prednisolone and Alcoholic Hepatitis studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Research Excerpts

Excerpt	Relevance	Reference
"Treatment with prednisolone improves the short-term survival of patients with severe biopsy-proved alcoholic hepatitis."	10.17	A randomized trial of prednisolone in patients with severe alcoholic hepatitis. ( Benhamou, JP; Chaput, JC; Mathurin, P; Poynard, T; Ramond, MJ; Rueff, B; Théodore, C, 1992)
"Alcoholic hepatitis (AH) markedly decreases the urea synthesis capacity."	9.27	Time course of compromised urea synthesis in patients with alcoholic hepatitis. ( Aagaard, NK; Glavind, E; Gronbaek, H; Orntoft, NW; Thomsen, KL; Vilstrup, H, 2018)
"Patients with SAH given prednisolone are at greater risk for developing serious infections and infections after treatment than patients not given prednisolone, which may offset its therapeutic benefit."	9.24	In Patients With Severe Alcoholic Hepatitis, Prednisolone Increases Susceptibility to Infection and Infection-Related Mortality, and Is Associated With High Circulating Levels of Bacterial DNA. ( Allison, M; Atkinson, SR; Austin, A; Forrest, EH; Gleeson, D; Knapp, S; Masson, S; Maurice, J; McCune, A; Patch, D; Richardson, P; Ryder, SD; Thursz, MR; Vergis, N; Wright, M, 2017)
"The aim of the clinical effectiveness and cost-effectiveness of STeroids Or Pentoxifylline for Alcoholic Hepatitis trial was to resolve the clinical dilemma on the use of prednisolone or PTX."	9.20	The clinical effectiveness and cost-effectiveness of STeroids Or Pentoxifylline for Alcoholic Hepatitis (STOPAH): a 2 × 2 factorial randomised controlled trial. ( Allison, M; Austin, A; Bowers, M; Day, C; Downs, N; Forrest, E; Gleeson, D; Homer, T; Kirkman, S; Masson, S; McCune, A; Mellor, J; O'Grady, J; Patch, D; Ratcliffe, I; Richardson, P; Roderick, P; Ryder, S; Stanton, L; Ternent, L; Thursz, M; Vale, L; Wright, M, 2015)
"Pentoxifylline did not improve survival in patients with alcoholic hepatitis."	9.20	Prednisolone or pentoxifylline for alcoholic hepatitis. ( Allison, M; Austin, A; Bowers, M; Day, CP; Downs, N; Forrest, EH; Gleeson, D; Grant, A; Hood, S; MacGilchrist, A; Masson, S; McCune, A; Mellor, J; O'Grady, J; Patch, D; Ratcliffe, I; Richardson, P; Roderick, P; Ryder, S; Stanton, L; Thursz, MR; Vergis, N; Wright, M, 2015)
"The findings demonstrate that the efficacy of the pentoxifylline is not statistically equivalent to the efficacy of prednisolone, supporting the use of prednisolone as a preferred treatment option in patients with severe alcoholic hepatitis."	9.19	Pentoxifylline vs. corticosteroid to treat severe alcoholic hepatitis: a randomised, non-inferiority, open trial. ( Baik, SK; Jang, JY; Kim, DJ; Kim, HS; Kim, IH; Kim, SG; Kim, TY; Kim, YS; Lee, HJ; Lee, JS; Park, SH; Park, SY; Sohn, JH; Suh, SJ; Suk, KT; Tak, WY; Um, SH; Yim, HJ; Yoon, KT, 2014)
"In patients with alcoholic hepatitis, 4-week treatment with pentoxifylline and prednisolone, compared with prednisolone alone, did not result in improved 6-month survival."	9.17	Prednisolone with vs without pentoxifylline and survival of patients with severe alcoholic hepatitis: a randomized clinical trial. ( Anty, R; Boursier, J; Canva-Delcambre, V; Carbonell, N; Dao, T; Dharancy, S; Diaz, E; Duhamel, A; Lebrec, D; Louvet, A; Mathurin, P; Moirand, R; Moreno, C; Nahon, P; Naveau, S; Pageaux, GP; Paupard, T; Salleron, J; Silvain, C; Sobesky, R; Talbodec, N; Thabut, D, 2013)
"Although combination therapy with prednisolone plus N-acetylcysteine increased 1-month survival among patients with severe acute alcoholic hepatitis, 6-month survival, the primary outcome, was not improved."	9.15	Glucocorticoids plus N-acetylcysteine in severe alcoholic hepatitis. ( Benferhat, S; Bental, A; Bernard-Chabert, B; Carbonell, N; Chatelain, D; Dewaele, F; Dupas, JL; Ghrib, S; Goria, O; Nguyen-Khac, E; Piquet, MA; Rudler, M; Thevenot, T; Tossou, H; Tramier, B, 2011)
"To compare the efficacy of pentoxifylline and prednisolone in the treatment of severe alcoholic hepatitis, and to evaluate the role of different liver function scores in predicting prognosis."	9.14	Pentoxifylline versus prednisolone for severe alcoholic hepatitis: a randomized controlled trial. ( Baksi, SD; De, BK; Dutta, D; Gangopadhyay, S; Ghosh, P; Pani, A, 2009)
"Whether or not prednisolone (or prednisone) should be used to treat alcoholic hepatitis remains controversial."	9.06	[Treatment of acute alcoholic hepatitis with prednisolone. 45 patients]. ( Bories, P; Guedj, JY; Michel, H; Mirouze, D; Yousfi, A, 1987)
"Twenty-eight patients entered a double-blind controlled trial to evaluate the efficacy of prednisolone treatment in severe acute alcoholic hepatitis accompanied by encephalopathy."	9.05	Double-blind controlled trial of prednisolone therapy in patients with severe acute alcoholic hepatitis and spontaneous encephalopathy. ( Boyer, T; Depew, W; Omata, M; Redeker, A; Reynolds, T, 1980)
"A cooperative study was conducted to determine the efficacy of 30 days of treatment with either a glucocorticosteroid (prednisolone) or an anabolic steroid (oxandrolone) in moderate or severe alcoholic hepatitis."	9.05	Short-term and long-term survival in patients with alcoholic hepatitis treated with oxandrolone and prednisolone. ( Anderson, S; Garcia-Pont, P; Goldberg, S; Kiernan, T; Mendenhall, CL; Seeff, LB; Sorrell, M; Tamburro, C; Weesner, R; Zetterman, R, 1984)
"A previous report from this institution demonstrated significant improvement of caloric intake and survival in patients with alcoholic hepatitis and hepatic encephalopathy given prednisolone when compared with placebo."	9.04	Treatment of alcoholic hepatitis with encephalopathy. Comparison of prednisolone with caloric supplements. ( Bozymski, EM; Fallon, HJ; Lesesne, HR, 1978)
"We performed a meta-analysis of individual patient data from 11 randomized controlled trials comparing corticosteroids, pentoxifylline, or their combination in patients with severe alcoholic hepatitis."	8.98	Corticosteroids Reduce Risk of Death Within 28 Days for Patients With Severe Alcoholic Hepatitis, Compared With Pentoxifylline or Placebo-a Meta-analysis of Individual Data From Controlled Trials. ( Akriviadis, E; Atkinson, SR; Carithers, RL; Duhamel, A; Kim, DJ; Labreuche, J; Louvet, A; Maddrey, WC; Mathurin, P; Morgan, TR; O'Grady, JG; Ramond, MJ; Sidhu, SS; Sinakos, E; Thursz, MR, 2018)
" We present the first study to compare outcomes in patients of severe alcoholic hepatitis (SAH) on nutritional therapy, corticosteroids, pentoxifylline, and healthy donor fecal transplantation (FMT) and discuss distinct microbial community and microbiome metabolic functional changes after FMT."	7.88	Corticosteroids, nutrition, pentoxifylline, or fecal microbiota transplantation for severe alcoholic hepatitis. ( Augustine, P; Ganesan, K; Phadke, N; Philips, CA; Ranade, S, 2018)
"Management of severe alcoholic hepatitis with prednisolone plus SAMe was associated with better therapy response (p = 0."	7.83	Prednisolone plus S-adenosil-L-methionine in severe alcoholic hepatitis. ( Ivashkin, V; Komkova, I; Maevskaya, M; Pavlov, A; Pavlov, C; Tkachenko, P, 2016)
"Prednisolone therapy has shown modest survival benefits over placebo at 28 but not 90 days."	7.30	Fecal microbiota transplantation compared with prednisolone in severe alcoholic hepatitis patients: a randomized trial. ( Arora, V; Dore, J; Jagdish, R; Khillan, V; Kumar, G; Kumar, M; Mondot, S; Pande, A; Rastogi, A; Sarin, SK; Sharma, S; Shasthry, SM; Vijayaraghavan, R, 2023)
"In severe alcoholic hepatitis (AH), 40% of patients will obtain no benefit from corticosteroids."	6.73	Early switch to pentoxifylline in patients with severe alcoholic hepatitis is inefficient in non-responders to corticosteroids. ( Canva, V; Coevoet, H; Deltenre, P; Dharancy, S; Diaz, E; Louvet, A; Mathurin, P; Plane, C; Texier, F; Thévenot, T, 2008)
"Treatment with prednisolone improves the short-term survival of patients with severe biopsy-proved alcoholic hepatitis."	6.17	A randomized trial of prednisolone in patients with severe alcoholic hepatitis. ( Benhamou, JP; Chaput, JC; Mathurin, P; Poynard, T; Ramond, MJ; Rueff, B; Théodore, C, 1992)
"To determine the efficacy of amoxicillin-clavulanate, compared with placebo, on mortality in patients hospitalized with severe alcohol-related hepatitis and treated with prednisolone."	5.69	Effect of Prophylactic Antibiotics on Mortality in Severe Alcohol-Related Hepatitis: A Randomized Clinical Trial. ( Anty, R; Bernard-Chabert, B; Bureau, C; Carbonell, N; Dao, T; Duhamel, A; Hilleret, MN; Labreuche, J; Louvet, A; Mathurin, P; Minello, A; Moirand, R; Nahon, P; Nguyen-Khac, E; Oberti, F; Pageaux, GP; Paupard, T; Potey, C; Thévenot, T; Wartel, F, 2023)
