prednisolone acetate has been researched along with Inflammation in 25 studies
prednisolone acetate: RN given refers to cpd with locant for acetate group in position 21 & (11 beta)-isomer
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Difluprednate administered twice a day was at least as effective as prednisolone acetate administered 4 times a day for inflammatory treatment after cataract surgery." | 9.51 | Difluprednate 0.05% twice a day vs prednisolone acetate 1% 4 times a day for cataract postsurgical inflammation treatment: noninferiority trial. ( Del Papa, M; Ferroni, C; Ferroni, V; Idiart, C; Kaufer, R; Marino, F; Masseroni, M; Nuñez, M; Passerini, MS; Valvecchia, G; Zaldívar, R, 2022) |
| "5% with prednisolone acetate suspension (PA) 1% for the treatment of inflammation after cataract surgery in children." | 9.34 | Loteprednol etabonate gel 0.5% vs prednisolone acetate suspension 1% for the treatment of inflammation after cataract surgery in children. ( Vittitow, JL; Williams, JI, 2020) |
| "The results indicate that equivalent control of inflammation can be obtained through treatment with loteprednol etabonate or prednisolone acetate after cataract surgery." | 9.17 | Loteprednol etabonate 0.5% versus prednisolone acetate 1.0% for the treatment of inflammation after cataract surgery. ( Holland, EJ; Lane, SS, 2013) |
| "To compare the efficacy of two formulations of prednisolone acetate 1% in reducing postoperative inflammation in patients having primary phacoemulsification surgery with IOL implantation." | 9.12 | Clinical comparison of two topical prednisolone acetate 1% formulations in reducing inflammation after cataract surgery. ( Donnenfeld, ED; Raizman, MB; Weinstein, AJ, 2007) |
| "Rimexolone 1% ophthalmic suspension is both an effective and safe topical steroid in controlling postoperative inflammation after cataract extraction with phacoemulsification." | 9.11 | Efficacy and safety of rimexolone 1% versus prednisolone acetate 1% in the control of postoperative inflammation following phacoemulsification cataract surgery. ( Ozbay, D; Ozden, S; Tatlipinar, S; Yaylali, V; Yildirim, C, 2004) |
| "Separate, randomized, double-masked clinical studies were conducted to determine the therapeutic efficacy of fluorometholone acetate, a new ophthalmic corticosteroid formulation, in suppressing external ocular inflammation (conjunctivitis, episcleritis, scleritis)." | 9.05 | Fluorometholone acetate: clinical evaluation in the treatment of external ocular inflammation. ( Hyndiuk, RA; Leibowitz, HM; Lindsey, C; Rosenthal, AL, 1984) |
| "To assess the efficacy of a biodegradable, prednisolone acetate implant in a rabbit uveitis model." | 7.80 | Evaluation of a prednisolone acetate-loaded subconjunctival implant for the treatment of recurrent uveitis in a rabbit model. ( Ang, M; Chee, SP; Ng, X; Venkatraman, SS; Wong, C; Wong, TT; Yan, P, 2014) |
| "All subjects (healthy volunteers or patients with inflammation or allergy) in all sponsored loteprednol etabonate studies in the United States were evaluated." | 7.70 | Change in intraocular pressure during long-term use of loteprednol etabonate. ( Crockett, RS; Howes, J; Novack, GD; Sherwood, MB, 1998) |
| " Safety included evaluation of adverse events." | 6.82 | Difluprednate versus prednisolone acetate for inflammation following cataract surgery in pediatric patients: a randomized safety and efficacy study. ( Gedif, K; Lambert, SR; Markwardt, K; O'Halloran, H; Plager, DA; Roarty, J; VanderVeen, D; Wilson, ME, 2016) |
