Page last updated: 2024-11-07

prednisolone acetate and Cataract

prednisolone acetate has been researched along with Cataract in 29 studies

prednisolone acetate: RN given refers to cpd with locant for acetate group in position 21 & (11 beta)-isomer

Cataract: Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"Difluprednate administered twice a day was at least as effective as prednisolone acetate administered 4 times a day for inflammatory treatment after cataract surgery."9.51Difluprednate 0.05% twice a day vs prednisolone acetate 1% 4 times a day for cataract postsurgical inflammation treatment: noninferiority trial. ( Del Papa, M; Ferroni, C; Ferroni, V; Idiart, C; Kaufer, R; Marino, F; Masseroni, M; Nuñez, M; Passerini, MS; Valvecchia, G; Zaldívar, R, 2022)
"5% with prednisolone acetate suspension (PA) 1% for the treatment of inflammation after cataract surgery in children."9.34Loteprednol etabonate gel 0.5% vs prednisolone acetate suspension 1% for the treatment of inflammation after cataract surgery in children. ( Vittitow, JL; Williams, JI, 2020)
"To evaluate and compare regulation of diabetes mellitus (DM) in dogs with cataracts and well-controlled DM that received an ophthalmic preparation of prednisolone acetate versus diclofenac sodium."9.30Evaluation of diabetes mellitus regulation in dogs treated with ophthalmic preparations of prednisolone acetate versus diclofenac sodium. ( Bello, NM; Fentiman, KE; Huey, JA; KuKanich, KS; Meekins, JM; Rankin, AJ; Schermerhorn, T, 2019)
"To compare the outcomes of congenital cataract surgery using intraoperative intracameral triamcinolone versus postoperative oral prednisolone to modulate ocular inflammation."9.19Outcomes of congenital cataract surgery: intraoperative intracameral triamcinolone injection versus postoperative oral prednisolone. ( Arantes, TE; Nosé, W; Ventura, BV; Ventura, CV; Ventura, LO; Ventura, MC, 2014)
"To investigate the relationship between vitamin E deficiency and prednisolone-induced cataract formation, long-term examination of lens changes was performed in rats under the condition of vitamin E deficiency or supplementation and administration of prednisolone."7.71Low vitamin E level as a subliminal risk factor in a rat model of prednisolone-induced cataract. ( Hockwin, O; Kojima, M; Murano, H; Nagata, M; Sasaki, K; Shui, YB; Takahashi, N, 2002)
"In order to induce experimental steroid cataracts in rat eyes similar morphologically to those seen in human eyes, prednisolone acetate was administered either topically or systemically for 12 months with a low dose of X-irradiation as a cocataractogenic factor."7.69A new steroid-induced cataract model in the rat: long-term prednisolone applications with a minimum of X-irradiation. ( Kojima, M; Sasaki, K; Shui, YB, 1996)
" Safety included evaluation of adverse events."6.82Difluprednate versus prednisolone acetate for inflammation following cataract surgery in pediatric patients: a randomized safety and efficacy study. ( Gedif, K; Lambert, SR; Markwardt, K; O'Halloran, H; Plager, DA; Roarty, J; VanderVeen, D; Wilson, ME, 2016)
"Difluprednate administered twice a day was at least as effective as prednisolone acetate administered 4 times a day for inflammatory treatment after cataract surgery."5.51Difluprednate 0.05% twice a day vs prednisolone acetate 1% 4 times a day for cataract postsurgical inflammation treatment: noninferiority trial. ( Del Papa, M; Ferroni, C; Ferroni, V; Idiart, C; Kaufer, R; Marino, F; Masseroni, M; Nuñez, M; Passerini, MS; Valvecchia, G; Zaldívar, R, 2022)
"5% with prednisolone acetate suspension (PA) 1% for the treatment of inflammation after cataract surgery in children."5.34Loteprednol etabonate gel 0.5% vs prednisolone acetate suspension 1% for the treatment of inflammation after cataract surgery in children. ( Vittitow, JL; Williams, JI, 2020)
"To evaluate and compare regulation of diabetes mellitus (DM) in dogs with cataracts and well-controlled DM that received an ophthalmic preparation of prednisolone acetate versus diclofenac sodium."5.30Evaluation of diabetes mellitus regulation in dogs treated with ophthalmic preparations of prednisolone acetate versus diclofenac sodium. ( Bello, NM; Fentiman, KE; Huey, JA; KuKanich, KS; Meekins, JM; Rankin, AJ; Schermerhorn, T, 2019)
"Eyes having cataract surgery were randomly given an NSAID (bromfenac 0."5.22Effect of postoperative administration of nonsteroidal antiinflammatory drugs and steroids on the conformational changes in wound healing after cataract surgery. ( Choi, EY; Kang, HG; Kim, EK; Kim, TI; Lee, HK, 2016)