"We identified 37 patients with alcoholic hepatitis with a modified Maddrey's discriminant function of 32 or greater."	5.33	Bilirubin response to corticosteroids in severe alcoholic hepatitis. ( Forrest, EH; Morris, JM, 2005)
"Alcoholic hepatitis (AH) markedly decreases the urea synthesis capacity."	5.27	Time course of compromised urea synthesis in patients with alcoholic hepatitis. ( Aagaard, NK; Glavind, E; Gronbaek, H; Orntoft, NW; Thomsen, KL; Vilstrup, H, 2018)
"Patients with SAH given prednisolone are at greater risk for developing serious infections and infections after treatment than patients not given prednisolone, which may offset its therapeutic benefit."	5.24	In Patients With Severe Alcoholic Hepatitis, Prednisolone Increases Susceptibility to Infection and Infection-Related Mortality, and Is Associated With High Circulating Levels of Bacterial DNA. ( Allison, M; Atkinson, SR; Austin, A; Forrest, EH; Gleeson, D; Knapp, S; Masson, S; Maurice, J; McCune, A; Patch, D; Richardson, P; Ryder, SD; Thursz, MR; Vergis, N; Wright, M, 2017)
"The aim of the clinical effectiveness and cost-effectiveness of STeroids Or Pentoxifylline for Alcoholic Hepatitis trial was to resolve the clinical dilemma on the use of prednisolone or PTX."	5.20	The clinical effectiveness and cost-effectiveness of STeroids Or Pentoxifylline for Alcoholic Hepatitis (STOPAH): a 2 × 2 factorial randomised controlled trial. ( Allison, M; Austin, A; Bowers, M; Day, C; Downs, N; Forrest, E; Gleeson, D; Homer, T; Kirkman, S; Masson, S; McCune, A; Mellor, J; O'Grady, J; Patch, D; Ratcliffe, I; Richardson, P; Roderick, P; Ryder, S; Stanton, L; Ternent, L; Thursz, M; Vale, L; Wright, M, 2015)
"Pentoxifylline did not improve survival in patients with alcoholic hepatitis."	5.20	Prednisolone or pentoxifylline for alcoholic hepatitis. ( Allison, M; Austin, A; Bowers, M; Day, CP; Downs, N; Forrest, EH; Gleeson, D; Grant, A; Hood, S; MacGilchrist, A; Masson, S; McCune, A; Mellor, J; O'Grady, J; Patch, D; Ratcliffe, I; Richardson, P; Roderick, P; Ryder, S; Stanton, L; Thursz, MR; Vergis, N; Wright, M, 2015)
"The findings demonstrate that the efficacy of the pentoxifylline is not statistically equivalent to the efficacy of prednisolone, supporting the use of prednisolone as a preferred treatment option in patients with severe alcoholic hepatitis."	5.19	Pentoxifylline vs. corticosteroid to treat severe alcoholic hepatitis: a randomised, non-inferiority, open trial. ( Baik, SK; Jang, JY; Kim, DJ; Kim, HS; Kim, IH; Kim, SG; Kim, TY; Kim, YS; Lee, HJ; Lee, JS; Park, SH; Park, SY; Sohn, JH; Suh, SJ; Suk, KT; Tak, WY; Um, SH; Yim, HJ; Yoon, KT, 2014)
"In patients with alcoholic hepatitis, 4-week treatment with pentoxifylline and prednisolone, compared with prednisolone alone, did not result in improved 6-month survival."	5.17	Prednisolone with vs without pentoxifylline and survival of patients with severe alcoholic hepatitis: a randomized clinical trial. ( Anty, R; Boursier, J; Canva-Delcambre, V; Carbonell, N; Dao, T; Dharancy, S; Diaz, E; Duhamel, A; Lebrec, D; Louvet, A; Mathurin, P; Moirand, R; Moreno, C; Nahon, P; Naveau, S; Pageaux, GP; Paupard, T; Salleron, J; Silvain, C; Sobesky, R; Talbodec, N; Thabut, D, 2013)
"Although combination therapy with prednisolone plus N-acetylcysteine increased 1-month survival among patients with severe acute alcoholic hepatitis, 6-month survival, the primary outcome, was not improved."	5.15	Glucocorticoids plus N-acetylcysteine in severe alcoholic hepatitis. ( Benferhat, S; Bental, A; Bernard-Chabert, B; Carbonell, N; Chatelain, D; Dewaele, F; Dupas, JL; Ghrib, S; Goria, O; Nguyen-Khac, E; Piquet, MA; Rudler, M; Thevenot, T; Tossou, H; Tramier, B, 2011)
"To compare the efficacy of pentoxifylline and prednisolone in the treatment of severe alcoholic hepatitis, and to evaluate the role of different liver function scores in predicting prognosis."	5.14	Pentoxifylline versus prednisolone for severe alcoholic hepatitis: a randomized controlled trial. ( Baksi, SD; De, BK; Dutta, D; Gangopadhyay, S; Ghosh, P; Pani, A, 2009)
"This study has shown that corticosteroids in the form of prednisolone 30 mg daily are superior to a broad antioxidant cocktail in the treatment of severe alcoholic hepatitis."	5.12	Antioxidants versus corticosteroids in the treatment of severe alcoholic hepatitis--a randomised clinical trial. ( Bomford, A; Curtis, H; Donaldson, N; O'Grady, J; Phillips, M; Portmann, B, 2006)
"Whether or not prednisolone (or prednisone) should be used to treat alcoholic hepatitis remains controversial."	5.06	[Treatment of acute alcoholic hepatitis with prednisolone. 45 patients]. ( Bories, P; Guedj, JY; Michel, H; Mirouze, D; Yousfi, A, 1987)
"A cooperative study was conducted to determine the efficacy of 30 days of treatment with either a glucocorticosteroid (prednisolone) or an anabolic steroid (oxandrolone) in moderate or severe alcoholic hepatitis."	5.05	Short-term and long-term survival in patients with alcoholic hepatitis treated with oxandrolone and prednisolone. ( Anderson, S; Garcia-Pont, P; Goldberg, S; Kiernan, T; Mendenhall, CL; Seeff, LB; Sorrell, M; Tamburro, C; Weesner, R; Zetterman, R, 1984)
"Twenty-eight patients entered a double-blind controlled trial to evaluate the efficacy of prednisolone treatment in severe acute alcoholic hepatitis accompanied by encephalopathy."	5.05	Double-blind controlled trial of prednisolone therapy in patients with severe acute alcoholic hepatitis and spontaneous encephalopathy. ( Boyer, T; Depew, W; Omata, M; Redeker, A; Reynolds, T, 1980)
"A previous report from this institution demonstrated significant improvement of caloric intake and survival in patients with alcoholic hepatitis and hepatic encephalopathy given prednisolone when compared with placebo."	5.04	Treatment of alcoholic hepatitis with encephalopathy. Comparison of prednisolone with caloric supplements. ( Bozymski, EM; Fallon, HJ; Lesesne, HR, 1978)
"Fifty-five patients with alcoholic hepatitis were studied in a 28- to 32-day randomized double blind treatment trial comparing prednisolone (40 mg per day) with placebo therapy."	5.04	Corticosteroid therapy of alcoholic hepatitis. ( Bedine, MS; Boitnott, JK; Maddrey, WC; Mezey, E; Weber, FL; White, RI, 1978)
"We performed a meta-analysis of individual patient data from 11 randomized controlled trials comparing corticosteroids, pentoxifylline, or their combination in patients with severe alcoholic hepatitis."	4.98	Corticosteroids Reduce Risk of Death Within 28 Days for Patients With Severe Alcoholic Hepatitis, Compared With Pentoxifylline or Placebo-a Meta-analysis of Individual Data From Controlled Trials. ( Akriviadis, E; Atkinson, SR; Carithers, RL; Duhamel, A; Kim, DJ; Labreuche, J; Louvet, A; Maddrey, WC; Mathurin, P; Morgan, TR; O'Grady, JG; Ramond, MJ; Sidhu, SS; Sinakos, E; Thursz, MR, 2018)
"Participants in the Steroids or Pentoxifylline for Alcoholic Hepatitis trial with day zero (D0) creatinine available were included."	4.31	In severe alcohol-related hepatitis, acute kidney injury is prevalent, associated with mortality independent of liver disease severity, and can be predicted using IL-8 and micro-RNAs. ( Allison, M; Atkinson, S; Austin, A; Dear, JW; Forrest, E; Hunter, RW; Liu, T; Lord, E; Masson, S; Nunes, J; Richardson, P; Ryder, SD; Thursz, M; Tyson, LD; Vergis, N; Wright, M, 2023)
" We present the first study to compare outcomes in patients of severe alcoholic hepatitis (SAH) on nutritional therapy, corticosteroids, pentoxifylline, and healthy donor fecal transplantation (FMT) and discuss distinct microbial community and microbiome metabolic functional changes after FMT."	3.88	Corticosteroids, nutrition, pentoxifylline, or fecal microbiota transplantation for severe alcoholic hepatitis. ( Augustine, P; Ganesan, K; Phadke, N; Philips, CA; Ranade, S, 2018)
"Prednisolone therapy increases the risk of infections in patients with severe alcoholic hepatitis (SAH)."	3.85	A Day-4 Lille Model Predicts Response to Corticosteroids and Mortality in Severe Alcoholic Hepatitis. ( Altamirano, J; Bataller, R; Becerra-Martins-de-Oliveira, B; Caballeria, J; Chavez-Araujo, R; de Lourdes Candolo-Martinelli, A; Duarte-Rojo, A; Duvoor, C; Fernandez-de-Almeida, S; Garcia-Saenz-de-Sicilia, M; Holanda-Almeida, P; Prado, V, 2017)
"Management of severe alcoholic hepatitis with prednisolone plus SAMe was associated with better therapy response (p = 0."	3.83	Prednisolone plus S-adenosil-L-methionine in severe alcoholic hepatitis. ( Ivashkin, V; Komkova, I; Maevskaya, M; Pavlov, A; Pavlov, C; Tkachenko, P, 2016)
