Page last updated: 2024-11-06

prednisolone and Abortion, Spontaneous

prednisolone has been researched along with Abortion, Spontaneous in 24 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Abortion, Spontaneous: Expulsion of the product of FERTILIZATION before completing the term of GESTATION and without deliberate interference.

Research Excerpts

ExcerptRelevanceReference
"The objective of this study was to assess pregnancy outcome in women with a history of refractory antiphospholipid antibody-associated pregnancy loss(es) who were treated with early low-dose prednisolone in addition to aspirin and heparin."7.77First-trimester low-dose prednisolone in refractory antiphospholipid antibody-related pregnancy loss. ( Bramham, K; Hunt, BJ; Khamashta, M; Nelson-Piercy, C; Thomas, M, 2011)
"Through a non-randomized clinical trial, we examined the theoretical benefit of the coadministration of low molecular weight heparin (LMWH) and prednisolone on pregnancy outcomes in women with previously failed IVF/ICSI cycles."5.17Addition of prednisolone and heparin in patients with failed IVF/ICSI cycles: a preliminary report of a clinical trial. ( Chrelias, C; Creatsa, M; Iliodromiti, Z; Kassanos, D; Siristatidis, C; Varounis, C; Vrachnis, N, 2013)
"The objective of this study was to assess pregnancy outcome in women with a history of refractory antiphospholipid antibody-associated pregnancy loss(es) who were treated with early low-dose prednisolone in addition to aspirin and heparin."3.77First-trimester low-dose prednisolone in refractory antiphospholipid antibody-related pregnancy loss. ( Bramham, K; Hunt, BJ; Khamashta, M; Nelson-Piercy, C; Thomas, M, 2011)
"Positive b-hCG, miscarriage, and live birth rates were similar between groups as Group A vs."1.91Low Molecular Weight Heparin-Aspirin-Prednisolone Combination Does Not Increase the Live Birth Rate in Recurrent Implantation Failure: A Retrospective Cohort Study. ( Aslan, K; Avci, B; Cakir, C; Cinar, C; Kasapoglu, I; Uncu, G, 2023)
"Prednisolone was found to improve the rate of live births, although it was also a predictor of prematurity."1.36Pregnancy outcome in 396 pregnancies in patients with SLE in Saudi Arabia. ( Al Arfaj, AS; Khalil, N, 2010)
"Her pregnancy was managed with anticoagulant therapy and she delivered a healthy infant."1.32Graves' disease associated with anticardiolipin antibody positivity and acquired protein S deficiency. ( Kanmatsuse, K; Kokubun, S; Nakayama, T; Yamamoto, T, 2003)
"The association of Wegener's granulomatosis and pregnancy is rare and poses unique therapeutic challenges, particularly when active disease presents in early pregnancy."1.30Relapse of Wegener's granulomatosis in the first trimester of pregnancy: a case report. ( Garg, OP; Gupta, R; Kumar, A; Mohan, A; Singal, VK, 1998)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19908 (33.33)18.7374
1990's5 (20.83)18.2507
2000's2 (8.33)29.6817
2010's7 (29.17)24.3611
2020's2 (8.33)2.80

Authors

AuthorsStudies
Moar, L1
Simela, C1
Nanda, S1
Marnerides, A1
Al-Adnani, M1
Nelson-Piercy, C2
Nicolaides, KH1
Shangaris, P1
Aslan, K1
Kasapoglu, I1
Cinar, C1
Cakir, C1
Avci, B1
Uncu, G1
Tang, AW1
Alfirevic, Z1
Turner, MA1
Drury, JA1
Small, R1
Quenby, S1
Siristatidis, C1
Chrelias, C1
Creatsa, M1
Varounis, C1
Vrachnis, N1
Iliodromiti, Z1
Kassanos, D1
Lynch, E1
Shetty, S1
Ghosh, K1
Falhammar, H1
Al Arfaj, AS1
Khalil, N1
Bramham, K1
Thomas, M1
Khamashta, M1
Hunt, BJ1
Krigstein, M1
Sacks, G1
Nakayama, T1
Yamamoto, T1
Kanmatsuse, K1
Kokubun, S1
BORKA, I1
TambyRaja, RL1
Yagami, Y1
Murphy, MF1
Hambley, H1
Nicolaides, K1
Waters, AH1
Kumar, A1
Mohan, A1
Gupta, R1
Singal, VK1
Garg, OP1
Kofteridis, DP1
Malliotakis, PI1
Sotsiou, F1
Vardakis, NK1
Vamvakas, LN1
Emmanouel, DS1
Steven, MM1
Buckley, JD1
Mackay, IR1
Lamotte, M1
Segrestaa, JM1
Galian, A1
Kaplan, S1
Tóth, B1
Fülöp, E1
Simon, J1
Ewing, PA1
Whittaker, JA1
Stojanov, S1
Eyton-Jones, J1
Roberti, D1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Low Dose Prednisone Therapy in Women With Recurrent Pregnancy Loss[NCT04558268]Phase 2/Phase 3242 participants (Anticipated)Interventional2020-12-31Not yet recruiting
The Lupus prEGnAnCY Cohort: An International Prospective Cohort of Lupus Pregnancies[NCT03746028]100 participants (Anticipated)Observational [Patient Registry]2018-06-06Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for prednisolone and Abortion, Spontaneous

