prednisolone has been researched along with Abortion, Recurrent in 38 studies
Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This retrospective study of prospectively collected data examines the effect of prednisolone therapy on raised uterine Natural Killer cell (uNK) concentrations and pregnancy outcomes in women with recurrent miscarriage (RM) and recurrent implantation failure (RIF) after IVF/ICSI treatment." | 7.91 | The effect of prednisolone on endometrial uterine NK cell concentrations and pregnancy outcome in women with reproductive failure. A retrospective cohort study. ( Cooper, S; Laird, SM; Li, TC; Mariee, N; Metwally, M, 2019) |
| "Prednisolone or IVIG was then added to the tube with E:T ratio of 50:1 to assess suppressive effect." | 5.35 | Prednisolone suppresses NK cell cytotoxicity in vitro in women with a history of infertility and elevated NK cell cytotoxicity. ( Abdalla, HI; Bansal, A; Bhaskaran, S; Ford, B; Sumar, N; Thum, MY, 2008) |
| "We did a statistical analysis and found that oral immunosuppressants (including cyclosporine A or prednisolone) can improve pregnancy outcomes in patients with idiopathic RM, increase live birth rate and ongoing pregnancy rate, and reduce miscarriage rate." | 5.22 | Oral immunosuppressants improve pregnancy outcomes in women with idiopathic recurrent miscarriage: A meta-analysis. ( Hang, F; Liao, M; Ma, N; Qin, A; Qin, R; Qin, W; Zhao, Y, 2022) |
| "The effects of prednisolone on pregnancy outcome are open to debate." | 4.91 | Effect of Prednisolone Administration on Patients with Unexplained Recurrent Miscarriage and in Routine Intracytoplasmic Sperm Injection: A Meta-Analysis. ( Dan, S; Hong, L; Hongbo, C; Jiaxiong, W; Shenmin, Y; Wei, W; Yichao, S, 2015) |
| "This retrospective study of prospectively collected data examines the effect of prednisolone therapy on raised uterine Natural Killer cell (uNK) concentrations and pregnancy outcomes in women with recurrent miscarriage (RM) and recurrent implantation failure (RIF) after IVF/ICSI treatment." | 3.91 | The effect of prednisolone on endometrial uterine NK cell concentrations and pregnancy outcome in women with reproductive failure. A retrospective cohort study. ( Cooper, S; Laird, SM; Li, TC; Mariee, N; Metwally, M, 2019) |
| "We treated four pregnancy cases positive for antiphospholipid antibodies (APLs) who had experienced recurrent second trimester fetal or neonatal losses using a Japanese modified Chinese herbal medicine, Sairei-to, low dose aspirin and adrenocorticosteroid hormone." | 3.72 | Effect of sairei-to combined with aspirin and prednisolone on four recurrent reproductive failure women who are positive for anti-phospholipid antibodies. ( Adachi, H; Ishii, K; Kurabayasi, T; Kurata, H; Natsume, N; Takaki, Y; Takakuwa, K; Tamura, M; Tanaka, K, 2003) |
| " The question of whether anti-GM3 antibodies might exert influence in APLs-positive recurrent pregnancy loss patients who are undergoing prednisolone and aspirin (PSL/ASA) treatment was investigated." | 3.69 | Clinical significance of anti-GM3 antibodies in recurrent pregnancy loss with elevated level of antiphospholipid antibodies. ( Aoki, K; Aoyama, T; Kunimatsu, M; Ozaki, Y, 1995) |
