorolone in Boys Ages 2 to <4 Years and 7 to <18 Years With Duchenne Muscular Dystrophy (DMD)[NCT05185622]Phase 254 participants (Anticipated)Interventional2022-03-21Recruiting
A Phase II Pilot Trial of Vamorolone vs. Placebo for the Treatment of Becker Muscular Dystrophy[NCT05166109]Phase 239 participants (Anticipated)Interventional2022-07-07Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for prednisolone and Anemia, Sickle Cell

ArticleYear
Corticosteroids and increased risk of readmission after acute chest syndrome in children with sickle cell disease.
    Pediatric blood & cancer, 2008, Volume: 50, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Anemia, Sickle Cell; Asthma; Blood Transfusion; Child; Child, Pres

2008

Other Studies

6 other studies available for prednisolone and Anemia, Sickle Cell

ArticleYear
The corticosteroid compounds prednisolone and vamorolone do not alter the nociception phenotype and exacerbate liver injury in sickle cell mice.
    Scientific reports, 2018, 04-17, Volume: 8, Issue:1

    Topics: Anemia, Sickle Cell; Animals; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Fema

2018
The corticosteroid compounds prednisolone and vamorolone do not alter the nociception phenotype and exacerbate liver injury in sickle cell mice.
    Scientific reports, 2018, 04-17, Volume: 8, Issue:1

    Topics: Anemia, Sickle Cell; Animals; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Fema

2018
The corticosteroid compounds prednisolone and vamorolone do not alter the nociception phenotype and exacerbate liver injury in sickle cell mice.
    Scientific reports, 2018, 04-17, Volume: 8, Issue:1

    Topics: Anemia, Sickle Cell; Animals; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Fema

2018
The corticosteroid compounds prednisolone and vamorolone do not alter the nociception phenotype and exacerbate liver injury in sickle cell mice.
    Scientific reports, 2018, 04-17, Volume: 8, Issue:1

    Topics: Anemia, Sickle Cell; Animals; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Fema

2018
Juvenile polymyositis with unremitting pain and progressive loss of motor and bulbar function on a background of sickle cell disease.
    BMJ case reports, 2015, Mar-27, Volume: 2015

    Topics: Adolescent; Adrenal Cortex Hormones; Anemia, Sickle Cell; Anti-Inflammatory Agents; Autoimmunity; Az

2015
Severe neurologic complication after delayed hemolytic transfusion reaction in 2 children with sickle cell anemia: significant diagnosis and therapeutic challenges.
    Journal of pediatric hematology/oncology, 2008, Volume: 30, Issue:12

    Topics: Adolescent; Anemia, Hemolytic; Anemia, Sickle Cell; Brain Diseases; Child; Erythrocyte Transfusion;

2008
Zoster myelitis in sickle cell anemia.
    Neurosciences (Riyadh, Saudi Arabia), 2011, Volume: 16, Issue:3

    Topics: Adolescent; Anemia, Sickle Cell; Anti-Inflammatory Agents; Female; Herpes Zoster; Humans; Injections

2011
Complete recovery following sudden sensorineural hearing loss in a patient with sickle cell disease.
    Hematology/oncology and stem cell therapy, 2011, Volume: 4, Issue:2

    Topics: Administration, Oral; Adult; Anemia, Sickle Cell; Exchange Transfusion, Whole Blood; Female; Glucoco

2011
INFLUENCE OF NUCLEATED CELLS ON SICKLING PHENOMENON.
    Journal of the Indian Medical Association, 1964, Feb-01, Volume: 42

    Topics: Anemia, Sickle Cell; Eosinophilia; Erythrocytes; Humans; Kwashiorkor; Leukemia; Leukemia, Lymphoid;

1964