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prednisolone and Acute Lymphoid Leukemia

prednisolone has been researched along with Acute Lymphoid Leukemia in 338 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Research Excerpts

ExcerptRelevanceReference
"In order to determine the clinically optimal dose of KRN8602, a new anthracycline derivative, in combination therapy for acute leukemia, we performed a pilot late phase II study in combination with cytarabine (Ara-C) for acute myelogenous leukemia (AML), and with vincristine (VCR) and prednisolone (PSL) for acute lymphocytic leukemia (ALL)."5.09[Pilot late phase II study of KRN8602 (MX2), a novel anthracycline derivative, for acute leukemia--a dose finding study in combination]. ( Hiraoka, A; Kuraishi, Y; Ogawa, M; Okabe, K; Sampi, K; Takemoto, Y; Tamura, K, 1999)
" She was diagnosed with myocarditis and successfully treated using prednisolone."5.05Myocarditis with Advanced Atrioventricular Block after Allogeneic Stem Cell Transplantation: A Case Report and Literature Review. ( Hiroshima, Y; Kazumoto, H; Kirihara, T; Kitahara, M; Kobayashi, H; Sato, K; Shimizu, K; Shishido, T; Sumi, M; Ueki, T; Uematsu, N, 2020)
" Although he was treated with prednisolone and hydroxyurea, marked eosinophilia persisted and lymphoblasts gradually increased in the bone marrow."4.78Hypereosinophilic syndrome evolving to acute lymphoblastic leukemia. ( Sanada, M; Takai, K, 1991)
" The patient had been administered steroid and cyclosporine for chronic graft-versus-host disease."3.77[Acute lymphoblastic leukemia complicated with varicella zoster virus meningoencephalitis and visceral dissemination after related bone marrow transplantation]. ( Inagaki, J; Nagatoshi, Y; Nomura, Y; Okamura, J; Sakiyama, M; Teranishi, H; Yanai, F, 2011)
" On the contrary, there is only one report of VOD during induction therapy for acute lymphoblastic leukemia in a patient with Marfan syndrome, who was successfully treated with defibrotide [2]."3.74Veno-occlusive disease of the liver during induction therapy for acute lymphoblastic leukemia. ( Diamantidis, MD; Girtovitis, F; Hatzitolios, A; Kaiafa, G; Kontoninas, Z; Ntaios, G; Papadopoulos, A; Saouli, Z; Savopoulos, C, 2008)
" The purpose of this study was to assess the incidence of adrenal insufficiency and the time for children with ALL to recover after treatment with the glucorticoids prednisolone or dexamethasone."3.72Impaired adrenal function after glucocorticoid therapy in children with acute lymphoblastic leukemia. ( Müller, J; Petersen, KB; Rasmussen, M; Schmiegelow, K, 2003)
"Serum levels of IgG subclasses were analysed in 15 children with acute lymphoblastic leukemia (ALL) receiving maintenance chemotherapy and 10 children with aplastic anemia and autoimmune diseases receiving prednisolone therapy longer than 2 months (Steroid group)."3.68[Effects of immunosuppressive chemotherapy on serum levels of IgG subclasses--analysis in children with acute lymphoblastic leukemia and in children with aplastic anemia and autoimmune diseases receiving corticosteroid hormone]. ( Fujieda, M; Hisakawa, H; Kubota, H; Kurashige, T; Matsumoto, K; Wakiguchi, H, 1990)
" A population pharmacokinetic model was developed and post hoc area under the curve (AUC) was tested against treatment outcome parameters."3.01Evaluation of the pharmacokinetics of prednisolone in paediatric patients with acute lymphoblastic leukaemia treated according to Dutch Childhood Oncology Group protocols and its relation to treatment response. ( Bierings, MB; de Haas, V; Kaspers, GJL; Mathôt, RAA; Pieters, R; Sassen, SDT; Te Loo, DMWW; Tissing, WJE; van den Bos, C; van der Sluis, IM; Zwaan, CM, 2021)
"The outcome for pediatric acute lymphoblastic leukemia (ALL) patients who relapse is dismal."2.80MAPK signaling cascades mediate distinct glucocorticoid resistance mechanisms in pediatric leukemia. ( Bhatla, T; Bitterman, DS; Bourgeois, W; Bride, K; Burleson, TM; Carroll, WL; Dandekar, S; de Rijk, SR; Delgado-Martin, C; Evensen, NA; Fosmire, S; Garabedian, MJ; Gearheart, CM; Hermiston, ML; Hunger, SP; Jones, CL; Loh, ML; Madhusoodhan, PP; Müschen, M; Pais, F; Park, E; Porter, CC; Raetz, EA; Teachey, DT; Waanders, AJ; Wang, J; Zhang, J, 2015)
"A total of 1947 patients with acute lymphoblastic leukemia were randomized."2.79Dexamethasone (6 mg/m2/day) and prednisolone (60 mg/m2/day) were equally effective as induction therapy for childhood acute lymphoblastic leukemia in the EORTC CLG 58951 randomized trial. ( Benoit, Y; Bertrandfor, Y; Cavé, H; Dastugue, N; De Moerloose, B; Domenech, C; Ferster, A; Girard, S; Lutz, P; Mazingue, F; Millot, F; Munzer, M; Philippet, P; Plantaz, D; Plat, G; Röhrlich, P; Sirvent, N; Suciu, S; Uyttebroeck, A; Yakouben, K, 2014)
"Infants (<366 days of age) with acute lymphoblastic leukemia (ALL) have a poor prognosis."2.77Modifications to induction therapy decrease risk of early death in infants with acute lymphoblastic leukemia treated on Children's Oncology Group P9407. ( Camitta, B; Carroll, WL; Devidas, M; Dreyer, ZE; Hilden, JM; Hunger, S; Jones, TL; Salzer, WL; Winick, N, 2012)
"Four clinically important acute lymphoblastic leukemia cell lines, three PRED-sensitive (697, Sup-B15, and RS4;11) and one PRED-resistant (REH) were studied."2.76BIM is a prognostic biomarker for early prednisolone response in pediatric acute lymphoblastic leukemia. ( Ariffin, H; Chew, FT; Jiang, N; Kham, SK; Koh, GS; Lim, JY; Yeoh, AE, 2011)
"The current randomized comparisons in childhood ALL indicated a statistically significant and clinically important decrease in rate of isolated central nervous system (CNS) relapses and an increase in event-free survival (EFS) with DXM."2.75Which steroids should we choose for the treatment of adult acute lymphoblastic leukemia? ( Cai, X; Liu, X; Sun, Z; Wu, J; Zheng, C; Zhu, W, 2010)
"Adult patients with acute lymphoblastic leukemia or lymphoblastic lymphoma were randomized to receive, as part of their induction therapy on days 1-8 and 15-22, either dexamethasone 8 mg/m(2) or prednisolone 60 mg/m(2)."2.75Dexamethasone compared to prednisolone for adults with acute lymphoblastic leukemia or lymphoblastic lymphoma: final results of the ALL-4 randomized, phase III trial of the EORTC Leukemia Group. ( Amadori, S; Berneman, Z; Bron, D; De Bock, R; de Witte, T; Feremans, W; Fillet, G; Gilotay, C; Jaksic, B; Labar, B; Marie, JP; Mistrik, M; Muus, P; Nemet, D; Sinnige, H; Suciu, S; Vreugdenhil, G; Willemze, R, 2010)
"Availability of measurement of minimal residual disease (MRD) at an early time point with a reduced-cost method is of clinical relevance."2.74Risk of relapse of childhood acute lymphoblastic leukemia is predicted by flow cytometric measurement of residual disease on day 15 bone marrow. ( Arico, M; Basso, G; Benetello, A; Biondi, A; Buldini, B; Conter, V; Dworzak, MN; Gaipa, G; Maglia, O; Masera, G; Ratei, R; Silvestri, D; Valsecchi, MG; Veltroni, M, 2009)
"Our study included 37 patients with acute lymphoblastic leukemia (ALL) and 11 patients with Morbus Hodgkin (MH) disease, who were treated with high-dose glucocorticoid therapy, and 26 control patients with other types of malignancies."2.73Glucocorticoids in the treatment of children with acute lymphoblastic leukemia and hodgkin's disease: a pilot study on the adverse psychological reactions and possible associations with neurobiological, endocrine, and genetic markers. ( Aschenbrenner, C; Baumgartner, M; Bieglmayer, C; Dworzak, M; Felder-Puig, R; Gadner, H; Koper, JW; Nasel, C; Ortner, M; Panzer-Grümayer, ER; Scherzer, C; Steinberger, K; Tissing, WJ; Topf, R; Voigtländer, T, 2007)
" There is increasing evidence that, even in equipotent dosage for glucocorticoid effect, dexamethasone has enhanced lymphoblast cytotoxicity and penetration of the central nervous system (CNS) compared with prednisolone."2.71Benefit of dexamethasone compared with prednisolone for childhood acute lymphoblastic leukaemia: results of the UK Medical Research Council ALL97 randomized trial. ( Eden, TO; Kinsey, SE; Lilleyman, J; Mitchell, CD; Richards, SM; Vora, A, 2005)
"A two-compartment pharmacokinetic model was used to describe data from 23 children with ALL (aged 2-15 years)."2.71Population pharmacokinetics of prednisolone in children with acute lymphoblastic leukemia. ( Jusko, WJ; Petersen, KB; Rasmussen, M; Schmiegelow, K, 2003)
"The leptin : SHBG ratio increase indicates that this may be a novel and sensitive biochemical marker of metabolic change."2.71Short-term effects of prednisolone and dexamethasone on circulating concentrations of leptin and sex hormone-binding globulin in children being treated for acute lymphoblastic leukaemia. ( Ahmed, SF; Hughes, IA; Tucker, P; Wallace, AM; Williams, DM, 2003)
"We investigated whether there was a dose-response relationship for the use of corticosteroids in childhood acute lymphoblastic leukemia (ALL)."2.70Improved response with higher corticosteroid dose in children with acute lymphoblastic leukemia. ( Chilton, D; Cohen, HJ; Gelber, RD; Sallan, SE; Schwartz, CL; Thompson, EB; Young, ML, 2001)
"In a prior study, primary resistant acute lymphoblastic leukemia (RES-ALL) was observed in 11 of 176 (6%) adult patients treated with a four drug regimen (IVAP), its incidence being higher in T-cell or Philadelphia (Ph) chromosome/BCR-ABL rearrangement positive ALL cases with a blast cell count >25x10(9)/L (RES-ALL rate 19%, p=0."2.69Fractionated cyclophosphamide added to the IVAP regimen (idarubicin-vincristine-L-asparaginase-prednisone) could lower the risk of primary refractory disease in T-lineage but not B-lineage acute lymphoblastic leukemia: first results from a phase II clinic ( Barbui, T; Bassan, R; Casula, P; Corneo, G; Coser, P; Fabris, P; Izzi, T; Lambertenghi-Deliliers, G; Lerede, T; Morandi, S; Pogliani, E; Rossi, G; Vespignani, M, 1999)
"Patients with acute lymphocytic leukemia (ALL) and those with lymphoblastic lymphoma (LBL) have overlapping clinical and immunophenotypic features and they have been treated with the same or very similar chemotherapy regimens."2.69Long-term follow-up results of adult patients with acute lymphocytic leukemia or lymphoblastic lymphoma treated with short-term, alternating non-cross-resistant chemotherapy: Japan Clinical Oncology Group Study 8702. Lymphoma Study Group. ( Abe, T; Aoki, I; Araki, K; Deura, K; Fukuda, H; Fukuhara, S; Hotta, T; Kobayashi, T; Konda, S; Kozuru, M; Matsumoto, M; Mikuni, C; Nagai, M; Niimi, M; Oyama, A; Sai, T; Shimoyama, M; Shirakawa, S; Tajima, K; Tobinai, K; Toki, H; Yamaguchi, N, 1999)
"Hyperglycemia in children with acute lymphoblastic leukemia (ALL) has been well documented in the literature."2.69Clinical value of glycated hemoglobin and fructosamine in the long-term glycemic control of children with acute lymphoblastic leukemia. ( Ozbek, N; Yalçin, SS; Yetgin, S, 1998)
"In children with acute lymphoblastic leukemia (ALL), the level of minimal residual disease (MRD) at the end of induction strongly predicts outcome, presumably because it measures both drug sensitivity and the number of leukemic cells requiring elimination."2.68Relationship between minimal residual disease and outcome in adult acute lymphoblastic leukemia. ( Bradstock, K; Brisco, J; Enno, A; Hughes, E; McCaul, K; Morley, AA; Neoh, SH; Sykes, PJ; Szer, J, 1996)
"Idarubicin was preferred to other anthracyclines because of its shorter time to response."2.68Age-adapted moderate-dose induction and flexible outpatient postremission therapy for elderly patients with acute lymphoblastic leukemia. ( Barbui, T; Bassan, R; Buelli, M; D'Emilio, A; Di Bona, E; Lerede, T; Pogliani, E; Rambaldi, A; Rodeghiero, F; Rossi, G; Viero, P, 1996)
"Twelve adult patients with non-leukaemic lymphoblastic lymphoma were treated with combination chemotherapy and central nervous system prophylaxis according to the protocol developed at Stanford University."2.67Adult lymphoblastic lymphoma: high incidence of central nervous system relapse in patients treated with the Stanford University protocol. ( Mead, GM; Sweetenham, JW; Whitehouse, JM, 1992)
"The treatment of children with acute lymphoblastic leukemia was conducted with the use of 06-Paris-LA-66 program modified by the authors."2.67[Results of 16-year use of the 06-Paris-LA-66 program in the treatment of children with acute lymphoblastic leukemia]. ( Kovrigina, TI; Mendeleev, IM; Polezhaev, IuN, 1991)
"Sixty-one consecutive patients with acute lymphoblastic leukemia (ALL) (B-ALL excluded) were treated with the protocol described by Hoelzer et al."2.67High efficacy of the German multicenter ALL (GMALL) protocol for treatment of adult acute lymphoblastic leukemia (ALL)--a single-institution study. ( Bettelheim, P; Geissler, K; Jäger, U; Knöbl, P; Kyrle, PA; Laczika, K; Mitterbauer, G; Neumann, E; Scherrer, R; Schneider, B, 1994)
"A total of 42 adults with acute lymphoblastic leukemia were treated with an aggressive induction/consolidation chemotherapy (MCP-841) between June 1986 and December 1991."2.67Adult acute lymphoblastic leukemia: results of an aggressive regimen in India. ( Advani, IM; Gopal, R; Nadkarni, K; Pai, S; Pai, V; Parikh, P; Raje, N; Saikia, T; Vaidya, S, 1994)
"Prednisolone is a corticosteroid and one of the most important agents in the treatment of acute lymphoblastic leukemia."2.66Gene Expression and Resistance to Glucocorticoid-Induced Apoptosis in Acute Lymphoblastic Leukemia: A Brief Review and Update. ( Adamaki, M; Hatziagapiou, K; Lambrou, GI; Vlahopoulos, S, 2020)
"We report a case of de novo acute lymphoblastic leukemia with tandem amplification of the AML1 gene located in a chromosome marker that originated from chromosome 21 and a long event-free survival."2.42AML1 amplification in a child with acute lymphoblastic leukemia. ( Alvarez, Y; Bastida, P; Caballín, MR; Coll, MD; Ortega, JJ, 2003)
"Even though acute lymphoblastic leukemia (ALL) responds well to chemotherapy, relapse remains the major problem."2.41Low relapse rate in children with acute lymphoblastic leukemia after risk-directed therapy. ( Botsonis, A; Moschovi, M; Papadopoulou, AL; Tsangaris, GT; Tzortzatou-Stathopoulou, F, 2001)
"Congestive heart failure was observed in only 2."2.41Long-term outcome of treatment with protocols AL841, AL851, and ALHR88 in children with acute lymphoblastic leukemia: results obtained by the Kyushu-Yamaguchi Children's Cancer Study Group. ( Akiyoshi, K; Eguchi, H; Hara, T; Inada, H; Ishii, E; Koga, H; Matsuzaki, A; Miyazaki, S; Nagatoshi, Y; Nakayama, H; Nibu, K; Okamura, J; Take, H; Tamai, Y; Yanai, F, 2001)
"This favorable response with the ANLL-9205 protocol was mainly to high induction rate of patients with the M4 and M5 subtypes, as compared to those in the previous two protocols."2.40[Recent advances on the treatment of acute childhood leukemia]. ( Fujimoto, T, 1997)
"However, the results of acute lymphoblastic leukemia in the JALSG ALL 87 study were not satisfactory; 84% CR in 116 adults and only 24% 6-year DFS."2.39[Progress of chemotherapy in adult acute leukemia]. ( Ohno, R, 1995)
"We report here a patient with acute lymphoblastic leukemia (ALL) in whom hypofibrinogenemia developed during chemotherapy."2.38[Transient hypofibrinogenemia induced by prednisolone in a case of acute lymphoblastic leukemia]. ( Baba, Y; Fujieda, H; Hojo, H; Ohyashiki, JH; Ohyashiki, K; Toyama, K, 1989)
"Prednisolone is a corticosteroid and one of the most important agents in the treatment of ALL."1.62Early and Very Early GRIM19 and MCL1 Expression Are Correlated to Late Acquired Prednisolone Effects in a T-Cell Acute Leukemia Cell Line. ( Adamaki, M; G, L; Geronikolou, SA; Hatziagapiou, K; Tsartsalis, AN; Vlahopoulos, S, 2021)
"Adolescents and young adults (AYAs) with acute lymphoblastic leukemia (ALL) are more likely to have chemotherapy-related complications than children."1.62Comparison of myelosuppression using the D-index between children and adolescents/young adults with acute lymphoblastic leukemia during induction chemotherapy. ( Hori, D; Kobayashi, K; Kobayashi, R; Kodama, K; Matsushima, S; Sano, H; Suzuki, D; Yanagi, M, 2021)
"Prednisolone has been used frequently in the treatment of acute lymphoblastic leukemia."1.62Antileukemic Effects of Anti-miR-146a, Anti-miR-155, Anti-miR-181a, and Prednisolone on Childhood Acute Lymphoblastic Leukemia. ( Aksoylar, S; Alpay, A; Bagca, BG; Cogulu, O; Durmaz, B; Gunduz, C; Susluer, SY, 2021)
"In childhood acute lymphoblastic leukemia, high treatment-related mortality, especially in the induction phase of treatment, is a major challenge for developing countries."1.56Prednisolone Prophase for a Week Versus Upfront Multiagent Chemotherapy in Childhood Acute Lymphoblastic Leukemia: An Analysis With Reference to Induction Mortality in a Developing Country. ( Ashraf, S; Butt, Z; Jabbar, N; Mansoor, N; Maqsood MSc, S; Nadeem, K, 2020)
"acute lymphoblastic leukemia-type chemotherapy that incorporated high-dose cytarabine was effective in achieving an minimal residual disease-negativity rate of 69% in evaluated patients, which was also predictive of better outcome."1.56Clinicoepidemiologic Profile and Outcome Predicted by Minimal Residual Disease in Children With Mixed-phenotype Acute Leukemia Treated on a Modified MCP-841 Protocol at a Tertiary Cancer Institute in India. ( Banavali, S; Gujral, S; Myint, HH; Narula, G; Patkar, N; Prasad, M; Subramanian, P; Tandon, S; Tembhare, P, 2020)
"Concerning hematological disorders, Sweet syndrome often presents in patients with myeloid diseases, but it is rarely observed in patients with lymphoid diseases."1.51[Recurring Sweet syndrome in a patient with Philadelphia chromosome-positive acute lymphoblastic leukemia]. ( Aoki, T; Ishihara, D; Kamimura, T; Umeno, T; Urata, S, 2019)
"Multivariate analysis revealed that minimal residual disease positive and time interval between induction IA and Protocol M of more than 70 days were independent adverse factors for EFS and OS."1.51Long-term outcomes of modified BFM-95 regimen in adults with newly diagnosed standard-risk acute lymphoblastic leukemia: a retrospective single-center study. ( Cai, X; Chen, X; Li, C; Liang, Y; Wang, H; Xia, Z, 2019)
"Histopathological subtypes consist of Burkitt's lymphoma (BL) in 32 (43."1.48Demographics and Outome in Paediatric Non-Hodgkin Lymphoma: Single Centre Experience at The Children Hospital Lahore, Pakistan. ( Anwar, S; Faizan, M; Khan, S, 2018)
"For children with precursor B (pre-B) acute lymphoblastic leukemia (ALL) with TCF3-PBX1 fusion gene, their prognosis has been a controversial topic."1.42Clinical features and prognostic significance of TCF3-PBX1 fusion gene in Chinese children with acute lymphoblastic leukemia by using a modified ALL-BFM-95 protocol. ( Chai, YH; Liang, Y; Pan, J; Pang, L; Wang, JR; Zhao, WL, 2015)
"Imatinib mesylate has dramatically improved the outcome of children with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph* ALL) and is now included as first-line therapy."1.42Imatinib-induced Severe Hepatitis in a 9-Year-old Girl With Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia. ( Fukushima, H; Fukushima, T; Kobayashi, C; Nanmoku, T; Sakai, A; Satomi, K; Sumazaki, R; Suzuki, R; Tagawa, M, 2015)
