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prednisolone and Anastomotic Leak

prednisolone has been researched along with Anastomotic Leak in 2 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Anastomotic Leak: Breakdown of the connection and subsequent leakage of effluent (fluids, secretions, air) from a SURGICAL ANASTOMOSIS of the digestive, respiratory, genitourinary, and cardiovascular systems. Most common leakages are from the breakdown of suture lines in gastrointestinal or bowel anastomosis.

Research Excerpts

ExcerptRelevanceReference
"While high-dose prednisolone treatment led to an increased anastomotic leakage rate in mice under colitis, low-dose prednisolone treatment limited preoperative disease activity and did not influence the leakage rate."8.31Perioperative Low-Dose Prednisolone Treatment Has Beneficial Effects on Postoperative Recovery and Anastomotic Healing in a Murine Colitis Model. ( Bauer, J; Buck, A; Clees, Z; Friess, H; Kasajima, A; Neumann, PA; Oertel, R; Reischl, S; Weber, MC; Wilhelm, D, 2023)
"While high-dose prednisolone treatment led to an increased anastomotic leakage rate in mice under colitis, low-dose prednisolone treatment limited preoperative disease activity and did not influence the leakage rate."4.31Perioperative Low-Dose Prednisolone Treatment Has Beneficial Effects on Postoperative Recovery and Anastomotic Healing in a Murine Colitis Model. ( Bauer, J; Buck, A; Clees, Z; Friess, H; Kasajima, A; Neumann, PA; Oertel, R; Reischl, S; Weber, MC; Wilhelm, D, 2023)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Weber, MC1
Bauer, J1
Buck, A1
Clees, Z1
Oertel, R1
Kasajima, A1
Reischl, S1
Wilhelm, D1
Friess, H1
Neumann, PA1
El-Hussuna, A1
Andersen, J1
Bisgaard, T1
Jess, P1
Henriksen, M1
Oehlenschlager, J1
Thorlacius-Ussing, O1
Olaison, G1

Other Studies

2 other studies available for prednisolone and Anastomotic Leak

ArticleYear
Perioperative Low-Dose Prednisolone Treatment Has Beneficial Effects on Postoperative Recovery and Anastomotic Healing in a Murine Colitis Model.
    Journal of Crohn's & colitis, 2023, Jun-16, Volume: 17, Issue:6

    Topics: Anastomosis, Surgical; Anastomotic Leak; Animals; Colitis; Inflammatory Bowel Diseases; Mice; Predni

2023
Biologic treatment or immunomodulation is not associated with postoperative anastomotic complications in abdominal surgery for Crohn's disease.
    Scandinavian journal of gastroenterology, 2012, Volume: 47, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anastomosis, Surgical; Anastomotic Leak; Anti-Inflammato

2012