" This study aimed to elucidate the contribution of GILZ to the pathogenesis of alcoholic hepatitis (AH): we (1) assessed GILZ expression in the livers of patients with AH and (2) treated patients with severe AH with GCs (prednisolone 40 mg/day) and studied the effect of GILZ modulation on circulating monocyte function."	3.74	Glucocorticoid-induced leucine zipper: A key protein in the sensitization of monocytes to lipopolysaccharide in alcoholic hepatitis. ( Balian, A; Bigorgne, A; Bouchet-Delbos, L; Cassard-Doulcier, AM; Delaveaucoupet, J; Durand-Gasselin, I; Emilie, D; Hamdi, H; Maillot, MC; Naveau, S; Perlemuter, G; Prévot, S, 2007)
"Prednisolone therapy has shown modest survival benefits over placebo at 28 but not 90 days."	3.30	Fecal microbiota transplantation compared with prednisolone in severe alcoholic hepatitis patients: a randomized trial. ( Arora, V; Dore, J; Jagdish, R; Khillan, V; Kumar, G; Kumar, M; Mondot, S; Pande, A; Rastogi, A; Sarin, SK; Sharma, S; Shasthry, SM; Vijayaraghavan, R, 2023)
"In severe alcoholic hepatitis, prednisolone is indicated as the first-line treatment even with the possibility of various complications."	3.01	Current and future treatment for alcoholic-related liver diseases. ( Kim, W; Yoon, EL, 2023)
"Severe alcoholic hepatitis (SAH) is often a progressive disease with high mortality and limited steroid responsiveness."	2.90	Efficacy of Granulocyte Colony-stimulating Factor in the Management of Steroid-Nonresponsive Severe Alcoholic Hepatitis: A Double-Blind Randomized Controlled Trial. ( Pande, A; Sarin, SK; Sharma, MK; Shasthry, SM; Shasthry, V, 2019)
"Severe alcoholic hepatitis (AH) is a life-threatening condition lacking good serologic markers to tailor treatment and predict recovery."	2.87	Noncholesterol Sterols as Surrogate Markers in Patients with Severe Alcoholic Hepatitis. ( Färkkilä, M; Nissinen, M; Sahlman, P; Simonen, P, 2018)
"In severe alcoholic hepatitis (AH), 40% of patients will obtain no benefit from corticosteroids."	2.73	Early switch to pentoxifylline in patients with severe alcoholic hepatitis is inefficient in non-responders to corticosteroids. ( Canva, V; Coevoet, H; Deltenre, P; Dharancy, S; Diaz, E; Louvet, A; Mathurin, P; Plane, C; Texier, F; Thévenot, T, 2008)
"For prednisolone, the response was seen only when the DF was 81-100 reducing mortality 45% When oxandrolone, an androgenic anabolic steroid treatment was given, efficacy was observed only in those with moderate malnutrition (PCM score 60-79% of normal) and maximized with adequate caloric intake reducing mortality 86%."	2.68	Relationship of protein calorie malnutrition to alcoholic liver disease: a reexamination of data from two Veterans Administration Cooperative Studies. ( Gartside, P; Mendenhall, C; Moritz, T; Roselle, GA, 1995)
"Corticosteroid therapy for the treatment of alcoholic hepatitis was evaluated in nine short-term randomized clinical trials that included 150 treated and 161 control patients with a mortality rate of 37 and 44%, respectively."	2.65	Use of colchicine and steroids in the treatment of alcoholic liver disease. ( Galambos, JT; Riepe, SP, 1984)
"The short-term prognosis of acute alcoholic hepatitis depends on liver recovery, and ranges widely from rapid improvement to grim multiorgan failure despite treatment."	2.61	Acute Alcoholic Hepatitis. ( Im, GY, 2019)
"Autoimmune hepatitis is a rare cause of hepatitis in HIV-infected individuals; however, this condition has been increasingly reported over the past few years."	2.61	Autoimmune hepatitis in human immunodeficiency virus-infected patients: A case series and review of the literature. ( Avihingsanon, A; Chaiteerakij, R; Sanpawat, A; Treeprasertsuk, S, 2019)
"Severe alcoholic hepatitis (SAH) is defined by modified Maddrey discriminant function ≥32 or Model for End-Stage Liver Disease (MELD) >21 and/or hepatic encephalopathy."	2.55	New paradigms in management of alcoholic hepatitis: a review. ( Goyal, O; Kishore, H; Sidhu, S; Sidhu, SS, 2017)
"Prednisolone has become the principal agent for treating patients with severe AH."	2.53	Acute Alcoholic Hepatitis: Therapy. ( Lucey, MR; Phillips, PK, 2016)
"Severe alcoholic hepatitis is a clinically-diagnosed condition associated with significant mortality."	2.45	Review article: the diagnosis and management of alcoholic hepatitis. ( Ahn, J; Cohen, SM, 2009)
"Treatment with propylthiouracil and insulin and glucagon infusions has also shown promising results in controlled studies but there is still no general agreement on their value."	2.38	Treatment of advanced alcoholic liver disease. ( Bird, GL; Williams, R, 1990)
"Up to 40% of patients with severe alcoholic hepatitis (AH) die within 6 months of presentation, making prompt diagnosis and appropriate treatment essential."	1.56	In Severe Alcoholic Hepatitis, Serum Keratin-18 Fragments Are Diagnostic, Prognostic, and Theragnostic Biomarkers. ( Aithal, GP; Astbury, S; Atkinson, SR; Bantel, H; Goldin, R; Grove, JI; Guha, IN; Liebig, S; Newcombe, P; Quaglia, A; Strnad, P; Thursz, MR; Vergis, N, 2020)
"The NLR is associated with AKI and infection in severe alcoholic hepatitis."	1.51	Baseline neutrophil-to-lymphocyte ratio predicts response to corticosteroids and is associated with infection and renal dysfunction in alcoholic hepatitis. ( Allison, M; Atkinson, SR; Austin, A; Dhanda, A; Forrest, EH; Fraser, A; Hayes, PC; Katarey, D; Masson, S; McCune, A; Parker, R; Potts, J; Richardson, P; Ryder, S; Sinha, R; Storey, N; Thursz, MR; Vergis, N; Verma, S, 2019)
"Infections frequently complicate severe alcoholic hepatitis and affect survival."	1.43	Infections complicating severe alcoholic hepatitis: Enterococcus species represent the most frequently identified pathogen. ( Beisel, C; Benten, D; Blessin, U; Kluwe, J; Lohse, AW; Schulze Zur Wiesch, J; Wehmeyer, MH, 2016)
"All trials on severe alcoholic hepatitis (AH) have included patients with "pure" AH, i."	1.42	Prognosis of treated severe alcoholic hepatitis in patients with gastrointestinal bleeding. ( Benosman, H; Capocci, R; Charlotte, F; Lebray, P; Mouri, S; Poynard, T; Rudler, M; Thabut, D, 2015)
"We made a final diagnosis of alcoholic hepatitis and successfully treated him with corticosteroids."	1.38	[A case of alcoholic hepatitis diagnosed by a liver biopsy and successfully treated by corticosteroid therapy]. ( Kobayashi, K; Seshimo, K; Shibagaki, K; Taniguchi, H, 2012)
"Steroids improve the outcome in alcoholic hepatitis (AH), but up to 40% of patients fail to respond adequately."	1.37	In vitro steroid resistance correlates with outcome in severe alcoholic hepatitis. ( Collins, P; Dayan, CM; di Mambro, AJ; Gordon, F; McCune, A; Parker, R, 2011)
"We identified 37 patients with alcoholic hepatitis with a modified Maddrey's discriminant function of 32 or greater."	1.33	Bilirubin response to corticosteroids in severe alcoholic hepatitis. ( Forrest, EH; Morris, JM, 2005)
"Prednisolone was effective in the short term but resulted in an increase in C-reactive protein (CRP), peripheral leukocytes, and serum total bilirubin."	1.32	Severe alcoholic hepatitis successfully treated by leukocytapheresis: a case report. ( Abe, H; Arinaga, T; Ide, T; Ishii, K; Koga, Y; Kumashiro, R; Ogata, K; Ono, N; Sakamoto, Y; Sata, M; Tanabe, R; Tanaka, E; Tsuji, Y, 2003)
"Thirteen patients with severe alcoholic hepatitis were treated with systemic steroids and TEN."	1.32	Combining steroids with enteral nutrition: a better therapeutic strategy for severe alcoholic hepatitis? Results of a pilot study. ( Alvarez, MA; Cabré, E; Gassull, MA; Lorenzo-Zúñiga, V; Montoliu, S; Planas, R, 2004)
"In cirrhotic patients with severe acute alcoholic hepatitis, the TNFsRp75/TNFsRp55 ratio was significantly lower than in all other groups."	1.30	Plasma levels of soluble tumor necrosis factor receptors p55 and p75 in patients with alcoholic liver disease of increasing severity. ( Balian, A; Borotto, E; Capron, F; Chaput, JC; Emilie, D; Galanaud, P; Giraud, V; Grangeot-Keros, L; Naveau, S; Portier, A, 1998)
"In human studies of patients with alcoholic hepatitis, these abnormalities were also seen with specific correlation with protein malnutrition."	1.29	Alcohol modulation of immune function: clinical and experimental data. Veterans Affairs Cooperative Study Groups 119 and 275. ( Chedid, A; Gartside, P; Mendenhall, CL; Moritz, TE; Roselle, GA, 1995)
"Treatment with prednisolone should be given for at least two years, with adjustment of dosage according to the serum levels of aspartate transaminase; maintenance does should be 8-12 mg a day."	1.27	Treatment of chronic active hepatitis and other liver diseases with corticosteroid agents. ( Mackay, IR, 1987)