"To compare, for the first time, the in vitro antileukemic activity of prednisolone alone to that of a combination of prednisolone and dexamethasone using dexamethasone at a very low and presumably safe dosage (1/50 w/w)."1.40Combination of prednisolone and low dosed dexamethasone exhibits greater in vitro antileukemic activity than equiactive dose of prednisolone and overcomes prednisolone drug resistance in acute childhood lymphoblastic leukemia. ( Blazek, B; Bubanska, E; Burianova, R; Dzubak, P; Hajduch, M; Hak, J; Kaiserova, E; Konecny, P; Mihal, V; Novak, Z; Pospisilova, D; Radova, L; Salkova, S; Spenerova, M; Srovnal, J; Stary, J; Timr, P; Votava, T, 2014)
"We found that nasolacrimal duct obstruction did not improve with medical treatment but ptosis and esotropia improved with pyridoxine and pyridostigmine treatment during that period."1.39Nasolacrimal system obstruction, ptosis and esotropia due to chemotherapy in acute lymphoblastic leukemia. ( Burakgazi-Dalkilic, E; Esmer, O; Karadag, R; Oner, AF; Soylu, E, 2013)
"MLL-rearranged infant acute lymphoblastic leukemia (ALL) (<1 year of age) are frequently resistant to glucocorticoids, like prednisone and dexamethasone."1.39Src kinase-induced phosphorylation of annexin A2 mediates glucocorticoid resistance in MLL-rearranged infant acute lymphoblastic leukemia. ( Mimoso Pinhanços, S; Pieters, R; Schneider, P; Spijkers-Hagelstein, JA; Stam, RW, 2013)
"At 4 years old he was diagnosed with acute lymphoblastic leukemia and underwent bone marrow transplantation."1.38Early occurrence of nephrotic syndrome associated with cord blood stem cell transplantation. ( Furuya, A; Ida, K; Igarashi, T; Koh, K; Miura, K; Sekine, T; Takamizawa, M; Takita, J; Terashima, H, 2012)
"MLL-rearranged acute lymphoblastic leukemia (ALL) in infants is characterized by a poor clinical outcome and resistance to glucocorticoids (for example, prednisone and dexamethasone)."1.38Elevated S100A8/S100A9 expression causes glucocorticoid resistance in MLL-rearranged infant acute lymphoblastic leukemia. ( de Boer, J; Hulleman, E; Pieters, R; Schneider, P; Spijkers-Hagelstein, JA; Stam, RW; Williams, O, 2012)
"Spinal cord compression is a rare complication of acute lymphoblastic leukemia (ALL)."1.37Spinal cord compression by epidural involvement over 21 vertebral levels in acute lymphoblastic leukemia. ( Fukaya, T; Isome, K; Iwata, A; Matsubara, K; Nigami, H; Taki, T; Taniwaki, M; Wada, T; Yura, K, 2011)
"A patient with relapsed Acute Lymphoblastic Leukemia and recurrent pericardial effusion presented."1.37Intrapericardial steroid treatment for recurrent pericardial effusion in a patient with acute lymphoblastic Leukaemia. ( Hatib, I; Lorber, A; Mainzer, G; Zaidman, I, 2011)
"The renal biopsy showed type I membranoproliferative glomerulonephritis."1.36Membranoproliferative glomerulonephritis following allogeneic hematopoietic stem cell transplantation. ( Chang, YS; Chung, S; Kim, B; Kim, JY; Lee, MY; Park, CW, 2010)
"Obesity is increasingly prevalent in affluent societies and portends considerable morbidity."1.36Growth in children with acute lymphoblastic leukemia during treatment. ( Barr, RD; Collins, L; Nayiager, T; Pollock, BH; Zarzabal, LA, 2010)
"Good prednisolone response was observed in 82% of cases."1.35Treatment of children with acute lymphoblastic leukemia in India using a BFM protocol. ( Bajel, A; Chandy, M; George, B; Kavitha, ML; Mathews, V; Srivastava, A; Viswabandya, A, 2008)
"Chemotherapy-induced oral mucositis is a frequent therapeutic challenge in cancer patients."1.35Oral mucositis in acute lymphoblastic leukaemia: analysis of 169 paediatric patients. ( Figliolia, SL; Lauris, JR; Maurício, AR; Mello de Andrea, ML; Oliveira, DT; Pereira, MC, 2008)
"Treatment of prednisolone-resistant Jurkat and Molt4 cells with 2-deoxy-D-glucose (2-DG), lonidamine (LND), or 3-bromopyruvate (3-BrPA) increased the in vitro sensitivity to glucocorticoids, while treatment of the prednisolone-sensitive cell lines Tom-1 and RS4; 11 did not influence drug cytotoxicity."1.35Inhibition of glycolysis modulates prednisolone resistance in acute lymphoblastic leukemia cells. ( Broekhuis, MJ; Den Boer, ML; Evans, WE; Holleman, A; Hulleman, E; Kazemier, KM; Pieters, R; Rudin, CM; VanderWeele, DJ, 2009)
"Prednisolone resistance was higher in SMARCA4 shRNA-transfected Jurkat cells (drug concentration lethal to 50% of the leukemia cells [LC(50)] = 277 microM) than in control shRNA-transfected cells (LC(50) = 174 microM, difference = 103 microM, 95% confidence interval of the difference = 100 to 106 microM; P < ."1.35The SWI/SNF chromatin-remodeling complex and glucocorticoid resistance in acute lymphoblastic leukemia. ( Assem, M; Cheng, C; Cheok, MH; Den Boer, ML; Evans, WE; Panetta, JC; Paugh, SW; Pei, D; Pieters, R; Pottier, N; Relling, MV; Yang, W, 2008)
" All six patients received prophylactic cranial irradiation with a dosage of 18 or 24 Gy."1.34Moyamoya syndrome following childhood acute lymphoblastic leukemia. ( Hanada, R; Ikuta, K; Ishimoto, K; Kaneko, T; Kikuchi, A; Maeda, M; Okimoto, Y; Tsuchida, M, 2007)
"The treatment outcome of children with acute lymphoblastic leukemia improved remarkably over the last decades."1.33[Treatment results with ALL-BFM-95 protocol in children with acute lymphoblastic leukemia in Hungary]. ( Bartyik, K; Békési, A; Galántai, I; Jakab, Z; Kajtár, P; Kiss, C; Kovács, G; Magyarosy, E; Masát, P; Müller, J; Nagy, K; Rényi, I, 2005)
"Thalidomide is a drug with anti-angiogenic, anti-inflammatory, immunomodulatory and anti-cancer properties that were found to inhibit the production of TNF-alpha in vitro, stimulate reactive oxygen species production, and inhibit VEGFR in acute leukemias."1.33Ex vivo activity of thalidomide in childhood acute leukemia. ( Czyzewski, K; Styczynski, J; Wysocki, M, 2006)
"Superior sagittal sinus thrombosis (SSST) has been reported to be caused by coagulopathy following oral contraceptive therapy, DIC, infection around the sinus, compression from a tumor, infiltration of tumor, and an inherited deficiency of proteins C and S, but SSST associated with hematological malignancies and L-asparaginase (L-Asp) therapy is rare."1.33[Superior sagittal sinus thrombosis during remission induction therapy for acute lymphoblastic leukemia]. ( Iijima, K; Iki, S; Kida, M; Nakasone, H; Taoka, K; Urabe, A; Usuki, K; Yoshimi, A, 2006)
"Cellular sensitivity in acute lymphoblastic leukemia (ALL) was higher than in acute myeloid one (AML), while T-line ALL cells were more sensitive to dexamethasone than those of B-line."1.33[Drug sensitivity of tumor cells in varieties of acute childhood leukemia]. ( Belevtsev, MV; Buglova, SE; Shman, TV, 2005)
"GC resistance in childhood ALL cannot be attributed to an inability of resistant cells to up-regulate the expression of the GR upon GC exposure, nor to differences in GR promoter usage (at baseline and upon GC exposure)."1.33Glucocorticoid-induced glucocorticoid-receptor expression and promoter usage is not linked to glucocorticoid resistance in childhood ALL. ( Brinkhof, B; Broekhuis, MJ; den Boer, ML; Meijerink, JP; Menezes, RX; Pieters, R; Tissing, WJ, 2006)
"No increased frequency of infection was seen for the children with genotypes encoding serum low levels of MBL."1.33Infections during induction therapy of childhood acute lymphoblastic leukemia--no association to mannose-binding lectin deficiency. ( Andreassen, B; Garred, P; Lausen, B; Madsen, HO; Schmiegelow, K, 2006)
"Prednisolone treated patients had an increased percentage body fat (SDS +0."1.33No difference between prednisolone and dexamethasone treatment in bone mineral density and growth in long term survivors of childhood acute lymphoblastic leukemia. ( de Muinck Keizer-Schrama, SM; Hakvoort-Cammel, FG; Krenning, EP; Pieters, R; van Beek, RD; van den Heuvel-Eibrink, MM; van der Sluis, IM, 2006)
"Acute lymphoblastic leukemia (ALL) can be cured with combination chemotherapy in over 75% of children, but the cause of treatment failure in the remaining patients is unknown."1.33Identification of genes associated with chemotherapy crossresistance and treatment response in childhood acute lymphoblastic leukemia. ( Cheng, C; Cheok, MH; den Boer, ML; Evans, WE; Holleman, A; Janka-Schaub, GE; Lugthart, S; Pieters, R; Pui, CH; Relling, MV; Yang, W, 2005)
"Childhood acute lymphoblastic leukemia (ALL) is curable with chemotherapy in approximately 80 percent of patients."1.32Gene-expression patterns in drug-resistant acute lymphoblastic leukemia cells and response to treatment. ( Cheng, C; Cheok, MH; den Boer, ML; Evans, WE; Holleman, A; Janka-Schaub, GE; Kazemier, KM; Pei, D; Pieters, R; Pui, CH; Relling, MV; Veerman, AJ; Yang, W, 2004)
"A 9-year-old patient with leukemia received oral prednisolone at a dosage of 2."1.32Intraocular pressure profile of a child on a systemic corticosteroid. ( Chik, KW; Lam, DS; Li, RT; Ng, JS; Tham, CC, 2004)
"t(12;21)(p1 3;q22), the most frequent chromosomal translocation found in childhood acute lymphoblastic leukemia (ALL), occurs in approximately 25% of B-lineage ALL cases and has been claimed to carry a good prognosis."1.32Post-induction residual disease in translocation t(12;21)-positive childhood ALL. ( Clausen, N; Jonmundsson, GK; Madsen, HO; Nyvold, C; Ryder, LP; Schmiegelow, K; Seyfarth, J; Wesenberg, F, 2003)
"A 26-year-old male with acute lymphoblastic leukemia (ALL) in its second complete remission received an unrelated bone marrow transplantation (UBMT) following cyclophosphamide plus total body irradiation conditioning."1.31A successful second unrelated BMT (UBMT) from a different unrelated donor to treat ALL that relapsed after the initial UBMT. ( Nakaseko, C; Nishimura, M; Saito, Y; Uehara, T; Yokota, A, 2002)
"Most prognostic factors in childhood acute lymphoblastic leukemia (ALL) are informative for groups of patients, whereas new approaches are needed to predict the efficacy of chemotherapy for the individual patient."1.31Post-induction residual leukemia in childhood acute lymphoblastic leukemia quantified by PCR correlates with in vitro prednisolone resistance. ( Kaspers, GJ; Knabe, N; Madsen, HO; Nyvold, C; Pieters, R; Rottier, MM; Ryder, LP; Schmiegelow, K; Seyfarth, J; Svejgaard, A, 2001)
"The prognosis for DS acute myeloid leukemia (AML) is better than for non-DS AML, but the clinical outcome of DS acute lymphoblastic leukemia (ALL) is equal to that of non-DS ALL."1.31Different drug sensitivity profiles of acute myeloid and lymphoblastic leukemia and normal peripheral blood mononuclear cells in children with and without Down syndrome. ( Creutzig, U; de Vries, E; Hählen, K; Huismans, DR; Janka-Schaub, GE; Jansen, G; Kaspers, GJ; Peters, GJ; Pieters, R; Rots, MG; van Zantwijk, CH; Veerman, AJ; Zwaan, CM, 2002)
"Treatment failure in newly diagnosed childhood ALL can be predicted based on cellular drug resistance data."1.30In vitro cellular drug resistance and prognosis in newly diagnosed childhood acute lymphoblastic leukemia. ( Kaspers, GJ; Pieters, R; Smets, LA; Van Der Does-Van Den Berg, A; Van Wering, ER; Van Zantwijk, CH; Veerman, AJ, 1997)
"There were 55 patients with acute myelogenous leukemia (AML), 13 acute lymphoblastic leukemia (ALL) and 8 AML from myelodysplastic syndrome (MDS/AML)."1.30[Retrospective analysis of elderly patients > or = 60 years of age with acute leukemia]. ( Amemiya, Y; Furukawa, Y; Hoshino, M; Imagawa, S; Izumi, T; Kawano, C; Kirito, K; Komatsu, N; Kuribara, R; Miura, Y; Miyazato, A; Muroi, K; Omine, K; Otsuki, T; Shimizu, R; Suzuki, T; Tabata, M; Takahashi, H; Takatoku, M; Terui, Y; Tomizuka, H; Toshima, M; Tsunoda, J; Uchida, M; Yoshida, M, 1998)
"Acute lymphoblastic leukemia (L3) was initially diagnosed because of poor staining of alpha-naphtyl butylate esterase and induction chemotherapy with the LVP regimen (L-asparaginase 5,000 U/m2 day 8-21, vincristine 1."1.30[Complete remission achieved by L-asparaginase, vincristine and prednisolone (LVP) therapy in secondary leukemia (M5a type) with an MLL gene rearrangement]. ( Fujita, H; Kobayashi, S; Kodama, F; Koharazawa, H; Maruta, A; Okubo, T; Tomita, N; Yamamoto, T, 1997)
" After initial chemotherapy, he received intravenous methotrexate (total dosage 1,035 mg), intrathecal methotrexate (total dosage 221 mg), and whole brain irradiation (2,400 cGy)."1.29Lenńox-Gastaut syndrome associated with leukoencephalopathy. ( Ikuta, H; Mitsufuji, N; Sawada, T; Yoshioka, H, 1996)
"Ten months after referral, she developed acute lymphoblastic leukemia (FAB classification; L1)."1.29Acute lymphoblastic leukemia in Ehlers-Danlos syndrome. ( Asano, T; Yamamoto, M, 1996)
" This finding may serve to guide the selection of dexamethasone dosage in the treatment of ALL."1.29Comparative cytotoxicity of dexamethasone and prednisolone in childhood acute lymphoblastic leukemia. ( Campana, D; Coustan-Smith, E; Evans, WE; Ito, C; Mahmoud, H; McNinch, L; Pui, CH, 1996)
"Results of clinical studies of childhood acute lymphoblastic leukemia (ALL) suggested that DXM is more potent relative to PRD than assumed."1.29Comparison of the antileukemic activity in vitro of dexamethasone and prednisolone in childhood acute lymphoblastic leukemia. ( Kaspers, GJ; Lomecky, M; Pieters, R; Popp-Snijders, C; Swinkels, LM; Van Wering, ER; Van Zantwijk, CH; Veerman, AJ, 1996)
"From 1975 to 1989, 71 acute lymphoblastic leukemia patients aged 15 to 81 years (median 46 years) were treated at Jichi Medical School."1.29[Treatment of 71 adult acute lymphoblastic leukemia]. ( Akutsu, M; Furukawa, Y; Imagawa, S; Iwama, A; Komatsu, N; Kurata, H; Suzuki, T; Tsunoda, J; Tsunoda, S; Yoshida, M, 1993)
"Late-relapse was more frequently observed in boys (37."1.29[Treatment and prognosis after late relapse in childhood acute lymphoblastic leukemia]. ( Fujioka, K; Funabiki, T; Hanzawa, N; Ikuta, K; Kai, S; Kajigaya, Y; Okuyama, T; Sekiguchi, H; Sumita, H; Takahashi, H, 1993)
"When patients with common acute lymphoblastic leukemia (cALL) and acute myeloblastic leukemia (AML) were treated with prednisolone (60 mg/m2/day, p."1.29Induction of apoptosis in childhood acute leukemia by chemotherapeutic agents: failure to detect evidence of apoptosis in vivo. ( Adachi, S; Akiyama, Y; Hirota, H; Kubota, M; Kuwakado, K; Matsubara, K; Mikawa, H; Wakazono, Y, 1994)
" The type of interaction was different between patients, and depends on the drug combination and concentrations."1.29Drug combination testing in acute lymphoblastic leukemia using the MTT assay. ( Hählen, K; Kaspers, GJ; Pieters, R; Van Wering, ER; Van Zantwijk, I; Veerman, AJ, 1995)
"Information about elderly patients with acute lymphoblastic leukemia is scarce."1.28[Treatment of elderly patients with hematological malignancies]. ( Mizoguchi, H; Saito, H, 1992)
"The complete remission (CR) rate of ANLL was 90."1.28[Evaluation of 58 patients with acute leukemia]. ( Sasaki, A; Tsukaguchi, M, 1992)
"After 5 months, diagnosis of acute lymphocytic leukemia (ALL) was made on the evidence that lymphoblasts were found in PB (1%) and in BM (98%)."1.28[Acute lymphocytic leukemia (L1) preceded by hypercalcemia]. ( Ishizaki, J; Kawano, K; Maeda, K; Maruyama, H; Matsuoka, H; Tamaki, N; Tsuda, K; Uno, H; Yamashita, R, 1992)
"For prednisolone there was a significant worsening of the prognosis (p less than 0."1.28Relation of cellular drug resistance to long-term clinical outcome in childhood acute lymphoblastic leukaemia. ( Hählen, K; Huismans, DR; Loonen, AH; Pieters, R; van der Does-van den Berg, A; van Wering, ER; Veerman, AJ, 1991)
"Twenty-nine adult patients with acute lymphocytic leukemia (ALL) were treated with combination chemotherapy consisting of behenoyl-ara-C, adriamycin, cyclophosphamide, vindesine and prednisolone (BHAC-ACVP regimen)."1.28[A study of combination chemotherapy (BHAC-ACVP) for adult acute lymphocytic leukemia. Hanshin Co-operative Study Group of Hematological Malignancies]. ( Horiuchi, A; Kageyama, T; Kakishita, E; Kanamaru, A; Kawagoe, H; Kitani, T; Masaoka, T; Nagai, K; Tatsumi, N; Yasunaga, K, 1992)
" An animal model is presented to assess these adverse effects on growth."1.28An animal model to study toxicity of central nervous system therapy for childhood acute lymphoblastic leukemia: effects on growth and craniofacial proportion. ( Howes, A; Mullenix, PJ; Schunior, A; Tarbell, NJ; Tassinari, MS; Zengel, AE, 1990)
"A 38-year-old female with acute lymphoblastic leukemia developed monoplegia of the left upper extremity following chemotherapy for remission induction consisting of vincristine, prednisolone, cyclophosphamide, adriamycin and methotrexate."1.28[Transient dysfibrinogenemia and cerebral thrombosis following remission induction therapy for acute lymphoblastic leukemia]. ( Harada, M; Hayashi, S; Kubota, T; Nagafuchi, S; Niho, Y; Ohtsuka, T; Okamura, T; Shibuya, T, 1990)
"The use of azathioprine in ulcerative colitis is unclear."1.28The role of azathioprine in the management of ulcerative colitis. ( Axon, AT; Burke, DA; Foster, PN; Johnston, D; Lobo, AJ, 1990)
"Pretreatment with prednisolone was started as therapy for leukemia, and 2 days later, the patient underwent surgery."1.28Intestinal obstruction at the onset of acute lymphoblastic leukemia in a child. ( Ballati, G; Cozzi, F; Digilio, G; Iacobini, M; Lemmo, M; Multari, G; Roggini, M; Sirignano, A; Werner, B, 1990)
"An 11 year-old girl was diagnosed as acute lymphoblastic leukemia (ALL) on November 26th 1979 and was induced into complete remission with vincristine and prednisolon."1.28[Long-term surviving child with acute lymphoblastic leukemia complicated with legionellosis]. ( Nakura, E; Ohno, R; Saito, H; Tanabe, N, 1990)
"Eighteen adults with acute lymphoblastic leukemia (ALL) including 14 previously untreated and 4 relapsed cases were treated with individualized and intensified induction and post-remission therapy."1.28[Multi-agent combination chemotherapy for adult acute lymphoblastic leukemia--individualized chemotherapy]. ( Ito, T; Komatsu, M; Saito, Y; Takahashi, H; Toyota, T; Uzuka, Y, 1990)
"Since April, 1978 to October, 1988, 66 acute lymphocytic leukemia (ALL) patients aged 15 to 79 (21 L1, 43 L2, 2 L3/6 Ph1+) were treated with 3 different therapeutic protocols."1.28[Treatment of acute lymphocytic leukemia in adult]. ( Hayashi, N; Inagaki, N; Matuzaki, T; Nakada, H; Nishimura, M; Nonaka, K; Osada, K; Sekito, N; Takahashi, I; Takeuchi, M, 1989)
" For total prednisolone, the mean elimination half-life was relatively short (1."1.28Pharmacokinetics of prednisolone in children with acute lymphoblastic leukaemia. ( Blackburn, M; Choonara, I; Lewis, I; Rayner, P; Wheeldon, J, 1989)
"They were ALL(6), ANLL(8), CML(1) and NHL(1)."1.27[BH-AC.AMP protocol in the treatment of refractory childhood acute leukemia]. ( Hatae, Y; Hatayama, Y; Nakadate, H; Takeda, T, 1988)
"20 consecutive adult patients with acute lymphoblastic leukemia were treated with an intense induction regimen including vincristine, doxorubicin, prednisolone, L-asparaginase and cyclophosphamide."1.27Aggressive treatment improves survival in adult acute lymphoblastic leukemia. ( Killander, A; Simonsson, B; Smedmyr, B; Sundström, C, 1988)

