prednisolone acetate has been researched along with Disease Models, Animal in 29 studies
prednisolone acetate: RN given refers to cpd with locant for acetate group in position 21 & (11 beta)-isomer
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "05% cyclosporine A is as effective as 2% cyclosporine A and epinastine in suppressing mast cell-mediated type I allergic conjunctivitis in an experimental allergic conjunctivitis model." | 7.79 | Comparison of the effects of topical cyclosporine a 0.05%, cyclosporine a 2%, epinastine hydrochloride 0.05%, and prednisolone acetate 1% on allergic inflammation in an experimental allergic conjunctivitis model. ( Nigar, V; Semsettin, B; Sinan, E, 2013) |
| "To evaluate the effect of a biodegradable microfilm with sustained release of prednisolone acetate (PA) on postoperative wound healing after experimental glaucoma filtration surgery (GFS)." | 7.77 | Evaluation of sustained release of PLC-loaded prednisolone acetate microfilm on postoperative inflammation in an experimental model of glaucoma filtration surgery. ( Ang, M; Foo, S; Venkatraman, SS; Wong, TT; Yan, P; Zhen, M, 2011) |
| "In order to induce experimental steroid cataracts in rat eyes similar morphologically to those seen in human eyes, prednisolone acetate was administered either topically or systemically for 12 months with a low dose of X-irradiation as a cocataractogenic factor." | 7.69 | A new steroid-induced cataract model in the rat: long-term prednisolone applications with a minimum of X-irradiation. ( Kojima, M; Sasaki, K; Shui, YB, 1996) |
| "05% cyclosporine A is as effective as 2% cyclosporine A and epinastine in suppressing mast cell-mediated type I allergic conjunctivitis in an experimental allergic conjunctivitis model." | 3.79 | Comparison of the effects of topical cyclosporine a 0.05%, cyclosporine a 2%, epinastine hydrochloride 0.05%, and prednisolone acetate 1% on allergic inflammation in an experimental allergic conjunctivitis model. ( Nigar, V; Semsettin, B; Sinan, E, 2013) |
| " Animals were treated for 10 days after the onset of keratitis with albumin, VIG, prednisolone acetate, trifluridine, or combinations thereof." | 3.77 | Evaluation of therapeutic interventions for vaccinia virus keratitis. ( Adkins, E; Altmann, S; Brandt, CR; Covert, J; Dubielzig, R; Kodihalli, S; Leatherberry, G; McIntyre, K; Murphy, CJ; Nesbit, B; Patnaikuni, R; Takla, T; Toomey, M, 2011) |
| "Inflammatory corneal neovascularization was induced by suture placement, and the corneas were then treated with topical fluorometholone, prednisolone acetate, or dexamethasone sodium phosphate." | 3.77 | Suppression of inflammatory corneal lymphangiogenesis by application of topical corticosteroids. ( Bock, F; Cursiefen, C; Hos, D; Masli, S; Onderka, J; Regenfuss, B; Saban, DR, 2011) |
| "To evaluate the effect of a biodegradable microfilm with sustained release of prednisolone acetate (PA) on postoperative wound healing after experimental glaucoma filtration surgery (GFS)." | 3.77 | Evaluation of sustained release of PLC-loaded prednisolone acetate microfilm on postoperative inflammation in an experimental model of glaucoma filtration surgery. ( Ang, M; Foo, S; Venkatraman, SS; Wong, TT; Yan, P; Zhen, M, 2011) |
| "Intraocular pressure (IOP) was monitored by Perkins applanation tonometry in 16 normal sheep receiving topically administered prednisolone acetate, 0." | 3.76 | Suppression of corticosteroid-induced ocular hypertension in sheep by anecortave. ( Candia, OA; Gerometta, R; Millar, JC; Podos, SM, 2010) |
