prednisolone has been researched along with Anemia, Sickle Cell in 7 studies
Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.
Anemia, Sickle Cell: A disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for hemoglobin S.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We conducted a preclinical trial of dissociative (vamorolone) and conventional (prednisolone) corticosteroid compounds to evaluate their effects on nociception phenotype, inflammation, and organ dysfunction in SCD mice." | 3.88 | The corticosteroid compounds prednisolone and vamorolone do not alter the nociception phenotype and exacerbate liver injury in sickle cell mice. ( Afsar, N; Albani, S; Almeida, LEF; Damsker, JM; Gordish-Dressman, H; Kamimura, S; Kleiner, DE; Pratt, D; Quezado, M; Quezado, ZMN, 2018) |
| "Polymyositis is an inflammatory myopathy which, like SCD, may present with myalgia but is usually associated with proximal muscle weakness." | 1.42 | Juvenile polymyositis with unremitting pain and progressive loss of motor and bulbar function on a background of sickle cell disease. ( Bali, S; D'Cruz, D; Inusa, BP; Lazaro, M, 2015) |
| "This case of transverse myelitis is related to varicella zoster infection, with sickle cell anemia, and was successfully treated with high dose IV methylprednisolone, IV acyclovir, and physiotherapy." | 1.37 | Zoster myelitis in sickle cell anemia. ( Makkawi, SO; Mousali, YM; Sobhi, EM, 2011) |
| "We report 2 children with sickle cell anemia who were diagnosed with DHTR and experienced a subsequent neurologic event in the course of treatment with corticosteroids." | 1.35 | Severe neurologic complication after delayed hemolytic transfusion reaction in 2 children with sickle cell anemia: significant diagnosis and therapeutic challenges. ( Bertrand, Y; Elenga, N; Galambrun, C; Kebaïli, K; Mialou, V; Pondarre, C, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Almeida, LEF | 1 |
| Damsker, JM | 1 |
| Albani, S | 1 |
| Afsar, N | 1 |
| Kamimura, S | 1 |
| Pratt, D | 1 |
| Kleiner, DE | 1 |
| Quezado, M | 1 |
| Gordish-Dressman, H | 1 |
| Quezado, ZMN | 1 |
| Bali, S | 1 |
| D'Cruz, D | 1 |
| Lazaro, M | 1 |
| Inusa, BP | 1 |
| Elenga, N | 1 |
| Mialou, V | 1 |
| Kebaïli, K | 1 |
| Galambrun, C | 1 |
| Bertrand, Y | 1 |
| Pondarre, C | 1 |
| Mousali, YM | 1 |
| Sobhi, EM | 1 |
| Makkawi, SO | 1 |
| Alkindi, S | 1 |
| Arafa, N | 1 |
| Al Okbi, M | 1 |
| Pathare, A | 1 |
| GHOSE, S | 1 |
| CHATTERJEA, JB | 1 |
| Strouse, JJ | 1 |
| Takemoto, CM | 1 |
| Keefer, JR | 1 |
| Kato, GJ | 1 |
| Casella, JF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase II Open-Label, Multiple Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Exploratory Efficacy of Vamorolone in Boys Ages 2 to <4 Years and 7 to <18 Years With Duchenne Muscular Dystrophy (DMD)[NCT05185622] | Phase 2 | 54 participants (Anticipated) | Interventional | 2022-03-21 | Recruiting | ||
| A Phase II Pilot Trial of Vamorolone vs. Placebo for the Treatment of Becker Muscular Dystrophy[NCT05166109] | Phase 2 | 39 participants (Anticipated) | Interventional | 2022-07-07 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for prednisolone and Anemia, Sickle Cell
| Article | Year |
|---|---|
Corticosteroids and increased risk of readmission after acute chest syndrome in children with sickle cell disease.
Topics: Acute Disease; Adolescent; Adult; Anemia, Sickle Cell; Asthma; Blood Transfusion; Child; Child, Pres | 2008 |
6 other studies available for prednisolone and Anemia, Sickle Cell
| Article | Year |
|---|---|
The corticosteroid compounds prednisolone and vamorolone do not alter the nociception phenotype and exacerbate liver injury in sickle cell mice.
Topics: Anemia, Sickle Cell; Animals; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Fema | 2018 |
The corticosteroid compounds prednisolone and vamorolone do not alter the nociception phenotype and exacerbate liver injury in sickle cell mice.
Topics: Anemia, Sickle Cell; Animals; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Fema | 2018 |
The corticosteroid compounds prednisolone and vamorolone do not alter the nociception phenotype and exacerbate liver injury in sickle cell mice.
Topics: Anemia, Sickle Cell; Animals; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Fema | 2018 |
The corticosteroid compounds prednisolone and vamorolone do not alter the nociception phenotype and exacerbate liver injury in sickle cell mice.
Topics: Anemia, Sickle Cell; Animals; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Fema | 2018 |
Juvenile polymyositis with unremitting pain and progressive loss of motor and bulbar function on a background of sickle cell disease.
Topics: Adolescent; Adrenal Cortex Hormones; Anemia, Sickle Cell; Anti-Inflammatory Agents; Autoimmunity; Az | 2015 |
Severe neurologic complication after delayed hemolytic transfusion reaction in 2 children with sickle cell anemia: significant diagnosis and therapeutic challenges.
Topics: Adolescent; Anemia, Hemolytic; Anemia, Sickle Cell; Brain Diseases; Child; Erythrocyte Transfusion; | 2008 |
Zoster myelitis in sickle cell anemia.
Topics: Adolescent; Anemia, Sickle Cell; Anti-Inflammatory Agents; Female; Herpes Zoster; Humans; Injections | 2011 |
Complete recovery following sudden sensorineural hearing loss in a patient with sickle cell disease.
Topics: Administration, Oral; Adult; Anemia, Sickle Cell; Exchange Transfusion, Whole Blood; Female; Glucoco | 2011 |
INFLUENCE OF NUCLEATED CELLS ON SICKLING PHENOMENON.
Topics: Anemia, Sickle Cell; Eosinophilia; Erythrocytes; Humans; Kwashiorkor; Leukemia; Leukemia, Lymphoid; | 1964 |