Research

Studies (338)

TimeframeStudies, this research(%)All Research%
pre-199015 (4.44)18.7374
1990's122 (36.09)18.2507
2000's105 (31.07)29.6817
2010's78 (23.08)24.3611
2020's18 (5.33)2.80

Authors

AuthorsStudies
Durmaz, B1
Bagca, BG1
Cogulu, O1
Susluer, SY1
Alpay, A1
Aksoylar, S1
Gunduz, C1
Moriya, K1
Imamura, T2
Katayama, S1
Kaino, A1
Okamoto, K2
Yokoyama, N1
Uemura, S1
Kitazawa, H1
Sekimizu, M1
Hiramatsu, H1
Usami, I1
Ishida, H1
Hasegawa, D5
Hama, A1
Moriya-Saito, A2
Sato, A2
Sasahara, Y1
Suenobu, S1
Horibe, K3
Hara, J2
G, L1
Adamaki, M2
Hatziagapiou, K2
Geronikolou, SA1
Tsartsalis, AN1
Vlahopoulos, S3
Sbirkov, Y1
Vergov, B1
Dzharov, V1
Schenk, T1
Petrie, K1
Sarafian, V1
Nekoeian, S1
Ferdowsian, S1
Asgari, Y1
Azizi, Z1
Sawada, M1
Takachi, T1
Watanabe, K2
Tsuchiya, Y1
Nishimura, K1
Hotta, Y1
Sato, M1
Sumi, M1
Kitahara, M1
Shishido, T1
Kazumoto, H1
Uematsu, N1
Kirihara, T1
Sato, K1
Ueki, T1
Hiroshima, Y1
Shimizu, K1
Kobayashi, H2
Jabbar, N1
Mansoor, N1
Nadeem, K1
Maqsood MSc, S1
Butt, Z1
Ashraf, S1
Sai, S2
Esteves, C1
Kelly, V1
Sakaguchi, K2
McAndrew, R1
Chudleigh, S1
Spence, A1
Gibson, B5
Thomas, A1
Chapman, KE2
Sawaki, A1
Miyazaki, K1
Yamaguchi, M1
Takeuchi, T1
Kobayashi, K2
Imai, H1
Tawara, I1
Ono, R1
Nosaka, T1
Katayama, N1
Lambrou, GI2
Ganbarjeddi, S1
Azimi, A5
Zadi Heydarabad, M4
Hemmatzadeh, M1
Mohammadi, S1
Mousavi Ardehaie, R1
Zamani, M1
Baharaghdam, S1
Esmaeili, S1
Ghasemi, A2
Saburi, M1
Ogata, M2
Soga, Y1
Itani, K1
Kohno, K1
Nakayama, T1
Myint, HH1
Tandon, S1
Narula, G1
Prasad, M1
Subramanian, P1
Patkar, N1
Tembhare, P1
Gujral, S1
Banavali, S1
Matsushima, S1
Kobayashi, R1
Sano, H3
Hori, D1
Yanagi, M1
Kodama, K1
Suzuki, D1
Seetharam, S2
Thankamony, P2
Gopakumar, KG2
Nair, RA1
Jacob, PM1
Jagathnath Krishna, KM1
Rajeswari, B2
Nair, M2
Guruprasad, CS1
Prasanth, VR1
Sassen, SDT1
Mathôt, RAA1
Pieters, R35
de Haas, V1
Kaspers, GJL1
van den Bos, C1
Tissing, WJE1
Te Loo, DMWW1
Bierings, MB1
van der Sluis, IM2
Zwaan, CM2
Innes, AJ1
Mullish, BH1
Fernando, F1
Adams, G1
Marchesi, JR1
Apperley, JF1
Brannigan, E1
Davies, F1
Pavlů, J1
Jiang, J2
Yin, XY1
Song, XW1
Xie, D1
Xu, HJ1
Yang, J1
Sun, LR1
Rensen, N2
Gemke, RJ3
van Dalen, EC3
Rotteveel, J3
Kaspers, GJ14
Fujimaki, K2
Hattori, Y2
Nakajima, H1
Faizan, M1
Anwar, S1
Khan, S1
Nikasa, M1
Vatanmakanian, M1
Farshdousti Hagh, M1
Mochizuki, K2
Kobayashi, S3
Ohara, Y2
Ito, M4
Waragai, T2
Takahashi, N2
Ikeda, K2
Ohto, H1
Kikuta, A4
Chandar, R1
Appanraj, P1
Cs, G1
Khanzadeh, T1
Khorrami, A2
Jahanban Esfahlan, A1
Ghavipanjeh, S1
Gholipour Belverdi, M1
Darvishani Fikouhi, S1
Darbin, A1
Najafpour, M2
Hirabayashi, S1
Yamamoto, K2
Nishimura, A1
Hosoya, Y1
Shuo, T1
Kiyokawa, N3
Miura, M1
Manabe, A5
Mizia-Malarz, A1
Sobol-Milejska, G1
Talebi, M1
Bahar Aghdam, S1
Mohammadi, H1
Karimi Yonjali, S1
Asariha, M1
Chou, DTS1
Taylor, M1
Baker, M1
Studer, P1
Solomon, LB1
Aoki, T1
Urata, S1
Ishihara, D1
Umeno, T1
Kamimura, T1
Li, C1
Cai, X2
Chen, X1
Liang, Y2
Xia, Z1
Wang, H1
Gatineau-Sailliant, S1
Buchbinder, N1
Callat, MP1
Nelken, B1
Pautard, B1
Vannier, JP1
Schneider, P5
Esmer, O1
Karadag, R1
Soylu, E1
Oner, AF2
Burakgazi-Dalkilic, E1
Fichel, F1
Eschard, C1
Zachar, D1
Munzer, M4
Bernard, P1
Grange, F1
Hassan, IB1
Kristensen, J1
Alizadeh, H1
Bernsen, R1
Yan, J1
Jiang, N3
Huang, G1
Tay, JL1
Lin, B1
Bi, C1
Koh, GS3
Li, Z1
Tan, J1
Chung, TH1
Lu, Y1
Ariffin, H3
Kham, SK4
Yeoh, AE4
Chng, WJ1
Spijkers-Hagelstein, JA4
Pinhanços, SS1
Stam, RW4
Mei, YY1
Gao, C1
Cui, L1
Zhao, XX1
Zhao, W1
Li, WJ1
Wang, KL1
Zhang, RD1
Xie, J1
Shi, HW1
Wang, B1
Zhang, YH1
Ma, XL1
Zhou, X1
Wu, MY1
Li, ZG1
Hyakuna, N2
Shimomura, Y1
Watanabe, A3
Taga, T3
Matsushita, T2
Kogawa, K1
Kawakami, C1
Horikoshi, Y4
Iwai, T1
Okamoto, Y2
Tsurusawa, M4
Asami, K4
Ariës, IM2
Hansen, BR1
Koch, T1
van den Dungen, R1
Evans, WE7
den Boer, ML16
Wang, J2
Huang, XJ1
Jiang, B1
Jiang, Q1
Lu, XJ1
Xu, LP1
Liu, DH1
Chen, H1
Bao, L1
Lu, J1
Zhu, HH1
Jiang, H1
Pinhanços, SM1
Garrido Castro, P1
Domenech, C1
Suciu, S4
De Moerloose, B2
Mazingue, F3
Plat, G1
Ferster, A3
Uyttebroeck, A2
Sirvent, N2
Lutz, P3
Yakouben, K2
Röhrlich, P1
Plantaz, D3
Millot, F2
Philippet, P2
Dastugue, N1
Girard, S1
Cavé, H1
Benoit, Y3
Bertrandfor, Y1
Güneş, AM1
Oren, H1
Baytan, B1
Bengoa, SY1
Evim, MS1
Gözmen, S1
Tüfekçi, O1
Karapınar, TH1
Irken, G1
Koh, K4
Tomizawa, D1
Moriya Saito, A1
Watanabe, T2
Miyamura, T1
Hirayama, M1
Takahashi, Y1
Ogawa, A1
Kato, K1
Sugita, K4
Sato, T2
Deguchi, T2
Hayashi, Y4
Takita, J2
Takeshita, Y1
Mizutani, S1
Ishii, E4
Bindreither, D1
Ecker, S1
Gschirr, B1
Kofler, A1
Kofler, R1
Rainer, J1
Akaihata, M1
Hosoya, M1
Brady, V1
Thosani, S1
Zhou, S1
Bassett, R1
Busaidy, NL1
Lavis, V1
Nemes, K1
Csóka, M1
Nagy, N1
Márk, Á1
Váradi, Z1
Dankó, T1
Kovács, G2
Kopper, L1
Sebestyén, A1
van den Dungen, RE1
Koudijs, MJ1
Cuppen, E1
Voest, E1
Molenaar, JJ1
Caron, HN1
Pang, L1
Pan, J1
Wang, JR1
Chai, YH1
Zhao, WL1
Suzuki, R1
Kobayashi, C1
Sakai, A1
Fukushima, H1
Tagawa, M1
Satomi, K1
Nanmoku, T1
Sumazaki, R1
Fukushima, T4
Paugh, SW2
Bonten, EJ1
Savic, D1
Ramsey, LB1
Thierfelder, WE1
Gurung, P1
Malireddi, RK1
Actis, M1
Mayasundari, A1
Min, J1
Coss, DR1
Laudermilk, LT1
Panetta, JC2
McCorkle, JR1
Fan, Y1
Crews, KR1
Stocco, G1
Wilkinson, MR1
Ferreira, AM1
Cheng, C4
Yang, W4
Karol, SE1
Fernandez, CA1
Diouf, B1
Smith, C1
Hicks, JK1
Zanut, A1
Giordanengo, A1
Crona, D1
Bianchi, JJ1
Holmfeldt, L1
Mullighan, CG1
Jeha, S1
Dunwell, TL1
Latif, F1
Bhojwani, D1
Carroll, WL3
Pui, CH5
Myers, RM1
Guy, RK1
Kanneganti, TD1
Relling, MV4
Liu, L1
Qu, Q1
Jiao, W1
Zhang, Y1
Li, X1
Ding, C1
Wu, D2
Kim, DY2
Joo, YD2
Lim, SN2
Kim, SD1
Lee, JH6
Kim, DH1
Kim, K1
Jung, CW2
Kim, I2
Yoon, SS1
Park, S2
Ahn, JS1
Yang, DH2
Lee, JJ1
Lee, HS1
Kim, YS1
Mun, YC1
Kim, H2
Park, JH1
Moon, JH2
Sohn, SK2
Lee, SM2
Lee, WS2
Kim, KH1
Won, JH2
Hyun, MS2
Park, J1
Shin, HJ2
Chung, JS1
Lee, H1
Eom, HS2
Lee, GW2
Cho, YU1
Jang, S1
Park, CJ1
Chi, HS2
Lee, KH2
Yun, SC1
Ryoo, HM1
Bae, SH1
Kim, MK1
Kim, HJ1
Jang, DY1
Gordijn, MS2
Jones, CL1
Gearheart, CM1
Fosmire, S1
Delgado-Martin, C1
Evensen, NA1
Bride, K1
Waanders, AJ1
Pais, F1
Bhatla, T1
Bitterman, DS1
de Rijk, SR1
Bourgeois, W1
Dandekar, S1
Park, E1
Burleson, TM1
Madhusoodhan, PP1
Teachey, DT1
Raetz, EA1
Hermiston, ML1
Müschen, M1
Loh, ML1
Hunger, SP1
Zhang, J1
Garabedian, MJ1
Porter, CC1
Hossain, IT1
Moosajee, M1
Abou-Rayyah, Y1
Pavasovic, V1
Takata, H1
Ikebe, T1
Sasaki, H1
Miyazaki, Y1
Ohtsuka, E1
Saburi, Y1
Shirao, K1
Yano, M1
Asai, D1
Suenobu, SI1
Hashii, Y1
Kawasaki, H2
Hori, H1
Yumura-Yagi, K1
Hagh, MF1
Yousefi, B1
Rahnama, MA1
Heydarabad, MZ1
Hallajzadeh, J1
Ghahremani, A1
Campana, D2
Ohara, A4
Saito, T5
Kikuchi, A3
Takahashi, H4
Ikuta, K5
Hanada, R7
Tsuchida, M5
Lönnerholm, G2
Thörn, I2
Sundström, C4
Frost, BM2
Abrahamsson, J1
Behrendtz, M1
Heldrup, J1
Jacobsson, S1
Li, A1
Olofsson, T1
Porwit, A2
Söderhäll, S2
Larsson, R3
Forestier, E2
Bajel, A1
George, B1
Mathews, V1
Viswabandya, A1
Kavitha, ML1
Srivastava, A1
Chandy, M1
Figliolia, SL1
Oliveira, DT2
Pereira, MC1
Lauris, JR1
Maurício, AR1
Mello de Andrea, ML1
Nishikawa, T1
Kawakami, K3
Kumamoto, T1
Tonooka, S1
Abe, A1
Hayasaka, K1
Kawano, Y1
Papadopoulos, A1
Ntaios, G1
Kaiafa, G1
Girtovitis, F1
Saouli, Z1
Kontoninas, Z1
Diamantidis, MD1
Savopoulos, C1
Hatzitolios, A1
Hulleman, E3
Kazemier, KM4
Holleman, A4
VanderWeele, DJ1
Rudin, CM1
Broekhuis, MJ3
Koharazawa, H2
Kanamori, H1
Sakai, R3
Hashimoto, C1
Takemura, S1
Hattori, M1
Taguchi, J2
Tomita, N4
Fujita, H2
Fujisawa, S3
Harano, H1
Ogawa, K2
Motomura, S1
Maruta, A3
Ishigatsubo, Y2
Pottier, N1
Assem, M1
Pei, D2
Cheok, MH3
Goto, H2
Naruto, T1
Tanoshima, R1
Kato, H1
Yokosuka, T1
Yanagimachi, M2
Fujii, H1
Yokota, S3
Komine, H1
Bonney, D1
Razali, H1
Turner, A1
Will, A1
Janiszewska, H1
Styczynski, J6
Kolodziej, B2
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Gushi, K1
Kawakami, T1
Sekine, I1
Izichi, O1
Okano, A1
Shimazaki, C1
Ochiai, N1
Hatsuse, M1
Takahashi, R1
Ashihara, E1
Inaba, T1
Fujita, N1
Noda, Y1
Nakagawa, M1
de Vries, E1
Peters, GJ1
Creutzig, U1
Chen, YC1
Ho, CL1
Kao, WY1
Hwang, JM1
Sheu, LF1
Chao, TY1
Papadopoulou, AL1
Moschovi, M1
Botsonis, A1
Tsangaris, GT1
Ramakers-van Woerden, NL1
Hoelzer, D1
Slater, RM1
Loonen, AH3
Ossenkoppele, GJ1
Vyas, V1
Shah, SA1
Patel, KM1
Parekh, BB1
Nath, SV1
Hussain, BM1
Kyo, T1
Naito, K1
Sao, H1
Takahashi, M1
Miyawaki, S1
Ohtake, S1
Yagasaki, F1
Murakami, H1
Asou, N1
Ino, T1
Okamoto, T1
Usui, N1
Shinagawa, K1
Morii, T1
Mizuta, S1
Akiyama, H1
Nakamura, Y1
Sweetenham, JW1
Mead, GM1
Whitehouse, JM1
Reid, MM1
Saito, H2
Damonte, JC1
Dufour, P1
Maloisel, F1
Liu, KL1
Ortiz, S1
Bergerat, JP1
Oberling, F1
Imeson, J1
Cotterill, S1
Gerrard, M1
Pinkerton, CR1
Isaev, VG1
Savchenko, VG1
Kucher, RA1
Abakumov, EM1
Parovichnikova, EN1
Jain, AK1
Gupta, RC1
Bhardwaj, B1
Leelani, N1
Sasaki, A1
Tsukaguchi, M1
Musch, E1
Malek, M1
Peter-Katalinic, J1
Egge, H1
Rink, H1
Lathan, B1
Riedel, E1
Advani, SH1
Iyer, RS1
Pai, SK1
Saikia, TK1
Nair, CN1
Kurkure, PA1
Nadkarni, KS1
Pai, VR1
Rohatiner, AZ3
Carter, M1
MacCallum, P1
Amess, J3
Maruyama, H1
Kawano, K1
Uno, H1
Matsuoka, H1
Yamashita, R1
Tamaki, N1
Ishizaki, J1
Maeda, K1
Tsuda, K1
Kanamaru, A1
Kakishita, E1
Nagai, K1
Horiuchi, A1
Kitani, T1
Yasunaga, K1
Kawagoe, H1
Tatsumi, N1
Kageyama, T1
Takai, K1
Sanada, M1
Takeda, T3
Utsumi, J1
Ohta, S1
Philips, GK1
Crowell, EB1
Mani, A1
Volkova, MA1
Perilov, AA1
Kaletin, GI1
Tupitsyn, NN1
Frenkel', MA1
Fleĭshman, EV1
Komiyama, A1
Nielsen, SH1
Hasselbalch, HC1
Birgens, HS1
Culbert, SJ1
Shuster, JJ1
Land, VJ1
Wharam, MD1
Thomas, PR1
Nitschke, R1
Pinkel, D1
Vietti, TJ1
Umeda, M1
Shikoshi, K1
Anno, S1
Su, CY1
Shirai, T1
Màrky, I1
Mellander, L1
Lannering, B1
Albertsson-Wikland, K1
Pinkel', D1
Mendeleev, IM1
Kovrigina, TI1
Polezhaev, IuN1
Wakiguchi, H1
Fujieda, M1
Hisakawa, H1
Kubota, H1
Matsumoto, K1
Kurashige, T1
Barnett, MJ2
Gregory, W2
Lim, J2
Oza, A2
Horton, M2
Henze, G1
Fengler, R1
Ritter, J1
Schunior, A2
Zengel, AE1
Mullenix, PJ2
Tarbell, NJ2
Howes, A2
Tassinari, MS2
Kernan, WJ1
Waber, DP1
Tonouchi, T1
Ueda, R1
Kondo, M1
Hayashi, S1
Nagafuchi, S1
Ohtsuka, T1
Shibuya, T1
Harada, M1
Niho, Y1
Balázs, M1
Kovács, I1
Karmazsin, L1
Dirven, MW1
Heyenbrok, MW1
Liu, K1
Lobo, AJ1
Foster, PN1
Burke, DA1
Johnston, D1
Axon, AT1
Digilio, G1
Multari, G1
Werner, B1
Ballati, G1
Lemmo, M1
Sirignano, A1
Iacobini, M1
Roggini, M1
Cozzi, F1
Tanabe, N1
Nakura, E1
Uzuka, Y1
Komatsu, M1
Ito, T1
Toyota, T1
Takahashi, I1
Inagaki, N1
Nakada, H1
Hayashi, N1
Sekito, N1
Nonaka, K1
Takeuchi, M1
Osada, K1
Matuzaki, T1
Fujieda, H1
Hojo, H1
Baba, Y1
Choonara, I1
Wheeldon, J1
Rayner, P1
Blackburn, M1
Lewis, I1
Cheng, PN1
Tso, SC1
Chan, TK1
Todd, D1
Lawton, JW1
Ho, FC1
O'Connor, NT1
Hoffbrand, AV1
van Eys, J1
Berry, D1
Crist, W1
Doering, E1
Fernbach, D1
Pullen, J1
Shuster, J1
Wharam, M1
Yanai, M1
Yatabe, M1
Utumi, J1
Hiyosi, Y1
Tanaka, K1
Yaoi, K1
Moëll, C1
Garwicz, S1
Westgren, U1
Wiebe, T1
Gustafsson, G1
Kreuger, A1
Nakadate, H1
Hatayama, Y1
Smedmyr, B1
Killander, A1
Simonsson, B1
Javier, G1
Olivé, T1
Mitani, K1
Kobayashi, Y1
Kawamura, Y1
Yuo, A1
Ishikawa, F1
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Ozawa, K1
Kitamura, K1
Shabalin, VN1
Serova, LD1
Rozanova, OE1