| "Idiopathic recurrent miscarriage is defined as 3 consecutive pregnancy losses with no contributing features found on investigations." | 2.74 | Prednisolone Trial: Study protocol for a randomised controlled trial of prednisolone for women with idiopathic recurrent miscarriage and raised levels of uterine natural killer (uNK) cells in the endometrium. ( Alfirevic, Z; Drury, J; Quenby, S; Tang, AW; Turner, MA, 2009) |
| "Pregnancy was successfully carried out in 12/12 (100%) SLE-RSA patients with a mean Apgar score of 8." | 2.73 | Intravenous immunoglobulin therapy in pregnant patients affected with systemic lupus erythematosus and recurrent spontaneous abortion. ( Cipriani, P; De Carolis, C; Fontana, L; Giacomelli, R; Greco, E; Kröegler, B; Perricone, C; Perricone, R, 2008) |
| "Prednisolone treatment reduces endometrial vascular maturation and angiogenic growth factor expression in women with RM with increased uNK cells." | 1.37 | Prednisolone treatment reduces endometrial spiral artery development in women with recurrent miscarriage. ( Bulmer, JN; Drury, JA; Innes, BA; Lash, GE; Quenby, S; Robson, SC, 2011) |
| "Prednisolone or IVIG was then added to the tube with E:T ratio of 50:1 to assess suppressive effect." | 1.35 | Prednisolone suppresses NK cell cytotoxicity in vitro in women with a history of infertility and elevated NK cell cytotoxicity. ( Abdalla, HI; Bansal, A; Bhaskaran, S; Ford, B; Sumar, N; Thum, MY, 2008) |
| "Prednisolone treatment significantly reduced the number of CD56 cells in the endometrium, from a median of 14% (before) to 9% (after) (P=." | 1.33 | Prednisolone reduces preconceptual endometrial natural killer cells in women with recurrent miscarriage. ( Bates, M; Farquharson, R; Kalumbi, C; Quenby, S; Vince, G, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (18.42) | 18.7374 |
| 1990's | 11 (28.95) | 18.2507 |
| 2000's | 8 (21.05) | 29.6817 |
| 2010's | 9 (23.68) | 24.3611 |
| 2020's | 3 (7.89) | 2.80 |
| Authors | Studies |
|---|---|
| Ma, N | 1 |
| Qin, R | 1 |
| Qin, W | 1 |
| Liao, M | 1 |
| Zhao, Y | 1 |
| Hang, F | 1 |
| Qin, A | 1 |
| Nørgaard-Pedersen, C | 1 |
| Nielsen, K | 1 |
| Steffensen, R | 1 |
| Eriksen, L | 1 |
| Jørgensen, MM | 1 |
| Kesmodel, US | 1 |
| Christiansen, OB | 1 |
| Woon, EV | 1 |
| Day, A | 1 |
| Bracewell-Milnes, T | 1 |
| Male, V | 1 |
| Johnson, M | 1 |
| Sasaki, A | 1 |
| Kuroda, K | 1 |
| Hisano, M | 1 |
| Ozawa, N | 2 |
| Sago, H | 1 |
| Yamaguchi, K | 1 |
| Deguchi, M | 1 |
| Maesawa, Y | 1 |
| Kubota, S | 1 |
| Morizane, M | 1 |
| Tanimura, K | 1 |
| Ebina, Y | 1 |
| Yamada, H | 1 |
| Cooper, S | 1 |
| Laird, SM | 1 |
| Mariee, N | 1 |
| Li, TC | 1 |
| Metwally, M | 1 |
| Tang, AW | 2 |
| Alfirevic, Z | 2 |
| Turner, MA | 2 |
| Drury, JA | 2 |
| Small, R | 1 |
| Quenby, S | 5 |
| Gomaa, MF | 1 |
| Elkholy, AG | 1 |
| El-Said, MM | 1 |
| Abdel-Salam, NE | 1 |
| Lynch, E | 1 |
| Dan, S | 1 |
| Wei, W | 1 |
| Yichao, S | 1 |
| Hongbo, C | 1 |
| Shenmin, Y | 1 |
| Jiaxiong, W | 1 |
| Hong, L | 1 |
| Robertson, SA | 1 |
| Jin, M | 1 |
| Yu, D | 1 |
| Moldenhauer, LM | 1 |
| Davies, MJ | 1 |
| Hull, ML | 1 |
| Norman, RJ | 1 |
| Drury, J | 1 |
| Lash, GE | 1 |
| Bulmer, JN | 1 |
| Innes, BA | 1 |
| Robson, SC | 1 |
