Page last updated: 2024-11-07

prednisolone acetate and Macular Edema

prednisolone acetate has been researched along with Macular Edema in 28 studies

prednisolone acetate: RN given refers to cpd with locant for acetate group in position 21 & (11 beta)-isomer

Macular Edema: Fluid accumulation in the outer layer of the MACULA LUTEA that results from intraocular or systemic insults. It may develop in a diffuse pattern where the macula appears thickened or it may acquire the characteristic petaloid appearance referred to as cystoid macular edema. Although macular edema may be associated with various underlying conditions, it is most commonly seen following intraocular surgery, venous occlusive disease, DIABETIC RETINOPATHY, and posterior segment inflammatory disease. (From Survey of Ophthalmology 2004; 49(5) 470-90)

Research Excerpts

ExcerptRelevanceReference
"To compare adverse intraocular pressure (IOP) spikes in patients receiving intravitreal triamcinolone acetonide (IVTA) in 2 cohorts: (i) patients who underwent a topical prednisolone acetate trial (PAT) without incurring a short-term IOP rise, and (ii) control patients who did not undergo a PAT."9.14A trial of topical prednisolone acetate before intravitreal triamcinolone acetonide decreases intraocular pressure spikes. ( Gale, J; Hollands, H; Hollands, S; Seif, G, 2010)
"To report two cases in which cystoid macular edema developed after initiation of topical latanoprost for glaucoma."7.70Latanoprost-associated cystoid macular edema. ( Callanan, D; Fellman, RL; Savage, JA, 1998)
"Pseudophakic cystoid macular edema (CME) following phacoemulsification is the most common complication after cataract surgery."6.71Pseudophakic cystoid macular edema: ketorolac alone vs. ketorolac plus prednisolone. ( Hopkins, J; Singal, N, 2004)
"The aim of this study was to investigate the diagnostic value of a topical prednisolone acetate 1% provocative test for steroid-induced ocular hypertension before intravitreal triamcinolone acetonide injection."5.34The value of prednisolone acetate provocative test before intravitreal triamcinolone acetonide injections. ( Abdullatif, AM; Fouad, HM; Helmy, YAH; Macky, TA; Mansour, K; Saady, AM, 2020)
"To determine the efficacy of topical ketorolac tromethamine in preventing cystoid macular edema (CME) after uncomplicated cataract surgery."5.19Prophylactic use of ketorolac tromethamine in cataract surgery: a randomized trial. ( Arieta, CE; Lira, RP; Machado, MC; Rodrigues, GB; Ticly, FG; Zanetti, FR, 2014)
"To compare adverse intraocular pressure (IOP) spikes in patients receiving intravitreal triamcinolone acetonide (IVTA) in 2 cohorts: (i) patients who underwent a topical prednisolone acetate trial (PAT) without incurring a short-term IOP rise, and (ii) control patients who did not undergo a PAT."5.14A trial of topical prednisolone acetate before intravitreal triamcinolone acetonide decreases intraocular pressure spikes. ( Gale, J; Hollands, H; Hollands, S; Seif, G, 2010)
"This study was conducted to evaluate the efficacy of two topical steroid prednisolone preparations (Econopred Plus 1%, prednisolone acetate 1%: EPP; Pred Fortedagger 1%, prednisolone acetate 1%: PF) in reducing postoperative inflammation in cataract patients."5.11A clinical comparison of two different prednisolone acetate formulations in patients undergoing cataract surgery. ( Gayton, JL, 2005)
"This article describes the development and characterization of PLGA nanoparticles of dexamethasone (DEX), hydrocortisone acetate (HA), and prednisolone acetate (PA) suspended in thermosensitive gels indicated for the treatment of macular edema (ME)."3.76Novel nanoparticulate gel formulations of steroids for the treatment of macular edema. ( Boddu, SH; Earla, R; Jwala, J; Karla, PK; Mitra, AK; Pal, D; Vaishya, R, 2010)
"To report two cases in which cystoid macular edema developed after initiation of topical latanoprost for glaucoma."3.70Latanoprost-associated cystoid macular edema. ( Callanan, D; Fellman, RL; Savage, JA, 1998)
"Pseudophakic cystoid macular edema (CME) following phacoemulsification is the most common complication after cataract surgery."2.71Pseudophakic cystoid macular edema: ketorolac alone vs. ketorolac plus prednisolone. ( Hopkins, J; Singal, N, 2004)
"Initial angiographic cystoid macular edema was comparable and significantly improved after therapy in the two treatment groups."2.67[Differential treatment of postoperative and uveitis-induced inflammatory cystoid macular edema]. ( Guex-Crosier, Y; Herbort, CP; Othenin-Girard, P, 1992)
"To investigate the incidence and outcomes of cystoid macular edema (CME) after Descemet membrane endothelial keratoplasty (DMEK) alone and DMEK combined with cataract surgery (DMEK triple)."1.62Incidence and Outcomes of Cystoid Macular Edema after Descemet Membrane Endothelial Keratoplasty (DMEK) and DMEK Combined with Cataract Surgery. ( Bae, SS; Ching, G; Covello, AT; Holland, S; Iovieno, A; McCarthy, M; Ritenour, R; Yeung, SN, 2021)
"To analyze the effect of intensified topical steroid therapy after Descemet membrane endothelial keratoplasty combined with cataract surgery (triple-DMEK) on the incidence of postoperative cystoid macular edema (CME)."1.43Intensified Topical Steroids as Prophylaxis for Macular Edema After Posterior Lamellar Keratoplasty Combined With Cataract Surgery. ( Bachmann, BO; Cursiefen, C; Felsch, M; Hoerster, R; Siebelmann, S; Stanzel, TP, 2016)
"Data recorded were visual acuity (VA), recurrences and surgical complications."1.36[Pars plana vitrectomy as anti-inflammatory therapy for intermediate uveitis in children]. ( Arruabarrena, C; Contreras, I; Figueroa, MS; García-Pérez, JL; Gil-Cazorla, R; Noval, S; Sales, M, 2010)
"To report a case of cystoid macular edema (CME) in iridocorneal endothelial syndrome."1.33Macular edema and iridocorneal endothelial syndrome: a case report. ( Acar, MA; Duman, S; Kanpolat, A; Kocaoğlan, H; Unlü, N; Yalvaç, IS, 2005)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (7.14)18.2507
2000's10 (35.71)29.6817
2010's13 (46.43)24.3611
2020's3 (10.71)2.80