Clinical Trials (15)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Value of Dexamethasone Versus Prednisolone During Induction and Maintenance Therapy of Prolonged Versus Conventional Duration of L-Asparaginase Therapy During Consolidation and Late Intensification, and of Corticosteroid + VCR Pulses During Maintenanc[NCT00003728]Phase 31,500 participants (Anticipated)Interventional1998-12-31Active, not recruiting
Total XV - Total Therapy Study XV for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia[NCT00137111]Phase 3501 participants (Actual)Interventional2000-07-08Completed
Tasigna® (Nilotinib) Plus Multi-Agent Chemotherapy for Newly-Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia[NCT00844298]Phase 291 participants (Actual)Interventional2009-01-31Completed
Ponatinib Plus Reduced-intensity Chemotherapy in the First-line Treatment of Adult Patients With Ph-positive Acute Lymphoblastic Leukemia[NCT04554459]Phase 232 participants (Anticipated)Interventional2021-02-16Active, not recruiting
Treatment Protocol for Newky Diagnosed Adult Ph-Chromosome Positive (BCR::ABL1) Acute Lymphoblastic Leukemia (LALPh2022)[NCT06175702]150 participants (Anticipated)Observational2023-12-25Not yet recruiting
A RANDOMIZED PHASE III TRIAL COMPARING DEXAMETHASONE WITH PREDNISONE IN INDUCTION TREATMENT AND BONE MARROW TRANSPLANTATION WITH INTENSIVE MAINTENANCE TREATMENT IN ADOLESCENT AND ADULT ACUTE LYMPHOBLASTIC LEUKEMIA (ALL-4)[NCT00002700]Phase 3392 participants (Anticipated)Interventional1995-08-31Completed
Induction Intensification in Infant ALL: A Children's Oncology Group Study[NCT00002756]Phase 2221 participants (Actual)Interventional1996-06-30Completed
Medical Research Council Working Party on Leukaemia in Children UK National Lymphoblastic Leukaemia (ALL) Trial[NCT00003437]Phase 31,800 participants (Anticipated)Interventional1997-01-31Active, not recruiting
Study of Pharmacokinetic Variability of Glucocorticoids in Children[NCT02252237]146 participants (Actual)Observational2014-12-03Completed
Measurement of Body Composition by Air Displacement Plethysmography in Pediatric Intestinal Failure Patients[NCT02561819]25 participants (Anticipated)Observational2015-11-30Completed
Phase III Randomized Trial of Autologous and Allogeneic Stem Cell Transplantation Versus Intensive Conventional Chemotherapy in Acute Lymphoblastic Leukemia in First Remission[NCT00002514]Phase 31,929 participants (Actual)Interventional1993-05-07Completed
Multicenter, Prospective, Open Label Trial, Uncontrolled to Determine the Efficacy and Safety of Depocyt ® for the Treatment of CNS Relapse in Adult Patients With Lymphoblastic Leucemia or Very Aggressive Lymphoma[NCT00388531]Phase 210 participants (Anticipated)Interventional2006-03-31Completed
PETHEMA LAL-RI/96: Treatment for Patients With Standard Risk Acute Lymphoblastic Leukemia[NCT00494897]Phase 4374 participants (Actual)Interventional1996-06-30Completed
Clinical-microbiological Study of Oral Health Condition and Quality of Life of Children/Adolescent With Acute Lymphoid Leukemia and Acute Myeloid[NCT04968860]3 participants (Anticipated)Observational [Patient Registry]2019-09-01Recruiting
"Geriatric Assessment Adapted Therapy for Ph- ALL Elderly Patients. GIMEMA Protocol LAL1104. EudraCT Code 2005-002156-17"[NCT00475280]Phase 2102 participants (Actual)Interventional2007-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Circulating Leukemia Cells in Peripheral Blood Change From Prior to the Methotrexate Infusion to Three Days After Between Two Arms (4 Hours vs. 24 Hours)

"White blood cell (leukocytes) counts in peripheral blood by Complete Blood Count~Measurement: Percentage change of leukemia cells from baseline" (NCT00137111)
Timeframe: Immediately before the methotrexate infusion and three days after subsequent infusion

InterventionPercent change (Mean)
4 hr-44
24 hr-50

Continuous Complete Remission Since Week 56 Therapy.

CCR was measured from end of week 56 therapy to the date of first treatment failure of any kind (relapse, death, lineage switch, or second malignancy) or to the last date of follow-up. Measurement was determined by Kaplan-Meyer estimate. (NCT00137111)
Timeframe: Median follow up time (range) 4.5 (1 to 7.8) years

InterventionPercentage of participants (Number)
Patients With High Risk of CNS Relapse92.2

Mean Difference of Active Methotrexate Polyglutamates (MTXPG) in Leukemia Cells Between Two Arms (4 Hours vs. 24 Hours).

Children were randomly assigned to receive initial single-agent treatment with HDMTX (1g/m^2) as either a 24-hour infusion or a 4-hour infusion and the outcome measure was the accumulation of MTXPG in leukemia cells. (NCT00137111)
Timeframe: 42 hours after start of high dose methotrexate infusion (HDMTX)

Interventionpmol/1,000,000,000 cells (Mean)
4 hr1688
24 hr2521

Overall Event-free Survival (EFS)

EFS was measured from the start of on-study to the date of first treatment failure of any kind (relapse, death, lineage switch, or second malignancy) or to the last date of follow-up. Failure to enter remission was considered an event at time zero. Measurement was determined by Kaplan-Meyer estimate. (NCT00137111)
Timeframe: Median follow-up time (range) 5.6 (1.3 to 8.9) years

InterventionPercentage of Participants (Number)
Total Therapy87.3

Median Difference in CASP1 Gene Expression in Primary Leukemia Cells of Patients in Glucocorticoid-resistant Cells vs Glucocorticoid-sensitive Cells

Prednisolone sensitivity was measured in primary leukemia cells from bone marrow collected at diagnosis. Expression of CASP1 was determined by HG-U133A microarray. Values given are gene expression values, and the unit is arbitrary units (AU) defined as scaled fluorescence measured on microarray. (NCT00137111)
Timeframe: Pre-treatment

Interventionarbitrary units (Median)
Prednisolone-sensitive cellsPrednisolone-resistant cells
Total Therapy341.3447.9

Median Difference in NLRP3 Gene Expression in Primary Leukemia Cells of Patients in Glucocorticoid-resistant Cells vs. Glucocorticoid-sensitive Cells

Prednisolone sensitivity was measured in primary leukemia cells from bone marrow collected at diagnosis. Expression of NLRP3 was determined by HG-U133A microarray. Values given are gene expression values, and the unit is arbitrary units (AU) defined as scaled fluorescence measured on microarray. (NCT00137111)
Timeframe: Pre-treatment

Interventionarbitrary units (Median)
Prednisolone-sensitive cellsPrednisolone-resistant cells
Total Therapy41.2110.7

Minimal Residual Disease (MRD)

Detection of MRD at end of induction where positive MRD was defined as one or more leukemic cell per 10,000 mononuclear bone-marrow cells (>=0.01%). (NCT00137111)
Timeframe: End of Induction (Day 46 MRD measurement)

Interventionparticipants (Number)
Negative <0.01%Positive >= 0.01%
Total Therapy390102

Proportion of Patients Achieving Hematologic and Molecular Complete Remission (CR) After Induction Therapy

approximate time: at the recovery of cytopenia (NCT00844298)
Timeframe: 1 month

Interventionpercentage of analyzable subjects (Number)
Nilotinib+mVPD91

Reviews

23 reviews available for prednisolone and Acute Lymphoid Leukemia

ArticleYear
Myocarditis with Advanced Atrioventricular Block after Allogeneic Stem Cell Transplantation: A Case Report and Literature Review.
    Internal medicine (Tokyo, Japan), 2020, Jan-01, Volume: 59, Issue:1

    Topics: Atrioventricular Block; Cord Blood Stem Cell Transplantation; Female; Glucocorticoids; Graft vs Host

2020
Gene Expression and Resistance to Glucocorticoid-Induced Apoptosis in Acute Lymphoblastic Leukemia: A Brief Review and Update.
    Current drug research reviews, 2020, Volume: 12, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Drug Resistance, Neoplasm; Gene Expression Regulation, Ne

2020
Hypothalamic-pituitary-adrenal (HPA) axis suppression after treatment with glucocorticoid therapy for childhood acute lymphoblastic leukaemia.
    The Cochrane database of systematic reviews, 2017, 11-06, Volume: 11

    Topics: Adrenal Insufficiency; Antineoplastic Agents, Hormonal; Child; Cohort Studies; Dexamethasone; Flucon

2017
Hypothalamic-pituitary-adrenal (HPA) axis suppression after treatment with glucocorticoid therapy for childhood acute lymphoblastic leukaemia.
    The Cochrane database of systematic reviews, 2015, Aug-17, Issue:8

    Topics: Adrenal Insufficiency; Antineoplastic Agents, Hormonal; Child; Cohort Studies; Dexamethasone; Glucoc

2015
Minimal residual disease-guided therapy in childhood acute lymphoblastic leukemia.
    Blood, 2017, 04-06, Volume: 129, Issue:14

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child, Preschool; Cyclophosphamide; Da

2017
Hypothalamic-pituitary-adrenal (HPA) axis suppression after treatment with glucocorticoid therapy for childhood acute lymphoblastic leukaemia.
    The Cochrane database of systematic reviews, 2012, May-16, Issue:5

    Topics: Adrenal Insufficiency; Antineoplastic Agents, Hormonal; Child; Cohort Studies; Dexamethasone; Glucoc

2012
AML1 amplification in a child with acute lymphoblastic leukemia.
    Cancer genetics and cytogenetics, 2003, Jan-01, Volume: 140, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Chromosome Aberrations; Chromos

2003
[Acute myeloid leukemia originating from the same leukemia clone after the complete remission of acute lymphoid leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2003, Volume: 44, Issue:9

    Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Clone Cells; Doxorubicin; Fema

2003
[Results and suggestion from comparing between world excellent protocols of childhood acute lymphoblastic leukemia].
    Zhonghua er ke za zhi = Chinese journal of pediatrics, 2003, Volume: 41, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Clinical Trials as Topic; Cyclophosphamide; D

2003
Compliance with oral chemotherapy in childhood lymphoblastic leukaemia.
    Cancer treatment reviews, 1995, Volume: 21, Issue:2

    Topics: Administration, Oral; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Attitude to Health

1995
[Progress of chemotherapy in adult acute leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1995, Volume: 22, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Daun

1995
Therapy for Philadelphia chromosome-positive acute lymphoblastic leukemia: possible use of interferon on the basis of some novel concepts.
    Leukemia & lymphoma, 1993, Volume: 9, Issue:1-2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined M

1993
[Hand-mirror cells acute lymphoblastic leukemia (L3)].
    Rinsho byori. The Japanese journal of clinical pathology, 1995, Volume: 43, Issue:11

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Bone Marrow Cells; Doxorub

1995
[Chemotherapy of relapsed AML and ALL].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1996, Volume: 37, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cytarabine; Etoposide; Granulocyte Col

1996
[Polycythemia vera progressing to acute lymphoblastic leukemia after 13 years].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1996, Volume: 37, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Middle Age

1996
[Recent advances on the treatment of acute childhood leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Daunorubicin; Disease-Free Surviv

1997
Apoptosis and acute lymphocytic leukemia in children.
    Annals of the New York Academy of Sciences, 1997, Sep-17, Volume: 824

    Topics: Adolescent; Apoptosis; Child; Child, Preschool; Female; Humans; Male; Precursor Cell Lymphoblastic L

1997
[Relapse of acute lymphoblastic leukemia as a retro-orbital mass].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1999, Volume: 40, Issue:11

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Methotrexate; Orbital Ne

1999
Long-term outcome of treatment with protocols AL841, AL851, and ALHR88 in children with acute lymphoblastic leukemia: results obtained by the Kyushu-Yamaguchi Children's Cancer Study Group.
    International journal of hematology, 2001, Volume: 73, Issue:3

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Body Height; Body Weight;

2001
Subcutaneous infection with Mycobacterium fortuitum after allogeneic bone marrow transplantation.
    Bone marrow transplantation, 2001, Volume: 28, Issue:7

    Topics: Adult; Bone Marrow Transplantation; Clarithromycin; Combined Modality Therapy; Cyclosporine; Debride

2001
Low relapse rate in children with acute lymphoblastic leukemia after risk-directed therapy.
    Journal of pediatric hematology/oncology, 2001, Volume: 23, Issue:9

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow; Bone Marrow T

2001
Hypereosinophilic syndrome evolving to acute lymphoblastic leukemia.
    International journal of hematology, 1991, Volume: 54, Issue:3

    Topics: Adult; Blood Proteins; Endocardium; Endomyocardial Fibrosis; Eosinophil Granule Proteins; Eosinophil

1991
[Transient hypofibrinogenemia induced by prednisolone in a case of acute lymphoblastic leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1989, Volume: 30, Issue:7

    Topics: Afibrinogenemia; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Fem

1989

Trials

70 trials available for prednisolone and Acute Lymphoid Leukemia

ArticleYear
Evaluation of the pharmacokinetics of prednisolone in paediatric patients with acute lymphoblastic leukaemia treated according to Dutch Childhood Oncology Group protocols and its relation to treatment response.
    British journal of haematology, 2021, Volume: 194, Issue:2

    Topics: Adolescent; Antineoplastic Agents, Hormonal; Area Under Curve; Child; Child, Preschool; Female; Huma

2021
Dexamethasone (6 mg/m2/day) and prednisolone (60 mg/m2/day) were equally effective as induction therapy for childhood acute lymphoblastic leukemia in the EORTC CLG 58951 randomized trial.
    Haematologica, 2014, Volume: 99, Issue:7

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Dexamethasone;

2014
Nilotinib combined with multiagent chemotherapy for newly diagnosed Philadelphia-positive acute lymphoblastic leukemia.
    Blood, 2015, Aug-06, Volume: 126, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Daunorubicin; Drug Administ

2015
Nilotinib combined with multiagent chemotherapy for newly diagnosed Philadelphia-positive acute lymphoblastic leukemia.
    Blood, 2015, Aug-06, Volume: 126, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Daunorubicin; Drug Administ

2015
Nilotinib combined with multiagent chemotherapy for newly diagnosed Philadelphia-positive acute lymphoblastic leukemia.
    Blood, 2015, Aug-06, Volume: 126, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Daunorubicin; Drug Administ

2015
Nilotinib combined with multiagent chemotherapy for newly diagnosed Philadelphia-positive acute lymphoblastic leukemia.
    Blood, 2015, Aug-06, Volume: 126, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Daunorubicin; Drug Administ

2015
Nilotinib combined with multiagent chemotherapy for newly diagnosed Philadelphia-positive acute lymphoblastic leukemia.
    Blood, 2015, Aug-06, Volume: 126, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Daunorubicin; Drug Administ

2015
Nilotinib combined with multiagent chemotherapy for newly diagnosed Philadelphia-positive acute lymphoblastic leukemia.
    Blood, 2015, Aug-06, Volume: 126, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Daunorubicin; Drug Administ

2015
Nilotinib combined with multiagent chemotherapy for newly diagnosed Philadelphia-positive acute lymphoblastic leukemia.
    Blood, 2015, Aug-06, Volume: 126, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Daunorubicin; Drug Administ

2015
Nilotinib combined with multiagent chemotherapy for newly diagnosed Philadelphia-positive acute lymphoblastic leukemia.
    Blood, 2015, Aug-06, Volume: 126, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Daunorubicin; Drug Administ

2015
Nilotinib combined with multiagent chemotherapy for newly diagnosed Philadelphia-positive acute lymphoblastic leukemia.
    Blood, 2015, Aug-06, Volume: 126, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Daunorubicin; Drug Administ

2015
Long-term follow-up of imatinib plus combination chemotherapy in patients with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia.
    American journal of hematology, 2015, Volume: 90, Issue:11

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; D

2015
MAPK signaling cascades mediate distinct glucocorticoid resistance mechanisms in pediatric leukemia.
    Blood, 2015, Nov-05, Volume: 126, Issue:19

    Topics: Adolescent; Animals; Cell Line, Tumor; Child; Child, Preschool; Drug Resistance, Neoplasm; Female; G

2015
Long-term outcome of L86 and L97 protocols for adult acute lymphoblastic leukemia.
    Leukemia & lymphoma, 2008, Volume: 49, Issue:11

    Topics: Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Fem

2008
Risk of relapse of childhood acute lymphoblastic leukemia is predicted by flow cytometric measurement of residual disease on day 15 bone marrow.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Nov-01, Volume: 27, Issue:31

    Topics: Adrenal Cortex Hormones; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Dexamethasone;

2009
Dexamethasone compared to prednisolone for adults with acute lymphoblastic leukemia or lymphoblastic lymphoma: final results of the ALL-4 randomized, phase III trial of the EORTC Leukemia Group.
    Haematologica, 2010, Volume: 95, Issue:9

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Proto

2010
Improved outcome with pulses of vincristine and corticosteroids in continuation therapy of children with average risk acute lymphoblastic leukemia (ALL) and lymphoblastic non-Hodgkin lymphoma (NHL): report of the EORTC randomized phase 3 trial 58951.
    Blood, 2010, Jul-08, Volume: 116, Issue:1

    Topics: Adrenal Cortex Hormones; Antineoplastic Combined Chemotherapy Protocols; Chemical and Drug Induced L

2010
Which steroids should we choose for the treatment of adult acute lymphoblastic leukemia?
    American journal of hematology, 2010, Volume: 85, Issue:10