Timeframe	Studies, this research(%)	All Research%
pre-1990	14 (15.38)	18.7374
1990's	11 (12.09)	18.2507
2000's	14 (15.38)	29.6817
2010's	45 (49.45)	24.3611
2020's	7 (7.69)	2.80

Trial	Phase	Enrollment	Study Type	Start Date	Status
Efficacy and Safety of Granulocyte-colony Stimulating Factor in Patients With Severe Alcoholic Hepatitis With Null or Partial Response to Steroid: A Randomized, Double-blind, Placebo-controlled, Nationwide Multi-center Study[NCT02442180]	Phase 3	64 participants (Actual)	Interventional	2015-07-31	Terminated (stopped due to failure to recruit eligible patients)
Efficacy of G-CSF in the Management of Steroid Non-responsive Severe Alcoholic Hepatitis. - A Double Blind Randomized Control Trial.[NCT01820208]		28 participants (Actual)	Interventional	2014-03-01	Completed
Evaluation of the Efficacy of an Antibiotic Combined With Standard Treatment in Severe Alcoholic Hepatitis[NCT02281929]	Phase 3	297 participants (Actual)	Interventional	2015-06-13	Completed
Evaluation of the Survival Benefit of the Adjunction of Pentoxifylline to Corticosteroids in Patients Suffering From Severe Alcoholic Hepatitis[NCT01214226]	Phase 3	278 participants (Actual)	Interventional	2007-12-31	Completed
Effect of Omega-5 Fatty Acid Supplement on Markers of Inflammation and Oxidative Stress in Patients With Severe Alcoholic Hepatitis Treated With Prednisone[NCT03732586]		40 participants (Actual)	Interventional	2018-09-30	Completed
U01 Pilot Trial of DUR-928 in Patients With Moderate and Severe Alcoholic Hepatitis[NCT03917407]	Phase 2	43 participants (Actual)	Interventional	2021-06-01	Completed
Digoxin In Treatment of Alcohol Associated Hepatitis (DIGIT-AlcHep)[NCT05014087]	Phase 2	60 participants (Anticipated)	Interventional	2021-10-08	Recruiting
Corticosteroids in Severe Alcoholic Hepatitis Patients With Early Spontaneous Improvement[NCT03160651]		140 participants (Anticipated)	Interventional	2018-02-09	Recruiting
The Effects of Dexamethasone Administration on Jaundice Following Liver Resection: a Randomized Controlled Trial[NCT02991339]	Phase 2/Phase 3	76 participants (Actual)	Interventional	2016-06-30	Completed
The Mechanism of Action of N-acetylcysteine for Reducing the Risk of Infection in Alcoholic Hepatitis[NCT03069300]	Phase 3	42 participants (Anticipated)	Interventional	2015-10-01	Recruiting
Comparison of Bovine Colostrum Versus Placebo in Treatment of Severe Alcoholic Hepatitis: A Randomized Double Blind Controlled Trial[NCT02473341]	Phase 3	174 participants (Actual)	Interventional	2017-11-14	Active, not recruiting
Treatment of Acute Severe Alcoholic Hepatitis With Corticoids Plus N Acetyl Cysteine Versus Corticoids Alone: a French Multicentre Randomized Controlled Study.[NCT00863785]	Phase 3	174 participants (Actual)	Interventional	2004-04-30	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
Current and future treatment for alcoholic-related liver diseases. Journal of gastroenterology and hepatology, 2023, Volume: 38, Issue:8 Topics: Hepatitis, Alcoholic; Humans; Inflammation; Liver Diseases, Alcoholic; Liver Transplantation; Predni	2023
Autoimmune hepatitis in human immunodeficiency virus-infected patients: A case series and review of the literature. World journal of gastroenterology, 2019, Sep-21, Volume: 25, Issue:35 Topics: Adult; Alanine Transaminase; Anti-HIV Agents; Antibodies, Antinuclear; Aspartate Aminotransferases;	2019
Corticosteroids Reduce Risk of Death Within 28 Days for Patients With Severe Alcoholic Hepatitis, Compared With Pentoxifylline or Placebo-a Meta-analysis of Individual Data From Controlled Trials. Gastroenterology, 2018, Volume: 155, Issue:2 Topics: Drug Therapy, Combination; Glucocorticoids; Hepatitis, Alcoholic; Humans; Pentoxifylline; Placebos;	2018
Acute Alcoholic Hepatitis. Clinics in liver disease, 2019, Volume: 23, Issue:1 Topics: Acute Disease; Alanine Transaminase; Aspartate Aminotransferases; Biopsy; Elasticity Imaging Techniq	2019
Alcoholic hepatitis: Prognosis and treatment. Gastroenterologia y hepatologia, 2014, Volume: 37, Issue:4 Topics: Alcohol Deterrents; Animals; Antibodies, Monoclonal; Disease Models, Animal; Etanercept; Fatty Liver	2014
Treatment of Severe Alcoholic Hepatitis. Gastroenterology, 2016, Volume: 150, Issue:8 Topics: Acetylcysteine; Biopsy; Free Radical Scavengers; Glucocorticoids; Hepatitis, Alcoholic; Humans; Live	2016
Acute Alcoholic Hepatitis: Therapy. Clinics in liver disease, 2016, Volume: 20, Issue:3 Topics: Acute Disease; Alcohol Abstinence; Antioxidants; Glucocorticoids; Hepatitis, Alcoholic; Humans; Live	2016
New paradigms in management of alcoholic hepatitis: a review. Hepatology international, 2017, Volume: 11, Issue:3 Topics: Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents; Fecal Microbiota Transplantation; Female	2017
Review article: the diagnosis and management of alcoholic hepatitis. Alimentary pharmacology & therapeutics, 2009, Volume: 30, Issue:1 Topics: Anabolic Agents; Anti-Inflammatory Agents; Antioxidants; Hepatitis, Alcoholic; Humans; Liver Transpl	2009
Alcoholic hepatitis 2010: a clinician's guide to diagnosis and therapy. World journal of gastroenterology, 2010, Oct-21, Volume: 16, Issue:39 Topics: Alcohol Deterrents; Alcohol Drinking; Anti-Inflammatory Agents; Baclofen; Combined Modality Therapy;	2010
A randomized trial of prednisolone in patients with severe alcoholic hepatitis. The New England journal of medicine, 1992, Feb-20, Volume: 326, Issue:8 Topics: Double-Blind Method; Female; Follow-Up Studies; Hepatic Encephalopathy; Hepatitis, Alcoholic; Humans	1992
[Corticoid therapy in the treatment of acute alcoholic hepatitis. Results of a meta-analysis]. Gastroenterologie clinique et biologique, 1991, Volume: 15, Issue:3 Topics: Acute Disease; Hepatitis, Alcoholic; Humans; Meta-Analysis as Topic; Methylprednisolone; Prednisolon	1991
Treatment of advanced alcoholic liver disease. Alcohol and alcoholism (Oxford, Oxfordshire), 1990, Volume: 25, Issue:2-3 Topics: Amino Acids; Anabolic Agents; Colchicine; Combined Modality Therapy; Hepatic Encephalopathy; Hepatit	1990
Treatment of alcoholic hepatitis. The American journal of gastroenterology, 1989, Volume: 84, Issue:10 Topics: Adult; Biopsy; Female; Food, Formulated; Hepatitis, Alcoholic; Humans; Liver; Oxandrolone; Parentera	1989