Authors

AuthorsStudies
Ilveskoski, L1
Taipale, C1
Tuuminen, R1
Ching, G1
Covello, AT1
Bae, SS1
Holland, S1
McCarthy, M1
Ritenour, R1
Iovieno, A1
Yeung, SN1
Campochiaro, PA1
Han, YS1
Mir, TA1
Kherani, S1
Hafiz, G1
Krispel, C1
Liu, TYA1
Wang, J1
Scott, AW1
Zimmer-Galler, I1
Grewal, DS1
Schwartz, T1
Fekrat, S1
Jasani, KM1
Sharaf, N1
Rog, D1
Aslam, T1
Saady, AM1
Fouad, HM1
Abdullatif, AM1
Helmy, YAH1
Macky, TA1
Mansour, K1
Duong, HV1
Westfield, KC1
Singleton, IC1
Onder, HI1
Alisan, S1
Tunc, M1
Ticly, FG1
Lira, RP1
Zanetti, FR1
Machado, MC1
Rodrigues, GB1
Arieta, CE1
Heinzelmann, S1
Maier, P1
Böhringer, D1
Hüther, S1
Eberwein, P1
Reinhard, T1
Gaskin, JC1
Coote, M1
Shorstein, NH1
Liu, L1
Waxman, MD1
Herrinton, LJ1
Hoerster, R1
Stanzel, TP1
Bachmann, BO1
Siebelmann, S1
Felsch, M1
Cursiefen, C1
Wittpenn, JR1
Silverstein, S1
Heier, J1
Kenyon, KR1
Hunkeler, JD1
Earl, M1
Kim, A1
Stark, WJ1
Sepić-Bilić, T1
Zeneral-Zuza, I1
Alpeza-Dunato, Z1
Njirić, S1
Vojniković, B1
Boddu, SH1
Jwala, J1
Vaishya, R1
Earla, R1
Karla, PK1
Pal, D1
Mitra, AK1
Hollands, H1
Seif, G1
Hollands, S1
Gale, J1
Figueroa, MS1
Noval, S1
Contreras, I1
Arruabarrena, C1
García-Pérez, JL1
Sales, M1
Gil-Cazorla, R1
Mackool, RJ1
Monsanto, VR1
Singal, N1
Hopkins, J1
Kocaoğlan, H1
Unlü, N1
Kanpolat, A1
Yalvaç, IS1
Acar, MA1
Duman, S1
Gayton, JL1
Davis, MJ1
Ravage, ZB1
Packo, KH1
Arevalo, JF1
Bernstein, PS1
Berger, AS1
Callanan, D1
Fellman, RL1
Savage, JA1
Heier, JS1
Topping, TM1
Baumann, W1
Dirks, MS1
Chern, S1
Mohney, BG1
Agarwal, S1
Guex-Crosier, Y1
Othenin-Girard, P1
Herbort, CP1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluating the Efficacy, Compliance, and Patient Satisfaction of a New Dropless Postoperative Regimen After Cataract Surgery in a Vulnerable, County-hospital Population[NCT05157113]Phase 470 participants (Anticipated)Interventional2022-05-31Recruiting
A Masked Comparison of Acular LS Plus Steroid Versus Steroid Alone for the Prevention of Macular Leakage in Cataract Patients[NCT00348244]Phase 40 participants InterventionalCompleted
The Effect of Topical Corticosteroids and Topical NSAIDs Perioperatively on IL6 Levels in Aqueous Humor and on Incidence of PCME in Patients With NPDR[NCT04940338]Phase 490 participants (Actual)Interventional2021-05-01Completed
The Effect of Preoperative Topical Ketorolac 0.45% on Aqueous Cytokine Levels and Macular Thickness in Diabetic and Non Diabetic Patients Undergoing Cataract Surgery[NCT02646072]Phase 480 participants (Actual)Interventional2014-08-31Completed
A Randomized, Masked Comparison of Topical Ketorolac 0,4% Versus Placebo in Cataract Surgery.[NCT01542190]Phase 480 participants (Anticipated)Interventional2011-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