    Topics: Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Daunorubicin; Dexa

2010
BIM is a prognostic biomarker for early prednisolone response in pediatric acute lymphoblastic leukemia.
    Experimental hematology, 2011, Volume: 39, Issue:3

    Topics: Antineoplastic Agents, Hormonal; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Bi

2011
The utility of performing the initial lumbar puncture on day 8 in remission induction therapy for childhood acute lymphoblastic leukemia: TCCSG L99-15 study.
    Pediatric blood & cancer, 2012, Volume: 58, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Case-Control Studies; Central Nervous Sy

2012
Modifications to induction therapy decrease risk of early death in infants with acute lymphoblastic leukemia treated on Children's Oncology Group P9407.
    Pediatric blood & cancer, 2012, Volume: 59, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Daunorubicin; Dexamethasone; Disease-Free Survival;

2012
Evaluation of adrenal reserve in children with acute lymphocytic leukemia treated with prednisone or dexamethasone.
    Hormone research in paediatrics, 2012, Volume: 78, Issue:2

    Topics: Adolescent; Adrenal Glands; Adrenocorticotropic Hormone; Antineoplastic Agents, Hormonal; Child; Chi

2012
Short-term effects on linear growth and bone turnover in children randomized to receive prednisolone or dexamethasone.
    Clinical endocrinology, 2002, Volume: 57, Issue:2

    Topics: Adolescent; Alkaline Phosphatase; Amino Acids; Biomarkers; Body Weight; Bone and Bones; Bone Remodel

2002
Benefit of high-dose methylprednisolone in comparison with conventional-dose prednisolone during remission induction therapy in childhood acute lymphoblastic leukemia for long-term follow-up.
    Leukemia, 2003, Volume: 17, Issue:2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Dose-Response R

2003
Population pharmacokinetics of prednisolone in children with acute lymphoblastic leukemia.
    Cancer chemotherapy and pharmacology, 2003, Volume: 51, Issue:6

    Topics: Administration, Oral; Adolescent; Algorithms; Anti-Inflammatory Agents; Biological Availability; Blo

2003
Short-term effects of prednisolone and dexamethasone on circulating concentrations of leptin and sex hormone-binding globulin in children being treated for acute lymphoblastic leukaemia.
    Clinical endocrinology, 2003, Volume: 58, Issue:6

    Topics: Adolescent; Body Mass Index; Child; Child, Preschool; Dexamethasone; Female; Glucocorticoids; Humans

2003
A randomized trial of induction therapy (daunorubicin, vincristine, prednisone versus daunorubicin, vincristine, prednisone, cytarabine and 6-thioguanine) in adult acute lymphoblastic leukemia with long-term follow-up: an Eastern Cooperative Oncology Grou
    Leukemia & lymphoma, 2003, Volume: 44, Issue:9

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabin

2003
Suppression of adrenal function in children with acute lymphoblastic leukemia following induction therapy with corticosteroid and other cytotoxic agents.
    The Journal of pediatrics, 2004, Volume: 144, Issue:6

    Topics: Adolescent; Adrenal Insufficiency; Adrenocorticotropic Hormone; Antineoplastic Agents, Hormonal; Chi

2004
Early response to induction is predictive of survival in childhood Philadelphia chromosome positive acute lymphoblastic leukaemia: results of the Medical Research Council ALL 97 trial.
    British journal of haematology, 2005, Volume: 129, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Chil

2005
Benefit of dexamethasone compared with prednisolone for childhood acute lymphoblastic leukaemia: results of the UK Medical Research Council ALL97 randomized trial.
    British journal of haematology, 2005, Volume: 129, Issue:6

    Topics: Adolescent; Age Factors; Central Nervous System; Child; Child, Preschool; Dexamethasone; Disease-Fre

2005
No advantage of dexamethasone over prednisolone for the outcome of standard- and intermediate-risk childhood acute lymphoblastic leukemia in the Tokyo Children's Cancer Study Group L95-14 protocol.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Sep-20, Volume: 23, Issue:27

    Topics: Child; Child, Preschool; Dexamethasone; Dose-Response Relationship, Drug; Drug Administration Schedu

2005
Bone mineral density and serum bone turnover markers in survivors of childhood acute lymphoblastic leukemia: comparison of megadose methylprednisolone and conventional-dose prednisolone treatments.
    American journal of hematology, 2005, Volume: 80, Issue:2

    Topics: Adolescent; Adult; Biomarkers; Bone Density; Bone Remodeling; Child; Cross-Sectional Studies; Dose-R

2005
Genomewide identification of prednisolone-responsive genes in acute lymphoblastic leukemia cells.
    Blood, 2007, May-01, Volume: 109, Issue:9

    Topics: Antineoplastic Agents, Hormonal; Child; Child, Preschool; Drug Resistance, Neoplasm; Female; Gene Ex

2007
Evaluation of renal function in Turkish children receiving BFM-95 therapy for acute lymphoblastic leukemia.
    Pediatric hematology and oncology, 2007, Volume: 24, Issue:4

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child

2007
High incidence of avascular necrosis in adolescents with acute lymphoblastic leukaemia: a UKALL XII analysis.
    Leukemia, 2008, Volume: 22, Issue:2

    Topics: Actuarial Analysis; Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols;

2008
Glucocorticoids in the treatment of children with acute lymphoblastic leukemia and hodgkin's disease: a pilot study on the adverse psychological reactions and possible associations with neurobiological, endocrine, and genetic markers.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Dec-01, Volume: 13, Issue:23

    Topics: Adolescent; Cell Death; Child; Child Behavior; Child, Preschool; Dexamethasone; Dose-Response Relati

2007
Intensive therapy for adult acute lymphoblastic leukemia: preliminary results of the idarubicin/vincristine/L-asparaginase/prednisolone regimen.
    Seminars in oncology, 1993, Volume: 20, Issue:6 Suppl 8

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow T

1993
Aggressive lymphomas with renal involvement: a study of 48 patients treated with the LNH-84 and LNH-87 regimens. Groupe d'Etude des Lymphomes de l'Adulte.
    British journal of cancer, 1994, Volume: 70, Issue:1

    Topics: Actuarial Analysis; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Ch

1994
Outcome of treatment in adult acute lymphoblastic leukaemia in an Asian population: comparison with previous multicentre German study.
    Leukemia, 1995, Volume: 9, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asia; Asparaginase; Cytarab

1995
[Treatment for elderly patients with acute non-lymphocytic leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1995, Volume: 36, Issue:2

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Da

1995
High efficacy of the German multicenter ALL (GMALL) protocol for treatment of adult acute lymphoblastic leukemia (ALL)--a single-institution study.
    Annals of hematology, 1994, Volume: 69, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Austria;

1994
Adult acute lymphoblastic leukemia: results of an aggressive regimen in India.
    Leukemia & lymphoma, 1994, Volume: 14, Issue:3-4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Combined Modality Therapy; Cran

1994
Treatment of childhood acute lymphoblastic leukemia with protocol TCL-842 in Taiwan: the Taiwan Children's Cancer Study Group.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 1993, Volume: 92, Issue:5

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; C

1993
[A late phase II study of idarubicin hydrochloride in adult patients with acute lymphocytic leukemia. Idarubicin Study Group].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:13

    Topics: Adolescent; Adult; Aged; Electrocardiography; Female; Humans; Idarubicin; Male; Middle Aged; Precurs

1993
Results of Medical Research Council trial UKALL IX in acute lymphoblastic leukaemia in adults: report from the Medical Research Council Working Party on Adult Leukaemia.
    British journal of haematology, 1993, Volume: 85, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase;

1993
Results of Medical Research Council trial UKALL IX in acute lymphoblastic leukaemia in adults: report from the Medical Research Council Working Party on Adult Leukaemia.
    British journal of haematology, 1993, Volume: 85, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase;

1993
Results of Medical Research Council trial UKALL IX in acute lymphoblastic leukaemia in adults: report from the Medical Research Council Working Party on Adult Leukaemia.
    British journal of haematology, 1993, Volume: 85, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase;

1993
Results of Medical Research Council trial UKALL IX in acute lymphoblastic leukaemia in adults: report from the Medical Research Council Working Party on Adult Leukaemia.
    British journal of haematology, 1993, Volume: 85, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase;

1993
Nation-wide randomized comparative study of doxorubicin, vincristine and prednisolone combination therapy with and without L-asparaginase for adult acute lymphoblastic leukemia.
    Cancer chemotherapy and pharmacology, 1994, Volume: 33, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Chi-Square Distribu

1994
[Results of the CCLSG high risk ALL 874 protocol in childhood acute lymphoblastic leukemia. Children's Cancer and Leukemia Study Group].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1993, Volume: 34, Issue:2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; C

1993
A randomized phase-III study of the efficacy of granulocyte colony-stimulating factor in children with high-risk acute lymphoblastic leukemia. Berlin-Frankfurt-Münster Study Group.
    Blood, 1996, Apr-15, Volume: 87, Issue:8

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; C

1996
Relationship between minimal residual disease and outcome in adult acute lymphoblastic leukemia.
    Blood, 1996, Jun-15, Volume: 87, Issue:12

    Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase;

1996
Age-adapted moderate-dose induction and flexible outpatient postremission therapy for elderly patients with acute lymphoblastic leukemia.
    Leukemia & lymphoma, 1996, Volume: 22, Issue:3-4

    Topics: Aged; Aging; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Dose-Response Relationshi

1996
Granulocyte colony-stimulating factor (G-CSF, filgrastim) after or during an intensive remission induction therapy for adult acute lymphoblastic leukaemia: effects, role of patient pretreatment characteristics, and costs.
    Leukemia & lymphoma, 1997, Volume: 26, Issue:1-2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cost-Benefit Analys

1997
Clinical value of glycated hemoglobin and fructosamine in the long-term glycemic control of children with acute lymphoblastic leukemia.
    Acta paediatrica Japonica : Overseas edition, 1998, Volume: 40, Issue:1

    Topics: Adolescent; Blood Glucose; Child; Child, Preschool; Female; Fructosamine; Glucocorticoids; Glycated

1998
Improved survival with early intensification: combined results from the Medical Research Council childhood ALL randomised trials, UKALL X and UKALL XI. Medical Research Council Working Party on Childhood Leukaemia.
    Leukemia, 1998, Volume: 12, Issue:7

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; C

1998
A comparison of the effect of high-dose methylprednisolone with conventional-dose prednisolone in acute lymphoblastic leukemia patients with randomization.
    Leukemia research, 1998, Volume: 22, Issue:6

    Topics: Adolescent; Age Factors; Antineoplastic Agents; Child; Child, Preschool; Disease-Free Survival; Dose

1998
Analysis of the immunophenotype of children treated on the Medical Research Council United Kingdom Acute Lymphoblastic Leukaemia Trial XI (MRC UKALLXI). Medical Research Council Childhood Leukaemia Working Party.
    Leukemia, 1998, Volume: 12, Issue:8

    Topics: Adolescent; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antineoplastic Combined Chemoth

1998
[Studies of childhood non-Hodgkin's lymphoma--treatment results with the CCLSG NHL 960 protocol. Children's Cancer and Leukemia Study Group (CCLSG)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1998, Volume: 39, Issue:11

    Topics: Adolescent; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkyla

1998
[Pilot late phase II study of KRN8602 (MX2), a novel anthracycline derivative, for acute leukemia--a dose finding study in combination].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:1

    Topics: Adult; Aged; Anorexia; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols;

1999
Induction-consolidation with an idarubicin-containing regimen, unpurged marrow autograft, and post-graft chemotherapy in adult acute lymphoblastic leukaemia.
    British journal of haematology, 1999, Volume: 104, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transpl

1999
Long-term follow-up results of adult patients with acute lymphocytic leukemia or lymphoblastic lymphoma treated with short-term, alternating non-cross-resistant chemotherapy: Japan Clinical Oncology Group Study 8702. Lymphoma Study Group.
    Japanese journal of clinical oncology, 1999, Volume: 29, Issue:7

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cyclophospham

1999
Fractionated cyclophosphamide added to the IVAP regimen (idarubicin-vincristine-L-asparaginase-prednisone) could lower the risk of primary refractory disease in T-lineage but not B-lineage acute lymphoblastic leukemia: first results from a phase II clinic
    Haematologica, 1999, Volume: 84, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Burkitt Lymph

1999
Effects of G-CSF and high-dose methylprednisolone on peripheral stem cells, serum IL-3 levels and hematological parameters in acute lymphoblastic leukemia patients with neutropenia: a pilot study.
    Leukemia research, 2000, Volume: 24, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamid

2000
Benefit of intensified treatment for all children with acute lymphoblastic leukaemia: results from MRC UKALL XI and MRC ALL97 randomised trials. UK Medical Research Council's Working Party on Childhood Leukaemia.
    Leukemia, 2000, Volume: 14, Issue:3

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; C

2000
Improved response with higher corticosteroid dose in children with acute lymphoblastic leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001, Feb-15, Volume: 19, Issue:4

    Topics: Blood Cell Count; Bone Marrow Cells; Child; Child, Preschool; Dexamethasone; Dose-Response Relations

2001
Determinants of outcome after intensified therapy of childhood lymphoblastic leukaemia: results from Medical Research Council United Kingdom acute lymphoblastic leukaemia XI protocol.
    British journal of haematology, 2001, Volume: 113, Issue:1

    Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child,

2001
Outcome of acute lymphoblastic leukemia in children with AL90 regimen: impact of response to treatment and sex difference on prognostic factors.
    Medical and pediatric oncology, 2001, Volume: 37, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; C

2001
Analysis of 20-year follow-up study of LVP regimen for adult acute lymphoblastic leukemia.
    International journal of hematology, 2001, Volume: 74, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Female; Follo

2001
Induction therapy by frequent administration of doxorubicin with four other drugs, followed by intensive consolidation and maintenance therapy for adult acute lymphoblastic leukemia: the JALSG-ALL93 study.
    Leukemia, 2002, Volume: 16, Issue:7

    Topics: Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marr

2002
Adult lymphoblastic lymphoma: high incidence of central nervous system relapse in patients treated with the Stanford University protocol.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1992, Volume: 3, Issue:10

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Brain Neoplasms; Cy

1992
Treatment of advanced stage T cell lymphoblastic lymphoma: results of the United Kingdom Children's Cancer Study Group (UKCCSG) protocol 8503.
    British journal of haematology, 1992, Volume: 82, Issue:2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantatio

1992
Treatment of adult acute lymphoblastic leukaemia (ALL) over a 16 year period.
    Leukemia, 1992, Volume: 6 Suppl 2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cytarabine; D

1992
Retrospective analysis of late intensification therapy with high-dose methotrexate for standard-risk acute lymphoblastic leukemia in childhood (CCLSG-S811 study). The Children's Cancer and Leukemia Study Group.
    International journal of hematology, 1991, Volume: 54, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cranial Irradiation; Humans

1991
Remission induction and continuation therapy in children with their first relapse of acute lymphoid leukemia. A Pediatric Oncology Group study.
    Cancer, 1991, Jan-01, Volume: 67, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Doxorubicin; Follow-Up Stud

1991
[Results of 16-year use of the 06-Paris-LA-66 program in the treatment of children with acute lymphoblastic leukemia].
    Gematologiia i transfuziologiia, 1991, Volume: 36, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Daunorubicin; H

1991
Intensive chemotherapy for acute lymphoblastic leukaemia in adults.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Combined Modality T

1990
Impact of early intensive reinduction therapy on event-free survival in children with low-risk acute lymphoblastic leukemia.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Cyclophosphamide; Daunorubicin;

1990
Treatment of childhood acute lymphoblastic leukemia with protocol TCL821: a report of Taiwan Children's Cancer Study Group.
    Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association, 1989, Volume: 88, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; C

1989
A comparison of two regimens for high-risk acute lymphocytic leukemia in childhood. A Pediatric Oncology Group Study.
    Cancer, 1989, Jan-01, Volume: 63, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Presc

1989
[Treatment of childhood acute leukemia: a long-term follow-up study of CCLSG-high risk ALL 811 (phase III study). Children's Cancer & Leukemia Study Group].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1988, Volume: 29, Issue:9

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Clinical Trials

1988

Other Studies

245 other studies available for prednisolone and Acute Lymphoid Leukemia

ArticleYear
Antileukemic Effects of Anti-miR-146a, Anti-miR-155, Anti-miR-181a, and Prednisolone on Childhood Acute Lymphoblastic Leukemia.
    BioMed research international, 2021, Volume: 2021

    Topics: Antineoplastic Agents; Apoptosis; B-Lymphocytes; Cell Cycle; Cell Line; Cell Line, Tumor; Cell Proli

2021
The incidence of symptomatic osteonecrosis is similar between Japanese children and children in Western countries with acute lymphoblastic leukaemia treated with a Berlin-Frankfurt-Münster (BFM)95-based protocol.
    British journal of haematology, 2022, Volume: 196, Issue:5

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; C

2022
Early and Very Early GRIM19 and MCL1 Expression Are Correlated to Late Acquired Prednisolone Effects in a T-Cell Acute Leukemia Cell Line.
    Advances in experimental medicine and biology, 2021, Volume: 1339

    Topics: Apoptosis; Cell Line; Cell Line, Tumor; Drug Resistance, Neoplasm; Humans; Myeloid Cell Leukemia Seq

2021
Targeting Glutaminolysis Shows Efficacy in Both Prednisolone-Sensitive and in Metabolically Rewired Prednisolone-Resistant B-Cell Childhood Acute Lymphoblastic Leukaemia Cells.
    International journal of molecular sciences, 2023, Feb-08, Volume: 24, Issue:4

    Topics: Child; Drug Resistance, Neoplasm; Glucocorticoids; Glutamine; Humans; Precursor Cell Lymphoblastic L

2023
Identification of Hub Genes Associated with Resistance to Prednisolone in Acute Lymphoblastic Leukemia Based on Weighted Gene Co-expression Network Analysis.
    Molecular biotechnology, 2023, Volume: 65, Issue:11

    Topics: Gene Expression Profiling; Gene Regulatory Networks; Humans; Inflammation; Precursor Cell Lymphoblas

2023
Steroid-induced ocular hypertensive response in pediatric patients with acute lymphoblastic leukemia.
    Japanese journal of ophthalmology, 2023, Volume: 67, Issue:4

    Topics: Adrenal Cortex Hormones; Child; Child, Preschool; Female; Glaucoma; Glucocorticoids; Humans; Intraoc

2023
Prednisolone Prophase for a Week Versus Upfront Multiagent Chemotherapy in Childhood Acute Lymphoblastic Leukemia: An Analysis With Reference to Induction Mortality in a Developing Country.
    Journal of pediatric hematology/oncology, 2020, Volume: 42, Issue:3

    Topics: Adolescent; Antineoplastic Agents, Hormonal; Child; Child, Preschool; Developing Countries; Disease-

2020
Reciprocal Regulation of HSD11B1 and HSD11B2 Predicts Glucocorticoid Sensitivity in Childhood Acute Lymphoblastic Leukemia.
    The Journal of pediatrics, 2020, Volume: 220

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adolescent

2020
Genetic polymorphisms and vincristine-induced peripheral neuropathy in patients treated with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone therapy.
    International journal of hematology, 2020, Volume: 111, Issue:5

    Topics: Antigens, Surface; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytochrome P-45

2020
Apoptosis Induced by Prednisolone Occurs without Altering the Promoter Methylation of BAX and BCL-2 Genes in Acute Lymphoblastic Leukemia Cells CCRF-CEM.
    Asian Pacific journal of cancer prevention : APJCP, 2020, Feb-01, Volume: 21, Issue:2

    Topics: Antineoplastic Agents, Hormonal; Apoptosis; bcl-2-Associated X Protein; Cell Line, Tumor; DNA Methyl

2020
L-asparaginase-induced Parotitis in an Elderly Patient with Acute Lymphoblastic Leukemia.
    Internal medicine (Tokyo, Japan), 2020, Jul-15, Volume: 59, Issue:14

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cyclophosphamide; Daunorubicin;

2020
Clinicoepidemiologic Profile and Outcome Predicted by Minimal Residual Disease in Children With Mixed-phenotype Acute Leukemia Treated on a Modified MCP-841 Protocol at a Tertiary Cancer Institute in India.
    Journal of pediatric hematology/oncology, 2020, Volume: 42, Issue:7

    Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool;

2020
Comparison of myelosuppression using the D-index between children and adolescents/young adults with acute lymphoblastic leukemia during induction chemotherapy.
    Pediatric blood & cancer, 2021, Volume: 68, Issue:2

    Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bac

2021
Outcomes of pediatric mixed phenotype acute leukemia treated with lymphoid directed therapy: Analysis of an institutional series from India.
    Pediatric hematology and oncology, 2021, Volume: 38, Issue:4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Daunorubicin; Femal

2021
Faecal microbiota transplant: a novel biological approach to extensively drug-resistant organism-related non-relapse mortality.
    Bone marrow transplantation, 2017, Volume: 52, Issue:10

    Topics: Allografts; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bacteria; Daunorubicin; Dr

2017
EgoNet identifies differential ego-modules and pathways related to prednisolone resistance in childhood acute lymphoblastic leukemia.
    Hematology (Amsterdam, Netherlands), 2018, Volume: 23, Issue:4

    Topics: Child, Preschool; Drug Resistance, Neoplasm; Gene Expression Profiling; Glucocorticoids; Humans; Pre

2018
10-year complete remission in a Philadelphia chromosome-positive acute lymphoblastic leukemia patient using imatinib without high-intensity chemotherapy or allogeneic stem cell transplantation.
    International journal of hematology, 2018, Volume: 107, Issue:6

    Topics: Drug Therapy, Combination; Female; Humans; Imatinib Mesylate; Middle Aged; Precursor Cell Lymphoblas

2018
Demographics and Outome in Paediatric Non-Hodgkin Lymphoma: Single Centre Experience at The Children Hospital Lahore, Pakistan.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2018, Volume: 28, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Child; Child, Preschoo

2018
Regulatory effect of resveratrol and prednisolone on MDR1 gene expression in acute lymphoblastic leukemia cell line (CCRF-CEM): An epigenetic perspective.
    Journal of cellular biochemistry, 2018, Volume: 119, Issue:6

    Topics: ATP Binding Cassette Transporter, Subfamily B; Cell Line, Tumor; Epigenesis, Genetic; Gene Expressio

2018
T-cell-replete haploidentical stem cell transplantation using low-dose antithymocyte globulin in children with relapsed or refractory acute leukemia.
    International journal of hematology, 2018, Volume: 108, Issue:1

    Topics: Adolescent; Antilymphocyte Serum; Child; Child, Preschool; Female; Follow-Up Studies; Graft vs Host

2018
Paraneoplastic Demyelinating Sensorimotor Neuropathy Delaying the Diagnosis of an Underlying Acute Lymphoblastic Leukemia in a Child.
    Journal of oncology practice, 2018, Volume: 14, Issue:10

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Brain; Child; D

2018
Evaluation of BAX and BCL-2 Gene Expression and Apoptosis Induction in Acute Lymphoblastic Leukemia Cell Line CCRFCEM after High- Dose Prednisolone Treatment
    Asian Pacific journal of cancer prevention : APJCP, 2018, Aug-24, Volume: 19, Issue:8

    Topics: Antineoplastic Agents, Hormonal; Apoptosis; bcl-2-Associated X Protein; Gene Expression Regulation,

2018
Dasatinib and low-intensity chemotherapy for Philadelphia chromosome-positive acute lymphoblastic leukemia in a child with Down syndrome.
    Pediatric blood & cancer, 2019, Volume: 66, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Dasatinib; Down Syndrome; Female; Humans; Phi

2019
NK Cells as Possible Prognostic Factor in Childhood Acute Lymphoblastic Leukemia.
    Disease markers, 2019, Volume: 2019

    Topics: Antigens, CD; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Child; Child, Preschool; Female; H

2019
Regulatory Effect of Resveratrol and Prednisolone on MDR1\ Protein Expression in Acute Lymphoblastic Leukemia Cell\ Line (CCRF-CEM)
    Asian Pacific journal of cancer prevention : APJCP, 2019, Apr-29, Volume: 20, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; ATP Binding Cassette Transporter, Subfami

2019
Acetabular avascular necrosis following high-dose steroid treatment and chemotherapy for leukemia : Computer tomography analysis of treatment with impaction bone grafting.
    Skeletal radiology, 2020, Volume: 49, Issue:1

    Topics: Acetabulum; Antineoplastic Combined Chemotherapy Protocols; Bone Density; Bone Transplantation; Cure

2020
[Recurring Sweet syndrome in a patient with Philadelphia chromosome-positive acute lymphoblastic leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2019, Volume: 60, Issue:6

    Topics: Aged; Angina, Unstable; Granulocyte Colony-Stimulating Factor; Humans; Male; Neutropenia; Percutaneo

2019
Long-term outcomes of modified BFM-95 regimen in adults with newly diagnosed standard-risk acute lymphoblastic leukemia: a retrospective single-center study.
    International journal of hematology, 2019, Volume: 110, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Asian People; Asparaginase; Cohort Studies; C

2019
[Steroid intake before leukemia diagnosis impairs outcome in childhood acute lymphoblastic leukemia].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2013, Volume: 20, Issue:4

    Topics: Adolescent; Child; Child, Preschool; Female; Glucocorticoids; Humans; Infant; Male; Precursor Cell L

2013
Nasolacrimal system obstruction, ptosis and esotropia due to chemotherapy in acute lymphoblastic leukemia.
    Cutaneous and ocular toxicology, 2013, Volume: 32, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Blepharoptosis; Child; Daunorubicin; E

2013
[Kaposiform haemangioendothelioma associated with B-cell acute lymphoblastic leukemia].
    Annales de dermatologie et de venereologie, 2013, Volume: 140, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Biopsy; Combined Modality Therapy

2013
Outcome of patients with acute lymphoblastic leukemia (ALL) following induction therapy with a modified (pulsed dexamethasone rather than continuous prednisone) UKALL XII/ECOG E2993 protocol at Tawam Hospital, United Arab Emirates (UAE).
    Medical oncology (Northwood, London, England), 2013, Volume: 30, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cancer Care Facilit

2013
Deregulated MIR335 that targets MAPK1 is implicated in poor outcome of paediatric acute lymphoblastic leukaemia.
    British journal of haematology, 2013, Volume: 163, Issue:1

    Topics: Cell Line, Tumor; Child; Child, Preschool; Computational Biology; Drug Resistance, Neoplasm; Female;

2013
Chemical genomic screening identifies LY294002 as a modulator of glucocorticoid resistance in MLL-rearranged infant ALL.
    Leukemia, 2014, Volume: 28, Issue:4

    Topics: Cell Line, Tumor; Chromones; Drug Resistance; Gene Rearrangement; Genomics; Glucocorticoids; Histone

2014
[Evaluation of the efficacy of two successive protocols on pediatric acute lymphoblastic leukemia with E2A-PBX1 fusion gene].
    Zhonghua er ke za zhi = Chinese journal of pediatrics, 2013, Volume: 51, Issue:6

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Daunorubicin; D

2013
Assessment of corticosteroid-induced osteonecrosis in children undergoing chemotherapy for acute lymphoblastic leukemia: a report from the Japanese Childhood Cancer and Leukemia Study Group.
    Journal of pediatric hematology/oncology, 2014, Volume: 36, Issue:1

    Topics: Adolescent; Adrenal Cortex Hormones; Antineoplastic Combined Chemotherapy Protocols; Asian People; C

2014
The synergism of MCL1 and glycolysis on pediatric acute lymphoblastic leukemia cell survival and prednisolone resistance.
    Haematologica, 2013, Volume: 98, Issue:12

    Topics: Antineoplastic Agents, Hormonal; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, N

2013
[Clinical characteristics and efficacy analysis for patients over 55 years of age with acute lymphoblastic leukemia].
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2013, Dec-18, Volume: 45, Issue:6

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy;

2013
Glucocorticoid sensitisation in Mixed Lineage Leukaemia-rearranged acute lymphoblastic leukaemia by the pan-BCL-2 family inhibitors gossypol and AT-101.
    European journal of cancer (Oxford, England : 1990), 2014, Volume: 50, Issue:9

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Dose-Response Relationshi

2014
The long-term results of childhood acute lymphoblastic leukemia at two centers from Turkey: 15 years of experience with the ALL-BFM 95 protocol.
    Annals of hematology, 2014, Volume: 93, Issue:10

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; C

2014
Early use of allogeneic hematopoietic stem cell transplantation for infants with MLL gene-rearrangement-positive acute lymphoblastic leukemia.
    Leukemia, 2015, Volume: 29, Issue:2

    Topics: Antineoplastic Agents; Child, Preschool; Disease-Free Survival; Female; Gene Rearrangement; Hematopo

2015
The synthetic glucocorticoids prednisolone and dexamethasone regulate the same genes in acute lymphoblastic leukemia cells.
    BMC genomics, 2014, Aug-07, Volume: 15

    Topics: Apoptosis; Child; Dexamethasone; Genes, Neoplasm; Glucocorticoids; Humans; Jurkat Cells; Precursor C

2014
Idiopathic Hyperammonemia That Developed During Initial Treatment With Steroid in a Patient With Newly Diagnosed Leukemia.
    Journal of pediatric hematology/oncology, 2015, Volume: 37, Issue:6

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Hydrocortisone; Hype

2015
Safe and effective dosing of basal-bolus insulin in patients receiving high-dose steroids for hyper-cyclophosphamide, doxorubicin, vincristine, and dexamethasone chemotherapy.
    Diabetes technology & therapeutics, 2014, Volume: 16, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Body Mass Index; Can

2014
Expression of certain leukemia/lymphoma related microRNAs and its correlation with prognosis in childhood acute lymphoblastic leukemia.
    Pathology oncology research : POR, 2015, Volume: 21, Issue:3

    Topics: Adolescent; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Bone Marrow; Child; Child, Preschool

2015
Towards personalized therapy in pediatric acute lymphoblastic leukemia: RAS mutations and prednisolone resistance.
    Haematologica, 2015, Volume: 100, Issue:4

    Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Child; Drug Resistance, Neoplasm; Genes

2015
Clinical features and prognostic significance of TCF3-PBX1 fusion gene in Chinese children with acute lymphoblastic leukemia by using a modified ALL-BFM-95 protocol.
    Pediatric hematology and oncology, 2015, Volume: 32, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asian People; Asparaginase; Child; Child, Preschool;

2015
Imatinib-induced Severe Hepatitis in a 9-Year-old Girl With Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia.
    Journal of pediatric hematology/oncology, 2015, Volume: 37, Issue:6

    Topics: Adult; Anti-Inflammatory Agents; Antineoplastic Agents; Benzamides; Child; Female; Hepatitis; Humans

2015
NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells.
    Nature genetics, 2015, Volume: 47, Issue:6

    Topics: Adolescent; Antineoplastic Agents, Hormonal; Base Sequence; Carrier Proteins; Caspase 1; Child; Chil

2015
Increasing aclarubicin dose in low-dose cytarabine and aclarubicin in combination with granulocyte colony-stimulating factor (CAG regimen) is efficacious as salvage chemotherapy for relapsed/refractory mixed-phenotype acute leukemia.
    Leukemia research, 2015, Volume: 39, Issue:8

    Topics: Aclarubicin; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Child,

2015
Orbital mass secondary to infantile acute lymphoblastic leukaemia.
    BMJ case reports, 2016, May-03, Volume: 2016

    Topics: Antineoplastic Agents; Diagnosis, Differential; Female; Humans; Infant; Orbital Neoplasms; Precursor

2016
Two Elderly Patients with Philadelphia Chromosome Positive Mixed Phenotype Acute Leukemia Who Were Successfully Treated with Dasatinib and Prednisolone.
    Internal medicine (Tokyo, Japan), 2016, Volume: 55, Issue:9

    Topics: Acute Disease; Aged; Dasatinib; Drug Therapy, Combination; Female; Humans; Phenotype; Philadelphia C

2016
IKZF1 deletion is enriched in pediatric B-cell precursor acute lymphoblastic leukemia patients showing prednisolone resistance.
    Leukemia, 2016, Volume: 30, Issue:8

    Topics: B-Lymphocytes; Child; Glucocorticoids; Humans; Ikaros Transcription Factor; Precursor Cell Lymphobla

2016
The Effect of Prednisolone on miR 15a and miR16-1 Expression Levels and Apoptosis in Acute Lymphoblastic Leukemia Cell Line: CCRF-CEM.
    Drug research, 2016, Volume: 66, Issue:8

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Humans; MicroRNAs; Precursor Cell Lymphoblastic

2016
Significance of the complete clearance of peripheral blasts after 7 days of prednisolone treatment in children with acute lymphoblastic leukemia: the Tokyo Children's Cancer Study Group Study L99-15.
    Haematologica, 2008, Volume: 93, Issue:8

    Topics: Adolescent; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Blast C

2008
In vitro cellular drug sensitivity at diagnosis is correlated to minimal residual disease at end of induction therapy in childhood acute lymphoblastic leukemia.
    Leukemia research, 2009, Volume: 33, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Doxorubicin; Hu

2009
Treatment of children with acute lymphoblastic leukemia in India using a BFM protocol.
    Pediatric blood & cancer, 2008, Volume: 51, Issue:5

    Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Pre

2008
Oral mucositis in acute lymphoblastic leukaemia: analysis of 169 paediatric patients.
    Oral diseases, 2008, Volume: 14, Issue:8

    Topics: Adolescent; Age Factors; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplasti

2008
Severe neurotoxicities in a case of Charcot-Marie-Tooth disease type 2 caused by vincristine for acute lymphoblastic leukemia.
    Journal of pediatric hematology/oncology, 2008, Volume: 30, Issue:7

    Topics: Adolescent; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Aspar

2008
Veno-occlusive disease of the liver during induction therapy for acute lymphoblastic leukemia.
    International journal of hematology, 2008, Volume: 88, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Daunorubicin; Female; Fibrinolytic Age

2008
Inhibition of glycolysis modulates prednisolone resistance in acute lymphoblastic leukemia cells.
    Blood, 2009, Feb-26, Volume: 113, Issue:9

    Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Daunorubicin; Deoxy

2009
The SWI/SNF chromatin-remodeling complex and glucocorticoid resistance in acute lymphoblastic leukemia.
    Journal of the National Cancer Institute, 2008, Dec-17, Volume: 100, Issue:24

    Topics: Antineoplastic Agents, Hormonal; Blotting, Western; Child; Child, Preschool; Chromosomal Proteins, N

2008
Chemo-sensitivity in a panel of B-cell precursor acute lymphoblastic leukemia cell lines, YCUB series, derived from children.
    Leukemia research, 2009, Volume: 33, Issue:10

    Topics: Antineoplastic Agents; B-Lymphocytes; Cell Division; Cell Line, Tumor; Cell Survival; Child; Child,

2009
Successful treatment of human metapneumovirus pneumonia using combination therapy with intravenous ribavirin and immune globulin.
    British journal of haematology, 2009, Volume: 145, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Asparaginase; Child, Preschool; Co

2009
Changes in the MDR1 gene expression after short-term ex vivo therapy with prednisolone have prognostic impact in childhood acute lymphoblastic leukemia.
    Annals of hematology, 2009, Volume: 88, Issue:12

    Topics: Adolescent; Antineoplastic Agents, Hormonal; ATP Binding Cassette Transporter, Subfamily B; ATP Bind

2009
Prednisolone exerts late mitogenic and biphasic effects on resistant acute lymphoblastic leukemia cells: Relation to early gene expression.
    Leukemia research, 2009, Volume: 33, Issue:12

    Topics: Base Sequence; Cell Line, Tumor; Cell Proliferation; DNA Primers; Gene Expression; Humans; Mitogens;

2009
Pyruvate kinase M2 and prednisolone resistance in acute lymphoblastic leukemia.
    Haematologica, 2009, Volume: 94, Issue:9

    Topics: Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulati

2009
Simultaneous isolated bilateral facial palsy: a rare vincristine-associated toxicity.
    Indian journal of medical sciences, 2009, Volume: 63, Issue:8

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Facial Pa

2009
Cutaneous Mycobacterium intracellulare infection in a bone marrow transplantation recipient.
    The Journal of dermatology, 2010, Volume: 37, Issue:2

    Topics: Bone Marrow Transplantation; Clarithromycin; Graft vs Host Disease; Humans; Immunocompromised Host;

2010
Spinal cord compression by epidural involvement over 21 vertebral levels in acute lymphoblastic leukemia.
    Journal of pediatric hematology/oncology, 2011, Volume: 33, Issue:2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Dexamethas

2011
Skeletal morbidity in children receiving chemotherapy for acute lymphoblastic leukaemia.
    Archives of disease in childhood, 2010, Volume: 95, Issue:10

    Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Bone Diseases; Child; Child

2010
Membranoproliferative glomerulonephritis following allogeneic hematopoietic stem cell transplantation.
    Clinical and experimental nephrology, 2010, Volume: 14, Issue:6

    Topics: Adult; Azathioprine; Glomerulonephritis, Membranoproliferative; Graft vs Host Disease; Hematopoietic

2010
Childhood acute lymphoblastic leukemia in Turkey: factors influencing treatment and outcome: a single center experience.
    Journal of pediatric hematology/oncology, 2010, Volume: 32, Issue:8

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; C

2010
Growth in children with acute lymphoblastic leukemia during treatment.
    Journal of pediatric hematology/oncology, 2010, Volume: 32, Issue:8

    Topics: Antineoplastic Agents, Hormonal; Body Mass Index; Child; Child, Preschool; Combined Modality Therapy

2010
In vitro cellular drug resistance adds prognostic information to other known risk-factors in childhood acute lymphoblastic leukemia.
    Leukemia research, 2011, Volume: 35, Issue:4

    Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells

2011
Intrapericardial steroid treatment for recurrent pericardial effusion in a patient with acute lymphoblastic Leukaemia.
    Hematological oncology, 2011, Volume: 29, Issue:4

    Topics: Adolescent; Female; Humans; Injections; Pericardial Effusion; Precursor Cell Lymphoblastic Leukemia-

2011
Identification of prognostic protein biomarkers in childhood acute lymphoblastic leukemia (ALL).
    Journal of proteomics, 2011, May-16, Volume: 74, Issue:6

    Topics: Biomarkers, Tumor; Cell Line, Tumor; Child; Child, Preschool; Cofilin 1; Disease-Free Survival; Fema

2011
[A case of the association of acute lymphoblastic lymphoma with active tuberculosis in the child: a Malian case].
    Le Mali medical, 2010, Volume: 25, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Antitubercular Ag

2010
[Acute lymphoblastic leukemia complicated with varicella zoster virus meningoencephalitis and visceral dissemination after related bone marrow transplantation].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2011, Volume: 52, Issue:5

    Topics: Acute Kidney Injury; Acyclovir; Adult; Antiviral Agents; Bone Marrow Transplantation; Chronic Diseas

2011
Expression of 11beta-hydroxysteroid dehydrogenase 2 contributes to glucocorticoid resistance in lymphoblastic leukemia cells.
    Leukemia research, 2011, Volume: 35, Issue:12

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Antineoplastic Agents, Hormonal; Cell Line, Tumor; Dexa

2011
Polymorphism in the PAI-1 (SERPINE1) gene and the risk of osteonecrosis in children with acute lymphoblastic leukemia.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Clinical Trials as

2011
Early occurrence of nephrotic syndrome associated with cord blood stem cell transplantation.
    Clinical and experimental nephrology, 2012, Volume: 16, Issue:1

    Topics: Bone Marrow Transplantation; Child; Child, Preschool; Cord Blood Stem Cell Transplantation; Graft vs

2012
Proteasome chymotrypsin-like activity in plasma as a useful marker for children with acute lymphoblastic leukemia.
    Scandinavian journal of clinical and laboratory investigation, 2012, Volume: 72, Issue:1

    Topics: Adolescent; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Case-Control Studies; Child; Child,

2012
Clinical impact of in vitro cellular drug resistance on childhood acute lymphoblastic leukemia in Taiwan.
    Leukemia & lymphoma, 2012, Volume: 53, Issue:8

    Topics: Adolescent; Antineoplastic Agents; Asparaginase; Child; Child, Preschool; Drug Resistance, Neoplasm;

