Page last updated: 2024-11-06

prednisolone and Aging

prednisolone has been researched along with Aging in 73 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"We investigated the possible ameliorating and preventive effect of swimming on prednisolone-induced osteoporosis in elderly rats."7.68Effect of swimming on prednisolone-induced osteoporosis in elderly rats. ( Azevedo, J; Azoury, R; Brooks, GA; Greenfield, C; Leichter, I; Oman, S; Statter, M; Swissa-Sivan, A; Viguie, C; Zinker, BA, 1992)
"Circadian, continued treatment with melatonin during the dark cycle produces changes in the blood level of thyroid hormones in aging mice."7.68The involvement of pineal gland and melatonin in immunity and aging. I. Thymus-mediated, immunoreconstituting and antiviral activity of thyrotropin-releasing hormone. ( Pierpaoli, W; Yi, C, 1990)
"The pharmacokinetics of a 40-mg intravenous dose of prednisolone were determined in 10 steroid-dependent asthmatic children with highly variable prednisone requirements (5 mg every other day to 40 mg a day)."7.66Prednisolone disposition in steroid-dependent asthmatic children. ( Ellis, EF; Jusko, WJ; Middleton, E; Nickelsen, JA; Rose, JQ, 1981)
" Our findings suggested that the initial dosage of theophylline should be adjusted according to the gender of pediatric patients and particularly in the case of infants."5.35Effect of gender on theophylline clearance in the asthmatic acute phase in Japanese pediatric patients. ( Igarashi, T; Iwakawa, S, 2009)
"Patients with non-viral infections seemed to have more depressed lymphocyte responses than non-infected patients."5.27Immunological recovery after bone marrow transplantation: role of age, graft-versus-host disease, prednisolone treatment and infections. ( Nilsson, B; Paulin, T; Ringdén, O, 1987)
"The aging process itself may have a small effect on the pharmacokinetics of tacrolimus, MPA, or prednisolone."3.75No impact of age on dose-adjusted pharmacokinetics of tacrolimus, mycophenolic acid and prednisolone 1 month after renal transplantation. ( Habuchi, T; Inoue, T; Kagaya, H; Miura, M; Saito, M; Satoh, S; Suzuki, T; Tsuchiya, N, 2009)
"To identify the effects of a tower-climbing exercise on bone marrow heme biosynthesis and hematological status in rats given glucocorticoid-injections as a model of aging, 29 male Sprague-Dawley rats, 10 weeks of age, were assigned to three groups: a saline control (C, n = 9), a glucocorticoid-sedentary (GS, n = 10) group, and a glucocorticoid-exercise (GE, n = 10) group."3.71Effects of voluntary resistance exercise on heme biosynthesis in rats given glucocorticoid-injections. ( Choue, RW; Kang, HS; Matsuo, T; Suzuki, M, 2002)
"We investigated the possible ameliorating and preventive effect of swimming on prednisolone-induced osteoporosis in elderly rats."3.68Effect of swimming on prednisolone-induced osteoporosis in elderly rats. ( Azevedo, J; Azoury, R; Brooks, GA; Greenfield, C; Leichter, I; Oman, S; Statter, M; Swissa-Sivan, A; Viguie, C; Zinker, BA, 1992)
" In order to clarify the physiologic changes of glucocorticoid receptor (GR) we measured the GR content of BAL cells obtained from rabbits with various conditions of the host (aging, immunological activation, malnutrition and pretreatment with prednisolone)."3.68[Influence of various factors on glucocorticoid receptors of bronchoalveolar lavage (BAL) cells from rabbits]. ( Chida, K; Sato, A; Shirai, M, 1991)