| "Difluprednate administered twice a day was at least as effective as prednisolone acetate administered 4 times a day for inflammatory treatment after cataract surgery." | 5.51 | Difluprednate 0.05% twice a day vs prednisolone acetate 1% 4 times a day for cataract postsurgical inflammation treatment: noninferiority trial. ( Del Papa, M; Ferroni, C; Ferroni, V; Idiart, C; Kaufer, R; Marino, F; Masseroni, M; Nuñez, M; Passerini, MS; Valvecchia, G; Zaldívar, R, 2022) |
| "5% with prednisolone acetate suspension (PA) 1% for the treatment of inflammation after cataract surgery in children." | 5.34 | Loteprednol etabonate gel 0.5% vs prednisolone acetate suspension 1% for the treatment of inflammation after cataract surgery in children. ( Vittitow, JL; Williams, JI, 2020) |
| "The results indicate that equivalent control of inflammation can be obtained through treatment with loteprednol etabonate or prednisolone acetate after cataract surgery." | 5.17 | Loteprednol etabonate 0.5% versus prednisolone acetate 1.0% for the treatment of inflammation after cataract surgery. ( Holland, EJ; Lane, SS, 2013) |
| "In this high-dose pulsed-therapy regimen, difluprednate reduced inflammation more effectively than prednisolone acetate, resulting in more rapid return of vision." | 5.15 | A multicenter randomized controlled fellow eye trial of pulse-dosed difluprednate 0.05% versus prednisolone acetate 1% in cataract surgery. ( Donnenfeld, ED; Fiore, J; Gobbo, A; Holland, EJ; Perry, HD; Prince, J; Sandoval, HP; Shull, ER; Solomon, KD, 2011) |
| "A single posterior subtenon injection of TA can be as effective and safe as a 4-week regimen of prednisolone acetate 1% eyedrops in controlling intraocular inflammation after PPV." | 5.12 | Anti-inflammatory efficacy of a single posterior subtenon injection of triamcinolone acetonide versus prednisolone acetate 1% eyedrops after pars plana vitrectomy. ( Barbosa, JC; Costa, RA; Jorge, R; Paccola, L; Scott, IU, 2007) |
| "To compare the efficacy of two formulations of prednisolone acetate 1% in reducing postoperative inflammation in patients having primary phacoemulsification surgery with IOL implantation." | 5.12 | Clinical comparison of two topical prednisolone acetate 1% formulations in reducing inflammation after cataract surgery. ( Donnenfeld, ED; Raizman, MB; Weinstein, AJ, 2007) |
| "Rimexolone 1% ophthalmic suspension is both an effective and safe topical steroid in controlling postoperative inflammation after cataract extraction with phacoemulsification." | 5.11 | Efficacy and safety of rimexolone 1% versus prednisolone acetate 1% in the control of postoperative inflammation following phacoemulsification cataract surgery. ( Ozbay, D; Ozden, S; Tatlipinar, S; Yaylali, V; Yildirim, C, 2004) |
| "This study was conducted to evaluate the efficacy of two topical steroid prednisolone preparations (Econopred Plus 1%, prednisolone acetate 1%: EPP; Pred Fortedagger 1%, prednisolone acetate 1%: PF) in reducing postoperative inflammation in cataract patients." | 5.11 | A clinical comparison of two different prednisolone acetate formulations in patients undergoing cataract surgery. ( Gayton, JL, 2005) |
| "To compare the effects of a topical nonsteroidal anti-inflammatory agent, diclofenac, and prednisolone acetate on wound healing, postoperative inflammation, and other clinical parameters in laser in situ keratomileusis (LASIK) patients." | 5.09 | Effects of topical diclofenac and prednisolone eyedrops in laser in situ keratomileusis patients. ( Juárez, CP; Luna, JD; Muiño, JC; Vantesone, DL, 1999) |
