prednisolone acetate has been researched along with Ocular Hypertension in 28 studies
prednisolone acetate: RN given refers to cpd with locant for acetate group in position 21 & (11 beta)-isomer
Ocular Hypertension: A condition in which the intraocular pressure is elevated above normal and which may lead to glaucoma.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare adverse intraocular pressure (IOP) spikes in patients receiving intravitreal triamcinolone acetonide (IVTA) in 2 cohorts: (i) patients who underwent a topical prednisolone acetate trial (PAT) without incurring a short-term IOP rise, and (ii) control patients who did not undergo a PAT." | 9.14 | A trial of topical prednisolone acetate before intravitreal triamcinolone acetonide decreases intraocular pressure spikes. ( Gale, J; Hollands, H; Hollands, S; Seif, G, 2010) |
| "To compare intraocular pressure (IOP) outcomes between 2 common, commercially available corticosteroid drops: difluprednate ophthalmic emulsion 0." | 7.85 | Comparison of prednisolone acetate 1.0% and difluprednate ophthalmic emulsion 0.05% after cataract surgery: Incidence of postoperative steroid-induced ocular hypertension. ( Ernest, P; McBain, M; Mian, SI; Musch, DC; Niziol, LM; Person, E; Tijunelis, MA, 2017) |
| "To identify changes in intraocular pressure (IOP) after vitreoretinal surgical procedures in eyes that received either difluprednate ophthalmic emulsion 0." | 7.80 | Incidence of steroid-induced ocular hypertension after vitreoretinal surgery with difluprednate versus prednisolone acetate. ( Connors, DB; Fine, HF; Jeng, KW; Prenner, JL; Roth, D; Wheatley, HM, 2014) |
| "To describe a clinically observed reduction in intraocular pressure (IOP) without increased allograft rejection in known "steroid responders" using loteprednol etabonate 0." | 7.75 | Attenuation of ocular hypertension with the use of topical loteprednol etabonate 0.5% in steroid responders after corneal transplantation. ( Djalilian, AR; Holland, EJ; Sanderson, JP, 2009) |
| "The aim of this study was to investigate the diagnostic value of a topical prednisolone acetate 1% provocative test for steroid-induced ocular hypertension before intravitreal triamcinolone acetonide injection." | 5.34 | The value of prednisolone acetate provocative test before intravitreal triamcinolone acetonide injections. ( Abdullatif, AM; Fouad, HM; Helmy, YAH; Macky, TA; Mansour, K; Saady, AM, 2020) |
| "In dogs that underwent cataract surgery via phacoemulsification, a full week of topical prednisolone acetate treatment prior to surgery did not decrease postoperative inflammation, compared with commencement of topical prednisolone acetate treatment the evening prior to surgery, and was associated with a greater incidence of postoperative ocular hypertension." | 5.16 | Effects of one-week versus one-day preoperative treatment with topical 1% prednisolone acetate in dogs undergoing phacoemulsification. ( Hendrix, DV; McLean, NJ; Vaughn, RK; Ward, DA, 2012) |
| "To compare adverse intraocular pressure (IOP) spikes in patients receiving intravitreal triamcinolone acetonide (IVTA) in 2 cohorts: (i) patients who underwent a topical prednisolone acetate trial (PAT) without incurring a short-term IOP rise, and (ii) control patients who did not undergo a PAT." | 5.14 | A trial of topical prednisolone acetate before intravitreal triamcinolone acetonide decreases intraocular pressure spikes. ( Gale, J; Hollands, H; Hollands, S; Seif, G, 2010) |