"Circadian, continued treatment with melatonin during the dark cycle produces changes in the blood level of thyroid hormones in aging mice."3.68The involvement of pineal gland and melatonin in immunity and aging. I. Thymus-mediated, immunoreconstituting and antiviral activity of thyrotropin-releasing hormone. ( Pierpaoli, W; Yi, C, 1990)
"The pharmacokinetics of a 40-mg intravenous dose of prednisolone were determined in 10 steroid-dependent asthmatic children with highly variable prednisone requirements (5 mg every other day to 40 mg a day)."3.66Prednisolone disposition in steroid-dependent asthmatic children. ( Ellis, EF; Jusko, WJ; Middleton, E; Nickelsen, JA; Rose, JQ, 1981)
"Idiopathic membranous nephropathy (IMN) is increasingly seen in older patients."2.79Patient age and the prognosis of idiopathic membranous nephropathy. ( Akiyama, S; Ando, M; Ito, Y; Kato, S; Katsuno, T; Kosugi, T; Maruyama, S; Matsuo, S; Mizuno, M; Sato, W; Tsuboi, N; Yamaguchi, M; Yamamoto, R; Yasuda, Y, 2014)
"Idarubicin was preferred to other anthracyclines because of its shorter time to response."2.68Age-adapted moderate-dose induction and flexible outpatient postremission therapy for elderly patients with acute lymphoblastic leukemia. ( Barbui, T; Bassan, R; Buelli, M; D'Emilio, A; Di Bona, E; Lerede, T; Pogliani, E; Rambaldi, A; Rodeghiero, F; Rossi, G; Viero, P, 1996)
" Our findings suggested that the initial dosage of theophylline should be adjusted according to the gender of pediatric patients and particularly in the case of infants."1.35Effect of gender on theophylline clearance in the asthmatic acute phase in Japanese pediatric patients. ( Igarashi, T; Iwakawa, S, 2009)
"In Caucasian type 1 autoimmune hepatitis patients with a main susceptibility of human leukocyte antigen DR3 and DR4, elderly patients have a higher frequency of concurrent autoimmune disease and cirrhosis at presentation."1.34Clinical features of Japanese elderly patients with type 1 autoimmune hepatitis. ( Iwasaki, Y; Kobashi, H; Miyake, Y; Sakaguchi, K; Shiratori, Y; Takaki, A, 2007)
"To investigate the impact of severe acute respiratory syndrome (SARS) on the physical fitness and health-related quality of life (HRQOL) among SARS survivors."1.33The impact of severe acute respiratory syndrome on the physical profile and quality of life. ( Hui, DS; Jones, AY; Lau, HM; Lee, EW; Ng, GY; Wong, CN, 2005)
" The correlation of proximal muscle strength, but not HG strength, with steroid dosage further supports a cause-effect relationship."1.32Corticosteroids and skeletal muscle function in cystic fibrosis. ( Barry, SC; Gallagher, CG, 2003)
"Treatment with prednisolone or dexamethasone is followed by an increase in renal excretion of p-aminohippurate (PAH) and in accumulation of PAH in renal cortical slices, particularly in 5- and 10-day-old rats with immature kidney function."1.28Stimulation of renal tubular transport of p-aminohippurate in rats of different ages by treatment with adrenocortical steroids. ( Bräunlich, H; Rassbach, H; Vogelsang, S, 1992)
"In the group with malignant tumors, with liver cirrhosis and with heavy drinkers, the loss of bone volume appears to be considerable in younger individuals but no difference from the controls could be found in older individuals."1.27[A quantitative morphologic study of cancellous bone--comparative study between physiological and pathological bone loss in autopsy cases]. ( Kameda, N, 1984)
"Patients with non-viral infections seemed to have more depressed lymphocyte responses than non-infected patients."1.27Immunological recovery after bone marrow transplantation: role of age, graft-versus-host disease, prednisolone treatment and infections. ( Nilsson, B; Paulin, T; Ringdén, O, 1987)