Article	Year
Fecal microbiota transplantation compared with prednisolone in severe alcoholic hepatitis patients: a randomized trial. Hepatology international, 2023, Volume: 17, Issue:1 Topics: Fecal Microbiota Transplantation; Hepatitis, Alcoholic; Humans; Microbiota; Prednisolone; Treatment	2023
Fecal microbiota transplantation compared with prednisolone in severe alcoholic hepatitis patients: a randomized trial. Hepatology international, 2023, Volume: 17, Issue:1 Topics: Fecal Microbiota Transplantation; Hepatitis, Alcoholic; Humans; Microbiota; Prednisolone; Treatment	2023
Fecal microbiota transplantation compared with prednisolone in severe alcoholic hepatitis patients: a randomized trial. Hepatology international, 2023, Volume: 17, Issue:1 Topics: Fecal Microbiota Transplantation; Hepatitis, Alcoholic; Humans; Microbiota; Prednisolone; Treatment	2023
Fecal microbiota transplantation compared with prednisolone in severe alcoholic hepatitis patients: a randomized trial. Hepatology international, 2023, Volume: 17, Issue:1 Topics: Fecal Microbiota Transplantation; Hepatitis, Alcoholic; Humans; Microbiota; Prednisolone; Treatment	2023
Effect of Prophylactic Antibiotics on Mortality in Severe Alcohol-Related Hepatitis: A Randomized Clinical Trial. JAMA, 2023, 05-09, Volume: 329, Issue:18 Topics: Adult; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Anti-Inflammatory Agent	2023
Time course of compromised urea synthesis in patients with alcoholic hepatitis. Scandinavian journal of gastroenterology, 2018, Volume: 53, Issue:5 Topics: Adult; Blood Glucose; Denmark; Female; Glucagon; Glucocorticoids; Hepatitis, Alcoholic; Humans; Insu	2018
Histological activity score on baseline liver biopsy can predict non-response to steroids in patients with severe alcoholic hepatitis. Virchows Archiv : an international journal of pathology, 2018, Volume: 472, Issue:4 Topics: Adult; Anti-Inflammatory Agents; Biopsy; Drug Resistance; Glucocorticoids; Hepatitis, Alcoholic; Hum	2018
Noncholesterol Sterols as Surrogate Markers in Patients with Severe Alcoholic Hepatitis. Lipids, 2018, Volume: 53, Issue:3 Topics: Adult; Aged; Anti-Inflammatory Agents; Biomarkers; Cholangitis, Sclerosing; Cholestanol; Cholesterol	2018
Efficacy of granulocyte colony stimulating factor in patients with severe alcoholic hepatitis with partial or null response to steroid (GRACIAH trial): study protocol for a randomized controlled trial. Trials, 2018, Dec-22, Volume: 19, Issue:1 Topics: Adrenal Cortex Hormones; Adult; Aged; Double-Blind Method; Drug Administration Schedule; Drug Resist	2018
Efficacy of Granulocyte Colony-stimulating Factor in the Management of Steroid-Nonresponsive Severe Alcoholic Hepatitis: A Double-Blind Randomized Controlled Trial. Hepatology (Baltimore, Md.), 2019, Volume: 70, Issue:3 Topics: Adult; Analysis of Variance; Biopsy, Needle; Disease Progression; Dose-Response Relationship, Drug;	2019
Prednisolone with vs without pentoxifylline and survival of patients with severe alcoholic hepatitis: a randomized clinical trial. JAMA, 2013, Sep-11, Volume: 310, Issue:10 Topics: Double-Blind Method; Drug Therapy, Combination; Female; Free Radical Scavengers; Glucocorticoids; He	2013
Prednisolone with vs without pentoxifylline and survival of patients with severe alcoholic hepatitis: a randomized clinical trial. JAMA, 2013, Sep-11, Volume: 310, Issue:10 Topics: Double-Blind Method; Drug Therapy, Combination; Female; Free Radical Scavengers; Glucocorticoids; He	2013
Prednisolone with vs without pentoxifylline and survival of patients with severe alcoholic hepatitis: a randomized clinical trial. JAMA, 2013, Sep-11, Volume: 310, Issue:10 Topics: Double-Blind Method; Drug Therapy, Combination; Female; Free Radical Scavengers; Glucocorticoids; He	2013
Prednisolone with vs without pentoxifylline and survival of patients with severe alcoholic hepatitis: a randomized clinical trial. JAMA, 2013, Sep-11, Volume: 310, Issue:10 Topics: Double-Blind Method; Drug Therapy, Combination; Female; Free Radical Scavengers; Glucocorticoids; He	2013
Pentoxifylline vs. corticosteroid to treat severe alcoholic hepatitis: a randomised, non-inferiority, open trial. Journal of hepatology, 2014, Volume: 61, Issue:4 Topics: Adult; Anti-Inflammatory Agents; Drug Monitoring; Female; Gastrointestinal Hemorrhage; Hepatitis, Al	2014
Prednisolone or pentoxifylline for alcoholic hepatitis. The New England journal of medicine, 2015, Apr-23, Volume: 372, Issue:17 Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Glucocorticoids; Hepatitis, Alcoholic; Hum	2015
Prednisolone or pentoxifylline for alcoholic hepatitis. The New England journal of medicine, 2015, Apr-23, Volume: 372, Issue:17 Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Glucocorticoids; Hepatitis, Alcoholic; Hum	2015
Prednisolone or pentoxifylline for alcoholic hepatitis. The New England journal of medicine, 2015, Apr-23, Volume: 372, Issue:17 Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Glucocorticoids; Hepatitis, Alcoholic; Hum	2015
Prednisolone or pentoxifylline for alcoholic hepatitis. The New England journal of medicine, 2015, Apr-23, Volume: 372, Issue:17 Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Glucocorticoids; Hepatitis, Alcoholic; Hum	2015
Prednisolone or pentoxifylline for alcoholic hepatitis. The New England journal of medicine, 2015, Apr-23, Volume: 372, Issue:17 Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Glucocorticoids; Hepatitis, Alcoholic; Hum	2015
Prednisolone or pentoxifylline for alcoholic hepatitis. The New England journal of medicine, 2015, Apr-23, Volume: 372, Issue:17 Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Glucocorticoids; Hepatitis, Alcoholic; Hum	2015
Prednisolone or pentoxifylline for alcoholic hepatitis. The New England journal of medicine, 2015, Apr-23, Volume: 372, Issue:17 Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Glucocorticoids; Hepatitis, Alcoholic; Hum	2015
Prednisolone or pentoxifylline for alcoholic hepatitis. The New England journal of medicine, 2015, Apr-23, Volume: 372, Issue:17 Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Glucocorticoids; Hepatitis, Alcoholic; Hum	2015
Prednisolone or pentoxifylline for alcoholic hepatitis. The New England journal of medicine, 2015, Apr-23, Volume: 372, Issue:17 Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Glucocorticoids; Hepatitis, Alcoholic; Hum	2015
Prednisolone or pentoxifylline for alcoholic hepatitis. The New England journal of medicine, 2015, Apr-23, Volume: 372, Issue:17 Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Glucocorticoids; Hepatitis, Alcoholic; Hum	2015
Prednisolone or pentoxifylline for alcoholic hepatitis. The New England journal of medicine, 2015, Apr-23, Volume: 372, Issue:17 Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Glucocorticoids; Hepatitis, Alcoholic; Hum	2015
Prednisolone or pentoxifylline for alcoholic hepatitis. The New England journal of medicine, 2015, Apr-23, Volume: 372, Issue:17 Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Glucocorticoids; Hepatitis, Alcoholic; Hum	2015
Prednisolone or pentoxifylline for alcoholic hepatitis. The New England journal of medicine, 2015, Apr-23, Volume: 372, Issue:17 Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Glucocorticoids; Hepatitis, Alcoholic; Hum	2015
Prednisolone or pentoxifylline for alcoholic hepatitis. The New England journal of medicine, 2015, Apr-23, Volume: 372, Issue:17 Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Glucocorticoids; Hepatitis, Alcoholic; Hum	2015
Prednisolone or pentoxifylline for alcoholic hepatitis. The New England journal of medicine, 2015, Apr-23, Volume: 372, Issue:17 Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Glucocorticoids; Hepatitis, Alcoholic; Hum	2015
Prednisolone or pentoxifylline for alcoholic hepatitis. The New England journal of medicine, 2015, Apr-23, Volume: 372, Issue:17 Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Glucocorticoids; Hepatitis, Alcoholic; Hum	2015
The clinical effectiveness and cost-effectiveness of STeroids Or Pentoxifylline for Alcoholic Hepatitis (STOPAH): a 2 × 2 factorial randomised controlled trial. Health technology assessment (Winchester, England), 2015, Volume: 19, Issue:102 Topics: Adult; Aged; Alcohol Drinking; Cost-Benefit Analysis; Double-Blind Method; Female; Glucocorticoids;	2015
In Patients With Severe Alcoholic Hepatitis, Prednisolone Increases Susceptibility to Infection and Infection-Related Mortality, and Is Associated With High Circulating Levels of Bacterial DNA. Gastroenterology, 2017, Volume: 152, Issue:5 Topics: Adult; Anti-Bacterial Agents; Disease Susceptibility; DNA, Bacterial; Double-Blind Method; Female; F	2017
Pentoxifylline versus prednisolone for severe alcoholic hepatitis: a randomized controlled trial. World journal of gastroenterology, 2009, Apr-07, Volume: 15, Issue:13 Topics: Adult; Aged; Anti-Inflammatory Agents; Double-Blind Method; Female; Hepatitis, Alcoholic; Humans; Ma	2009
Glucocorticoids plus N-acetylcysteine in severe alcoholic hepatitis. The New England journal of medicine, 2011, Nov-10, Volume: 365, Issue:19 Topics: Acetylcysteine; Antioxidants; Bilirubin; Cause of Death; Drug Therapy, Combination; Female; Glucocor	2011
Glucocorticoids plus N-acetylcysteine in severe alcoholic hepatitis. The New England journal of medicine, 2011, Nov-10, Volume: 365, Issue:19 Topics: Acetylcysteine; Antioxidants; Bilirubin; Cause of Death; Drug Therapy, Combination; Female; Glucocor	2011