11 trials available for prednisolone acetate and Macular Edema

ArticleYear
Anti-inflammatory Medication of Cataract Surgery in Pseudoexfoliation Syndrome - NSAID Is Needed.
    Current eye research, 2020, Volume: 45, Issue:7

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Benzeneacetamides; Double-Blind Me

2020
Increased Frequency of Topical Steroids Provides Benefit in Patients With Recalcitrant Postsurgical Macular Edema.
    American journal of ophthalmology, 2017, Volume: 178

    Topics: Administration, Topical; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cataract Extraction; Dose-Re

2017
The value of prednisolone acetate provocative test before intravitreal triamcinolone acetonide injections.
    European journal of ophthalmology, 2020, Volume: 30, Issue:4

    Topics: Administration, Ophthalmic; Adult; Aged; Anti-Inflammatory Agents; Female; Glucocorticoids; Humans;

2020
Treatment paradigm after uncomplicated cataract surgery: a prospective evaluation.
    Acta ophthalmologica, 2015, Volume: 93, Issue:4

    Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Azepines; Benzophenones; Bromobenz

2015
Prophylactic use of ketorolac tromethamine in cataract surgery: a randomized trial.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2014, Volume: 30, Issue:6

    Topics: Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cataract Extraction; Double

2014
A randomized, masked comparison of topical ketorolac 0.4% plus steroid vs steroid alone in low-risk cataract surgery patients.
    American journal of ophthalmology, 2008, Volume: 146, Issue:4

    Topics: Administration, Topical; Aged; Anti-Inflammatory Agents, Non-Steroidal; Contrast Sensitivity; Double

2008
A randomized, masked comparison of topical ketorolac 0.4% plus steroid vs steroid alone in low-risk cataract surgery patients.
    American journal of ophthalmology, 2008, Volume: 146, Issue:4

    Topics: Administration, Topical; Aged; Anti-Inflammatory Agents, Non-Steroidal; Contrast Sensitivity; Double

2008
A randomized, masked comparison of topical ketorolac 0.4% plus steroid vs steroid alone in low-risk cataract surgery patients.
    American journal of ophthalmology, 2008, Volume: 146, Issue:4

    Topics: Administration, Topical; Aged; Anti-Inflammatory Agents, Non-Steroidal; Contrast Sensitivity; Double

2008
A randomized, masked comparison of topical ketorolac 0.4% plus steroid vs steroid alone in low-risk cataract surgery patients.
    American journal of ophthalmology, 2008, Volume: 146, Issue:4

    Topics: Administration, Topical; Aged; Anti-Inflammatory Agents, Non-Steroidal; Contrast Sensitivity; Double

2008
A randomized, masked comparison of topical ketorolac 0.4% plus steroid vs steroid alone in low-risk cataract surgery patients.
    American journal of ophthalmology, 2008, Volume: 146, Issue:4

    Topics: Administration, Topical; Aged; Anti-Inflammatory Agents, Non-Steroidal; Contrast Sensitivity; Double

2008
A randomized, masked comparison of topical ketorolac 0.4% plus steroid vs steroid alone in low-risk cataract surgery patients.
    American journal of ophthalmology, 2008, Volume: 146, Issue:4

    Topics: Administration, Topical; Aged; Anti-Inflammatory Agents, Non-Steroidal; Contrast Sensitivity; Double