Research

Studies (73)

TimeframeStudies, this research(%)All Research%
pre-199038 (52.05)18.7374
1990's17 (23.29)18.2507
2000's12 (16.44)29.6817
2010's6 (8.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Merchant, HA1
Rabbie, SC1
Varum, FJ1
Afonso-Pereira, F1
Basit, AW1
Yamaguchi, M1
Ando, M1
Yamamoto, R1
Akiyama, S1
Kato, S1
Katsuno, T1
Kosugi, T1
Sato, W1
Tsuboi, N1
Yasuda, Y1
Mizuno, M1
Ito, Y1
Matsuo, S1
Maruyama, S1
Matic, I1
Matthews, BG1
Wang, X1
Dyment, NA1
Worthley, DL1
Rowe, DW1
Grcevic, D1
Kalajzic, I1
Igarashi, T1
Iwakawa, S1
Miura, M1
Satoh, S1
Kagaya, H1
Saito, M1
Inoue, T1
Tsuchiya, N1
Suzuki, T1
Habuchi, T1
Gutkowski, K1
Hartleb, M1
Tsukamoto, N1
Handa, H1
Yokohama, A1
Mitsui, T1
Saitoh, T1
Koiso, H1
Uchiumi, H1
Hoshino, T1
Karasawa, M1
Murakami, H1
Kojima, M1
Nojima, Y1
Maeda, S1
Fujino, Y1
Tamamoto, C1
Suzuki, S1
Fujita, A1
Takahashi, M1
Ohno, K1
Uchida, K1
Tsujimoto, H1
Kovina, MV1
Khavinson, VKh1
Strekalov, DL1
Solov'eva, DV1
Vorobtsova, IE1
Terekhov, SM1
Pleskach, NM1
Prokof'eva, VV1
Spivak, IM1
Timonina, GA1
Mikhel'son, VM1
Coiffier, B1
Iwai, H1
Lee, S1
Inaba, M1
Sugiura, K1
Baba, S1
Tomoda, K1
Yamashita, T1
Ikehara, S1
Kang, HS1
Matsuo, T1
Choue, RW1
Suzuki, M1
Barry, SC1
Gallagher, CG1
SCHMID, J1
MUSSA, GC1
PAVESIO, D1
HADNAGY, C1
HORVATH, E1
ELEKES, I1
PUIA, A1
NICOARA, E1
SASANO, N1
KITAGAWA, I1
MEDLEY, DR1
SCHMID, E1
WITTE, S1
PFANNMUELLER, B1
SCHRICKER, KT1
Batra, KV1
Schrek, R1
Lau, HM1
Lee, EW1
Wong, CN1
Ng, GY1
Jones, AY1
Hui, DS1
Kahaly, GJ1
Pitz, S1
Hommel, G1
Dittmar, M1
Jerjes, WK1
Taylor, NF1
Wood, PJ1
Cleare, AJ1
Miyake, Y1
Iwasaki, Y1
Takaki, A1
Kobashi, H1
Sakaguchi, K1
Shiratori, Y1
Lamers, WH2
Mooren, PG2
Skala, JP1
Hahn, P1
Knight, BL1
Robin, JC2
Ambrus, JL3
Kameda, N1
Vogel, HG5
Rose, JQ1
Nickelsen, JA1
Ellis, EF1
Middleton, E1
Jusko, WJ1
Hobden, JA1
Hill, JM1
Engel, LS1
O'Callaghan, RJ1
Ortoft, G1
Oxlund, H1
Bassan, R1
Di Bona, E1
Lerede, T1
Pogliani, E1
Rossi, G1
D'Emilio, A1
Buelli, M1
Rambaldi, A1
Viero, P1
Rodeghiero, F1
Barbui, T1
Tanaka, Y1
Nakamura, T1
Nishida, S1
Suzuki, K1
Takeda, S1
Sato, K1
Nishii, Y1
Syakalima, M1
Takiguchi, M1
Yasuda, J1
Hashimoto, A1
Diestelhorst, M1
Kwon, KA1
Süverkrup, R1
Inoue, Y1
Kanzaki, J1
Ogawa, K1
Hashiguchi, K1
Masuda, M1
Yan, H1
Harding, JJ1
Manelli, F1
Bossoni, S1
Carpinteri, R1
Bugari, G1
Panteghini, M1
Romanelli, G1
Giustina, A1
Cooper, MS1
Rabbitt, EH1
Goddard, PE1
Bartlett, WA1
Hewison, M1
Stewart, PM1
Crescini, B1
Schröder, S1
Christiansen, U1
Schütte, B1
Lindner, J1
Hilgner, W1
Kelly, RS1
Mannley, N1
Thomas, CC1
Howells, DW1
Hyland, K1
Smith, I1
Strobel, S1
Bräunlich, H1
Rassbach, H1
Vogelsang, S1
Nisar, M1
Earis, JE1
Pearson, MG1
Calverley, PM1
Modrowski, D1
del Pozo, E1
Miravet, L1
Swissa-Sivan, A1
Statter, M1
Brooks, GA1
Azevedo, J1
Viguie, C1
Azoury, R1
Greenfield, C1
Oman, S1
Leichter, I1
Zinker, BA1
Shirai, M1
Sato, A1
Chida, K1
Pierpaoli, W1
Yi, C1
Kamiya, M1
Sato, H1
Appelboom, T1
Mandelbaum, I1
Vertongen, F1
Rees, L1
Greene, SA1
Adlard, P1
Jones, J1
Haycock, GB1
Rigden, SP1
Preece, M1
Chantler, C1
Leunissen, KM1
Bosman, FT1
Kootstra, G1
van Hooff, JP1
Hayes, JM1
Novick, AC1
Steinmuller, DR1
Streem, SB1
Hodge, EE1
Bretan, PN1
Cunningham, R1
Graneto, D1
Frey, FJ2
Paulin, T1
Ringdén, O1
Nilsson, B1
Stuck, AE1
Frey, BM1
Yang, WC1
Schultz, RD1
Trivedi, P1
Cheeseman, P1
Portmann, B1
Hegarty, J1
Mowat, AP1
Bellamy, D2
Houck, JC1
De Hesse, C1
Jacob, R1
Gallagher, JC1
Aaron, J1
Horsman, A1
Wilkinson, R1
Nordin, BE1
Dil'man, VM1
Bölcskei, P1
Kellner, K1
Wüst, I1
Bondar', MV1
Sadovskaia, AG1
Ferdman, TD1
Harris, JE1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Development; Feasibility/Safety and Validation of the Alfred Step Test Exercise Protocol (A-STEP) Developed for Adults With Cystic Fibrosis:[NCT02717650]30 participants (Anticipated)Interventional2016-08-25Recruiting
"Geriatric Assessment Adapted Therapy for Ph- ALL Elderly Patients. GIMEMA Protocol LAL1104. EudraCT Code 2005-002156-17"[NCT00475280]Phase 2102 participants (Actual)Interventional2007-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for prednisolone and Aging

