Page last updated: 2024-11-06

prednisolone and Alexander Disease

prednisolone has been researched along with Alexander Disease in 1 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Alexander Disease: Rare leukoencephalopathy with infantile-onset accumulation of Rosenthal fibers in the subpial, periventricular, and subependymal zones of the brain. Rosenthal fibers are GLIAL FIBRILLARY ACIDIC PROTEIN aggregates found in ASTROCYTES. Juvenile- and adult-onset types show progressive atrophy of the lower brainstem instead. De novo mutations in the GFAP gene are associated with the disease with propensity for paternal inheritance.

Research Excerpts

ExcerptRelevanceReference
" We aimed to determine the potential genetic cause(s) contributing to the AxD type II manifestations in a 9-year-old male who presented area postrema-like syndrome and his vomiting and weight loss improved after taking prednisolone."8.12Symptomatic care of late-onset Alexander disease presenting with area postrema-like syndrome with prednisolone; a case report. ( Ashrafi, MR; Babaei, M; Garshasbi, M; Pak, N; Rasoulinezhad, M; Razmara, E; Tavasoli, AR; Zardadi, S, 2022)
" We aimed to determine the potential genetic cause(s) contributing to the AxD type II manifestations in a 9-year-old male who presented area postrema-like syndrome and his vomiting and weight loss improved after taking prednisolone."4.12Symptomatic care of late-onset Alexander disease presenting with area postrema-like syndrome with prednisolone; a case report. ( Ashrafi, MR; Babaei, M; Garshasbi, M; Pak, N; Rasoulinezhad, M; Razmara, E; Tavasoli, AR; Zardadi, S, 2022)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Zardadi, S1
Razmara, E1
Rasoulinezhad, M1
Babaei, M1
Ashrafi, MR1
Pak, N1
Garshasbi, M1
Tavasoli, AR1

Other Studies

1 other study available for prednisolone and Alexander Disease

ArticleYear
Symptomatic care of late-onset Alexander disease presenting with area postrema-like syndrome with prednisolone; a case report.
    BMC pediatrics, 2022, 07-13, Volume: 22, Issue:1

    Topics: Alexander Disease; Area Postrema; Glial Fibrillary Acidic Protein; Humans; Male; Prednisolone; Seizu

2022