ArticleYear
Chronic histiocytic intervillositis (CHI): current treatments and perinatal outcomes, a systematic review and a meta-analysis.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Abortion, Spontaneous; Adalimumab; Aspirin; Female; Heparin, Low-Molecular-Weight; Humans; Hydroxych

2022
Anti-phospholipid antibodies and other immunological causes of recurrent foetal loss--a review of literature of various therapeutic protocols.
    American journal of reproductive immunology (New York, N.Y. : 1989), 2009, Volume: 62, Issue:1

    Topics: Abortion, Spontaneous; Anti-Inflammatory Agents; Antibodies, Antiphospholipid; Aspirin; Clinical Tri

2009
Prednisolone for repeated implantation failure associated with high natural killer cell levels.
    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2012, Volume: 32, Issue:6

    Topics: Abortion, Spontaneous; Adult; Anti-Inflammatory Agents; Embryo Implantation; Female; Humans; Killer

2012
[Pathogenesis on infertility; its immunological aspects].
    Nihon Sanka Fujinka Gakkai zasshi, 1993, Volume: 45, Issue:8

    Topics: Abortion, Spontaneous; Antibodies, Antiphospholipid; Aspirin; Autoimmune Diseases; Cytokines; Female

1993

Trials

2 trials available for prednisolone and Abortion, Spontaneous

ArticleYear
A feasibility trial of screening women with idiopathic recurrent miscarriage for high uterine natural killer cell density and randomizing to prednisolone or placebo when pregnant.
    Human reproduction (Oxford, England), 2013, Volume: 28, Issue:7

    Topics: Abortion, Habitual; Abortion, Spontaneous; Adult; Feasibility Studies; Female; Glucocorticoids; Huma

2013
Addition of prednisolone and heparin in patients with failed IVF/ICSI cycles: a preliminary report of a clinical trial.
    Human fertility (Cambridge, England), 2013, Volume: 16, Issue:3

    Topics: Abortion, Spontaneous; Administration, Intravaginal; Administration, Oral; Adult; Anticoagulants; Ea

2013

Other Studies

18 other studies available for prednisolone and Abortion, Spontaneous

ArticleYear
Low Molecular Weight Heparin-Aspirin-Prednisolone Combination Does Not Increase the Live Birth Rate in Recurrent Implantation Failure: A Retrospective Cohort Study.
    Reproductive sciences (Thousand Oaks, Calif.), 2023, Volume: 30, Issue:11

    Topics: Abortion, Spontaneous; Aspirin; Birth Rate; Female; Fertilization in Vitro; Heparin, Low-Molecular-W

2023
Natural born killer.
    Midwives, 2014, Volume: 17, Issue:1

    Topics: Abortion, Habitual; Abortion, Spontaneous; Female; Glucocorticoids; Humans; Immunotherapy; Killer Ce

2014
Non-classic congenital adrenal hyperplasia due to 21-hydoxylase deficiency as a cause of infertility and miscarriages.
    The New Zealand medical journal, 2010, Apr-09, Volume: 123, Issue:1312

    Topics: Abortion, Spontaneous; Adrenal Hyperplasia, Congenital; Adult; Female; Glucocorticoids; Humans; Infe

2010
Pregnancy outcome in 396 pregnancies in patients with SLE in Saudi Arabia.
    Lupus, 2010, Volume: 19, Issue:14

    Topics: Abortion, Spontaneous; Adolescent; Adult; Antibodies, Antiphospholipid; Female; Glucocorticoids; Hum