ArticleYear
Treatment paradigms in aggressive non-Hodgkin's lymphoma in elderly patients.
    Clinical lymphoma, 2002, Volume: 3 Suppl 1

    Topics: Age Factors; Aged; Aged, 80 and over; Aging; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-

2002
Role of glucocorticosteroid hormones on the levels of rat liver carbamoylphosphate synthase (ammonia) and arginase activity during ontogenesis.
    Biology of the neonate, 1980, Volume: 37, Issue:3-4

    Topics: Aging; Animals; Animals, Newborn; Arginase; Carbamoyl-Phosphate Synthase (Ammonia); Corticosterone;

1980
Kinetics and dynamics of prednisolone.
    Endocrine reviews, 1987, Volume: 8, Issue:4

    Topics: Aging; Animals; Humans; Intestinal Diseases; Kidney Diseases; Liver Diseases; Obesity; Prednisolone;

1987
Hormonal effects in relation to ageing in mammals.
    Symposia of the Society for Experimental Biology, 1967, Volume: 21

    Topics: Aging; Animals; Collagen; Endocrine Glands; Estradiol; Gonads; Hormones; Mice; Prednisolone; Rats; T

1967

Trials

3 trials available for prednisolone and Aging

ArticleYear
Patient age and the prognosis of idiopathic membranous nephropathy.
    PloS one, 2014, Volume: 9, Issue:10

    Topics: Age Factors; Aged; Aging; Anti-Inflammatory Agents; Cyclosporine; Follow-Up Studies; Glomerulonephri

2014
Randomized, single blind trial of intravenous versus oral steroid monotherapy in Graves' orbitopathy.
    The Journal of clinical endocrinology and metabolism, 2005, Volume: 90, Issue:9

    Topics: Administration, Oral; Adult; Aged; Aging; Dose-Response Relationship, Drug; Follow-Up Studies; Gluco

2005
Age-adapted moderate-dose induction and flexible outpatient postremission therapy for elderly patients with acute lymphoblastic leukemia.
    Leukemia & lymphoma, 1996, Volume: 22, Issue:3-4

    Topics: Aged; Aging; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Dose-Response Relationshi

1996

Other Studies

66 other studies available for prednisolone and Aging

ArticleYear
Influence of ageing on the gastrointestinal environment of the rat and its implications for drug delivery.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2014, Oct-01, Volume: 62

    Topics: Aging; Animals; Gastric Juice; Gastrointestinal Tract; Hydrogen-Ion Concentration; Intestinal Secret

2014
Quiescent Bone Lining Cells Are a Major Source of Osteoblasts During Adulthood.
    Stem cells (Dayton, Ohio), 2016, Volume: 34, Issue:12

    Topics: Actins; Aging; Animals; Biomarkers; Bone and Bones; Bone Marrow Cells; Cell Differentiation; Cell Li

2016
Effect of gender on theophylline clearance in the asthmatic acute phase in Japanese pediatric patients.
    Biological & pharmaceutical bulletin, 2009, Volume: 32, Issue:2

    Topics: Acute Disease; Aging; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Child; Child, Prescho

2009
No impact of age on dose-adjusted pharmacokinetics of tacrolimus, mycophenolic acid and prednisolone 1 month after renal transplantation.
    European journal of clinical pharmacology, 2009, Volume: 65, Issue:10

    Topics: Adult; Age Factors; Aged; Aging; Analysis of Variance; Area Under Curve; Body Weight; Cytochrome P-4

2009
Age and immunoglobulin G4-associated autoimmune hepatitis.
    Liver international : official journal of the International Association for the Study of the Liver, 2010, Volume: 30, Issue:2

    Topics: Aging; Glucocorticoids; Hepatitis, Autoimmune; Humans; Hypergammaglobulinemia; Immunoglobulin G; Liv

2010
Long-term follow-up of EBV-positive lymphoproliferative disorders in a patient with systemic lupus erythematosus.
    Medical molecular morphology, 2011, Volume: 44, Issue:4

    Topics: Adult; Aging; Epstein-Barr Virus Infections; Female; Glucocorticoids; Herpesvirus 4, Human; Humans;

2011
Lymphangiomatosis of the systemic skin in an old dog.
    The Journal of veterinary medical science, 2013, Volume: 75, Issue:2

    Topics: Aging; Animals; Anti-Inflammatory Agents; Dog Diseases; Dogs; Lymphangioma; Male; Prednisolone; Skin