| "In order to induce experimental steroid cataracts in rat eyes similar morphologically to those seen in human eyes, prednisolone acetate was administered either topically or systemically for 12 months with a low dose of X-irradiation as a cocataractogenic factor." | 3.69 | A new steroid-induced cataract model in the rat: long-term prednisolone applications with a minimum of X-irradiation. ( Kojima, M; Sasaki, K; Shui, YB, 1996) |
| "1% fluorometholone acetate ophthalmic suspension produced, on the average, a 47% reduction in the polymorphonuclear leukocytes invading the cornea during an experimentally induced inflammatory keratitis." | 3.66 | Fluorometholone acetate. A new ophthalmic derivative of fluorometholone. ( Berrospi, AR; Kupferman, A; Leibowitz, HM, 1982) |
| "Treatment with NP-siRNAs targeting key scarring genes or an anti-inflammatory steroid reduced corneal haze and SMA mRNA and protein." | 1.40 | Assessment of anti-scarring therapies in ex vivo organ cultured rabbit corneas. ( Gibson, DJ; Lewin, AS; Pi, L; Robinson, P; Schultz, G; Sriram, S; Tuli, S, 2014) |
| "Anterior uveitis was induced in one eye of eight rabbits by subcutaneous injection of Mycobacterium tuberculosis, followed after 10 days with intravitreal challenge." | 1.31 | Evaluation of therapeutic effectiveness using MR imaging in a rabbit model of anterior uveitis. ( Freddo, TF; Goode, ST; Kolodny, NH; Ryan, W, 2002) |
| " These results suggest that either salt of prednisolone, when combined with ciprofloxacin, reduces ocular inflammation without affecting the antimicrobial efficacy of the antibiotic." | 1.29 | Prednisolone acetate or prednisolone phosphate concurrently administered with ciprofloxacin for the therapy of experimental Pseudomonas aeruginosa keratitis. ( Callegan, MC; Engel, LS; Hill, JM; Hobden, JA; O'Callaghan, RJ, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.45) | 18.7374 |
| 1990's | 4 (13.79) | 18.2507 |
| 2000's | 8 (27.59) | 29.6817 |
| 2010's | 14 (48.28) | 24.3611 |
| 2020's | 2 (6.90) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Cheng, YH | 1 |
| Chang, YF | 1 |
| Ko, YC | 1 |
| Liu, CJ | 1 |
| Wei, J | 3 |
| Gao, J | 1 |
| Ding, X | 1 |
| Wu, YT | 1 |
| Truong, TN | 2 |
| Tam, C | 1 |
| Mendoza, MN | 2 |
| Zhu, L | 1 |
| Evans, DJ | 1 |
| Fleiszig, SMJ | 1 |
| Semsettin, B | 1 |
| Sinan, E | 1 |
| Nigar, V | 1 |
| Beyazyıldız, E | 1 |
| Acar, U | 1 |
| Beyazyıldız, Ö | 1 |
| Pınarlı, FA | 1 |
| Albayrak, A | 1 |
| Uğurlu, N | 1 |
| Tiryaki, M | 1 |
| Delibaşi, T | 1 |
| Sriram, S | 1 |
| Gibson, DJ | 1 |
| Robinson, P | 1 |
| Pi, L | 1 |
| Tuli, S | 1 |
| Lewin, AS | 1 |
| Schultz, G | 1 |
| Eriş, E | 1 |
| Yüksel, N | 1 |
| Pirhan, D | 1 |
| Karadenizli, A | 1 |
| Aslan, M | 1 |
| Gacar, G | 1 |
| Erman, G | 1 |
| Subaş, C | 1 |
| Uzuner, H | 1 |
| Yldz, DK | 1 |
| Karaöz, E | 1 |
| Gerometta, R | 3 |
| Podos, SM | 3 |
| Danias, J | 2 |
| Candia, OA | 3 |
| Millar, JC | 1 |
| Kaufman, PL | 1 |
| Guan, XY | 1 |
| Han, D | 1 |
| Berger, EA | 1 |
| McClellan, SA | 1 |
| Barrett, RP | 1 |
| Hazlett, LD | 1 |
| Altmann, S | 1 |
| Brandt, CR | 1 |
| Murphy, CJ | 1 |
| Patnaikuni, R | 1 |
| Takla, T | 1 |
| Toomey, M | 1 |
| Nesbit, B | 1 |
| McIntyre, K | 1 |
| Covert, J | 1 |
| Dubielzig, R | 1 |
| Leatherberry, G | 1 |
| Adkins, E | 1 |
| Kodihalli, S | 1 |
| Hos, D | 1 |
| Saban, DR | 1 |
| Bock, F | 1 |
| Regenfuss, B | 1 |
| Onderka, J | 1 |
| Masli, S | 1 |
| Cursiefen, C | 1 |
| Ge, Y | 1 |
| Ren, L | 1 |
| Panagis, L | 1 |
| Mittag, TW | 1 |
| Ang, M | 1 |
| Yan, P | 1 |
| Zhen, M | 1 |
| Foo, S | 1 |
| Venkatraman, SS | 1 |
| Wong, TT | 1 |