"To compare the outcomes of congenital cataract surgery using intraoperative intracameral triamcinolone versus postoperative oral prednisolone to modulate ocular inflammation."5.19Outcomes of congenital cataract surgery: intraoperative intracameral triamcinolone injection versus postoperative oral prednisolone. ( Arantes, TE; Nosé, W; Ventura, BV; Ventura, CV; Ventura, LO; Ventura, MC, 2014)
"In dogs that underwent cataract surgery via phacoemulsification, a full week of topical prednisolone acetate treatment prior to surgery did not decrease postoperative inflammation, compared with commencement of topical prednisolone acetate treatment the evening prior to surgery, and was associated with a greater incidence of postoperative ocular hypertension."5.16Effects of one-week versus one-day preoperative treatment with topical 1% prednisolone acetate in dogs undergoing phacoemulsification. ( Hendrix, DV; McLean, NJ; Vaughn, RK; Ward, DA, 2012)
"To investigate the relationship between vitamin E deficiency and prednisolone-induced cataract formation, long-term examination of lens changes was performed in rats under the condition of vitamin E deficiency or supplementation and administration of prednisolone."3.71Low vitamin E level as a subliminal risk factor in a rat model of prednisolone-induced cataract. ( Hockwin, O; Kojima, M; Murano, H; Nagata, M; Sasaki, K; Shui, YB; Takahashi, N, 2002)
" Initial presentation of the patient was bilateral iridocyclitis, for which he was treated with prednisolone acetate 1% every 2 hours for 6 months."3.70Systemic toxicity of topical and periocular corticosteroid therapy in an 11-year-old male with posterior uveitis. ( Cheng, L; Freeman, WR; Levi, L; Ozerdem, U; Scher, C; Song, MK, 2000)
"In order to induce experimental steroid cataracts in rat eyes similar morphologically to those seen in human eyes, prednisolone acetate was administered either topically or systemically for 12 months with a low dose of X-irradiation as a cocataractogenic factor."3.69A new steroid-induced cataract model in the rat: long-term prednisolone applications with a minimum of X-irradiation. ( Kojima, M; Sasaki, K; Shui, YB, 1996)
" Safety included evaluation of adverse events."2.82Difluprednate versus prednisolone acetate for inflammation following cataract surgery in pediatric patients: a randomized safety and efficacy study. ( Gedif, K; Lambert, SR; Markwardt, K; O'Halloran, H; Plager, DA; Roarty, J; VanderVeen, D; Wilson, ME, 2016)
"To investigate the incidence and outcomes of cystoid macular edema (CME) after Descemet membrane endothelial keratoplasty (DMEK) alone and DMEK combined with cataract surgery (DMEK triple)."1.62Incidence and Outcomes of Cystoid Macular Edema after Descemet Membrane Endothelial Keratoplasty (DMEK) and DMEK Combined with Cataract Surgery. ( Bae, SS; Ching, G; Covello, AT; Holland, S; Iovieno, A; McCarthy, M; Ritenour, R; Yeung, SN, 2021)
" However, chronic use of topical corticosteroids dosed at <3 drops daily seemed to be associated with a lower risk of cataract development relative to eyes receiving higher doses over follow-up in the setting of suppressed uveitis."1.56Risk of Cataract Development among Children with Juvenile Idiopathic Arthritis-Related Uveitis Treated with Topical Corticosteroids. ( Dunn, JP; Jabs, DA; Thorne, JE; Woreta, FA, 2020)
"To analyze the effect of intensified topical steroid therapy after Descemet membrane endothelial keratoplasty combined with cataract surgery (triple-DMEK) on the incidence of postoperative cystoid macular edema (CME)."1.43Intensified Topical Steroids as Prophylaxis for Macular Edema After Posterior Lamellar Keratoplasty Combined With Cataract Surgery. ( Bachmann, BO; Cursiefen, C; Felsch, M; Hoerster, R; Siebelmann, S; Stanzel, TP, 2016)
" However, chronic use of topical corticosteroids dosed at < or = 3 drops daily seemed to be associated with a lower risk of cataract development relative to eyes receiving higher doses over follow-up in the setting of suppressed uveitis."1.36Risk of cataract development among children with juvenile idiopathic arthritis-related uveitis treated with topical corticosteroids. ( Dunn, JP; Jabs, DA; Thorne, JE; Woreta, FA, 2010)
"Data recorded were visual acuity (VA), recurrences and surgical complications."1.36[Pars plana vitrectomy as anti-inflammatory therapy for intermediate uveitis in children]. ( Arruabarrena, C; Contreras, I; Figueroa, MS; García-Pérez, JL; Gil-Cazorla, R; Noval, S; Sales, M, 2010)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.90)18.7374
1990's3 (10.34)18.2507
2000's7 (24.14)29.6817
2010's11 (37.93)24.3611
2020's6 (20.69)2.80