2013
[Cytological and molecular changes in the atypical case of accelerated human aging].
    Tsitologiia, 2002, Volume: 44, Issue:10

    Topics: Adult; Aging; Anti-Inflammatory Agents; Cell Division; Cutis Laxa; Diagnosis, Differential; Fibrobla

2002
Correlation between accelerated presbycusis and decreased immune functions.
    Experimental gerontology, 2003, Volume: 38, Issue:3

    Topics: Aging; Animals; Evoked Potentials, Auditory, Brain Stem; Glucocorticoids; Mice; Mice, Inbred Strains

2003
Effects of voluntary resistance exercise on heme biosynthesis in rats given glucocorticoid-injections.
    Bioscience, biotechnology, and biochemistry, 2002, Volume: 66, Issue:12

    Topics: Aging; Animals; Body Weight; Bone Marrow; Erythrocytes; Glucocorticoids; Heme; Liver; Male; Muscle,

2002
Corticosteroids and skeletal muscle function in cystic fibrosis.
    Journal of applied physiology (Bethesda, Md. : 1985), 2003, Volume: 95, Issue:4

    Topics: Administration, Oral; Adrenal Cortex Hormones; Adult; Aging; Body Mass Index; Cystic Fibrosis; Extre

2003
[CALCIUM THERAPY OF OSTEOPOROSIS. DETERMINATION OF BONE DENSITY AS A CRITERION].
    Schweizerische medizinische Wochenschrift, 1963, Dec-21, Volume: 93

    Topics: Aging; Anabolic Agents; Arthritis; Arthritis, Rheumatoid; Bone and Bones; Bone Density; Calcium; Ger

1963
[STUDY ON THE BEHAVIOR OF POTASSIUM METABOLISM AFTER PREDNISOLONE TREATMENT IN VARIOUS AGES. (EXPERIMENTAL RESEARCH)].
    Minerva pediatrica, 1964, Jan-14, Volume: 16

    Topics: Aging; Animals; Body Fluids; Guinea Pigs; Minerals; Potassium; Potassium Isotopes; Prednisolone; Res

1964
EFFECT OF VITAMIN B12 AND CORTISONE ON THE GLUCOSE TOLERANCE OF AGED PERSONS.
    Gerontologia, 1964, Volume: 69

    Topics: Aging; Biomedical Research; Blood Glucose; Carbohydrate Metabolism; Cortisone; Diabetes Mellitus; Ge

1964
CORTICOSTEROID-INDUCED ATROPHY OF THE HUMAN ADRENALS COMPARABLE TO PANHYPOPITUITARISM; A HISTOPATHOLOGICAL STUDY.
    The Tohoku journal of experimental medicine, 1964, Aug-25, Volume: 83

    Topics: Adrenal Cortex Hormones; Adrenal Gland Diseases; Aging; Anemia; Anemia, Aplastic; Atrophy; Betametha

1964
THE RELATIONSHIP BETWEEN DIABETES AND OBESITY: A STUDY OF SUSCEPTIBILITY TO DIABETES IN OBESE PEOPLE.
    The Quarterly journal of medicine, 1965, Volume: 34

    Topics: Aging; Diabetes Mellitus; Genetics, Medical; Glucose Tolerance Test; Obesity; Pharmacology; Predniso

1965
[On the influence of prednisolone, nucleosides and amine oxidase inhibitors on serotonin binding by aging blood platelets].
    Thrombosis et diathesis haemorrhagica, 1962, May-15, Volume: 7

    Topics: Aging; Blood Platelets; Humans; Monoamine Oxidase Inhibitors; Nucleosides; Nucleotides; Oxidoreducta

1962
Effect of age and species on sensitivity of lymphocytes to prednisolone and phytohemagglutinin.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1967, Volume: 125, Issue:3

    Topics: Aging; Animals; Appendix; Humans; Lymphocytes; Mice; Phytohemagglutinins; Prednisolone; Rabbits; Rat

1967
The impact of severe acute respiratory syndrome on the physical profile and quality of life.
    Archives of physical medicine and rehabilitation, 2005, Volume: 86, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Case-Control Studies; Cohort Studies; Exercise Te

2005
Enhanced feedback sensitivity to prednisolone in chronic fatigue syndrome.
    Psychoneuroendocrinology, 2007, Volume: 32, Issue:2

    Topics: Adult; Aging; Body Mass Index; Fatigue Syndrome, Chronic; Feedback, Physiological; Female; Humans; H

2007
Clinical features of Japanese elderly patients with type 1 autoimmune hepatitis.
    Internal medicine (Tokyo, Japan), 2007, Volume: 46, Issue:24

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aging; Biopsy; Disease Progression; Female; Hepati