| Takakuwa, K | 3 |
| Ishii, K | 1 |
| Takaki, Y | 1 |
| Natsume, N | 1 |
| Adachi, H | 1 |
| Kurata, H | 1 |
| Tamura, M | 2 |
| Kurabayasi, T | 1 |
| Tanaka, K | 3 |
| Farquharson, R | 2 |
| Young, M | 1 |
| Vince, G | 2 |
| Kalumbi, C | 1 |
| Bates, M | 1 |
| Carbillon, L | 1 |
| Thum, MY | 1 |
| Bhaskaran, S | 1 |
| Abdalla, HI | 1 |
| Ford, B | 1 |
| Sumar, N | 1 |
| Bansal, A | 1 |
| Perricone, R | 1 |
| De Carolis, C | 1 |
| Kröegler, B | 1 |
| Greco, E | 1 |
| Giacomelli, R | 1 |
| Cipriani, P | 1 |
| Fontana, L | 1 |
| Perricone, C | 1 |
| Hartikainen-Sorri, AL | 1 |
| Kaila, J | 1 |
| Ozaki, Y | 1 |
| Aoki, K | 4 |
| Aoyama, T | 3 |
| Kunimatsu, M | 1 |
| al-Momen, AK | 2 |
| Moghraby, SA | 1 |
| el-Rab, MO | 1 |
| Gader, AM | 1 |
| al-Balla, SR | 1 |
| al-Meshari, AA | 1 |
| al-Nuaim, L | 1 |
| Someya, K | 1 |
| Hosokawa, T | 1 |
| Nemoto, T | 1 |
| Iwasaki, S | 1 |
| Nozawa, S | 1 |
| Makino, T | 1 |
| Murphy, MF | 1 |
| Hambley, H | 1 |
| Nicolaides, K | 1 |
| Waters, AH | 1 |
| Arakawa, M | 1 |
| Honda, K | 1 |
| Imai, T | 1 |
| Kurabayashi, T | 1 |
| Katano, K | 2 |
| Ogasawara, M | 2 |
| Suzumori, K | 2 |
| Sasa, H | 1 |
| Darmochwał-Kolarz, D | 1 |
| Leszczyńska-Gorzelak, B | 1 |
| Oleszczuk, J | 1 |
| Ho, HN | 2 |
| Melinda, S | 1 |
| Lin, HH | 1 |
| Hwang, JL | 2 |
| Hsieh, CY | 2 |
| Lee, TY | 1 |
| Yoshida, A | 2 |
| Morozumi, K | 2 |
| Koyama, K | 1 |
| Fukuda, M | 1 |
| Oikawa, T | 1 |
| Hasegawa, I | 1 |
| Goto, S | 1 |
| Yamada, K | 1 |
| Sekizuka, N | 1 |
| Kanazawa, K | 1 |
| Sulimani, R | 1 |
| Harakati, M | 1 |
| Gader, AG | 1 |
| Mekki, M | 1 |
| Huang, LW | 1 |
| Shen, MC | 1 |
| Mizoguchi, K | 1 |
| Kakisako, S | 1 |
| Tanaka, M | 1 |
| Yano, H | 1 |
| Shimizu, T | 1 |
| Gondoh, Y | 1 |
| Shoji, H | 1 |
| Kaji, M | 1 |
| Gancel, A | 1 |
| Courtois, H | 1 |
| Doucet, J | 1 |
| Schrub, JC | 1 |
| Le Bouedec, G | 1 |
| Fondrinier, E | 1 |
| Sauvezie, B | 1 |
| Bruhat, MA | 1 |
| Suganuma, T | 1 |
| Shinmura, I | 1 |
| Fujinami, T | 1 |
| Yagami, Y | 1 |
| Svetlova, AK | 1 |
| Rozovskiĭ, IS | 1 |
| Stepanova, RA | 1 |
| Golovatskaya, GI | 1 |
| Tkachenko, NM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Intravenous Immunoglobulin and Prednisolone to Women With Unexplained Recurrent Pregnancy Loss After Assisted Reproductive Technology Treatment: a Randomised, Double-blind, Placebo-controlled Trial[NCT04701034] | Phase 2 | 74 participants (Anticipated) | Interventional | 2021-02-06 | Recruiting | ||
| Low Dose Prednisone Therapy in Women With Recurrent Pregnancy Loss[NCT04558268] | Phase 2/Phase 3 | 242 participants (Anticipated) | Interventional | 2020-12-31 | Not yet recruiting | ||
| A Three-arm, Multicenter, Open-label Randomized Controlled Trial of Hydroxychloroquine and Low-dose Prednisone on Recurrent Spontaneous Abortion With Undifferentiated Connective Tissue Diseases: Protocol for the Immunosuppressant Regimens for Living FEtus[NCT03671174] | 420 participants (Anticipated) | Interventional | 2019-08-02 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for prednisolone and Abortion, Recurrent
| Article | Year |
|---|---|
Oral immunosuppressants improve pregnancy outcomes in women with idiopathic recurrent miscarriage: A meta-analysis.