2010
First-trimester low-dose prednisolone in refractory antiphospholipid antibody-related pregnancy loss.
    Blood, 2011, Jun-23, Volume: 117, Issue:25

    Topics: Abortion, Spontaneous; Adult; Anti-Inflammatory Agents; Antibodies, Antiphospholipid; Anticoagulants

2011
Graves' disease associated with anticardiolipin antibody positivity and acquired protein S deficiency.
    Rheumatology international, 2003, Volume: 23, Issue:4

    Topics: Abortion, Spontaneous; Adult; Anti-Inflammatory Agents; Antibodies, Anticardiolipin; Anticoagulants;

2003
[SHEEHAN'S SYNDROME FOLLOWING ABORTION].
    Orvosi hetilap, 1965, Apr-04, Volume: 106

    Topics: Abortion, Induced; Abortion, Spontaneous; Drug Therapy; Female; Humans; Hypopituitarism; Organothera

1965
Fetal salvage in maternal systemic lupus erythematosus.
    Annals of the Academy of Medicine, Singapore, 1993, Volume: 22, Issue:4

    Topics: Abortion, Spontaneous; Adult; Azathioprine; Female; Fetal Death; Humans; Infant, Newborn; Kidney Fun

1993
Severe fetomaternal alloimmune thrombocytopenia presenting with fetal hydrocephalus.
    Prenatal diagnosis, 1996, Volume: 16, Issue:12

    Topics: Abortion, Habitual; Abortion, Spontaneous; Anemia; Antigens, Human Platelet; Female; Fetal Diseases;

1996
Relapse of Wegener's granulomatosis in the first trimester of pregnancy: a case report.
    British journal of rheumatology, 1998, Volume: 37, Issue:3

    Topics: Abortion, Spontaneous; Adult; Anti-Inflammatory Agents; Female; Granulomatosis with Polyangiitis; Hu

1998
Acute onset of dermatomyositis presenting in pregnancy with rhabdomyolysis and fetal loss.
    Scandinavian journal of rheumatology, 1999, Volume: 28, Issue:3

    Topics: Abortion, Spontaneous; Adult; Biopsy; Dermatomyositis; Diagnosis, Differential; Female; Fetal Death;

1999
Pregnancy in chronic active hepatitis.
    The Quarterly journal of medicine, 1979, Volume: 48, Issue:192

    Topics: Abortion, Spontaneous; Adolescent; Adult; Autoimmune Diseases; Chronic Disease; Female; Fertility; F

1979
[Current evolutive forms of typhoid fever. Apropos of 2 cases].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1966, Oct-08, Volume: 42, Issue:41

    Topics: Abortion, Spontaneous; Adult; Chloramphenicol; Encephalitis; Female; Humans; Hydrocortisone; Male; M

1966
[The mutual effects of scleroderma diffusum and pregnancy].
    Zentralblatt fur Gynakologie, 1969, Apr-19, Volume: 91, Issue:16

    Topics: Abortion, Spontaneous; Adrenocorticotropic Hormone; Adult; Female; Humans; Prednisolone; Pregnancy;

1969
Acute leukemia in pregnancy.
    Obstetrics and gynecology, 1973, Volume: 42, Issue:2

    Topics: Abortion, Spontaneous; Abortion, Therapeutic; Adult; Blood Coagulation Tests; Blood Platelets; Blood

1973
[Adrenogenital syndrome and pregnancy].
    Zentralblatt fur Gynakologie, 1973, Sep-28, Volume: 95, Issue:39

    Topics: Abortion, Spontaneous; Adrenal Hyperplasia, Congenital; Adult; Berlin; Cesarean Section; Female; Fer

1973
The adrenogenital syndrome and pregnancy.
    The Journal of obstetrics and gynaecology of the British Commonwealth, 1968, Volume: 75, Issue:10

    Topics: Abortion, Spontaneous; Adrenal Hyperplasia, Congenital; Adult; Cortisone; Female; Humans; Prednisolo

1968
[Action of prednisolone and alpha-tocopherol on the course and outcome of pregnancy in a strain of albino mice].
    Bollettino della Societa italiana di biologia sperimentale, 1965, Jun-15, Volume: 41, Issue:11

    Topics: Abortion, Spontaneous; Animals; Birth Weight; Female; Fetus; Mice; Prednisolone; Pregnancy; Pregnanc

1965