2007
Effect of insulin and prednisolone on cyclic nucleotides and phosphoenolpyruvate carboxykinase activity in brown fat and liver of developing rats.
    Biochimica et biophysica acta, 1980, Sep-01, Volume: 631, Issue:3

    Topics: Adipose Tissue, Brown; Aging; Animals; Cyclic AMP; Cyclic GMP; Enzyme Induction; Enzyme Repression;

1980
Studies on osteoporoses. VIII. Effect of estrogen on steroid induced osteoporosis.
    Journal of medicine, 1982, Volume: 13, Issue:5-6

    Topics: Adrenal Cortex Hormones; Aging; Animals; Calcium; Estrogens; Estrogens, Conjugated (USP); Female; Mi

1982
[A quantitative morphologic study of cancellous bone--comparative study between physiological and pathological bone loss in autopsy cases].
    Nihon Seikeigeka Gakkai zasshi, 1984, Volume: 58, Issue:7

    Topics: Adolescent; Adult; Aged; Aging; Alcoholism; Bone Resorption; Child; Diabetes Complications; Female;

1984
Influence of desmotropic drugs on viscoelastic properties of rat tail tendons. Hysteresis experiments.
    Arzneimittel-Forschung, 1984, Volume: 34, Issue:2

    Topics: Aging; Aminoacetonitrile; Animals; Body Weight; Connective Tissue; Elasticity; In Vitro Techniques;

1984
Role of sex steroid hormones in the normal and glucocorticosteroid hormone-induced evolution of carbamoylphosphate synthase (ammonia) and arginase activity in rat liver ontogenesis.
    Biology of the neonate, 1981, Volume: 40, Issue:1-2

    Topics: Aging; Animals; Arginase; Carbamoyl-Phosphate Synthase (Ammonia); Estradiol; Female; Lactation; Liga

1981
Prednisolone disposition in steroid-dependent asthmatic children.
    The Journal of allergy and clinical immunology, 1981, Volume: 67, Issue:3

    Topics: Aging; Asthma; Child; Dose-Response Relationship, Drug; Eosinophils; Female; Humans; Leukopenia; Mal

1981
Age and therapeutic outcome of experimental Pseudomonas aeruginosa keratitis treated with ciprofloxacin, prednisolone, and flurbiprofen.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:9

    Topics: Aging; Animals; Aqueous Humor; Biological Assay; Ciprofloxacin; Cornea; Drug Therapy, Combination; F

1993
Qualitative alterations of cortical bone in female rats after long-term administration of growth hormone and glucocorticoid.
    Bone, 1996, Volume: 18, Issue:6

    Topics: Administration, Oral; Aging; Animals; Bone Density; Bone Development; Bone Diseases, Metabolic; Bone

1996
Effects of a synthetic vitamin D analog, ED-71, on bone dynamics and strength in cancellous and cortical bone in prednisolone-treated rats.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1996, Volume: 11, Issue:3

    Topics: Absorptiometry, Photon; Aging; Amino Acids; Analysis of Variance; Animals; Biomechanical Phenomena;

1996
The age dependent levels of serum ALP isoenzymes and the diagnostic significance of corticosteroid-induced ALP during long-term glucocorticoid treatment.
    The Journal of veterinary medical science, 1997, Volume: 59, Issue:10

    Topics: Adrenal Cortex Hormones; Aging; Alkaline Phosphatase; Animals; Anti-Inflammatory Agents; Bone and Bo

1997
Dose uniformity of ophthalmic suspensions.
    Journal of cataract and refractive surgery, 1998, Volume: 24, Issue:5

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Aging; Anti-Inflammatory Agents; Anti-Infla

1998
Hearing in the MRL/lpr mouse as a possible model of immune-mediated sensorineural hearing loss.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 1998, Volume: 255, Issue:5

    Topics: Aging; Animals; Anti-Inflammatory Agents; Auditory Threshold; Autoimmune Diseases; Capillaries; Coch

1998
Inactivation and loss of antigenicity of esterase by sugars and a steroid.
    Biochimica et biophysica acta, 1999, Jul-07, Volume: 1454, Issue:2

    Topics: Aging; Carboxylesterase; Carboxylic Ester Hydrolases; Chromatography, Affinity; Diabetes Mellitus; E

1999
Sensitivity of bone remodeling markers in elderly male patients chronically treated with glucocorticoids.
    Journal of endocrinological investigation, 1999, Volume: 22, Issue:10 Suppl

    Topics: Adult; Aging; Alkaline Phosphatase; Biomarkers; Bone and Bones; Bone Remodeling; Glucocorticoids; Hu

1999
Osteoblastic 11beta-hydroxysteroid dehydrogenase type 1 activity increases with age and glucocorticoid exposure.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2002, Volume: 17, Issue:6