Authors

AuthorsStudies
Valvecchia, G1
Kaufer, R1
Ferroni, C1
Zaldívar, R1
Masseroni, M1
Idiart, C1
Ferroni, V1
Marino, F1
Nuñez, M1
Del Papa, M1
Passerini, MS1
Hovanesian, JA1
Donnenfeld, ED1
Rankin, AJ1
KuKanich, KS1
Schermerhorn, T1
Bello, NM1
Huey, JA1
Fentiman, KE1
Meekins, JM1
Thorne, JE2
Woreta, FA2
Dunn, JP2
Jabs, DA2
Vittitow, JL1
Williams, JI1
Ching, G1
Covello, AT1
Bae, SS1
Holland, S1
McCarthy, M1
Ritenour, R1
Iovieno, A1
Yeung, SN1
Grzybowski, A1
Kanclerz, P1
Lytvynchuk, L1
Ventura, MC1
Ventura, BV1
Ventura, CV1
Ventura, LO1
Arantes, TE1
Nosé, W1
Hoerster, R1
Stanzel, TP1
Bachmann, BO1
Siebelmann, S1
Felsch, M1
Cursiefen, C1
Wilson, ME2
O'Halloran, H2
VanderVeen, D2
Roarty, J2
Plager, DA2
Markwardt, K1
Gedif, K1
Lambert, SR2
Ranjan, A1
Murthy, SI1
Rathi, VM1
Sangwan, VS1
Kaur, S1
Sukhija, J1
Choi, EY1
Kang, HG1
Kim, TI1
Kim, EK1
Lee, HK1
Figueroa, MS1
Noval, S1
Contreras, I1
Arruabarrena, C1
García-Pérez, JL1
Sales, M1
Gil-Cazorla, R1
McLean, NJ1
Ward, DA1
Hendrix, DV1
Vaughn, RK1
Lam, LA1
Lowder, CY1
Baerveldt, G1
Smith, SD1
Traboulsi, EI1
Till, JS1
Sowka, J1
Vollmer, L1
Falco, L1
Lam, DS1
Leung, DY1
Tham, CC1
Li, FC1
Kwong, YY1
Chiu, TY1
Fan, DS1
Nishigori, H1
Lee, JW1
Iwamoto, Y1
Hayashi, R1
Maruyama, K1
Iwatsuru, M1
Kojima, M4
Shui, YB4
Murano, H2
Sasaki, K3
Vrensen, GF1
Ozerdem, U1
Levi, L1
Cheng, L1
Song, MK1
Scher, C1
Freeman, WR1
Caprioli, J1
Samson, CM1
Foster, CS1
Araie, M1
Rockwood, EJ1
Nagata, M1
Hockwin, O1
Takahashi, N1
Mondino, BJ1
Farley, MK1
Aizuss, DH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The D3 Study: Drug Delivery vs Drops - A Prospective Clinical Study Evaluating Dexycu vs Prednisolone Acetate 1% in Controlling Post-operative Pain and Inflammation in Patients Undergoing Sequential Cataract Surgery[NCT04273282]Phase 431 participants (Actual)Interventional2019-12-16Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