| "To determine whether a topical ophthalmic diclofenac sodium formulation containing a proprietary polymeric drug delivery system (ISV-205), when dosed concomitantly with 1% prednisolone acetate, is effective in blocking the intraocular pressure (IOP) response in humans." | 5.10 | Prevention of corticosteroid-induced intraocular pressure elevation using ISV-205. ( Stewart, WC, 2003) |
| "The case concerns an 81-year-old woman on treatment with a topical fixed combination of timolol and brimonidine who was diagnosed in the Emergency Department with acute anterior granulomatous hypertensive uveitis." | 3.88 | Hypertensive acute granulomatous anterior uveitis as a side effect of topical brimonidine. ( Arciniegas-Perasso, CA; Clemente-Tomás, R; Duch-Samper, AM; García-Ibor, F; Hervás-Hernandis, JM; Ruiz-Del Río, N, 2018) |
| "To compare intraocular pressure (IOP) outcomes between 2 common, commercially available corticosteroid drops: difluprednate ophthalmic emulsion 0." | 3.85 | Comparison of prednisolone acetate 1.0% and difluprednate ophthalmic emulsion 0.05% after cataract surgery: Incidence of postoperative steroid-induced ocular hypertension. ( Ernest, P; McBain, M; Mian, SI; Musch, DC; Niziol, LM; Person, E; Tijunelis, MA, 2017) |
| "To identify changes in intraocular pressure (IOP) after vitreoretinal surgical procedures in eyes that received either difluprednate ophthalmic emulsion 0." | 3.80 | Incidence of steroid-induced ocular hypertension after vitreoretinal surgery with difluprednate versus prednisolone acetate. ( Connors, DB; Fine, HF; Jeng, KW; Prenner, JL; Roth, D; Wheatley, HM, 2014) |
| "Intraocular pressure (IOP) was monitored by Perkins applanation tonometry in 16 normal sheep receiving topically administered prednisolone acetate, 0." | 3.76 | Suppression of corticosteroid-induced ocular hypertension in sheep by anecortave. ( Candia, OA; Gerometta, R; Millar, JC; Podos, SM, 2010) |
| "To describe a clinically observed reduction in intraocular pressure (IOP) without increased allograft rejection in known "steroid responders" using loteprednol etabonate 0." | 3.75 | Attenuation of ocular hypertension with the use of topical loteprednol etabonate 0.5% in steroid responders after corneal transplantation. ( Djalilian, AR; Holland, EJ; Sanderson, JP, 2009) |
| "In cases where prednisolone acetate was administered, we found a significant correlation between N363S heterozygosity and steroid-induced ocular hypertension." | 3.74 | The variant N363S of glucocorticoid receptor in steroid-induced ocular hypertension in Hungarian patients treated with photorefractive keratectomy. ( Bányász, I; Borgulya, G; Filkorn, T; Majnik, J; Nagy, ZZ; Szabó, V, 2007) |
| " Initial presentation of the patient was bilateral iridocyclitis, for which he was treated with prednisolone acetate 1% every 2 hours for 6 months." | 3.70 | Systemic toxicity of topical and periocular corticosteroid therapy in an 11-year-old male with posterior uveitis. ( Cheng, L; Freeman, WR; Levi, L; Ozerdem, U; Scher, C; Song, MK, 2000) |
| "Prednisolone drops were discontinued and timolol was started." | 1.35 | Optic neuropathy after epi-LASIK. ( Lessell, S; Montezuma, SR; Pineda, R, 2008) |
| "Steroid-induced ocular hypertension is generally attributed to alterations in the trabecular meshwork, reducing aqueous outflow." | 1.29 | Steroid-induced ocular hypertension in the presence of a functioning Molteno seton. ( Brian, G; Muecke, J, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (10.71) | 18.2507 |