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Aging; Base Sequence; Cells, Cultured; DNA Primers; Glu

2002
[Development and maturation changes in DNA-and nitrogen content of mesenchymal and parenchymal organs with and without the influence of prednisolone (author's transl)].
    Aktuelle Gerontologie, 1979, Volume: 9, Issue:3

    Topics: Aging; Animals; Connective Tissue; DNA; Female; Kidney; Liver; Lung; Male; Nitrogen; Prednisolone; P

1979
Measurement of some viscoelastic properties of rat skin following repeated load.
    Connective tissue research, 1976, Volume: 4, Issue:3

    Topics: Aging; Animals; Elasticity; Male; Prednisolone; Rats; Skin; Skin Physiological Phenomena; Viscosity

1976
Influence of age and of desmotropic drugs on the step phenomenon observed in rat skin.
    Archives of dermatological research, 1979, Mar-31, Volume: 264, Issue:2

    Topics: Aging; Animals; Male; Penicillamine; Prednisolone; Rats; Skin; Skin Physiological Phenomena; Stress,

1979
Studies on osteoporosis I. Experimental models. Effect of age, sex, genetic background, diet, steroid and heparin treatment on calcium metabolism of mice.
    Research communications in chemical pathology and pharmacology, 1978, Volume: 22, Issue:1

    Topics: Aging; Animals; Calcium; Calcium Radioisotopes; Diet; Disease Models, Animal; Female; Heparin; Male;

1978
Strain of rat skin at constant load (creep experiments): influence of age and desmotropic agents.
    Gerontology, 1977, Volume: 23, Issue:2

    Topics: Aging; Animals; Female; Male; Penicillamine; Prednisolone; Rats; Skin Physiological Phenomena; Stres

1977
Tryptophan and serotonin metabolism in familial erythrophagocytic lymphohistiocytosis.
    Journal of inherited metabolic disease, 1992, Volume: 15, Issue:6

    Topics: Aging; Amino Acids; Biopterins; Child, Preschool; Etoposide; Histiocytosis, Non-Langerhans-Cell; Hom

1992
Stimulation of renal tubular transport of p-aminohippurate in rats of different ages by treatment with adrenocortical steroids.
    Developmental pharmacology and therapeutics, 1992, Volume: 19, Issue:1

    Topics: Adrenal Cortex Hormones; Aging; Animals; Dexamethasone; Female; In Vitro Techniques; Kidney Cortex;

1992
Acute bronchodilator trials in chronic obstructive pulmonary disease.
    The American review of respiratory disease, 1992, Volume: 146, Issue:3

    Topics: Aerosols; Aged; Aging; Albuterol; Bronchodilator Agents; Drug Evaluation; Female; Forced Expiratory

1992
Dynamics of circulating osteocalcin in rats during growth and under experimental conditions.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1992, Volume: 24, Issue:10

    Topics: Aging; Animals; Bone Development; Calcitriol; Calcium; Female; Lactation; Male; Osteocalcin; Ovariec

1992
Effect of swimming on prednisolone-induced osteoporosis in elderly rats.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1992, Volume: 7, Issue:2

    Topics: Aging; Animals; Body Water; Body Weight; Bone Density; Female; Ions; Magnetic Resonance Spectroscopy

1992
[Influence of various factors on glucocorticoid receptors of bronchoalveolar lavage (BAL) cells from rabbits].
    Nihon Kyobu Shikkan Gakkai zasshi, 1991, Volume: 29, Issue:7

    Topics: Aging; Animals; BCG Vaccine; Bronchoalveolar Lavage Fluid; Male; Nutrition Disorders; Prednisolone;

1991
The involvement of pineal gland and melatonin in immunity and aging. I. Thymus-mediated, immunoreconstituting and antiviral activity of thyrotropin-releasing hormone.
    Journal of neuroimmunology, 1990, Volume: 27, Issue:2-3

    Topics: Aging; Animals; Antibody Formation; Circadian Rhythm; Encephalomyocarditis virus; Female; Male; Mela

1990
Complete life cycle of the canid tapeworm, Echinococcus multilocularis, in laboratory rodents.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1990, Volume: 4, Issue:15

    Topics: Aging; Animals; Arvicolinae; Cats; Dogs; Echinococcosis; Echinococcus; Female; Gerbillinae; Intestin

1990
Purine enzyme levels in rheumatoid arthritis.
    The Journal of rheumatology, 1985, Volume: 12, Issue:6

    Topics: 5'-Nucleotidase; Adenosine Deaminase; Adult; Aged; Aging; Anti-Inflammatory Agents; Arthritis, Rheum

1985
Growth and endocrine function after renal transplantation.
    Archives of disease in childhood, 1988, Volume: 63, Issue:11

