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prednisolone and AIDS-Related Opportunistic Infections

prednisolone has been researched along with AIDS-Related Opportunistic Infections in 21 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

AIDS-Related Opportunistic Infections: Opportunistic infections found in patients who test positive for human immunodeficiency virus (HIV). The most common include PNEUMOCYSTIS PNEUMONIA, Kaposi's sarcoma, cryptosporidiosis, herpes simplex, toxoplasmosis, cryptococcosis, and infections with Mycobacterium avium complex, Microsporidium, and Cytomegalovirus.

Research Excerpts

ExcerptRelevanceReference
" Although the lesion resolved following treatment with intravenous acyclovir and oral steroid, the patient subsequently developed florid disc neovascularization and vitreous hemorrhage."3.71Central retinal vein occlusion due to herpes zoster as the initial presenting sign in a patient with acquired immunodeficiency syndrome (AIDS). ( Biswas, J; Deka, S; Kumarasamy, N; Madhavan, HN; Padmaja, S; Solomon, S, 2001)
"Glucocorticoids are used in pleural tuberculosis to reduce inflammation-induced pathology, and their use also might reduce progression of HIV by suppressing immune activation."2.71A randomized, double-blind, placebo-controlled trial of the use of prednisolone as an adjunct to treatment in HIV-1-associated pleural tuberculosis. ( Ducar, C; Elliott, AM; Ellner, JJ; Johnson, JL; Kyaligonza, S; Luzze, H; Mugerwa, R; Nakiyingi, JS; Namujju, PB; Okwera, A; Quigley, MA; Whitworth, JA, 2004)
"Adjunctive prednisolone for effusive tuberculous pericarditis produced a pronounced reduction in mortality."2.69Double blind randomised placebo controlled trial of adjunctive prednisolone in the treatment of effusive tuberculous pericarditis in HIV seropositive patients. ( Hakim, JG; Malin, A; Mushangi, E; Robertson, V; Siziya, S; Ternouth, I, 2000)
"Immune reconstitution inflammatory syndrome is an inflammatory reaction in HIV-infected patients after initiation of antiretroviral therapy resulting from restored immunity to specific infectious or non-infectious antigens."1.46Nerve abscess in Hansen's disease as part of immune reconstitution inflammatory syndrome: a case report. ( Ali, NM; Kumar, P; Nayak, K, 2017)
"Evan's syndrome, i."1.38Evan's syndrome in HIV infection. ( Lohiy, RV; Sangle, SA, 2012)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (23.81)18.2507
2000's9 (42.86)29.6817
2010's7 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kwon, HY1
Han, YJ1
Im, JH1
Baek, JH1
Lee, JS1
Sangle, SA1
Lohiy, RV1
Bhat, R1
Pinto, M1
Dandakeri, S1
Kambil, S1
Gómez-Traseira, C1
Boyano-Martínez, T1
Escosa-García, L1
Pedrosa, M1
Martín-Muñoz, F1
Quirce, S1
Bogner, JR1
Steinert, D1
Coppenrath, E1
Ali, NM1
Nayak, K1
Kumar, P1
Aoki, T1
Oka, S1
Nakamura, T1
Elliott, AM1
Luzze, H1
Quigley, MA1
Nakiyingi, JS1
Kyaligonza, S1
Namujju, PB1
Ducar, C1
Ellner, JJ2
Whitworth, JA1
Mugerwa, R1
Johnson, JL1
Okwera, A2
Mayanja-Kizza, H1
Jones-Lopez, E1
Wallis, RS1
Mugerwa, RD1
Whalen, CC1
Ulmer, A1
Müller, M1
Bertisch-Möllenhoff, B1
Frietsch, B1
Benfield, TL1
van Steenwijk, R1
Nielsen, TL1
Dichter, JR1
Lipschik, GY1
Jensen, BN1
Junge, J1
Shelhamer, JH1
Lundgren, JD1
Ziegler, D1
Lode, H1
Raffenberg, M1
Schaberg, T1
Mauch, H1
Grassot, A1
Steven, N1
Pithie, A1
Wood, M1
Innes, J1
Ajisawa, A1
Wragg, A1
Strang, JI1
Hakim, JG1
Ternouth, I1
Mushangi, E1
Siziya, S1
Robertson, V1
Malin, A1
Uchida, K1
Inoue, Y1
Kojima, A1
Biswas, J1
Deka, S1
Padmaja, S1
Madhavan, HN1
Kumarasamy, N1
Solomon, S1
Friese, G1
Discher, T1
Füssle, R1
Schmalreck, A1
Lohmeyer, J1
Secchi, AG1
Tognon, MS1
Turrini, B1
Carniel, G1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Efficacy and Safety of Thalidomide in the Adjuvant Treatment of Moderate New Coronavirus (COVID-19) Pneumonia: a Prospective, Multicenter, Randomized, Double-blind, Placebo, Parallel Controlled Clinical Study[NCT04273529]Phase 2100 participants (Anticipated)Interventional2020-02-20Not yet recruiting
The Efficacy and Safety of Thalidomide Combined With Low-dose Hormones in the Treatment of Severe New Coronavirus (COVID-19) Pneumonia: a Prospective, Multicenter, Randomized, Double-blind, Placebo, Parallel Controlled Clinical Study[NCT04273581]Phase 240 participants (Anticipated)Interventional2020-02-18Not yet recruiting
A Randomized Double Blind Placebo Controlled Trial of Adjunctive Dexamethasone for the Treatment of HIV-infected Adults With Tuberculous Meningitis[NCT03092817]Phase 3520 participants (Actual)Interventional2017-05-25Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for prednisolone and AIDS-Related Opportunistic Infections