Topics: Abortion, Habitual; Cyclosporine; Female; Humans; Immunosuppressive Agents; Live Birth; Prednisolone | 2022 |
Immunotherapy to improve pregnancy outcome in women with abnormal natural killer cell levels/activity and recurrent miscarriage or implantation failure: A systematic review and meta-analysis.
Topics: Abortion, Habitual; Embryo Implantation; Emulsions; Etanercept; Female; Humans; Immunoglobulins, Int | 2020 |
Effect of Prednisolone Administration on Patients with Unexplained Recurrent Miscarriage and in Routine Intracytoplasmic Sperm Injection: A Meta-Analysis.
Topics: Abortion, Habitual; Embryo Implantation; Female; Humans; Killer Cells, Natural; Leukocyte Count; Liv | 2015 |
Corticosteroid therapy in assisted reproduction - immune suppression is a faulty premise.
Topics: Abortion, Habitual; Embryo Implantation; Endometrium; Female; Humans; Immunosuppressive Agents; Pred | 2016 |
6 trials available for prednisolone and Abortion, Recurrent
28 other studies available for prednisolone and Abortion, Recurrent
| Article | Year |
|---|---|
Successful treatment for a recurrent pregnancy loss woman with high Th1/Th2 ratio using medium-dose corticosteroids.
Topics: Abortion, Habitual; Adrenal Cortex Hormones; Adult; CD4 Lymphocyte Count; Female; Fetal Death; Gesta | 2017 |
Factors associated with adverse pregnancy outcomes in women with systematic lupus erythematosus.
Topics: Abortion, Habitual; Adult; Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Complement Syste | 2018 |
The effect of prednisolone on endometrial uterine NK cell concentrations and pregnancy outcome in women with reproductive failure. A retrospective cohort study.
Topics: Abortion, Habitual; Adult; Embryo Implantation; Endometrium; Female; Humans; Killer Cells, Natural; | 2019 |
Natural born killer.
Topics: Abortion, Habitual; Abortion, Spontaneous; Female; Glucocorticoids; Humans; Immunotherapy; Killer Ce | 2014 |
Prednisolone treatment reduces endometrial spiral artery development in women with recurrent miscarriage.
Topics: Abortion, Habitual; Actins; Adult; Angiogenesis Inducing Agents; Endometrium; Factor VIII; Female; H | 2011 |
Effect of sairei-to combined with aspirin and prednisolone on four recurrent reproductive failure women who are positive for anti-phospholipid antibodies.
Topics: Abortion, Habitual; Adult; Antibodies, Antiphospholipid; Aspirin; Drug Therapy, Combination; Drugs, | 2003 |
Successful pregnancy outcome following 19 consecutive miscarriages: case report.
Topics: Abortion, Habitual; Cell Count; Female; Humans; Killer Cells, Natural; Prednisolone; Pregnancy; Preg | 2003 |
Prednisolone reduces preconceptual endometrial natural killer cells in women with recurrent miscarriage.
Topics: Abortion, Habitual; Adult; Endometrium; Female; Fertilization; Humans; Killer Cells, Natural; Middle | 2005 |
Intrarater variation--more studies are needed.
Topics: Abortion, Habitual; CD56 Antigen; Female; Humans; Killer Cells, Natural; Observer Variation; Prednis | 2006 |
Prednisolone suppresses NK cell cytotoxicity in vitro in women with a history of infertility and elevated NK cell cytotoxicity.
Topics: Abortion, Habitual; Adult; Coculture Techniques; Cytotoxicity, Immunologic; Female; Humans; Immunogl | 2008 |
Systemic lupus erythematosus and habitual abortion. Case report.