| "Separate, randomized, double-masked clinical studies were conducted to determine the therapeutic efficacy of fluorometholone acetate, a new ophthalmic corticosteroid formulation, in suppressing external ocular inflammation (conjunctivitis, episcleritis, scleritis)." | 5.05 | Fluorometholone acetate: clinical evaluation in the treatment of external ocular inflammation. ( Hyndiuk, RA; Leibowitz, HM; Lindsey, C; Rosenthal, AL, 1984) |
| "Eyes receiving celecoxib-IOL/PA had better initial control of inflammation." | 3.81 | Efficacy of COX-2 inhibitors in controlling inflammation and capsular opacification after phacoemulsification cataract removal. ( Brookshire, HL; English, RV; Gift, BW; Gilger, BC; Nadelstein, B; Weigt, AK, 2015) |
| "To assess the efficacy of a biodegradable, prednisolone acetate implant in a rabbit uveitis model." | 3.80 | Evaluation of a prednisolone acetate-loaded subconjunctival implant for the treatment of recurrent uveitis in a rabbit model. ( Ang, M; Chee, SP; Ng, X; Venkatraman, SS; Wong, C; Wong, TT; Yan, P, 2014) |
| "All subjects (healthy volunteers or patients with inflammation or allergy) in all sponsored loteprednol etabonate studies in the United States were evaluated." | 3.70 | Change in intraocular pressure during long-term use of loteprednol etabonate. ( Crockett, RS; Howes, J; Novack, GD; Sherwood, MB, 1998) |
| " Safety included evaluation of adverse events." | 2.82 | Difluprednate versus prednisolone acetate for inflammation following cataract surgery in pediatric patients: a randomized safety and efficacy study. ( Gedif, K; Lambert, SR; Markwardt, K; O'Halloran, H; Plager, DA; Roarty, J; VanderVeen, D; Wilson, ME, 2016) |
| "Thus diclofenac sodium was as effective an anti-inflammatory agent for postoperative inflammation as prednisolone acetate." | 2.67 | A comparison of topical non-steroidal anti-inflammatory drugs to steroids for control of post cataract inflammation. ( Brennan, KM; Brown, RM; Roberts, CW, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (8.00) | 18.7374 |
| 1990's | 3 (12.00) | 18.2507 |
| 2000's | 6 (24.00) | 29.6817 |
| 2010's | 11 (44.00) | 24.3611 |
| 2020's | 3 (12.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Valvecchia, G | 1 |
| Kaufer, R | 1 |
| Ferroni, C | 1 |
| Zaldívar, R | 1 |
| Masseroni, M | 1 |
| Idiart, C | 1 |
| Ferroni, V | 1 |
| Marino, F | 1 |
| Nuñez, M | 1 |
| Del Papa, M | 1 |
| Passerini, MS | 1 |
| Hovanesian, JA | 1 |
| Donnenfeld, ED | 3 |
| Vittitow, JL | 1 |
| Williams, JI | 1 |
| Yan, H | 1 |
| Wang, Y | 1 |
| Shen, S | 1 |
| Wu, Z | 1 |
| Wan, P | 1 |
| Hanafy, AF | 1 |
| Abdalla, AM | 1 |
| Guda, TK | 1 |
| Gabr, KE | 1 |
| Royall, PG | 1 |
| Alqurshi, A | 1 |
| Beyazyıldız, E | 1 |
| Acar, U | 1 |
| Beyazyıldız, Ö | 1 |
| Pınarlı, FA | 1 |
| Albayrak, A | 1 |
| Uğurlu, N | 1 |
| Tiryaki, M | 1 |
| Delibaşi, T | 1 |
| Brookshire, HL | 1 |
| English, RV | 1 |
| Nadelstein, B | 1 |
| Weigt, AK | 1 |
| Gift, BW | 1 |
| Gilger, BC | 1 |
| Ang, M | 1 |
| Ng, X | 1 |
| Wong, C | 1 |
| Yan, P | 1 |
| Chee, SP | 1 |
| Venkatraman, SS | 1 |
| Wong, TT | 1 |
| Wilson, ME | 2 |
| O'Halloran, H | 2 |
| VanderVeen, D | 2 |
| Roarty, J | 2 |
| Plager, DA | 2 |
| Markwardt, K | 1 |
| Gedif, K | 1 |
| Lambert, SR | 2 |
| Kaur, S | 1 |
| Sukhija, J | 1 |
| Sepić-Bilić, T | 1 |
| Zeneral-Zuza, I | 1 |
| Alpeza-Dunato, Z | 1 |
| Njirić, S | 1 |
| Vojniković, B | 1 |
| Holland, EJ | 2 |
| Solomon, KD | 1 |
| Fiore, J | 1 |
| Gobbo, A | 1 |
| Prince, J | 1 |
| Sandoval, HP | 1 |
| Shull, ER | 1 |
| Perry, HD | 1 |
| Lane, SS | 1 |
| VOGEL, G | 1 |