ArticleYear
[Pneumocystis infections].
    Medical mycology journal, 2012, Volume: 53, Issue:1

    Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Antiretroviral Therapy, Highly Active; Dia

2012
[Pneumocystis carinii pneumonia].
    Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61 Suppl 2

    Topics: AIDS-Related Opportunistic Infections; Bronchoalveolar Lavage Fluid; Humans; Immunocompromised Host;

2003
[Pneumocystis carinii pneumonia].
    Ryoikibetsu shokogun shirizu, 1999, Issue:24 Pt 2

    Topics: AIDS-Related Opportunistic Infections; Anti-Inflammatory Agents; Diagnosis, Differential; Drug Thera

1999

Trials

4 trials available for prednisolone and AIDS-Related Opportunistic Infections

ArticleYear
A randomized, double-blind, placebo-controlled trial of the use of prednisolone as an adjunct to treatment in HIV-1-associated pleural tuberculosis.
    The Journal of infectious diseases, 2004, Sep-01, Volume: 190, Issue:5

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Inflammatory Agents; Antitubercular Agents; Doubl

2004
Immunoadjuvant prednisolone therapy for HIV-associated tuberculosis: a phase 2 clinical trial in Uganda.
    The Journal of infectious diseases, 2005, Mar-15, Volume: 191, Issue:6

    Topics: Adjuvants, Immunologic; Adult; AIDS-Related Opportunistic Infections; Anti-Inflammatory Agents; CD4

2005
Interleukin-8 and eicosanoid production in the lung during moderate to severe Pneumocystis carinii pneumonia in AIDS: a role of interleukin-8 in the pathogenesis of P. carinii pneumonia.
    Respiratory medicine, 1995, Volume: 89, Issue:4

    Topics: Adult; AIDS-Related Opportunistic Infections; Bronchoalveolar Lavage Fluid; Eicosanoids; Female; Hum

1995
Double blind randomised placebo controlled trial of adjunctive prednisolone in the treatment of effusive tuberculous pericarditis in HIV seropositive patients.
    Heart (British Cardiac Society), 2000, Volume: 84, Issue:2

    Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Anti-Inflammatory Agents; Antitubercular A

2000

Other Studies

14 other studies available for prednisolone and AIDS-Related Opportunistic Infections

ArticleYear
Two cases of immune reconstitution inflammatory syndrome in HIV patients treated with thalidomide.
    International journal of STD & AIDS, 2019, Volume: 30, Issue:11