2012
Elevated S100A8/S100A9 expression causes glucocorticoid resistance in MLL-rearranged infant acute lymphoblastic leukemia.
    Leukemia, 2012, Volume: 26, Issue:6

    Topics: Apoptosis; Blotting, Western; Calgranulin A; Calgranulin B; Drug Resistance, Neoplasm; Flow Cytometr

2012
C-type Natriuretic Peptide: a novel biomarker of steroid induced bone toxicity in children with acute lymphoblastic leukemia (ALL).
    Peptides, 2012, Volume: 36, Issue:1

    Topics: Alkaline Phosphatase; Antineoplastic Agents; Biomarkers; Body Height; Bone and Bones; Bone Developme

2012
Higher expression of the novel gene upregulated gene 4 in two acute lymphoblastic leukemia patients with poor prednisolone response.
    Acta haematologica, 2012, Volume: 128, Issue:2

    Topics: Base Sequence; Child; DNA Primers; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Neo

2012
Diagnostic paracentesis in an acute lymphoblastic leukemia child without characteristic symptoms of pancreatitis.
    Journal of pediatric hematology/oncology, 2013, Volume: 35, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Epirubicin; Humans; Male; Pancr

2013
Combination of prednisolone and low dosed dexamethasone exhibits greater in vitro antileukemic activity than equiactive dose of prednisolone and overcomes prednisolone drug resistance in acute childhood lymphoblastic leukemia.
    Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2014, Volume: 158, Issue:3

    Topics: Child; Dexamethasone; Drug Resistance, Neoplasm; Drug Therapy, Combination; Glucocorticoids; Humans;

2014
Comparison of prognostic value of in vitro drug resistance and bone marrow residual disease on day 15 of therapy in childhood acute lymphoblastic leukemia.
    Anticancer research, 2012, Volume: 32, Issue:12

    Topics: Adolescent; Antineoplastic Agents; Asparaginase; Bone Marrow; Child; Child, Preschool; Daunorubicin;

2012
Src kinase-induced phosphorylation of annexin A2 mediates glucocorticoid resistance in MLL-rearranged infant acute lymphoblastic leukemia.
    Leukemia, 2013, Volume: 27, Issue:5

    Topics: Annexin A2; Benzodioxoles; Cell Proliferation; Drug Resistance, Neoplasm; Gene Rearrangement; Histon

2013
Successful treatment of a pregnant woman with Philadelphia chromosome-positive acute lymphoblastic leukemia.
    International journal of hematology, 2013, Volume: 97, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Daunorubicin; Female; Human

2013
A successful second unrelated BMT (UBMT) from a different unrelated donor to treat ALL that relapsed after the initial UBMT.
    American journal of hematology, 2002, Volume: 71, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Azathioprine; Bone Marrow Trans

2002
Cutaneous lymphocytic vasculitis as the presenting feature of acute lymphoblastic leukemia.
    Journal of pediatric hematology/oncology, 2002, Volume: 24, Issue:7

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Biopsy; Bone Marrow; Child; Humans; Precursor Cell Lym

2002
Post-induction residual disease in translocation t(12;21)-positive childhood ALL.
    Medical and pediatric oncology, 2003, Volume: 40, Issue:2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Chromosomes, Hu

2003
Endogenous fungal retinitis in a patient with acute lymphocytic leukemia manifesting as uveitis and optic nerve lesion.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2002, Volume: 120, Issue:12

    Topics: Antineoplastic Agents; Child, Preschool; Eye Enucleation; Eye Infections, Fungal; Glucocorticoids; H

2002
Benign intracranial hypertension in association with acute lymphoblastic leukemia.
    Pediatric hematology and oncology, 2003, Volume: 20, Issue:2

    Topics: Acetazolamide; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Chlorthalid

2003
Impaired adrenal function after glucocorticoid therapy in children with acute lymphoblastic leukemia.
    Medical and pediatric oncology, 2003, Volume: 41, Issue:2

    Topics: Adolescent; Adrenal Glands; Adrenal Insufficiency; Antineoplastic Agents, Hormonal; Antineoplastic A

2003
Resistance to different classes of drugs is associated with impaired apoptosis in childhood acute lymphoblastic leukemia.
    Blood, 2003, Dec-15, Volume: 102, Issue:13

    Topics: Antineoplastic Agents; Apoptosis; Asparaginase; Caspase 3; Caspases; Child; Daunorubicin; Drug Resis

2003
Patient stratification based on prednisolone-vincristine-asparaginase resistance profiles in children with acute lymphoblastic leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Sep-01, Volume: 21, Issue:17

    Topics: Adolescent; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Antineoplastic Combi

2003
[Tumor lysis syndrome in the course of acute lymphoblastic leukemia as the consequence of prednisone monotherapy].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2003, Volume: 15, Issue:86

    Topics: Adolescent; Anti-Inflammatory Agents; Female; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma

2003
Intraocular pressure profile of a child on a systemic corticosteroid.
    American journal of ophthalmology, 2004, Volume: 137, Issue:1

    Topics: Administration, Oral; Child; Female; Glucocorticoids; Humans; Intraocular Pressure; Ocular Hypertens

2004
Gene-expression patterns in drug-resistant acute lymphoblastic leukemia cells and response to treatment.
    The New England journal of medicine, 2004, Aug-05, Volume: 351, Issue:6

    Topics: Antineoplastic Agents; Asparaginase; Child; Child, Preschool; Daunorubicin; Disease-Free Survival; D

2004
An extra X chromosome as a sole abnormality in relapse of an adult acute lymphoblastic leukemia.
    Cancer genetics and cytogenetics, 2004, Volume: 155, Issue:2

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Ant

2004
In vitro drug sensitivity and expression profiling for disease prognostication in childhood acute lymphoblastic leukaemia (ALL): an exploratory model using cell lines.
    Annals of the Academy of Medicine, Singapore, 2004, Volume: 33, Issue:5 Suppl

    Topics: Antineoplastic Agents, Hormonal; Cell Line, Tumor; Child; Drug Screening Assays, Antitumor; Gene Exp

2004
[Treatment results with ALL-BFM-95 protocol in children with acute lymphoblastic leukemia in Hungary].
    Orvosi hetilap, 2005, Jan-09, Volume: 146, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophospham

2005
Identification of genes associated with chemotherapy crossresistance and treatment response in childhood acute lymphoblastic leukemia.
    Cancer cell, 2005, Volume: 7, Issue:4

    Topics: Age Factors; Antineoplastic Agents; Asparaginase; Cell Survival; Child; Cluster Analysis; Core Bindi

2005
Expression levels of TEL, AML1, and the fusion products TEL-AML1 and AML1-TEL versus drug sensitivity and clinical outcome in t(12;21)-positive pediatric acute lymphoblastic leukemia.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Apr-15, Volume: 11, Issue:8

    Topics: Asparaginase; Cell Survival; Child; Chromosomes, Human, Pair 12; Chromosomes, Human, Pair 21; Core B

2005
Chemotherapy-induced palmer planter erythrodysesthesia.
    The Journal of the Association of Physicians of India, 2005, Volume: 53

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Drug Eruptions; Erythema; F

2005
No difference between prednisolone and dexamethasone treatment in bone mineral density and growth in long term survivors of childhood acute lymphoblastic leukemia.
    Pediatric blood & cancer, 2006, Volume: 46, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Agents, Hormonal; Body Composition; Bone Density; Child; Child, Pr

2006
In vitro activity of imatinib in cells from patients with adult acute lymphoblastic leukemia.
    Anti-cancer drugs, 2005, Volume: 16, Issue:6

    Topics: Adult; Antineoplastic Agents; Asparaginase; Benzamides; Cell Survival; Cytarabine; Daunorubicin; Dru

2005
Outcome after first relapse in childhood acute lymphoblastic leukaemia - lessons from the United Kingdom R2 trial.
    British journal of haematology, 2005, Volume: 130, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Child; Co

2005
Alternative medicine remedies might stimulate viability of leukemic cells.
    Pediatric blood & cancer, 2006, Volume: 46, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Case-Control Studies; Cat's C

2006
Genetic variations in the glucocorticoid receptor gene are not related to glucocorticoid resistance in childhood acute lymphoblastic leukemia.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Aug-15, Volume: 11, Issue:16

    Topics: Base Sequence; Cell Survival; Child; Child, Preschool; DNA Mutational Analysis; DNA, Neoplasm; Drug

2005
Expression of the glucocorticoid receptor and its isoforms in relation to glucocorticoid resistance in childhood acute lymphocytic leukemia.
    Haematologica, 2005, Volume: 90, Issue:9

    Topics: Child; Cohort Studies; Drug Resistance, Neoplasm; Gene Expression Regulation; Glucocorticoids; Human

2005
Loss of heterozygosity and somatic mutations of the glucocorticoid receptor gene are rarely found at relapse in pediatric acute lymphoblastic leukemia but may occur in a subpopulation early in the disease course.
    Cancer research, 2005, Nov-01, Volume: 65, Issue:21

    Topics: Alleles; Bone Marrow; Cell Line, Tumor; Child; Child, Preschool; Cohort Studies; Exons; Gene Deletio

2005
Clinical impact of corticosteroid-induced adrenal suppression during treatment for acute lymphoblastic leukemia in children: a prospective observational study using the low-dose adrenocorticotropin test.
    The Journal of pediatrics, 2005, Volume: 147, Issue:5

    Topics: Adolescent; Adrenal Cortex Function Tests; Adrenal Insufficiency; Antineoplastic Agents, Hormonal; C

2005
Body composition in children in remission from acute lymphoblastic leukemia.
    The American journal of clinical nutrition, 2006, Volume: 83, Issue:1

    Topics: Absorptiometry, Photon; Adipose Tissue; Body Composition; Body Mass Index; Body Water; Case-Control

2006
Adolescents with acute lymphoblastic leukaemia: outcome on UK national paediatric (ALL97) and adult (UKALLXII/E2993) trials.
    Pediatric blood & cancer, 2007, Volume: 48, Issue:3

    Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow T

2007
Adolescents with acute lymphoblastic leukaemia: outcome on UK national paediatric (ALL97) and adult (UKALLXII/E2993) trials.
    Pediatric blood & cancer, 2007, Volume: 48, Issue:3

    Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow T

2007
Adolescents with acute lymphoblastic leukaemia: outcome on UK national paediatric (ALL97) and adult (UKALLXII/E2993) trials.
    Pediatric blood & cancer, 2007, Volume: 48, Issue:3

    Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow T

2007
Adolescents with acute lymphoblastic leukaemia: outcome on UK national paediatric (ALL97) and adult (UKALLXII/E2993) trials.
    Pediatric blood & cancer, 2007, Volume: 48, Issue:3

    Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow T

2007
Infections during induction therapy of childhood acute lymphoblastic leukemia--no association to mannose-binding lectin deficiency.
    European journal of haematology, 2006, Volume: 76, Issue:6

    Topics: Adolescent; Age Factors; Allopurinol; Anti-Infective Agents; Antineoplastic Combined Chemotherapy Pr

2006
Glucocorticoid-induced glucocorticoid-receptor expression and promoter usage is not linked to glucocorticoid resistance in childhood ALL.
    Blood, 2006, Aug-01, Volume: 108, Issue:3

    Topics: Adolescent; Apoptosis; Child; Child, Preschool; Drug Resistance, Neoplasm; Female; Gene Expression R

2006
Moyamoya syndrome following childhood acute lymphoblastic leukemia.
    Pediatric blood & cancer, 2007, Volume: 48, Issue:3

    Topics: Adolescent; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cerebral I

2007
Ex vivo modulation of response to prednisolone in childhood acute lymphoblastic leukaemia.
    British journal of haematology, 2006, Volume: 133, Issue:4

    Topics: Antineoplastic Agents, Hormonal; Cell Death; Child; Drug Resistance, Neoplasm; Drug Screening Assays

2006
[Drug sensitivity of tumor cells in varieties of acute childhood leukemia].
    Voprosy onkologii, 2005, Volume: 51, Issue:5

    Topics: Antigens, CD34; Antineoplastic Agents; Apoptosis; Asparagine; Child; Child, Preschool; Cyclophospham

2005
Ex vivo activity of thalidomide in childhood acute leukemia.
    Leukemia & lymphoma, 2006, Volume: 47, Issue:6

    Topics: Angiogenesis Inhibitors; Cell Cycle; Child; Child, Preschool; Cytarabine; Female; Humans; Immunophen

2006
Non-alcoholic steatohepatitis occurring in a patient with T-lymphoblastic lymphoma during chemotherapy including prednisolone.
    Leukemia & lymphoma, 2006, Volume: 47, Issue:7

    Topics: Adult; Antineoplastic Agents; Fatty Liver; Humans; Liver; Lymphoma, T-Cell; Male; Precursor Cell Lym

2006
[Twenty years of treating childhood acute lymphoblastic leukemia].
    Anales de pediatria (Barcelona, Spain : 2003), 2006, Volume: 65, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophospham

2006
Avascular necrosis--an antineoplastic-treatment-related toxicity: the experiences of two institutions.
    Pediatric hematology and oncology, 2006, Volume: 23, Issue:8

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cyclophosphamide; Cytarabi

2006
Beau's lines after chemotherapy for ALL.
    Internal medicine (Tokyo, Japan), 2007, Volume: 46, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Doxorubicin; Humans; Male; Nail

2007
[Superior sagittal sinus thrombosis during remission induction therapy for acute lymphoblastic leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2006, Volume: 47, Issue:12

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Central Nervous System Neoplasm

2006
[Reults of treatment with protocols BFM 90 and BFM 95].
    Medicinski arhiv, 2006, Volume: 60, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophospham

2006
Lack of mitochondrial depolarization by oxidative stress is associated with resistance to buthionine sulfoximine in acute lymphoblastic leukemia cells.
    Leukemia research, 2007, Volume: 31, Issue:9

    Topics: Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Cell Proliferatio

2007
Hyperosmolar non-ketotic syndrome in a child associated with l-asparaginase and prednisolone.
    Pediatrics international : official journal of the Japan Pediatric Society, 2007, Volume: 49, Issue:2

    Topics: Antineoplastic Agents; Asparaginase; Child; Female; Humans; Hyperglycemic Hyperosmolar Nonketotic Co

2007
Almost normal cognitive function in patients during therapy for childhood acute lymphoblastic leukemia without cranial irradiation according to ALL-BFM 95 and COALL 06-97 protocols: results of an Austrian-German multicenter longitudinal study and implicat
    Pediatric hematology and oncology, 2007, Volume: 24, Issue:2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; C

2007
Triple intrathecal therapy without cranial irradiation for central nervous system preventive therapy in childhood acute lymphoblastic leukemia.
    Pediatric blood & cancer, 2008, Volume: 50, Issue:3

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Central Nervous System; Ch

2008
Itraconazole-enhanced vindesine neurotoxicity in adult acute lymphoblastic leukaemia.
    American journal of hematology, 2007, Volume: 82, Issue:10

    Topics: Adult; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy;

2007
A paediatric case of Candida pericarditis and eosophagus stricture during treatment for acute lymphatic leukaemia.
    Acta oncologica (Stockholm, Sweden), 2007, Volume: 46, Issue:6

    Topics: Antineoplastic Agents; Candida albicans; Candidiasis; Child, Preschool; Doxorubicin; Esophageal Sten

2007
Primary testicular precursor B-lymphoblastic lymphoma: a rare entity.
    Leukemia & lymphoma, 2007, Volume: 48, Issue:10

    Topics: Adult; Age Factors; Antigens, CD20; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide

2007
Peripheral ulcerative keratitis with bilateral optic nerve involvement as an initial presentation of acute lymphocytic leukemia in an adult.
    International ophthalmology, 2009, Volume: 29, Issue:1

    Topics: Adult; Corneal Ulcer; Drug Therapy, Combination; Female; Fluoroquinolones; Gatifloxacin; Humans; Int

2009
Interaction between methotrexate and omeprazole in an adolescent with leukemia: a case report.
    Pharmacy world & science : PWS, 2008, Volume: 30, Issue:4

    Topics: Adolescent; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antimetabolites, Antineoplastic; Humans; Ma

2008
Circumvention of glucocorticoid resistance in childhood leukemia.
    Leukemia research, 2008, Volume: 32, Issue:9

    Topics: Cell Proliferation; Child; Dexamethasone; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumo

2008
Treatment of high-risk acute lymphoblastic leukemia in children using the AL851 and ALHR88 protocols: a report from the Kyushu-Yamaguchi Children's Cancer Study Group in Japan.
    Medical and pediatric oncology, 1996, Volume: 26, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; C

1996
Pubertal growth in young adult survivors of childhood leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:10

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Body Height; Brain Neoplasms; C

1995
Can cytotoxic drugs cure subacute sclerosing panencephalitis?
    Lancet (London, England), 1995, Aug-05, Volume: 346, Issue:8971

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Female; Humans; Precursor Cell

1995
The frequency of micronuclei in bone-marrow erythroblasts during the treatment of childhood acute lymphoblastic leukaemia.
    Mutation research, 1993, Volume: 303, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow; Child; Child,

1993
Treatment of poor prognosis non-Hodgkin's lymphoma with intensive, inpatient combination chemotherapy of brief duration: long-term followup.
    Leukemia & lymphoma, 1993, Volume: 10, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide

1993
Drug combination testing in acute lymphoblastic leukemia using the MTT assay.
    Leukemia research, 1995, Volume: 19, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Daunorubicin; Drug Interactions; D

1995
Changes in the oral health of children during treatment for acute lymphoblastic leukaemia.
    International journal of paediatric dentistry, 1994, Volume: 4, Issue:1

    Topics: Adolescent; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Chil

1994
Avascular necrosis of bone following intensified steroid therapy for acute lymphoblastic leukaemia and high-grade malignant lymphoma.
    British journal of haematology, 1994, Volume: 86, Issue:1

    Topics: Adolescent; Adult; Dexamethasone; Humans; Knee Joint; Lymphoma, Non-Hodgkin; Magnetic Resonance Imag

1994
[The effect of polychemotherapy on hemopoiesis in acute lymphoblastic leukemia in children].
    Gematologiia i transfuziologiia, 1993, Volume: 38, Issue:5

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow; Child; Child,

1993
Diabetes mellitus and pancreatitis as a complication of L-asparaginase therapy.
    Indian pediatrics, 1993, Volume: 30, Issue:6

    Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Diabetes Mellitu

1993
[Treatment of acute lymphoblastic leukemia in adults by the modified protocol of L-10M (Sloan-Kettering): long-term outcome].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1994, Volume: 35, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Fe

1994
Liver function studies in children with acute lymphocytic leukemia after cessation of therapy.
    Medical and pediatric oncology, 1994, Volume: 23, Issue:2

    Topics: Adolescent; Adult; Alanine Transaminase; Antineoplastic Combined Chemotherapy Protocols; Asparaginas

1994
Incidence of cataracts after single fraction total body irradiation: the role of steroids and graft versus host disease.
    Bone marrow transplantation, 1993, Volume: 12, Issue:3

    Topics: Adolescent; Adult; Bone Marrow Purging; Bone Marrow Transplantation; Cataract; Cataract Extraction;

1993
Induction of apoptosis in childhood acute leukemia by chemotherapeutic agents: failure to detect evidence of apoptosis in vivo.
    European journal of haematology, 1994, Volume: 52, Issue:1

    Topics: Adolescent; Apoptosis; Child; Child, Preschool; DNA Damage; Etoposide; Female; Humans; Leukemia, Mye

1994
Prediction of chemotherapy response in human leukemia using in vitro chemosensitivity test.
    Leukemia research, 1993, Volume: 17, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Col

1993
Changes in the oral microflora during cytotoxic chemotherapy in children being treated for acute leukemia.
    Oral surgery, oral medicine, and oral pathology, 1993, Volume: 76, Issue:2

    Topics: Adolescent; Analysis of Variance; Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Combined

1993
Late relapse after allogeneic bone marrow transplantation for Philadelphia-positive acute lymphoblastic leukaemia.
    Acta haematologica, 1993, Volume: 89, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Co

1993
[Treatment and prognosis after late relapse in childhood acute lymphoblastic leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1993, Volume: 34, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Cytarabin

1993
[Treatment of 71 adult acute lymphoblastic leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Asparagi