| Yaylali, V | 1 |
| Ozbay, D | 1 |
| Tatlipinar, S | 1 |
| Yildirim, C | 1 |
| Ozden, S | 1 |
| Gayton, JL | 1 |
| Bolinder, A | 1 |
| Cameron, K | 1 |
| Faubert, L | 1 |
| Wilson, J | 1 |
| Aramini, J | 1 |
| Hare, J | 1 |
| Paccola, L | 1 |
| Jorge, R | 1 |
| Barbosa, JC | 1 |
| Costa, RA | 1 |
| Scott, IU | 1 |
| Raizman, MB | 1 |
| Weinstein, AJ | 1 |
| Leibowitz, HM | 1 |
| Hyndiuk, RA | 1 |
| Lindsey, C | 1 |
| Rosenthal, AL | 1 |
| Brennan, KM | 1 |
| Brown, RM | 1 |
| Roberts, CW | 1 |
| Novack, GD | 1 |
| Howes, J | 1 |
| Crockett, RS | 1 |
| Sherwood, MB | 1 |
| Vantesone, DL | 1 |
| Luna, JD | 1 |
| Muiño, JC | 1 |
| Juárez, CP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The D3 Study: Drug Delivery vs Drops - A Prospective Clinical Study Evaluating Dexycu vs Prednisolone Acetate 1% in Controlling Post-operative Pain and Inflammation in Patients Undergoing Sequential Cataract Surgery[NCT04273282] | Phase 4 | 31 participants (Actual) | Interventional | 2019-12-16 | Completed | ||
| A Randomized, Masked Multi-center Safety & Efficacy Study of the Effects of Preoperative & Postoperative Cataract Surgery Use of Difluprednate Ophthalmic Emulsion, 0.05% Compared to Prednisolone Acetate Ophthalmic Suspension 1% on Visual Acuity & Corneal [NCT01244334] | Phase 4 | 52 participants (Actual) | Interventional | 2009-03-31 | Completed | ||
| Dropless Pars Plana Vitrectomy Study[NCT05331664] | Phase 4 | 168 participants (Anticipated) | Interventional | 2022-07-25 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
13 trials available for prednisolone acetate and Inflammation
| Article | Year |
|---|---|
Difluprednate 0.05% twice a day vs prednisolone acetate 1% 4 times a day for cataract postsurgical inflammation treatment: noninferiority trial.
Topics: Cataract; Eye Diseases; Fluprednisolone; Humans; Inflammation; Phacoemulsification; Postoperative Co | 2022 |
Intracameral dexamethasone 9% vs prednisolone acetate 1% in controlling postoperative pain and inflammation in patients undergoing cataract surgery.
Topics: Cataract; Cataract Extraction; Dexamethasone; Humans; Inflammation; Moxifloxacin; Ophthalmic Solutio | 2022 |
Loteprednol etabonate gel 0.5% vs prednisolone acetate suspension 1% for the treatment of inflammation after cataract surgery in children.
Topics: Androstadienes; Cataract; Child; Double-Blind Method; Humans; Inflammation; Intraocular Pressure; Lo | 2020 |
Difluprednate versus prednisolone acetate for inflammation following cataract surgery in pediatric patients: a randomized safety and efficacy study.
Topics: Administration, Topical; Aphakia, Postcataract; Cataract; Cataract Extraction; Child, Preschool; Dou | 2016 |
A multicenter randomized controlled fellow eye trial of pulse-dosed difluprednate 0.05% versus prednisolone acetate 1% in cataract surgery.
Topics: Aged; Aged, 80 and over; Cell Count; Cornea; Corneal Edema; Double-Blind Method; Endothelium, Cornea | 2011 |
Loteprednol etabonate 0.5% versus prednisolone acetate 1.0% for the treatment of inflammation after cataract surgery.
Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Anterior Chamber; Anti-Allergic Agents; Anti-Inflamm | 2013 |
Efficacy and safety of rimexolone 1% versus prednisolone acetate 1% in the control of postoperative inflammation following phacoemulsification cataract surgery.
Topics: Double-Blind Method; Female; Glucocorticoids; Humans; Inflammation; Lens Implantation, Intraocular; | 2004 |
A clinical comparison of two different prednisolone acetate formulations in patients undergoing cataract surgery.