Topics: Abortion, Habitual; Adult; Female; Heart Block; Humans; Infant, Newborn; Lupus Erythematosus, System | 1980 |
Clinical significance of anti-GM3 antibodies in recurrent pregnancy loss with elevated level of antiphospholipid antibodies.
Topics: Abortion, Habitual; Adult; Antibodies, Antiphospholipid; Aspirin; Drug Therapy, Combination; Female; | 1995 |
Pregnancy outcome in women with antiphospholipid antibodies.
Topics: Abortion, Habitual; Adult; Antibodies, Antiphospholipid; Aspirin; Female; Humans; Immune System Dise | 1993 |
[A case of beta 2-glycoprotein I-independent antiphospholipid syndrome].
Topics: Abortion, Habitual; Administration, Oral; Adult; Anti-Inflammatory Agents; Antibodies, Anticardiolip | 1995 |
Severe fetomaternal alloimmune thrombocytopenia presenting with fetal hydrocephalus.
Topics: Abortion, Habitual; Abortion, Spontaneous; Anemia; Antigens, Human Platelet; Female; Fetal Diseases; | 1996 |
Immunosuppressive therapy for recurrent aborters with positive antiphospholipid antibodies and alteration of 6ketoPGF1 alpha/TXB2 ratio.
Topics: 6-Ketoprostaglandin F1 alpha; Abortion, Habitual; Adult; Antibodies, Antiphospholipid; Aspirin; Drug | 1997 |
Postpartum thrombosis after a successful pregnancy in a recurrent aborter strongly positive for antiphospholipid antibodies.
Topics: Abortion, Habitual; Adult; Antibodies, Antiphospholipid; Anticoagulants; Antiphospholipid Syndrome; | 1998 |
Recurrent abortion and moderate or strong antiphospholipid antibody production.
Topics: Abortion, Habitual; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibo | 1998 |
[Pregnancy after four recurrent pregnancy losses: a case report].
Topics: Abortion, Habitual; Adult; Anti-Inflammatory Agents; Antigens, CD; Asthma; Biomarkers; Female; HLA-D | 2000 |
Treatment and outcome of unexplained recurrent spontaneous abortions in subclinical autoimmune disorders.
Topics: Abortion, Habitual; Antibodies, Antinuclear; Aspirin; Autoimmune Diseases; Female; Humans; Infant, N | 1992 |
[Prednisolone and aspirin therapy for habitual abortion associated with anti-cardiolipin antibody].
Topics: Abortion, Habitual; Adult; Antiphospholipid Syndrome; Aspirin; Autoantibodies; Cardiolipins; Drug Th | 1992 |
IgA antiphospholipid and adrenal insufficiency: is there a link?
Topics: Abortion, Habitual; Addison Disease; Adult; Antiphospholipid Syndrome; Aphasia; Female; Hemiplegia; | 1991 |
Recurrent fetal loss with circulating lupus anticoagulant: report of 2 cases.
Topics: Abortion, Habitual; Adult; Aspirin; Blood Coagulation Factors; Drug Therapy, Combination; Female; Hu | 1989 |
Lupus anticoagulant as a risk factor for cerebral infarction and habitual abortions.
Topics: Abortion, Habitual; Adult; Blood Coagulation Factors; Cerebral Infarction; Female; Hemiplegia; Human | 1989 |
[Multiple fetal losses caused by a circulating anticoagulant. Correction with a combination of aspirin and corticotherapy].
Topics: Abortion, Habitual; Adult; Aspirin; Blood Coagulation; Female; Humans; Immunoglobulins; Prednisolone | 1986 |
[Full term pregnancy and Soulier-Boffa syndrome].
Topics: Abortion, Habitual; Adult; Aspirin; Autoimmune Diseases; Drug Therapy, Combination; Female; Humans; | 1988 |
[Prednisolone and aspirin combination therapy in habitual abortion with autoantibodies].
Topics: Abortion, Habitual; Adult; Aspirin; Autoantibodies; Autoimmune Diseases; Drug Therapy, Combination; | 1988 |
[Some clinical-physiological indices in children born of mothers with habitual abortion].
Topics: Abortion, Habitual; Child; Child, Preschool; Congenital Abnormalities; Electroencephalography; Estro | 1971 |