| 2000's | 12 (42.86) | 29.6817 |
| 2010's | 11 (39.29) | 24.3611 |
| 2020's | 2 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Price, MO | 1 |
| Feng, MT | 1 |
| Price, FW | 1 |
| Tijunelis, MA | 1 |
| Person, E | 1 |
| Niziol, LM | 1 |
| Musch, DC | 1 |
| Ernest, P | 1 |
| McBain, M | 1 |
| Mian, SI | 1 |
| Clemente-Tomás, R | 1 |
| Arciniegas-Perasso, CA | 1 |
| Hervás-Hernandis, JM | 1 |
| García-Ibor, F | 1 |
| Ruiz-Del Río, N | 1 |
| Duch-Samper, AM | 1 |
| Saady, AM | 1 |
| Fouad, HM | 1 |
| Abdullatif, AM | 1 |
| Helmy, YAH | 1 |
| Macky, TA | 1 |
| Mansour, K | 1 |
| Jeng, KW | 1 |
| Fine, HF | 1 |
| Wheatley, HM | 1 |
| Roth, D | 1 |
| Connors, DB | 1 |
| Prenner, JL | 1 |
| Jinapriya, D | 1 |
| D'Souza, M | 1 |
| Hollands, H | 2 |
| El-Defrawy, SR | 1 |
| Irrcher, I | 1 |
| Smallman, D | 1 |
| Farmer, JP | 1 |
| Cheung, J | 1 |
| Urton, T | 1 |
| Day, A | 1 |
| Sun, X | 1 |
| Campbell, RJ | 1 |
| Huang, OS | 1 |
| Mehta, JS | 1 |
| Htoon, HM | 1 |
| Tan, DT | 1 |
| Wong, TT | 1 |
| Gerometta, R | 3 |
| Podos, SM | 3 |
| Danias, J | 2 |
| Candia, OA | 3 |
| Erdurmus, M | 1 |
| Cohen, EJ | 1 |
| Yildiz, EH | 1 |
| Hammersmith, KM | 1 |
| Laibson, PR | 1 |
| Varssano, D | 1 |
| Rapuano, CJ | 1 |
| Holland, EJ | 1 |
| Djalilian, AR | 1 |
| Sanderson, JP | 1 |
| Millar, JC | 1 |
| Kaufman, PL | 1 |
| Seif, G | 1 |
| Hollands, S | 1 |
| Gale, J | 1 |
| Chang, DF | 1 |
| Tan, JJ | 1 |
| Tripodis, Y | 1 |
| Ge, Y | 1 |
| Ren, L | 1 |
| Panagis, L | 1 |
| Mittag, TW | 1 |
| McLean, NJ | 1 |
| Ward, DA | 1 |
| Hendrix, DV | 1 |
| Vaughn, RK | 1 |
| Chung, MS | 1 |
| Pepose, JS | 1 |
| El-Agha, MS | 1 |
| Cavanagh, HD | 1 |
| Al-Agha, S | 1 |
| Stewart, WC | 1 |
| Kurian, M | 1 |
| Shetty, R | 1 |
| Shetty, BK | 1 |
| Devi, SA | 1 |
| Frucht-Pery, J | 1 |
| Landau, D | 1 |
| Raiskup, F | 1 |
| Orucov, F | 1 |
| Strassman, E | 1 |
| Blumenthal, EZ | 1 |
| Solomon, A | 1 |
| Szabó, V | 1 |
| Borgulya, G | 1 |
| Filkorn, T | 1 |
| Majnik, J | 1 |
| Bányász, I | 1 |
| Nagy, ZZ | 1 |
| Lam, DS | 1 |
| Leung, DY | 1 |
| Tham, CC | 1 |
| Li, FC | 1 |
| Kwong, YY | 1 |
| Chiu, TY | 1 |
| Fan, DS | 1 |
| Montezuma, SR | 1 |
| Lessell, S | 1 |
| Pineda, R | 1 |
| Muecke, J | 1 |
| Brian, G | 1 |
| Bartlett, JD | 1 |
| Horwitz, B | 1 |
| Laibovitz, R | 1 |
| Howes, JF | 1 |
| Raizman, M | 1 |
| Ozerdem, U | 1 |
| Levi, L | 1 |
| Cheng, L | 1 |
| Song, MK | 1 |
| Scher, C | 1 |
| Freeman, WR | 1 |
| Shaikh, NM | 1 |
| Shaikh, S | 1 |
| Singh, K | 1 |
| Manche, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized, Double-masked, Placebo-controlled Evaluation of Netarsudil for Prevention of Corticosteroid-induced Intraocular Pressure Elevation[NCT03248037] | Phase 3 | 120 participants (Actual) | Interventional | 2017-09-05 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Intraocular pressure measurement exceeding 24 mm Hg or more than 10 mm Hg greater than the pre-randomization reading. (NCT03248037)
Timeframe: from date of randomization until the date of first documented intraocular pressure elevation exceeding defined threshold up to 9 months
| Intervention | Participants (Count of Participants) |
|---|---|
| Netarsudil | 11 |
| Placebo | 18 |
1 review available for prednisolone acetate and Ocular Hypertension
| Article | Year |
|---|---|
Corticosteroid therapy of eye disease. Fifty years later.