Glucocorticoids plus N-acetylcysteine in severe alcoholic hepatitis. The New England journal of medicine, 2011, Nov-10, Volume: 365, Issue:19 Topics: Acetylcysteine; Antioxidants; Bilirubin; Cause of Death; Drug Therapy, Combination; Female; Glucocor	2011
Glucocorticoids plus N-acetylcysteine in severe alcoholic hepatitis. The New England journal of medicine, 2011, Nov-10, Volume: 365, Issue:19 Topics: Acetylcysteine; Antioxidants; Bilirubin; Cause of Death; Drug Therapy, Combination; Female; Glucocor	2011
Glucocorticoids plus N-acetylcysteine in severe alcoholic hepatitis. The New England journal of medicine, 2011, Nov-10, Volume: 365, Issue:19 Topics: Acetylcysteine; Antioxidants; Bilirubin; Cause of Death; Drug Therapy, Combination; Female; Glucocor	2011
Glucocorticoids plus N-acetylcysteine in severe alcoholic hepatitis. The New England journal of medicine, 2011, Nov-10, Volume: 365, Issue:19 Topics: Acetylcysteine; Antioxidants; Bilirubin; Cause of Death; Drug Therapy, Combination; Female; Glucocor	2011
Glucocorticoids plus N-acetylcysteine in severe alcoholic hepatitis. The New England journal of medicine, 2011, Nov-10, Volume: 365, Issue:19 Topics: Acetylcysteine; Antioxidants; Bilirubin; Cause of Death; Drug Therapy, Combination; Female; Glucocor	2011
Glucocorticoids plus N-acetylcysteine in severe alcoholic hepatitis. The New England journal of medicine, 2011, Nov-10, Volume: 365, Issue:19 Topics: Acetylcysteine; Antioxidants; Bilirubin; Cause of Death; Drug Therapy, Combination; Female; Glucocor	2011
Glucocorticoids plus N-acetylcysteine in severe alcoholic hepatitis. The New England journal of medicine, 2011, Nov-10, Volume: 365, Issue:19 Topics: Acetylcysteine; Antioxidants; Bilirubin; Cause of Death; Drug Therapy, Combination; Female; Glucocor	2011
Glucocorticoids plus N-acetylcysteine in severe alcoholic hepatitis. The New England journal of medicine, 2011, Nov-10, Volume: 365, Issue:19 Topics: Acetylcysteine; Antioxidants; Bilirubin; Cause of Death; Drug Therapy, Combination; Female; Glucocor	2011
Glucocorticoids plus N-acetylcysteine in severe alcoholic hepatitis. The New England journal of medicine, 2011, Nov-10, Volume: 365, Issue:19 Topics: Acetylcysteine; Antioxidants; Bilirubin; Cause of Death; Drug Therapy, Combination; Female; Glucocor	2011
Glucocorticoids plus N-acetylcysteine in severe alcoholic hepatitis. The New England journal of medicine, 2011, Nov-10, Volume: 365, Issue:19 Topics: Acetylcysteine; Antioxidants; Bilirubin; Cause of Death; Drug Therapy, Combination; Female; Glucocor	2011
Glucocorticoids plus N-acetylcysteine in severe alcoholic hepatitis. The New England journal of medicine, 2011, Nov-10, Volume: 365, Issue:19 Topics: Acetylcysteine; Antioxidants; Bilirubin; Cause of Death; Drug Therapy, Combination; Female; Glucocor	2011
Glucocorticoids plus N-acetylcysteine in severe alcoholic hepatitis. The New England journal of medicine, 2011, Nov-10, Volume: 365, Issue:19 Topics: Acetylcysteine; Antioxidants; Bilirubin; Cause of Death; Drug Therapy, Combination; Female; Glucocor	2011
Glucocorticoids plus N-acetylcysteine in severe alcoholic hepatitis. The New England journal of medicine, 2011, Nov-10, Volume: 365, Issue:19 Topics: Acetylcysteine; Antioxidants; Bilirubin; Cause of Death; Drug Therapy, Combination; Female; Glucocor	2011
Glucocorticoids plus N-acetylcysteine in severe alcoholic hepatitis. The New England journal of medicine, 2011, Nov-10, Volume: 365, Issue:19 Topics: Acetylcysteine; Antioxidants; Bilirubin; Cause of Death; Drug Therapy, Combination; Female; Glucocor	2011
A double-blind randomized controlled trial of infliximab associated with prednisolone in acute alcoholic hepatitis. Hepatology (Baltimore, Md.), 2004, Volume: 39, Issue:5 Topics: Acute Disease; Adult; Anti-Inflammatory Agents; Antibodies, Monoclonal; Double-Blind Method; Drug Th	2004
Antioxidants versus corticosteroids in the treatment of severe alcoholic hepatitis--a randomised clinical trial. Journal of hepatology, 2006, Volume: 44, Issue:4 Topics: Adrenal Cortex Hormones; Adult; Aged; Antioxidants; Confidence Intervals; Female; Glucocorticoids; H	2006
Early switch to pentoxifylline in patients with severe alcoholic hepatitis is inefficient in non-responders to corticosteroids. Journal of hepatology, 2008, Volume: 48, Issue:3 Topics: Adrenal Cortex Hormones; Adult; Aged; Bilirubin; Cohort Studies; Creatinine; Drug Resistance; Female	2008
Use of colchicine and steroids in the treatment of alcoholic liver disease. Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism, 1984, Volume: 2 Topics: Clinical Trials as Topic; Colchicine; Combined Modality Therapy; Double-Blind Method; Energy Intake;	1984
Short-term and long-term survival in patients with alcoholic hepatitis treated with oxandrolone and prednisolone. The New England journal of medicine, 1984, Dec-06, Volume: 311, Issue:23 Topics: Clinical Trials as Topic; Follow-Up Studies; Hepatitis, Alcoholic; Humans; Liver; Middle Aged; Oxand	1984
Therapeutic effect of (+)-cyanidanol-3 in toxic alcoholic liver disease and in chronic active hepatitis. Acta physiologica Hungarica, 1984, Volume: 64, Issue:3-4 Topics: Adult; Aged; Benzopyrans; Catechin; Clinical Trials as Topic; Drug Therapy, Combination; Hepatitis,	1984
Double-blind controlled trial of prednisolone therapy in patients with severe acute alcoholic hepatitis and spontaneous encephalopathy. Gastroenterology, 1980, Volume: 78, Issue:3 Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Hepatic Encephalopathy; Hepatiti	1980
Relationship of protein calorie malnutrition to alcoholic liver disease: a reexamination of data from two Veterans Administration Cooperative Studies. Alcoholism, clinical and experimental research, 1995, Volume: 19, Issue:3 Topics: Adult; Aged; Bilirubin; Creatinine; Double-Blind Method; Hepatitis, Alcoholic; Humans; Liver Functio	1995
Survival and prognostic factors in patients with severe alcoholic hepatitis treated with prednisolone. Gastroenterology, 1996, Volume: 110, Issue:6 Topics: Female; Hepatitis, Alcoholic; Humans; Leukocyte Count; Liver; Male; Middle Aged; Models, Theoretical	1996
Treatment of alcoholic hepatitis with encephalopathy. Comparison of prednisolone with caloric supplements. Gastroenterology, 1978, Volume: 74, Issue:2 Pt 1 Topics: Adult; Clinical Trials as Topic; Energy Intake; Female; Glucose; Hepatic Encephalopathy; Hepatitis,	1978
Corticosteroid therapy of alcoholic hepatitis. Gastroenterology, 1978, Volume: 75, Issue:2 Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Female; Hepatitis, Alcoholic; Humans; Male; Pl	1978
Corticosteroid therapy of alcoholic hepatitis. Gastroenterology, 1978, Volume: 75, Issue:2 Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Female; Hepatitis, Alcoholic; Humans; Male; Pl	1978
Corticosteroid therapy of alcoholic hepatitis. Gastroenterology, 1978, Volume: 75, Issue:2 Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Female; Hepatitis, Alcoholic; Humans; Male; Pl	1978
Corticosteroid therapy of alcoholic hepatitis. Gastroenterology, 1978, Volume: 75, Issue:2 Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Female; Hepatitis, Alcoholic; Humans; Male; Pl	1978
Corticosteroid therapy of alcoholic hepatitis. Gastroenterology, 1978, Volume: 75, Issue:2 Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Female; Hepatitis, Alcoholic; Humans; Male; Pl	1978
Corticosteroid therapy of alcoholic hepatitis. Gastroenterology, 1978, Volume: 75, Issue:2 Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Female; Hepatitis, Alcoholic; Humans; Male; Pl	1978
Corticosteroid therapy of alcoholic hepatitis. Gastroenterology, 1978, Volume: 75, Issue:2 Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Female; Hepatitis, Alcoholic; Humans; Male; Pl	1978
Corticosteroid therapy of alcoholic hepatitis. Gastroenterology, 1978, Volume: 75, Issue:2 Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Female; Hepatitis, Alcoholic; Humans; Male; Pl	1978
Corticosteroid therapy of alcoholic hepatitis. Gastroenterology, 1978, Volume: 75, Issue:2 Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Female; Hepatitis, Alcoholic; Humans; Male; Pl	1978
Steroid treatment of alcoholic hepatitis. The yeas and the nays. Gastroenterology, 1978, Volume: 74, Issue:2 Pt 1 Topics: Female; Hepatic Encephalopathy; Hepatitis, Alcoholic; Humans; Male; Prednisolone; Prognosis; Researc	1978
Hepatology elsewhere: twenty years after! Hepatology (Baltimore, Md.), 1992, Volume: 16, Issue:4 Topics: Double-Blind Method; Hepatitis, Alcoholic; Humans; Meta-Analysis as Topic; Prednisolone	1992
Steroids in alcohol hepatitis: hope or hype? The American journal of gastroenterology, 1992, Volume: 87, Issue:12 Topics: Hepatitis, Alcoholic; Humans; Prednisolone; Survival Rate	1992
A randomized trial of prednisolone in patients with severe alcoholic hepatitis. The New England journal of medicine, 1992, Feb-20, Volume: 326, Issue:8 Topics: Double-Blind Method; Female; Follow-Up Studies; Hepatic Encephalopathy; Hepatitis, Alcoholic; Humans	1992
Prednisolone in severe alcoholic hepatitis. The New England journal of medicine, 1992, Jul-23, Volume: 327, Issue:4 Topics: Female; Hepatitis, Alcoholic; Humans; Male; Prednisolone	1992
[Corticoid therapy in the treatment of acute alcoholic hepatitis. Results of a meta-analysis]. Gastroenterologie clinique et biologique, 1991, Volume: 15, Issue:3 Topics: Acute Disease; Hepatitis, Alcoholic; Humans; Meta-Analysis as Topic; Methylprednisolone; Prednisolon	1991
[Treatment of acute alcoholic hepatitis with prednisolone. 45 patients]. Presse medicale (Paris, France : 1983), 1987, May-02, Volume: 16, Issue:16 Topics: Acute Disease; Adult; Aged; Clinical Trials as Topic; Female; Hepatitis, Alcoholic; Humans; Male; Mi	1987