1993
[Treatment of adult acute lymphoblastic leukemia with DCVP-l-asp protocol].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1993, Volume: 34, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Asparagi

1993
Comparison of the antileukemic activity in vitro of dexamethasone and prednisolone in childhood acute lymphoblastic leukemia.
    Medical and pediatric oncology, 1996, Volume: 27, Issue:2

    Topics: Adolescent; Antineoplastic Agents, Hormonal; Child; Coloring Agents; Dexamethasone; Drug Screening A

1996
True histiocytic lymphoma following therapy for lymphoblastic neoplasms.
    Blood, 1996, Jun-15, Volume: 87, Issue:12

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Neoplasms; Child; Cisplati

1996
Induction toxicity of a modified Memorial Sloan-Kettering-New York II Protocol in children with relapsed acute lymphoblastic leukemia: a single institution study.
    Medical and pediatric oncology, 1996, Volume: 27, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Cyclophosphamide; Daunorubicin;

1996
Comparative cytotoxicity of dexamethasone and prednisolone in childhood acute lymphoblastic leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1996, Volume: 14, Issue:8

    Topics: Adolescent; Antineoplastic Agents, Hormonal; Apoptosis; Bone Marrow Cells; Burkitt Lymphoma; Child;

1996
Minor changes on cranial MRI during treatment in children with acute lymphoblastic leukaemia.
    Neuroradiology, 1996, Volume: 38, Issue:3

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Brain; Child; Child, Presc

1996
Donor leukocyte transfusions and discontinuation of immunosuppressants to achieve an initial remission after allogeneic bone marrow transplantation in a patient with primary refractory acute leukemia.
    Bone marrow transplantation, 1996, Volume: 18, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Clo

1996
Biological and clinical significance of in vitro prednisolone resistance in adult acute lymphoblastic leukaemia.
    European journal of haematology, 1996, Volume: 57, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Proto

1996
Lenńox-Gastaut syndrome associated with leukoencephalopathy.
    Pediatric neurology, 1996, Volume: 15, Issue:1

    Topics: Adolescent; Anticonvulsants; Antineoplastic Combined Chemotherapy Protocols; Brain Damage, Chronic;

1996
Acute lymphoblastic leukemia in Ehlers-Danlos syndrome.
    International journal of hematology, 1996, Volume: 64, Issue:3-4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child, Preschool; Cytarabine; Disease-

1996
[A case of cerebral aspergillosis associated with induction chemotherapy for acute lymphoblastic leukemia].
    No to shinkei = Brain and nerve, 1996, Volume: 48, Issue:11

    Topics: Amphotericin B; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Asp

1996
Testicular morphological changes in children with acute lymphoblastic leukemia following chemotherapy.
    Acta paediatrica Japonica : Overseas edition, 1996, Volume: 38, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy; Child; Child, Preschool; Cyclophosphamide; D

1996
[Complete remission achieved by L-asparaginase, vincristine and prednisolone (LVP) therapy in secondary leukemia (M5a type) with an MLL gene rearrangement].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1997, Volume: 38, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Co

1997
Successful treatment of steroid-resistant severe acute GVHD with 24-h continuous infusion of FK506.
    Bone marrow transplantation, 1997, Volume: 19, Issue:6

    Topics: Acute Disease; Adolescent; Bone Marrow Transplantation; Child; Drug Resistance; Female; Graft vs Hos

1997
In vitro drug sensitivity testing can predict induction failure and early relapse of childhood acute lymphoblastic leukemia.
    Blood, 1997, Apr-15, Volume: 89, Issue:8

    Topics: Aclarubicin; Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aspa

1997
A new strategy for treating patients with CD7+, CD4-, CD8- acute lymphoblastic leukaemia.
    European journal of haematology, 1997, Volume: 58, Issue:2

    Topics: Aged; Antigens, CD; Antigens, CD7; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; CD4

1997
Systemic effect of intrathecal methotrexate during the initial phase of treatment of childhood acute lymphoblastic leukemia. The European Organization for Research and Treatment of Cancer Children's Leukemia Cooperative Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:5

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Blast Crisis; Cell Count; Child; C

1997
In vitro cellular drug resistance and prognosis in newly diagnosed childhood acute lymphoblastic leukemia.
    Blood, 1997, Oct-01, Volume: 90, Issue:7

    Topics: Adolescent; Aneuploidy; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aspar

1997
Acute lymphoblastic leukemia with isolated adrenocorticotropic hormone deficiency.
    Internal medicine (Tokyo, Japan), 1997, Volume: 36, Issue:11

    Topics: Adrenocorticotropic Hormone; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Fatal Outc

1997
[Retrospective analysis of elderly patients > or = 60 years of age with acute leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1998, Volume: 39, Issue:3

    Topics: Aclarubicin; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Dau

1998
Prednisolone resistance in childhood acute lymphoblastic leukemia: vitro-vivo correlations and cross-resistance to other drugs.
    Blood, 1998, Jul-01, Volume: 92, Issue:1

    Topics: Adolescent; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Child; Child, Preschool; Drug Re

1998
Reduced energy expenditure in preobese children treated for acute lymphoblastic leukemia.
    Pediatric research, 1998, Volume: 44, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Body Mass Index; Child; Energy Metabolism; Fe

1998
Outcomes and prognostic factors of Chinese children with acute lymphoblastic leukemia in Hong Kong: preliminary results.
    Medical and pediatric oncology, 1999, Volume: 32, Issue:2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asian People; Asparaginase; Child; Child

1999
Effects of interleukin 3, interleukin 7, and B-cell growth factor on proliferation and drug resistance in vitro in childhood acute lymphoblastic leukemia.
    Annals of hematology, 1999, Volume: 78, Issue:4

    Topics: Cell Count; Cell Transformation, Neoplastic; Child; Child, Preschool; Cytarabine; Drug Resistance, N

1999
BCL-2 expression in childhood leukemia versus spontaneous apoptosis, drug induced apoptosis, and in vitro drug resistance.
    Advances in experimental medicine and biology, 1999, Volume: 457

    Topics: Apoptosis; Bone Marrow Cells; Cells, Cultured; Child; Cytarabine; Dexamethasone; Drug Resistance, Mu

1999
Differential antileukemic activity of prednisolone and dexamethasone in freshly isolated leukemic cells.
    Advances in experimental medicine and biology, 1999, Volume: 457

    Topics: Adolescent; Antineoplastic Agents; Blast Crisis; Bone Marrow; Cell Line; Child; Dexamethasone; Drug

1999
Lack of cross-resistance between prednisolone and methotrexate in childhood acute lymphoblastic leukemia? A preliminary analysis.
    Advances in experimental medicine and biology, 1999, Volume: 457

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Child; Cryopreservation; Drug Resi

1999
[Acute leukemia in Jehovah's Witnesses].
    Sangre, 1999, Volume: 44, Issue:5

    Topics: Adult; Anemia; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Blood Transfusion; Chri

1999
Biological characteristics and prognostic value of in vitro three-drug resistance to prednisolone, L-asparaginase, and vincristine in childhood acute lymphoblastic leukemia.
    International journal of hematology, 1999, Volume: 70, Issue:4

    Topics: Adolescent; Asparaginase; Bone Marrow Cells; Cell Culture Techniques; Child; Child, Preschool; Drug

1999
Role of BCL-2 and cell cycle regulatory proteins for corticosensitivity assessment in childhood acute lymphoblastic leukaemia.
    British journal of haematology, 2000, Volume: 109, Issue:1

    Topics: Adolescent; Biomarkers; Cell Division; Child; Child, Preschool; Chromosomes, Human, Pair 11; Chromos

2000
Constitutive expression levels of CD95 and Bcl-2 as well as CD95 function and spontaneous apoptosis in vitro do not predict the response to induction chemotherapy and relapse rate in childhood acute lymphoblastic leukaemia.
    British journal of haematology, 2000, Volume: 110, Issue:1

    Topics: Antineoplastic Agents, Hormonal; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1;

2000
In vitro drug resistance profiles of adult versus childhood acute lymphoblastic leukaemia.
    British journal of haematology, 2000, Volume: 110, Issue:4

    Topics: Adolescent; Adult; Age Factors; Antineoplastic Agents; Asparaginase; Bone Marrow Cells; Child; Child

2000
[Severe hemolysis and SIADH-like symptoms induced by vincristine in an ALL patient with liver cirrhosis].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2000, Volume: 41, Issue:11

    Topics: Adolescent; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Aspar

2000
Early onset Pneumocystis carinii pneumonia after allogeneic peripheral blood stem cell transplantation.
    American journal of hematology, 2001, Volume: 67, Issue:3

    Topics: Antibiotic Prophylaxis; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Combined Modal

2001
Delay of the diagnostic lumbar puncture and intrathecal chemotherapy in children with acute lymphoblastic leukemia who undergo routine corticosteroid testing: Tokyo Children's Cancer Study Group study L89-12.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001, Jul-01, Volume: 19, Issue:13

    Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; Disease-Free Survival; Drug Sc

2001
Post-induction residual leukemia in childhood acute lymphoblastic leukemia quantified by PCR correlates with in vitro prednisolone resistance.
    Leukemia, 2001, Volume: 15, Issue:7

    Topics: Adolescent; Child; Child, Preschool; Drug Resistance, Neoplasm; Humans; Infant; Neoplasm, Residual;

2001
Repetitious appearance and disappearance of different kinds of clonal cytogenetic abnormalities after allogeneic bone marrow transplantation.
    International journal of hematology, 2001, Volume: 74, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Child, Pr

2001
Prognostic impact of CD45 antigen expression in high-risk, childhood B-cell precursor acute lymphoblastic leukemia.
    Leukemia & lymphoma, 2001, Volume: 42, Issue:3

    Topics: Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; B-Lymphocytes; Child; Di

2001
Different drug sensitivity profiles of acute myeloid and lymphoblastic leukemia and normal peripheral blood mononuclear cells in children with and without Down syndrome.
    Blood, 2002, Jan-01, Volume: 99, Issue:1

    Topics: Amsacrine; Anthracyclines; Antineoplastic Agents; Busulfan; Cell Survival; Child; Child, Preschool;

2002
Adult lymphoblastic lymphoma in Taiwan: an analysis of treatment results of 26 patients.
    Annals of hematology, 2001, Volume: 80, Issue:11

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow T

2001
In vitro drug resistance profile of Philadelphia positive acute lymphoblastic leukemia is heterogeneous and related to age: a report of the Dutch and German Leukemia Study Groups.
    Medical and pediatric oncology, 2002, Volume: 38, Issue:6

    Topics: Adult; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Child; Drug R

2002
Acute lymphocytic leukemia CNS disease presenting as central diabetes insipidus.
    The Journal of the Association of Physicians of India, 2002, Volume: 50

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain; Chlorambucil; Deamino Arginine Vasopre

2002
Bone marrow examination before steroids in thrombocytopenic purpura or arthritis.
    Acta paediatrica (Oslo, Norway : 1992), 1992, Volume: 81, Issue:12

    Topics: Arthritis, Juvenile; Bone Marrow Examination; Child; Diagnosis, Differential; Female; Humans; Infant

1992
[Treatment of elderly patients with hematological malignancies].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:11

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modalit

1992
Etoposide, ifosfamide, and methotrexate combination chemotherapy for aggressive non-Hodgkin's lymphomas after failure of the LNH 84 regimen.
    Seminars in oncology, 1992, Volume: 19, Issue:1 Suppl 1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow; Cyclophosphamid

1992
[The programmed therapy of acute lymphoblastic leukemia in adults].
    Terapevticheskii arkhiv, 1992, Volume: 64, Issue:8

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow; Cyclop

1992
Acute lymphoblastic leukaemia presenting as breast mass.
    The Journal of the Association of Physicians of India, 1992, Volume: 40, Issue:5

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Doxorubicin; Female; H

1992
[Evaluation of 58 patients with acute leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administ

1992
Cellular kinetics of prednimustine versus chlorambucil plus prednisolone in vitro.
    Cancer chemotherapy and pharmacology, 1992, Volume: 29, Issue:4

    Topics: Animals; Carcinoma; Chlorambucil; Chromatography, High Pressure Liquid; Colonic Neoplasms; Mammary N

1992
Long-term survival in acute lymphoblastic leukaemia in adults: a prospective study of 51 patients. Finnish Leukaemia Group.
    European journal of haematology, 1992, Volume: 48, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Doxorubicin; Female

1992
Four-agent induction/consolidation therapy for childhood acute lymphoblastic leukemia: an Indian experience.
    American journal of hematology, 1992, Volume: 39, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Doxorubicin; Fe

1992
[Acute lymphocytic leukemia (L1) preceded by hypercalcemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1992, Volume: 33, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Calcitonin; Female; Humans; Hypercalcemia; Pr

1992
Relation of cellular drug resistance to long-term clinical outcome in childhood acute lymphoblastic leukaemia.
    Lancet (London, England), 1991, Aug-17, Volume: 338, Issue:8764

    Topics: Antineoplastic Agents; Asparaginase; Chi-Square Distribution; Child; Coloring Agents; Daunorubicin;

1991
[A study of combination chemotherapy (BHAC-ACVP) for adult acute lymphocytic leukemia. Hanshin Co-operative Study Group of Hematological Malignancies].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Admi

1992
Prognostic factors and outcome of therapy in adult acute lymphoblastic leukemia.
    Indian journal of cancer, 1991, Volume: 28, Issue:3

    Topics: Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Child; Doxorubicin;

1991
[The results of using differentiated programs of therapy in acute lymphoblastic leukemia in adults].
    Terapevticheskii arkhiv, 1991, Volume: 63, Issue:7

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Female; Human

1991
Decrease in number of CD16(Leu 11)+CD45RA(2H4)+ cells and defective production of natural killer cytotoxic factor in childhood acute lymphoblastic leukemia.
    Leukemia research, 1991, Volume: 15, Issue:9

    Topics: Adult; Antigens, CD; Antigens, Differentiation; Antineoplastic Combined Chemotherapy Protocols; Aspa

1991
[Metabolic disorders in the treatment of malignant hematologic diseases--the acute tumor lysis syndrome].
    Ugeskrift for laeger, 1991, Oct-14, Volume: 153, Issue:42

    Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin;

1991
[Treatment of adult acute lymphoblastic leukemia with Ad-VP-L regimen].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1991, Volume: 32, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Doxorubicin;

1991
A longitudinal study of growth and growth hormone secretion in children during treatment for acute lymphoblastic leukemia.
    Medical and pediatric oncology, 1991, Volume: 19, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Body Height; Body Weight; Child; Child, Preschool; C

1991
[Treatment of children with acute lymphoblastic leukemia].
    Gematologiia i transfuziologiia, 1991, Volume: 36, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Ch

1991
[Effects of immunosuppressive chemotherapy on serum levels of IgG subclasses--analysis in children with acute lymphoblastic leukemia and in children with aplastic anemia and autoimmune diseases receiving corticosteroid hormone].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1990, Volume: 31, Issue:12

    Topics: Anemia, Aplastic; Autoimmune Diseases; Child; Child, Preschool; Humans; Immunoglobulin G; Immunosupp

1990
High dose cytosine arabinoside in the initial treatment of adults with acute lymphoblastic leukaemia.
    British journal of cancer, 1990, Volume: 62, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cyclophosphamide; C

1990
An animal model to study toxicity of central nervous system therapy for childhood acute lymphoblastic leukemia: effects on growth and craniofacial proportion.
    Cancer research, 1990, Oct-15, Volume: 50, Issue:20

    Topics: Animals; Cephalometry; Combined Modality Therapy; Female; Growth; Humans; Male; Methotrexate; Precur

1990
An animal model to study toxicity of central nervous system therapy for childhood acute lymphoblastic leukemia: effects on behavior.
    Cancer research, 1990, Oct-15, Volume: 50, Issue:20

    Topics: Animals; Behavior, Animal; Brain; Cognition Disorders; Combined Modality Therapy; Female; Humans; Ma

1990
Successful treatment of acute leukemia with t(4;11) in an infant with congenital hypothyroidism.
    The American journal of pediatric hematology/oncology, 1990,Fall, Volume: 12, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Differentiation; Chromosomes, Human, Pair 11; C

1990
[Transient dysfibrinogenemia and cerebral thrombosis following remission induction therapy for acute lymphoblastic leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1990, Volume: 31, Issue:9

    Topics: Adult; Afibrinogenemia; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubici

1990
Cell membrane fluidity in blast cells of children with acute leukaemia.
    Acta paediatrica Hungarica, 1990, Volume: 30, Issue:2

    Topics: Acute Disease; Blast Crisis; Bone Marrow; Child; Diphenylhexatriene; Fluorescence Polarization; Huma

1990
In vitro drug sensitivity of cells from children with leukemia using the MTT assay with improved culture conditions.
    Blood, 1990, Dec-01, Volume: 76, Issue:11

    Topics: Asparaginase; Cells, Cultured; Child; Coloring Agents; Culture Media; Cyclophosphamide; Cytarabine;

1990
[Nursing care of leukemia patients in cytolysis syndrome by chemotherapy].
    Zhonghua hu li za zhi = Chinese journal of nursing, 1990, Volume: 25, Issue:12

    Topics: Acute Kidney Injury; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Female; Huma

1990
The role of azathioprine in the management of ulcerative colitis.
    Diseases of the colon and rectum, 1990, Volume: 33, Issue:5

    Topics: Adult; Azathioprine; Colitis, Ulcerative; Female; Humans; Leukopenia; Lymphoma, Non-Hodgkin; Male; M

1990
Intestinal obstruction at the onset of acute lymphoblastic leukemia in a child.
    The American journal of pediatric hematology/oncology, 1990,Summer, Volume: 12, Issue:2

    Topics: Abdomen, Acute; Antineoplastic Combined Chemotherapy Protocols; Blood Transfusion; Child, Preschool;

1990
[Long-term surviving child with acute lymphoblastic leukemia complicated with legionellosis].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1990, Volume: 31, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Female; Follow-Up Studies; Humans; Legionnair

1990
[Multi-agent combination chemotherapy for adult acute lymphoblastic leukemia--individualized chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:9

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosph

1990
[Treatment of acute lymphocytic leukemia in adult].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1989, Volume: 30, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Daunorubicin;

1989
Pharmacokinetics of prednisolone in children with acute lymphoblastic leukaemia.
    Cancer chemotherapy and pharmacology, 1989, Volume: 23, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Female; Half-Life; Humans;

1989
Acute lymphoblastic leukemia in Chinese adults in Hong Kong.
    Australian and New Zealand journal of medicine, 1989, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; China;

1989
Prevention of urate nephropathy in the tumour lysis syndrome.
    Clinical and laboratory haematology, 1989, Volume: 11, Issue:2

    Topics: Adolescent; Allopurinol; Antineoplastic Combined Chemotherapy Protocols; Daunorubicin; Diuresis; Hum

1989
Disturbed pubertal growth in girls treated for acute lymphoblastic leukemia.
    Pediatric hematology and oncology, 1987, Volume: 4, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Body Height; Child; Child, Preschool; Co

1987
Prognosis after relapse in acute lymphoblastic leukemia in childhood.
    Pediatric hematology and oncology, 1986, Volume: 3, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cranial Irradiation; Doxo

1986
[BH-AC.AMP protocol in the treatment of refractory childhood acute leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:10

    Topics: Aclarubicin; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cy

1988
Aggressive treatment improves survival in adult acute lymphoblastic leukemia.
    European journal of haematology, 1988, Volume: 41, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Blood Transfusion;

1988
Treatment of high-risk acute lymphoblastic leukemia with protocols PETHEMA LAL 7/78 and LAL 17/84.
    Anales espanoles de pediatria, 1988, Volume: 29 Suppl 34

    Topics: Adolescent; Antineoplastic Agents; Asparaginase; Child; Child, Preschool; Clinical Protocols; Cytara

1988
[L-asparaginase therapy against hybrid leukemia: a case report].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1988, Volume: 29, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Doxorubicin; Humans; Leukemia, Myeloid

1988
[The action of antitumor preparations on the rosette-forming function of lymphocytes].
    Gematologiia i transfuziologiia, 1988, Volume: 33, Issue:8

    Topics: Antineoplastic Agents; Depression, Chemical; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute;

1988