Topics: Anti-Inflammatory Agents; Clinical Trials as Topic; Dexamethasone; Eye Diseases; Fluorometholone; Hu | 1996 |
8 trials available for prednisolone acetate and Ocular Hypertension
| Article | Year |
|---|---|
Randomized, Double-Masked Trial of Netarsudil 0.02% Ophthalmic Solution for Prevention of Corticosteroid-Induced Ocular Hypertension.
Topics: Adult; Aged; Aged, 80 and over; Benzoates; beta-Alanine; Double-Blind Method; Female; Follow-Up Stud | 2021 |
The value of prednisolone acetate provocative test before intravitreal triamcinolone acetonide injections.
Topics: Administration, Ophthalmic; Adult; Aged; Anti-Inflammatory Agents; Female; Glucocorticoids; Humans; | 2020 |
Anti-inflammatory therapy after selective laser trabeculoplasty: a randomized, double-masked, placebo-controlled clinical trial.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Anti-Inflammatory Agents; Cross-Sectional Studies; Do | 2014 |
A trial of topical prednisolone acetate before intravitreal triamcinolone acetonide decreases intraocular pressure spikes.
Topics: Administration, Topical; Aged; Choroidal Neovascularization; Follow-Up Studies; Glucocorticoids; Hum | 2010 |
Effects of one-week versus one-day preoperative treatment with topical 1% prednisolone acetate in dogs undergoing phacoemulsification.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Cataract; Dog Diseases; Dogs; Drug Admin | 2012 |
Prevention of corticosteroid-induced intraocular pressure elevation using ISV-205.
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; D | 2003 |
Randomized trial of early phacoemulsification versus peripheral iridotomy to prevent intraocular pressure rise after acute primary angle closure.
Topics: Acute Disease; Aged; Antihypertensive Agents; Cataract; Female; Follow-Up Studies; Glaucoma, Angle-C | 2008 |
Intraocular pressure response to loteprednol etabonate in known steroid responders.
Topics: Adolescent; Adult; Aged; Androstadienes; Anti-Inflammatory Agents; Double-Blind Method; Drug Adminis | 1993 |
19 other studies available for prednisolone acetate and Ocular Hypertension
| Article | Year |
|---|---|
Comparison of prednisolone acetate 1.0% and difluprednate ophthalmic emulsion 0.05% after cataract surgery: Incidence of postoperative steroid-induced ocular hypertension.
Topics: Cataract Extraction; Fluprednisolone; Glucocorticoids; Humans; Incidence; Intraocular Pressure; Ocul | 2017 |
Hypertensive acute granulomatous anterior uveitis as a side effect of topical brimonidine.
Topics: Acute Disease; Adrenergic alpha-2 Receptor Agonists; Aged, 80 and over; Brimonidine Tartrate; Conjun | 2018 |
Incidence of steroid-induced ocular hypertension after vitreoretinal surgery with difluprednate versus prednisolone acetate.