Article	Year
Letter to the editor: Combination treatment with IL-1 antagonist, pentoxifylline and zinc for severe alcoholic hepatitis: Are we there yet? Hepatology (Baltimore, Md.), 2022, Volume: 76, Issue:5 Topics: Hepatitis, Alcoholic; Humans; Interleukin-1; Pentoxifylline; Prednisolone; Zinc	2022
Letter to the editor: IL-1 receptor antagonist plus pentoxifylline and zinc for severe alcoholic hepatitis-More questions than answers! Hepatology (Baltimore, Md.), 2022, Volume: 76, Issue:5 Topics: Hepatitis, Alcoholic; Humans; Pentoxifylline; Prednisolone; Receptors, Interleukin-1; Zinc	2022
In severe alcohol-related hepatitis, acute kidney injury is prevalent, associated with mortality independent of liver disease severity, and can be predicted using IL-8 and micro-RNAs. Alimentary pharmacology & therapeutics, 2023, Volume: 58, Issue:11-12 Topics: Acute Kidney Injury; Biomarkers; Hepatitis, Alcoholic; Humans; Interleukin-8; MicroRNAs; Patient Acu	2023
In Severe Alcoholic Hepatitis, Serum Keratin-18 Fragments Are Diagnostic, Prognostic, and Theragnostic Biomarkers. The American journal of gastroenterology, 2020, Volume: 115, Issue:11 Topics: Adult; Biopsy; End Stage Liver Disease; Female; Glucocorticoids; Hepatitis, Alcoholic; Humans; Kerat	2020
Circulating levels of bacterial DNA and risk of infections in severe alcoholic hepatitis. Clinics and research in hepatology and gastroenterology, 2017, Volume: 41, Issue:4 Topics: DNA, Bacterial; Glucocorticoids; Hepatitis, Alcoholic; Humans; Prednisolone; Risk	2017
Corticosteroids, nutrition, pentoxifylline, or fecal microbiota transplantation for severe alcoholic hepatitis. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2018, Volume: 37, Issue:3 Topics: Administration, Oral; Adult; Aged; Fecal Microbiota Transplantation; Feces; Female; Gastrointestinal	2018
Baseline neutrophil-to-lymphocyte ratio predicts response to corticosteroids and is associated with infection and renal dysfunction in alcoholic hepatitis. Alimentary pharmacology & therapeutics, 2019, Volume: 50, Issue:4 Topics: Acute Kidney Injury; Adrenal Cortex Hormones; Biomarkers, Pharmacological; Female; Hepatitis, Alcoho	2019
Treatment of severe alcoholic hepatitis with corticosteroids and pentoxifylline. JAMA, 2013, Sep-11, Volume: 310, Issue:10 Topics: Female; Free Radical Scavengers; Glucocorticoids; Hepatitis, Alcoholic; Humans; Male; Pentoxifylline	2013
Index of suspicion. Case 1: fever, diarrhea, jaundice, and confusion in an 18-year-old male. Case 2: severe anemia in a 6-month-old girl. Case 3: red urine in a 4-month-old boy. Pediatrics in review, 2014, Volume: 35, Issue:3 Topics: Acyl-CoA Dehydrogenase, Long-Chain; Adolescent; Anemia; Anti-Inflammatory Agents; Confusion; Congeni	2014
Long-term outcome in patients with severe alcoholic hepatitis can be reliably determined using an in vitro measure of steroid sensitivity. Hepatology (Baltimore, Md.), 2015, Volume: 61, Issue:3 Topics: Female; Hepatitis, Alcoholic; Humans; Male; Middle Aged; Prednisolone; ROC Curve	2015
Prednisolone vs. pentoxifylline for severe alcoholic hepatitis. Journal of hepatology, 2014, Volume: 61, Issue:4 Topics: Anti-Inflammatory Agents; Hepatitis, Alcoholic; Humans; Patient Selection; Pentoxifylline; Phosphodi	2014
Prognosis of treated severe alcoholic hepatitis in patients with gastrointestinal bleeding. Journal of hepatology, 2015, Volume: 62, Issue:4 Topics: Adult; Anti-Inflammatory Agents; Biopsy; Female; France; Gastrointestinal Hemorrhage; Hepatitis, Alc	2015
Is petoxifylline still an option in severe alcoholic hepatitis? Hepatology (Baltimore, Md.), 2015, Volume: 61, Issue:4 Topics: Female; Hepatitis, Alcoholic; Humans; Male; Pentoxifylline; Prednisolone	2015
Corticosteroids can be used to treat alcoholic hepatitis after a recent upper gastrointestinal bleed. Journal of hepatology, 2015, Volume: 62, Issue:4 Topics: Female; Gastrointestinal Hemorrhage; Hepatitis, Alcoholic; Humans; Liver Cirrhosis; Male; Prednisolo	2015
[Pentoxifylline against prednisolone in severe acute alcoholic hepatitis: a Korean trial]. La Revue du praticien, 2014, Volume: 64, Issue:9 Topics: Acute Disease; Adult; Hepatitis, Alcoholic; Humans; Multicenter Studies as Topic; Pentoxifylline; Pr	2014
Reply: To PMID 25502967. Hepatology (Baltimore, Md.), 2015, Volume: 62, Issue:5 Topics: Female; Hepatitis, Alcoholic; Humans; Male; Pentoxifylline; Prednisolone	2015
Is pentoxifylline still an option in severe alcoholic hepatitis? Hepatology (Baltimore, Md.), 2015, Volume: 62, Issue:5 Topics: Female; Hepatitis, Alcoholic; Humans; Male; Pentoxifylline; Prednisolone	2015
Prednisolone or Pentoxifylline for Alcoholic Hepatitis. The New England journal of medicine, 2015, 07-16, Volume: 373, Issue:3 Topics: Female; Glucocorticoids; Hepatitis, Alcoholic; Humans; Male; Pentoxifylline; Prednisolone	2015
Prednisolone or Pentoxifylline for Alcoholic Hepatitis. The New England journal of medicine, 2015, 07-16, Volume: 373, Issue:3 Topics: Female; Glucocorticoids; Hepatitis, Alcoholic; Humans; Male; Pentoxifylline; Prednisolone	2015
Prednisolone or Pentoxifylline for Alcoholic Hepatitis. The New England journal of medicine, 2015, 07-16, Volume: 373, Issue:3 Topics: Female; Glucocorticoids; Hepatitis, Alcoholic; Humans; Male; Pentoxifylline; Prednisolone	2015
Defective monocyte oxidative burst predicts infection in alcoholic hepatitis and is associated with reduced expression of NADPH oxidase. Gut, 2017, Volume: 66, Issue:3 Topics: Adult; Anti-Inflammatory Agents; Bacterial Infections; Case-Control Studies; Cells, Cultured; Cocult	2017
Infections complicating severe alcoholic hepatitis: Enterococcus species represent the most frequently identified pathogen. Scandinavian journal of gastroenterology, 2016, Volume: 51, Issue:7 Topics: Adult; Aged; Enterococcus; Female; Gram-Negative Bacterial Infections; Hepatitis, Alcoholic; Humans;	2016
Prednisolone plus S-adenosil-L-methionine in severe alcoholic hepatitis. Hepatology international, 2016, Volume: 10, Issue:6 Topics: Drug Administration Schedule; Drug Therapy, Combination; Female; Glucocorticoids; Hepatitis, Alcohol	2016
Alcoholic hepatitis: should we combine old drugs for better results? Hepatology international, 2016, Volume: 10, Issue:6 Topics: Acetylcysteine; Antioxidants; Clinical Trials as Topic; Disease Management; Drug Therapy, Combinatio	2016
A Day-4 Lille Model Predicts Response to Corticosteroids and Mortality in Severe Alcoholic Hepatitis. The American journal of gastroenterology, 2017, Volume: 112, Issue:2 Topics: Adult; Age Factors; Bilirubin; Brazil; Case-Control Studies; Cohort Studies; Creatinine; Discriminan	2017
Alcoholic liver disease: Alcoholic hepatitis: a warning for prednisolone and infection risk? Nature reviews. Gastroenterology & hepatology, 2017, Volume: 14, Issue:2 Topics: Hepatitis, Alcoholic; Humans; Infections; Liver; Liver Diseases, Alcoholic; Prednisolone	2017
The place of liver transplantation in the treatment of severe alcoholic hepatitis. Journal of hepatology, 2010, Volume: 52, Issue:5 Topics: Bilirubin; Creatinine; Glasgow Coma Scale; Hepatitis, Alcoholic; Humans; Liver Transplantation; Pati	2010
In vitro steroid resistance correlates with outcome in severe alcoholic hepatitis. Hepatology (Baltimore, Md.), 2011, Volume: 53, Issue:4 Topics: Antibodies, Monoclonal; Basiliximab; Bilirubin; Drug Resistance; Hepatitis, Alcoholic; Humans; Inter	2011
Glucocorticoids plus N-acetylcysteine in alcoholic hepatitis. The New England journal of medicine, 2012, 02-02, Volume: 366, Issue:5 Topics: Acetylcysteine; Antioxidants; Female; Glucocorticoids; Hepatitis, Alcoholic; Humans; Male; Prednisol	2012
[A case of alcoholic hepatitis diagnosed by a liver biopsy and successfully treated by corticosteroid therapy]. Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2012, Volume: 109, Issue:4 Topics: Biopsy; Hepatitis, Alcoholic; Humans; Liver; Male; Methylprednisolone; Middle Aged; Prednisolone	2012
Severe alcoholic hepatitis successfully treated by leukocytapheresis: a case report. Alcoholism, clinical and experimental research, 2003, Volume: 27, Issue:8 Suppl Topics: Actuarial Analysis; Adult; Biopsy; C-Reactive Protein; Combined Modality Therapy; Granulocytes; Hepa	2003
Early change in bilirubin levels is an important prognostic factor in severe alcoholic hepatitis treated with prednisolone. Hepatology (Baltimore, Md.), 2003, Volume: 38, Issue:6 Topics: Adult; Aged; Bilirubin; Female; Hepatitis, Alcoholic; Humans; Male; Middle Aged; Multivariate Analys	2003
Infliximab and prednisolone: too much of a good thing? Hepatology (Baltimore, Md.), 2004, Volume: 39, Issue:6 Topics: Antibodies, Monoclonal; Clinical Trials as Topic; Hepatitis, Alcoholic; Humans; Infliximab; Predniso	2004
Infliximab and alcoholic hepatitis. Hepatology (Baltimore, Md.), 2004, Volume: 40, Issue:2 Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal; Dose-Response Relationship, Drug; Drug Therapy, Co	2004
Combining steroids with enteral nutrition: a better therapeutic strategy for severe alcoholic hepatitis? Results of a pilot study. European journal of gastroenterology & hepatology, 2004, Volume: 16, Issue:12 Topics: Adult; Alcohol Drinking; Combined Modality Therapy; Communicable Diseases; Drug Administration Sched	2004
Bilirubin response to corticosteroids in severe alcoholic hepatitis. European journal of gastroenterology & hepatology, 2005, Volume: 17, Issue:7 Topics: Administration, Oral; Anti-Infective Agents; Bilirubin; Glucocorticoids; Hepatitis, Alcoholic; Human	2005
Glucocorticoid-induced leucine zipper: A key protein in the sensitization of monocytes to lipopolysaccharide in alcoholic hepatitis. Hepatology (Baltimore, Md.), 2007, Volume: 46, Issue:6 Topics: Glucocorticoids; Hepatitis, Alcoholic; Humans; Leucine Zippers; Lipopolysaccharides; Liver; Monocyte	2007
Bronchiolitis obliterans organizing pneumonia associated with Pneumocystis jiroveci infection in orthotopic liver transplantation. Transplant infectious disease : an official journal of the Transplantation Society, 2008, Volume: 10, Issue:5 Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Biopsy; Cryptogenic Organizing Pneumonia; Diagnosis	2008
Clinical conferences at the John Hopkins Hospital: alcoholic hepatitis. The Johns Hopkins medical journal, 1982, Volume: 150, Issue:2 Topics: Hepatitis, Alcoholic; Humans; Liver; Male; Middle Aged; Prednisolone	1982
Alcohol modulation of immune function: clinical and experimental data. Veterans Affairs Cooperative Study Groups 119 and 275. Alcoholism, clinical and experimental research, 1995, Volume: 19, Issue:3 Topics: Animals; Combined Modality Therapy; Follow-Up Studies; Food, Fortified; Hepatitis, Alcoholic; Humans	1995
[Severe acute alcoholic hepatitis after corticoid withdrawal]. Annales de medecine interne, 1994, Volume: 145, Issue:6 Topics: Acute Disease; Female; Hepatitis, Alcoholic; Humans; Middle Aged; Prednisolone	1994
Plasma levels of soluble tumor necrosis factor receptors p55 and p75 in patients with alcoholic liver disease of increasing severity. Journal of hepatology, 1998, Volume: 28, Issue:5 Topics: Adult; Antigens, CD; Bilirubin; Hepatitis, Alcoholic; Humans; Liver Cirrhosis, Alcoholic; Liver Dise	1998
Rapid changes in alcoholic hepatitis histology under steroids: correlation with soluble intercellular adhesion molecule-1 in hepatic venous blood. Journal of hepatology, 2001, Volume: 35, Issue:5 Topics: Adult; Aged; Anti-Inflammatory Agents; Bilirubin; Biopsy; Female; Hemodynamics; Hepatic Veins; Hepat	2001
Alcoholic hepatitis: treatment with steroids. Gastroenterology, 1978, Volume: 75, Issue:1 Topics: Hepatitis, Alcoholic; Humans; Prednisolone	1978
In vitro effect of prednisolone on peripheral blood suppressor T cell activity in patients with alcoholic hepatitis. Clinical immunology and immunopathology, 1989, Volume: 53, Issue:2 Pt 1 Topics: Female; Hepatitis, Alcoholic; Humans; Immune Tolerance; Lymphocyte Cooperation; Male; Prednisolone;	1989
VA cooperative study on alcoholic hepatitis. II: Prognostic significance of protein-calorie malnutrition. The American journal of clinical nutrition, 1986, Volume: 43, Issue:2 Topics: Energy Intake; Energy Metabolism; Hepatitis, Alcoholic; Humans; Liver; Oxandrolone; Prednisolone; Pr	1986
Treatment of chronic active hepatitis and other liver diseases with corticosteroid agents. The Medical journal of Australia, 1987, Apr-06, Volume: 146, Issue:7 Topics: Adrenal Cortex Hormones; Autoimmune Diseases; Azathioprine; Hepatitis, Alcoholic; Hepatitis, Chronic	1987