    Topics: Adolescent; Aging; Body Height; Child; Female; Hormones; Humans; Immunosuppressive Agents; Kidney Tr

1988
The effect of cyclosporine A on renal graft function is dependent on donor age.
    Transplantation proceedings, 1988, Volume: 20, Issue:3 Suppl 3

    Topics: Aging; Azathioprine; Cyclosporins; Humans; Kidney; Kidney Diseases; Kidney Transplantation; Predniso

1988
Improved results using pediatric cadaver donor kidneys with cyclosporine immunosuppression.
    Transplantation proceedings, 1988, Volume: 20, Issue:3 Suppl 3

    Topics: Aging; Antilymphocyte Serum; Azathioprine; Child, Preschool; Cyclosporins; Drug Administration Sched

1988
Immunological recovery after bone marrow transplantation: role of age, graft-versus-host disease, prednisolone treatment and infections.
    Bone marrow transplantation, 1987, Volume: 1, Issue:3

    Topics: Adolescent; Adult; Aging; Bone Marrow Transplantation; Child; Child, Preschool; Dose-Response Relati

1987
Kinetics of prednisolone and endogenous cortisol suppression in the elderly.
    Clinical pharmacology and therapeutics, 1988, Volume: 43, Issue:4

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Aging; Chromatography, High Pressure Liquid; F

1988
Effect of corticosteroid on porcine leukocytes: age-related effects of corticosteroid inhibition on porcine lymphocyte responses to mitogens.
    Veterinary immunology and immunopathology, 1986, Volume: 13, Issue:1-2

    Topics: Aging; Animals; Animals, Newborn; Dexamethasone; Kinetics; Lymphocyte Activation; Lymphocytes; Phyto

1986
Variation in serum type III procollagen peptide with age in healthy subjects and its comparative value in the assessment of disease activity in children and adults with chronic active hepatitis.
    European journal of clinical investigation, 1985, Volume: 15, Issue:2

    Topics: Adolescent; Adult; Aged; Aging; Azathioprine; Child; Child, Preschool; Hepatitis, Chronic; Humans; I

1985
Long-term action of prednisolone phosphate on a strain of short-lived mice.
    Experimental gerontology, 1968, Volume: 3, Issue:4

    Topics: Adenosine Triphosphatases; Aging; Animals; Animals, Newborn; Calcium; Collagen; Female; Femur; Growt

1968
The effect of ageing upon collagen metabolism.
    Symposia of the Society for Experimental Biology, 1967, Volume: 21

    Topics: Aging; Animals; Body Weight; Burns; Citrates; Collagen; Cycloheximide; Desoxycorticosterone; Glycine

1967
Corticosteroid osteoporosis.
    Clinics in endocrinology and metabolism, 1973, Volume: 2, Issue:2

    Topics: Adult; Aged; Aging; Arthritis, Rheumatoid; Asthma; Autoanalysis; Bone and Bones; Calcium; Calcium Ra

1973
Influence of age, treatment with corticosteroids and strain rate on mechanical properties of rat skin.
    Biochimica et biophysica acta, 1972, Nov-24, Volume: 286, Issue:1

    Topics: Aging; Animals; Body Weight; Elasticity; Kinetics; Male; Prednisolone; Rats; Skin Physiological Phen

1972
[Age associated factor in the risk of tumor development].
    Voprosy onkologii, 1973, Volume: 19, Issue:5

    Topics: Adult; Aging; Animals; Birth Weight; Body Weight; Carcinogens; Dexamethasone; Diet; Estrogens; Femal

1973
[Geriatric aspects of bronchopulmonary diseases].
    Fortschritte der Medizin, 1972, Jul-06, Volume: 90, Issue:19

    Topics: Aged; Aging; Anti-Bacterial Agents; Asthma; Bronchial Diseases; Bronchial Neoplasms; Bronchitis; Bro

1972
[Nephrotic syndrome as a leading symptom of glomerulonephritis in the aging man].
    Medizinische Klinik, 1970, Dec-25, Volume: 65, Issue:52

    Topics: Aging; Basement Membrane; Glomerulonephritis; Humans; Kidney Diseases; Nephrotic Syndrome; Prednisol

1970
[The functional status of the adrenal cortex in healthy and hemolytic newborn infants].
    Voprosy okhrany materinstva i detstva, 1967, Volume: 12, Issue:1

    Topics: 17-Ketosteroids; Adrenal Glands; Aging; Blood Transfusion; Cortisone; Erythroblastosis, Fetal; Femal

1967
The temperature-reversible cation shift of the lens.
    Transactions of the American Ophthalmological Society, 1966, Volume: 64

    Topics: Aging; Animals; Biological Transport; Calcium; Cataract; Cortisone; Dexamethasone; Glucose; Hydrocor

1966