2008
A randomized, masked comparison of topical ketorolac 0.4% plus steroid vs steroid alone in low-risk cataract surgery patients.
    American journal of ophthalmology, 2008, Volume: 146, Issue:4

    Topics: Administration, Topical; Aged; Anti-Inflammatory Agents, Non-Steroidal; Contrast Sensitivity; Double

2008
A randomized, masked comparison of topical ketorolac 0.4% plus steroid vs steroid alone in low-risk cataract surgery patients.
    American journal of ophthalmology, 2008, Volume: 146, Issue:4

    Topics: Administration, Topical; Aged; Anti-Inflammatory Agents, Non-Steroidal; Contrast Sensitivity; Double

2008
A randomized, masked comparison of topical ketorolac 0.4% plus steroid vs steroid alone in low-risk cataract surgery patients.
    American journal of ophthalmology, 2008, Volume: 146, Issue:4

    Topics: Administration, Topical; Aged; Anti-Inflammatory Agents, Non-Steroidal; Contrast Sensitivity; Double

2008
A randomized, masked comparison of topical ketorolac 0.4% plus steroid vs steroid alone in low-risk cataract surgery patients.
    American journal of ophthalmology, 2008, Volume: 146, Issue:4

    Topics: Administration, Topical; Aged; Anti-Inflammatory Agents, Non-Steroidal; Contrast Sensitivity; Double

2008
A randomized, masked comparison of topical ketorolac 0.4% plus steroid vs steroid alone in low-risk cataract surgery patients.
    American journal of ophthalmology, 2008, Volume: 146, Issue:4

    Topics: Administration, Topical; Aged; Anti-Inflammatory Agents, Non-Steroidal; Contrast Sensitivity; Double

2008
A randomized, masked comparison of topical ketorolac 0.4% plus steroid vs steroid alone in low-risk cataract surgery patients.
    American journal of ophthalmology, 2008, Volume: 146, Issue:4

    Topics: Administration, Topical; Aged; Anti-Inflammatory Agents, Non-Steroidal; Contrast Sensitivity; Double

2008
A randomized, masked comparison of topical ketorolac 0.4% plus steroid vs steroid alone in low-risk cataract surgery patients.
    American journal of ophthalmology, 2008, Volume: 146, Issue:4

    Topics: Administration, Topical; Aged; Anti-Inflammatory Agents, Non-Steroidal; Contrast Sensitivity; Double

2008
A randomized, masked comparison of topical ketorolac 0.4% plus steroid vs steroid alone in low-risk cataract surgery patients.
    American journal of ophthalmology, 2008, Volume: 146, Issue:4

    Topics: Administration, Topical; Aged; Anti-Inflammatory Agents, Non-Steroidal; Contrast Sensitivity; Double

2008
A randomized, masked comparison of topical ketorolac 0.4% plus steroid vs steroid alone in low-risk cataract surgery patients.
    American journal of ophthalmology, 2008, Volume: 146, Issue:4

    Topics: Administration, Topical; Aged; Anti-Inflammatory Agents, Non-Steroidal; Contrast Sensitivity; Double

2008
A randomized, masked comparison of topical ketorolac 0.4% plus steroid vs steroid alone in low-risk cataract surgery patients.
    American journal of ophthalmology, 2008, Volume: 146, Issue:4

    Topics: Administration, Topical; Aged; Anti-Inflammatory Agents, Non-Steroidal; Contrast Sensitivity; Double

2008
A trial of topical prednisolone acetate before intravitreal triamcinolone acetonide decreases intraocular pressure spikes.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2010, Volume: 45, Issue:5

    Topics: Administration, Topical; Aged; Choroidal Neovascularization; Follow-Up Studies; Glucocorticoids; Hum

2010
Pseudophakic cystoid macular edema: ketorolac alone vs. ketorolac plus prednisolone.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2004, Volume: 39, Issue:3

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cataract Extraction; Double-Blind

2004
A clinical comparison of two different prednisolone acetate formulations in patients undergoing cataract surgery.
    Current medical research and opinion, 2005, Volume: 21, Issue:8

    Topics: Aged; Cataract Extraction; Female; Glucocorticoids; Humans; Inflammation; Lens Implantation, Intraoc

2005
Ketorolac versus prednisolone versus combination therapy in the treatment of acute pseudophakic cystoid macular edema.
    Ophthalmology, 2000, Volume: 107, Issue:11

    Topics: Acute Disease; Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cataract Ext

2000
[Differential treatment of postoperative and uveitis-induced inflammatory cystoid macular edema].
    Klinische Monatsblatter fur Augenheilkunde, 1992, Volume: 200, Issue:5

    Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Diclofenac; Female; Humans; Injections; Lenses, Intra

1992

Other Studies

17 other studies available for prednisolone acetate and Macular Edema

ArticleYear
Incidence and Outcomes of Cystoid Macular Edema after Descemet Membrane Endothelial Keratoplasty (DMEK) and DMEK Combined with Cataract Surgery.
    Current eye research, 2021, Volume: 46, Issue:5

    Topics: Administration, Ophthalmic; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Anti-Inflammatory Age

2021
Sequential Sterile Intraocular Inflammation Associated With Consecutive Intravitreal Injections of Aflibercept and Ranibizumab.
    Ophthalmic surgery, lasers & imaging retina, 2017, 05-01, Volume: 48, Issue:5

    Topics: Administration, Topical; Aged, 80 and over; Angiogenesis Inhibitors; Anti-Inflammatory Agents; Femal

2017
Fingolimod-associated macular oedema.
    BMJ case reports, 2017, Jun-15, Volume: 2017

    Topics: Anti-Inflammatory Agents; Female; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Macula

2017
Serous retinal detachment and cystoid macular edema in a patient with Wyburn-Mason syndrome.
    Seminars in ophthalmology, 2015, Volume: 30, Issue:2

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Arteriovenous Fistula;

2015
Cystoid macular oedema following Descemet membrane endothelial keratoplasty.
    The British journal of ophthalmology, 2015, Volume: 99, Issue:1

    Topics: Aged; Aged, 80 and over; Cataract Extraction; Corneal Diseases; Cyclooxygenase Inhibitors; Descemet

2015
Postoperative cystoid macular oedema in a patient on fingolimod.
    BMJ case reports, 2015, May-12, Volume: 2015

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cataract Extraction; Diclofenac; Female; Fingolimod Hydroch

2015
Comparative Effectiveness of Three Prophylactic Strategies to Prevent Clinical Macular Edema after Phacoemulsification Surgery.
    Ophthalmology, 2015, Volume: 122, Issue:12

    Topics: Administration, Topical; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Diclofena

2015
Intensified Topical Steroids as Prophylaxis for Macular Edema After Posterior Lamellar Keratoplasty Combined With Cataract Surgery.
    American journal of ophthalmology, 2016, Volume: 163

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Cataract; Corneal Diseases; Descemet Stripp

2016
Are topical NSAIDs needed for routine cataract surgery?
    American journal of ophthalmology, 2008, Volume: 146, Issue:4

    Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Glucocor

2008
Dental inflammation and central retinitis--it is important to protect the retina from the harmful sunlight.
    Collegium antropologicum, 2008, Volume: 32 Suppl 2

    Topics: Anti-Bacterial Agents; Eye Protective Devices; Humans; Inflammation; Macular Edema; Photophobia; Pre

2008
Novel nanoparticulate gel formulations of steroids for the treatment of macular edema.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2010, Volume: 26, Issue:1

    Topics: Animals; Delayed-Action Preparations; Dexamethasone; Dialysis; Emulsions; Gels; Glucocorticoids; Hyd

2010
[Pars plana vitrectomy as anti-inflammatory therapy for intermediate uveitis in children].
    Archivos de la Sociedad Espanola de Oftalmologia, 2010, Volume: 85, Issue:12

    Topics: Adolescent; Anti-Inflammatory Agents; Cataract; Child; Child, Preschool; Combined Modality Therapy;

2010
Role of the bandage contact lens in the management of concomitant keratoconjunctivitis medicamentosa and cystoid macular edema.
    Journal of cataract and refractive surgery, 2002, Volume: 28, Issue:9

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Bandages; Contact Lenses; Female; Humans; Keratoconju

2002
Macular edema and iridocorneal endothelial syndrome: a case report.
    Cornea, 2005, Volume: 24, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Corneal Diseases; Drug Therapy, Combination; Endothe

2005
Diagnostic and therapeutic challenges.
    Retina (Philadelphia, Pa.), 2008, Volume: 28, Issue:3

    Topics: Aged; Cataract Extraction; Fluorescein Angiography; Glucocorticoids; Humans; Hypolipidemic Agents; L

2008
Latanoprost-associated cystoid macular edema.
    American journal of ophthalmology, 1998, Volume: 126, Issue:1

    Topics: Administration, Topical; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Female; G

1998
Cystoid macular edema following extraocular muscle surgery.
    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2002, Volume: 6, Issue:2

    Topics: Aged; Diplopia; Drug Therapy, Combination; Female; Fluorescein Angiography; Glucocorticoids; Humans;

2002