Topics: Aged; Cataract Extraction; Female; Glucocorticoids; Humans; Inflammation; Lens Implantation, Intraoc | 2005 |
Anti-inflammatory efficacy of a single posterior subtenon injection of triamcinolone acetonide versus prednisolone acetate 1% eyedrops after pars plana vitrectomy.
Topics: Aged; Anti-Inflammatory Agents; Connective Tissue; Double-Blind Method; Endophthalmitis; Female; Hum | 2007 |
Clinical comparison of two topical prednisolone acetate 1% formulations in reducing inflammation after cataract surgery.
Topics: Administration, Topical; Anti-Inflammatory Agents; Cataract Extraction; Chemistry, Pharmaceutical; D | 2007 |
Fluorometholone acetate: clinical evaluation in the treatment of external ocular inflammation.
Topics: Adult; Clinical Trials as Topic; Conjunctivitis; Double-Blind Method; Eye Diseases; Female; Fluorome | 1984 |
A comparison of topical non-steroidal anti-inflammatory drugs to steroids for control of post cataract inflammation.
Topics: Cataract Extraction; Diclofenac; Eye Diseases; Humans; Inflammation; Lenses, Intraocular; Postoperat | 1993 |
Effects of topical diclofenac and prednisolone eyedrops in laser in situ keratomileusis patients.
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; C | 1999 |
12 other studies available for prednisolone acetate and Inflammation
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
Corticosteroids effects on LPS-induced rat inflammatory keratocyte cell model.
Topics: Adrenal Cortex Hormones; Animals; Blotting, Western; Cells, Cultured; Collagen Type VI; Corneal Kera | 2017 |
Ocular anti-inflammatory activity of prednisolone acetate loaded chitosan-deoxycholate self-assembled nanoparticles.
Topics: Animals; Anti-Inflammatory Agents; Calorimetry, Differential Scanning; Chitosan; Deoxycholic Acid; D | 2019 |
Comparison of prednisolone acetate and loteprednol etabonate for the treatment of benzalkonium chloride-induced dry eye syndrome in rats.
Topics: Administration, Topical; Androstadienes; Animals; Benzalkonium Compounds; Disease Models, Animal; Dr | 2014 |
Efficacy of COX-2 inhibitors in controlling inflammation and capsular opacification after phacoemulsification cataract removal.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzophenones; Bromobenzenes; Celecoxib; Cyclooxyg | 2015 |
Evaluation of a prednisolone acetate-loaded subconjunctival implant for the treatment of recurrent uveitis in a rabbit model.
Topics: Animals; Conjunctiva; Drug Administration Routes; Inflammation; Male; Prednisolone; Prostheses and I | 2014 |
Difluprednate versus prednisolone acetate for inflammation following cataract surgery in pediatric patients: a randomized safety and efficacy study.
Topics: Anti-Inflammatory Agents; Cataract; Cataract Extraction; Child; Double-Blind Method; Fluprednisolone | 2017 |
Difluprednate versus prednisolone acetate for inflammation following cataract surgery in pediatric patients: a randomized safety and efficacy study.
Topics: Anti-Inflammatory Agents; Cataract; Cataract Extraction; Child; Double-Blind Method; Fluprednisolone | 2017 |
Dental inflammation and central retinitis--it is important to protect the retina from the harmful sunlight.
Topics: Anti-Bacterial Agents; Eye Protective Devices; Humans; Inflammation; Macular Edema; Photophobia; Pre | 2008 |
[Intensity and duration of the anti-inflammatory and glycogenetic effect of prednisolone and prednisolone acetate after oral and subcutaneous administration to rats].
Topics: Animals; Anti-Inflammatory Agents; Edema; Inflammation; Liver Glycogen; Prednisolone; Rats | 1963 |
In vivo efficacy study of the anti-inflammatory properties of Surolan.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Ear; Female; Inflam | 2006 |
Change in intraocular pressure during long-term use of loteprednol etabonate.
Topics: Androstadienes; Anti-Inflammatory Agents; Clinical Trials as Topic; Humans; Hypersensitivity; Inflam | 1998 |