| Holzer, MP | 2 |
| Sandoval, HP | 2 |
| Vargas, LG | 2 |
| Kasper, TJ | 2 |
| Vroman, DT | 2 |
| Apple, DJ | 2 |
| Solomon, KD | 2 |
| Lee, EJ | 1 |
| Fleiszig, SM | 1 |
| Bolinder, A | 1 |
| Cameron, K | 1 |
| Faubert, L | 1 |
| Wilson, J | 1 |
| Aramini, J | 1 |
| Hare, J | 1 |
| Ma, ZL | 1 |
| Zhang, W | 1 |
| Gu, XP | 1 |
| Yang, WS | 1 |
| Zeng, YM | 1 |
| Kupferman, A | 1 |
| Berrospi, AR | 1 |
| Leibowitz, HM | 1 |
| Hobden, JA | 1 |
| Engel, LS | 1 |
| Hill, JM | 1 |
| Callegan, MC | 1 |
| O'Callaghan, RJ | 1 |
| Romanowski, EG | 1 |
| Roba, LA | 1 |
| Wiley, L | 1 |
| Araullo-Cruz, T | 1 |
| Gordon, YJ | 1 |
| Kojima, M | 2 |
| Shui, YB | 2 |
| Murano, H | 1 |
| Sasaki, K | 2 |
| Oku, Y | 1 |
| Chai, JJ | 1 |
| Osman, I | 1 |
| Liao, LF | 1 |
| Asakawa, M | 1 |
| Hagiwara, K | 1 |
| Kobayashi, K | 1 |
| Ito, M | 1 |
| Kolodny, NH | 1 |
| Goode, ST | 1 |
| Ryan, W | 1 |
| Freddo, TF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Double-Masked Trial of Topical Dexamethasone 0.1%/Povidone-iodine 0.4% Versus Artificial Tears for Treatment of Viral Conjunctivitis[NCT01481519] | Phase 3 | 100 participants (Anticipated) | Interventional | 2011-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
29 other studies available for prednisolone acetate and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Development of a dual delivery of levofloxacin and prednisolone acetate via PLGA nanoparticles/ thermosensitive chitosan-based hydrogel for postoperative management: An in-vitro and ex-vivo study.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Cell Survival; Cells, Cultured; Chitosan; | 2021 |
Exploring the mechanism of Jieduquyuziyin prescription on systemic lupus erythematosus by GC-MS-based urine metabolomics.
Topics: Animals; Disease Models, Animal; Drugs, Chinese Herbal; Female; Gas Chromatography-Mass Spectrometry | 2018 |
Impact of topical corticosteroid pretreatment on susceptibility of the injured murine cornea to Pseudomonas aeruginosa colonization and infection.
Topics: Administration, Ophthalmic; Animals; Cornea; Corneal Injuries; Corneal Ulcer; Disease Models, Animal | 2019 |
Comparison of the effects of topical cyclosporine a 0.05%, cyclosporine a 2%, epinastine hydrochloride 0.05%, and prednisolone acetate 1% on allergic inflammation in an experimental allergic conjunctivitis model.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Conjunctivitis, Allergic; Cyclosporine; | 2013 |
Comparison of prednisolone acetate and loteprednol etabonate for the treatment of benzalkonium chloride-induced dry eye syndrome in rats.
Topics: Administration, Topical; Androstadienes; Animals; Benzalkonium Compounds; Disease Models, Animal; Dr | 2014 |
Assessment of anti-scarring therapies in ex vivo organ cultured rabbit corneas.
Topics: Actins; Analysis of Variance; Animals; Anti-Inflammatory Agents; Cicatrix; Connective Tissue Growth | 2014 |
Evaluation of Effect of Topical Tacrolimus Treatment on Herpetic Stromal Keratitis in a Rat Model.
Topics: Administration, Topical; Animals; CD3 Complex; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocyte | 2016 |
Steroid-induced ocular hypertension in normal sheep.
Topics: Administration, Topical; Animals; Disease Models, Animal; Glucocorticoids; Intraocular Pressure; Ocu | 2009 |
Suppression of corticosteroid-induced ocular hypertension in sheep by anecortave.
Topics: Administration, Topical; Angiogenesis Inhibitors; Animals; Aqueous Humor; Disease Models, Animal; Fe | 2010 |
Suppression and reduction of corticosteroid-induced ocular hypertension by anecortave in sheep.