Topics: Emulsions; Female; Fluprednisolone; Glucocorticoids; Humans; Incidence; Intraocular Pressure; Male; | 2014 |
Incidence and Risk Factors of Elevated Intraocular Pressure Following Deep Anterior Lamellar Keratoplasty.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Corneal Transplantation; Cyclosporine; Dexamethasone | 2016 |
Steroid-induced ocular hypertension in normal sheep.
Topics: Administration, Topical; Animals; Disease Models, Animal; Glucocorticoids; Intraocular Pressure; Ocu | 2009 |
Steroid-induced intraocular pressure elevation or glaucoma after penetrating keratoplasty in patients with keratoconus or Fuchs dystrophy.
Topics: Adolescent; Adult; Aged; Androstadienes; Female; Fluorometholone; Fuchs' Endothelial Dystrophy; Glau | 2009 |
Attenuation of ocular hypertension with the use of topical loteprednol etabonate 0.5% in steroid responders after corneal transplantation.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Androstadienes; Anti-Inflammato | 2009 |
Suppression of corticosteroid-induced ocular hypertension in sheep by anecortave.
Topics: Administration, Topical; Angiogenesis Inhibitors; Animals; Aqueous Humor; Disease Models, Animal; Fe | 2010 |
Suppression and reduction of corticosteroid-induced ocular hypertension by anecortave in sheep.
Topics: Angiogenesis Inhibitors; Animals; Disease Models, Animal; Glucocorticoids; Intraocular Pressure; Ocu | 2010 |
Risk factors for steroid response among cataract patients.
Topics: Administration, Topical; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Axial Length, Eye; | 2011 |
Gene expression changes in steroid-induced IOP elevation in bovine trabecular meshwork.
Topics: Animals; Anti-Inflammatory Agents; Cattle; Computational Biology; Disease Models, Animal; Female; Ge | 2011 |
Confocal microscopic findings in a case of delayed-onset bilateral diffuse lamellar keratitis after laser in situ keratomileusis.
Topics: Adult; Cornea; Cyclosporine; Female; Humans; Keratitis; Keratomileusis, Laser In Situ; Microscopy, C | 2002 |
In vivo confocal microscopic findings of interlamellar stromal keratopathy induced by elevated intraocular pressure.
Topics: Acetazolamide; Adult; Antihypertensive Agents; Corneal Diseases; Corneal Stroma; Drug Therapy, Combi | 2006 |
Early transient visual acuity loss after LASIK due to steroid-induced elevation of intraocular pressure.
Topics: Adult; Corneal Topography; Female; Glucocorticoids; Humans; Intraocular Pressure; Keratomileusis, La | 2007 |
The variant N363S of glucocorticoid receptor in steroid-induced ocular hypertension in Hungarian patients treated with photorefractive keratectomy.
Topics: Adult; Corneal Surgery, Laser; Female; Fluorometholone; Genetic Predisposition to Disease; Genetic V | 2007 |
Optic neuropathy after epi-LASIK.
Topics: Adult; Glucocorticoids; Humans; Keratomileusis, Laser In Situ; Male; Myopia; Ocular Hypertension; Op | 2008 |
Steroid-induced ocular hypertension in the presence of a functioning Molteno seton.
Topics: Adolescent; Cataract Extraction; Female; Glaucoma; Humans; Intraocular Pressure; Lenses, Intraocular | 1995 |
Systemic toxicity of topical and periocular corticosteroid therapy in an 11-year-old male with posterior uveitis.
Topics: Acanthosis Nigricans; Administration, Topical; Anti-Inflammatory Agents; Cataract; Child; Cushing Sy | 2000 |
Progression to end-stage glaucoma after laser in situ keratomileusis.
Topics: Adult; Corneal Edema; Disease Progression; Glaucoma; Glucocorticoids; Humans; Intraocular Pressure; | 2002 |