prednisolone and Alcoholic Hepatitis

Research Excerpts

Research

Studies (91)

Authors

Clinical Trials (12)

Trial Overview

Reviews

Trials

Other Studies

Authors	Studies
Gupta, S	1
Nath, P	1
Anand, AC	1
Singh, SP	1
Mishra, AK	1
Jindal, A	1
Pande, A	3
Sharma, S	2
Khillan, V	2
Rastogi, A	3
Arora, V	3
Shasthry, SM	4
Vijayaraghavan, R	3
Jagdish, R	2
Kumar, M	2
Kumar, G	2
Mondot, S	2
Dore, J	2
Sarin, SK	4
Louvet, A	6
Labreuche, J	2
Dao, T	2
Thévenot, T	3
Oberti, F	2
Bureau, C	1
Paupard, T	2
Nguyen-Khac, E	2
Minello, A	1
Bernard-Chabert, B	2
Anty, R	2
Wartel, F	1
Carbonell, N	4
Pageaux, GP	2
Hilleret, MN	1
Moirand, R	2
Nahon, P	2
Potey, C	1
Duhamel, A	3
Mathurin, P	8
Yoon, EL	1
Kim, W	2
Tyson, LD	1
Atkinson, S	1
Hunter, RW	1
Allison, M	5
Austin, A	5
Dear, JW	1
Forrest, E	2
Liu, T	1
Lord, E	1
Masson, S	5
Nunes, J	1
Richardson, P	5
Ryder, SD	2
Wright, M	4
Thursz, M	3
Vergis, N	6
Chaiteerakij, R	1
Sanpawat, A	1
Avihingsanon, A	1
Treeprasertsuk, S	1
Atkinson, SR	5
Grove, JI	1
Liebig, S	1
Astbury, S	1
Goldin, R	1
Quaglia, A	1
Bantel, H	1
Guha, IN	1
Thursz, MR	7
Newcombe, P	1
Strnad, P	1
Aithal, GP	1
Glavind, E	1
Aagaard, NK	1
Gronbaek, H	1
Orntoft, NW	1
Vilstrup, H	1
Thomsen, KL	1
Bihari, C	1
Sharma, MK	2
Sahlman, P	1
Nissinen, M	1
Simonen, P	1
Färkkilä, M	1
Kim, DJ	3
Sidhu, SS	2
O'Grady, JG	1
Akriviadis, E	1
Sinakos, E	1
Carithers, RL	1
Ramond, MJ	4
Maddrey, WC	2
Morgan, TR	4
Philips, CA	1
Phadke, N	1
Ganesan, K	1
Ranade, S	1
Augustine, P	1
Im, GY	1
Cho, Y	1
Park, YS	1
Kim, HY	1
Lee, HJ	2
Shasthry, V	1
Forrest, EH	5
Storey, N	1
Sinha, R	1
Ryder, S	4
Fraser, A	1
McCune, A	5
Dhanda, A	1
Katarey, D	1
Potts, J	1
Verma, S	1
Parker, R	2
Hayes, PC	1
Halegoua-De Marzio, DL	1
Fenkel, JM	1
Boursier, J	1
Diaz, E	2
Thabut, D	2
Lebrec, D	1
Moreno, C	1
Talbodec, N	1
Naveau, S	5
Silvain, C	1
Sobesky, R	1
Canva-Delcambre, V	1
Dharancy, S	3
Salleron, J	1
Ku, E	1
Thomas, M	1
Ho, CH	1
Whipple, NS	1
Abdul-Rahman, O	1
Megason, GC	1
Herrington, BL	1
Carmody, JB	1
Charlton, JR	1
Casanova, J	1
Bataller, R	3
Dhanda, AD	1
di Mambro, AJ	2
Hunt, VL	1
McCune, CA	1
Dayan, CM	2
Dick, AD	1
Lee, RW	1
Collins, PL	1
Park, SH	1
Kim, YS	1
Yim, HJ	1
Tak, WY	1
Sohn, JH	1
Yoon, KT	1
Kim, IH	1
Kim, HS	1
Um, SH	1
Baik, SK	1
Lee, JS	1
Suk, KT	1
Kim, SG	1
Suh, SJ	1
Park, SY	1
Kim, TY	1
Jang, JY	1
Rudler, M	2
Mouri, S	1
Charlotte, F	1
Lebray, P	1
Capocci, R	1
Benosman, H	1
Poynard, T	3
Caballeria, J	3
Chanson, P	1
Pariente, A	1
Townsend, SA	1
Rowe, IA	1
Elsharkawy, AM	1
Bowers, M	2
Day, CP	1
Downs, N	2
Gleeson, D	3
MacGilchrist, A	1
Grant, A	1
Hood, S	1
Mellor, J	2
O'Grady, J	3
Patch, D	3
Ratcliffe, I	2
Roderick, P	2
Stanton, L	2
Verbeke, L	1
Laleman, W	1
Nevens, F	1
DiNubile, MJ	1
Day, C	1
Vale, L	1
Kirkman, S	1
Homer, T	1
Ternent, L	1
Khamri, W	1
Beale, K	1
Sadiq, F	1
Aletrari, MO	1
Moore, C	1
Bernsmeier, C	1
Possamai, LA	1
Petts, G	1
Ryan, JM	1
Abeles, RD	1
James, S	1
Foxton, M	1
Hogan, B	1
Foster, GR	1
O'Brien, AJ	1
Ma, Y	1
Shawcross, DL	1
Wendon, JA	1
Antoniades, CG	1
Beisel, C	1
Blessin, U	1
Schulze Zur Wiesch, J	1
Wehmeyer, MH	1
Lohse, AW	1
Benten, D	1
Kluwe, J	1
Tkachenko, P	1
Maevskaya, M	1
Pavlov, A	1
Komkova, I	1
Pavlov, C	1
Ivashkin, V	1
Phillips, PK	1
Lucey, MR	2
Cabezas, J	1
Garcia-Saenz-de-Sicilia, M	1
Duvoor, C	1
Altamirano, J	1
Chavez-Araujo, R	1
Prado, V	1
de Lourdes Candolo-Martinelli, A	1
Holanda-Almeida, P	1
Becerra-Martins-de-Oliveira, B	1
Fernandez-de-Almeida, S	1
Duarte-Rojo, A	1
Knapp, S	1
Maurice, J	1
Ray, K	1
Goyal, O	1
Kishore, H	1
Sidhu, S	1
De, BK	1
Gangopadhyay, S	1
Dutta, D	1
Baksi, SD	1
Pani, A	1
Ghosh, P	1
Cohen, SM	1
Ahn, J	1
Dureja, P	1
Amini, M	1
Runyon, BA	1
Gordon, F	1
Collins, P	1
Piquet, MA	2
Benferhat, S	1
Goria, O	1
Chatelain, D	1
Tramier, B	1
Dewaele, F	1
Ghrib, S	1
Tossou, H	1
Bental, A	1
Dupas, JL	1
Lake-Bakaar, G	1
Taniguchi, H	1
Shibagaki, K	1
Seshimo, K	1
Kobayashi, K	1
Tsuji, Y	1
Kumashiro, R	1
Ishii, K	1
Arinaga, T	1
Sakamoto, Y	1
Tanabe, R	1
Ogata, K	1
Koga, Y	1
Ide, T	1
Ono, N	1
Tanaka, E	1
Abe, H	1
Sata, M	1
Abdelnour, M	1
Fartoux, L	1
Serfaty, L	1
Valla, D	1
Poupon, R	1
Chaput, JC	4
Chollet-Martin, S	1
Jouet, P	1
Davion, T	1
Broët, P	1
Emilie, D	3
McClain, CJ	1
Hill, DB	1
Barve, SS	1
Mookerjee, RP	1
Tilg, H	1
Williams, R	2
Jalan, R	1
Alvarez, MA	1
Cabré, E	1
Lorenzo-Zúñiga, V	1
Montoliu, S	1
Planas, R	1
Gassull, MA	1
Morris, JM	1
Phillips, M	1
Curtis, H	1
Portmann, B	1
Donaldson, N	1
Bomford, A	1
Hamdi, H	1
Bigorgne, A	1
Balian, A	2
Bouchet-Delbos, L	1
Cassard-Doulcier, AM	1
Maillot, MC	1
Durand-Gasselin, I	1
Prévot, S	1
Delaveaucoupet, J	1
Perlemuter, G	1
Coevoet, H	1
Texier, F	1
Deltenre, P	1
Canva, V	1
Plane, C	1
Almaslmani, M	1
Derbala, MF	1
Albozom, I	1
Khattab, M	1
Chacko, K	1
Alani, A	1
Galambos, JT	1
Riepe, SP	1
Mendenhall, CL	3
Anderson, S	1
Garcia-Pont, P	2
Goldberg, S	1
Kiernan, T	2
Seeff, LB	2
Sorrell, M	1
Tamburro, C	2
Weesner, R	1
Zetterman, R	2
Abonyi, M	1
Kisfaludy, S	1
Szalay, F	1
Depew, W	1
Boyer, T	1
Omata, M	1
Redeker, A	1
Reynolds, T	1
Roselle, GA	2
Chedid, A	1
Moritz, TE	1
Gartside, P	2
Mendenhall, C	1
Moritz, T	1
Turner, L	1
Lesur, G	1
Grasland, A	1
Nobillot, R	1
Bergemer, AM	1
Dorra, M	1
Le Parc, JM	1
Duchatelle, V	1
Degott, C	1
Bedossa, P	1
Erlinger, S	1
Benhamou, JP	2
Rueff, B	2
Grangeot-Keros, L	1
Borotto, E	1
Portier, A	1
Giraud, V	1
Capron, F	1
Galanaud, P	1
Spahr, L	1
Rubbia-Brandt, L	1
Pugin, J	1
Giostra, E	1
Frossard, JL	1
Borisch, B	1
Hadengue, A	1
Lesesne, HR	1
Bozymski, EM	1
Fallon, HJ	1
Boitnott, JK	1
Bedine, MS	1
Weber, FL	1
Mezey, E	1
White, RI	1
Jacobucci, L	1
Conn, HO	1
Blendis, LM	1
Simon, D	1
Théodore, C	1
Daures, JP	1
Peray, P	1
Bories, P	2
Blanc, P	1
Yousfi, A	2
Michel, H	2
Gremy, F	1
Bird, GL	1
Ezzell, JH	1
Werkman, RF	1
Dean, P	1
Ikeda, T	1
Daiguji, Y	1
Hasumura, Y	1
Takeuchi, J	1
Guedj, JY	1
Mirouze, D	1
Tosch, T	1
Weesner, RE	1
Goldberg, SJ	1
Sorell, M	1
Mackay, IR	1