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Brain Edema; Do

2019
Two cases of immune reconstitution inflammatory syndrome in HIV patients treated with thalidomide.
    International journal of STD & AIDS, 2019, Volume: 30, Issue:11

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Brain Edema; Do

2019
Two cases of immune reconstitution inflammatory syndrome in HIV patients treated with thalidomide.
    International journal of STD & AIDS, 2019, Volume: 30, Issue:11

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Brain Edema; Do

2019
Two cases of immune reconstitution inflammatory syndrome in HIV patients treated with thalidomide.
    International journal of STD & AIDS, 2019, Volume: 30, Issue:11

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Brain Edema; Do

2019
Evan's syndrome in HIV infection.
    The Journal of the Association of Physicians of India, 2012, Volume: 60

    Topics: Adult; AIDS-Related Opportunistic Infections; Anemia, Hemolytic, Autoimmune; Antiretroviral Therapy,

2012
Ulcerating type 1 lepra reaction mimicking lazarine leprosy: an unusual presentation of immune reconstitution inflammatory syndrome in an HIV-infected patient.
    International journal of STD & AIDS, 2013, Volume: 24, Issue:12

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Inflammatory Agents; Antiretroviral Therapy, High

2013
Trimethoprim-sulfamethoxazole (cotrimoxazole) desensitization in an HIV-infected 5-yr-old girl.
    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2015, Volume: 26, Issue:3

    Topics: Administration, Oral; AIDS-Related Opportunistic Infections; Antibiotic Prophylaxis; Child, Preschoo

2015
[This far it can go without HIV therapy!].
    MMW Fortschritte der Medizin, 2016, Jun-09, Volume: 158 Suppl 1

    Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Disease Progression; Drug Therapy, Combinati

2016
Nerve abscess in Hansen's disease as part of immune reconstitution inflammatory syndrome: a case report.
    International journal of STD & AIDS, 2017, Volume: 28, Issue:2

    Topics: Abscess; Adult; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Biopsy

2017
Low-dose prednisolone has a CD4-stabilizing effect in pre-treated HIV-patients during structured therapy interruptions (STI).
    European journal of medical research, 2005, Jun-22, Volume: 10, Issue:6

    Topics: AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count;

2005
[Incompatibility of tuberculosis therapy in a patient with AIDS].
    Deutsche medizinische Wochenschrift (1946), 1994, Dec-16, Volume: 119, Issue:50

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Antitubercular Agents; Drug The

1994
Corticosteroid therapy for AIDS patients with Mycobacterium avium-intracellulare infection.
    AIDS (London, England), 1994, Volume: 8, Issue:1

    Topics: Adult; AIDS-Related Opportunistic Infections; Azithromycin; Ciprofloxacin; Clofazimine; Drug Therapy

1994
Tuberculous pericarditis and HIV infection.
    Heart (British Cardiac Society), 2000, Volume: 84, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Anti-Inflammatory Agents; Drug Interactions; Drug Therapy, Co

2000
[Dramatic improvement of severe Pneumocystis carinii pneumonia by corticosteroids despite lack of antipneumocystis therapy in acquired immunodeficiency syndrome].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2000, Volume: 38, Issue:11

    Topics: Adult; AIDS-Related Opportunistic Infections; HIV-1; Humans; Male; Methylprednisolone; Pneumonia, Pn

2000
Central retinal vein occlusion due to herpes zoster as the initial presenting sign in a patient with acquired immunodeficiency syndrome (AIDS).
    Ocular immunology and inflammation, 2001, Volume: 9, Issue:2

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Drug Therapy, Combination

2001
Development of azole resistance during fluconazole maintenance therapy for AIDS-associated cryptococcal disease.
    AIDS (London, England), 2001, Nov-23, Volume: 15, Issue:17

    Topics: Adult; AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Chorioretinitis; Cr

2001
Acute frosted retinal periphlebitis associated with cytomegalovirus retinitis.
    Retina (Philadelphia, Pa.), 1992, Volume: 12, Issue:3

    Topics: Acute Disease; Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Infections; Eye Infecti

1992