Topics: Angiogenesis Inhibitors; Animals; Disease Models, Animal; Glucocorticoids; Intraocular Pressure; Ocu | 2010 |
Role of hypercoagulability in steroid-induced femoral head necrosis in rabbits.
Topics: Animals; Blood Viscosity; Disease Models, Animal; Erythrocyte Aggregation; Femur Head Necrosis; Hepa | 2010 |
VIP promotes resistance in the Pseudomonas aeruginosa-infected cornea by modulating adhesion molecule expression.
Topics: Animals; Cell Adhesion Molecules; Cell Movement; Corneal Ulcer; Disease Models, Animal; Enzyme-Linke | 2010 |
Evaluation of therapeutic interventions for vaccinia virus keratitis.
Topics: Animals; Anti-Inflammatory Agents; Antibodies, Viral; Antiviral Agents; Blindness; Chlorocebus aethi | 2011 |
Suppression of inflammatory corneal lymphangiogenesis by application of topical corticosteroids.
Topics: Administration, Topical; Animals; Cell Culture Techniques; Cell Proliferation; Corneal Neovasculariz | 2011 |
Gene expression changes in steroid-induced IOP elevation in bovine trabecular meshwork.
Topics: Animals; Anti-Inflammatory Agents; Cattle; Computational Biology; Disease Models, Animal; Female; Ge | 2011 |
Evaluation of sustained release of PLC-loaded prednisolone acetate microfilm on postoperative inflammation in an experimental model of glaucoma filtration surgery.
Topics: Animals; Delayed-Action Preparations; Disease Models, Animal; Drug Carriers; Endophthalmitis; Female | 2011 |
Corneal flap complications in refractive surgery: Part 2: postoperative treatments of diffuse lamellar keratitis in an experimental animal model.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Corneal Stroma; Disease Mod | 2003 |
A comparison of invasive and cytotoxic Pseudomonas aeruginosa strain-induced corneal disease responses to therapeutics.
Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Cornea; Corneal Ulcer; Disease Models, Anim | 2003 |
Evaluation of preoperative and postoperative prophylactic regimens for prevention and treatment of diffuse lamellar keratitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cornea; Disease Models, Animal; Drug Evaluation, P | 2004 |
In vivo efficacy study of the anti-inflammatory properties of Surolan.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Ear; Female; Inflam | 2006 |
Effects of intrathecal injection of prednisolone acetate on expression of NR2B subunit and nNOS in spinal cord of rats after chronic compression of dorsal root ganglia.
Topics: Animals; Anti-Inflammatory Agents; Chronic Disease; Disease Models, Animal; Ganglia, Spinal; Immunoh | 2007 |
Fluorometholone acetate. A new ophthalmic derivative of fluorometholone.
Topics: Acetates; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Drug Administration Schedule; F | 1982 |
Prednisolone acetate or prednisolone phosphate concurrently administered with ciprofloxacin for the therapy of experimental Pseudomonas aeruginosa keratitis.
Topics: Animals; Aqueous Humor; Ciprofloxacin; Corneal Ulcer; Disease Models, Animal; Drug Therapy, Combinat | 1993 |
The effects of corticosteroids of adenoviral replication.
Topics: Adenoviridae Infections; Adenoviruses, Human; Animals; Anti-Inflammatory Agents; Conjunctivitis, Vir | 1996 |
Inhibition of steroid-induced cataract in rat eyes by administration of vitamin-E ophthalmic solution.
Topics: Animals; Body Weight; Cataract; Disease Models, Animal; Glucocorticoids; Lens, Crystalline; Light; M | 1996 |
A new steroid-induced cataract model in the rat: long-term prednisolone applications with a minimum of X-irradiation.
Topics: Animals; Blood Glucose; Body Weight; Cataract; Disease Models, Animal; Glucocorticoids; Image Proces | 1996 |
Meriones meridianus and Lagurus lagurus as alternative definitive hosts of Echinococcus multilocularis and E. granulosus.
Topics: Animals; Cricetinae; Disease Models, Animal; Echinococcosis; Echinococcus; Female; Gerbillinae; Inte | 2002 |
Evaluation of therapeutic effectiveness using MR imaging in a rabbit model of anterior uveitis.
Topics: Animals; Anterior Chamber; Anti-Inflammatory Agents; Ciliary Body; Contrast Media; Disease Models, A | 2002 |