9 trials available for prednisolone acetate and Cataract

ArticleYear
Difluprednate 0.05% twice a day vs prednisolone acetate 1% 4 times a day for cataract postsurgical inflammation treatment: noninferiority trial.
    Journal of cataract and refractive surgery, 2022, 07-01, Volume: 48, Issue:7

    Topics: Cataract; Eye Diseases; Fluprednisolone; Humans; Inflammation; Phacoemulsification; Postoperative Co

2022
Intracameral dexamethasone 9% vs prednisolone acetate 1% in controlling postoperative pain and inflammation in patients undergoing cataract surgery.
    Journal of cataract and refractive surgery, 2022, 08-01, Volume: 48, Issue:8

    Topics: Cataract; Cataract Extraction; Dexamethasone; Humans; Inflammation; Moxifloxacin; Ophthalmic Solutio

2022
Evaluation of diabetes mellitus regulation in dogs treated with ophthalmic preparations of prednisolone acetate versus diclofenac sodium.
    American journal of veterinary research, 2019, Volume: 80, Issue:12

    Topics: Animals; Cataract; Diabetes Complications; Diabetes Mellitus; Diclofenac; Dog Diseases; Dogs; Double

2019
Loteprednol etabonate gel 0.5% vs prednisolone acetate suspension 1% for the treatment of inflammation after cataract surgery in children.
    Journal of cataract and refractive surgery, 2020, Volume: 46, Issue:8

    Topics: Androstadienes; Cataract; Child; Double-Blind Method; Humans; Inflammation; Intraocular Pressure; Lo

2020
Outcomes of congenital cataract surgery: intraoperative intracameral triamcinolone injection versus postoperative oral prednisolone.
    Journal of cataract and refractive surgery, 2014, Volume: 40, Issue:4

    Topics: Administration, Oral; Anterior Eye Segment; Cataract; Cataract Extraction; Cornea; Corneal Pachymetr

2014
Difluprednate versus prednisolone acetate for inflammation following cataract surgery in pediatric patients: a randomized safety and efficacy study.
    Eye (London, England), 2016, Volume: 30, Issue:9

    Topics: Administration, Topical; Aphakia, Postcataract; Cataract; Cataract Extraction; Child, Preschool; Dou

2016
Effect of postoperative administration of nonsteroidal antiinflammatory drugs and steroids on the conformational changes in wound healing after cataract surgery.
    Journal of cataract and refractive surgery, 2016, Volume: 42, Issue:12

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzophenones; Bromobenzenes; Cataract; Cataract Extraction

2016
Effects of one-week versus one-day preoperative treatment with topical 1% prednisolone acetate in dogs undergoing phacoemulsification.
    Journal of the American Veterinary Medical Association, 2012, Mar-01, Volume: 240, Issue:5

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Cataract; Dog Diseases; Dogs; Drug Admin

2012
Randomized trial of early phacoemulsification versus peripheral iridotomy to prevent intraocular pressure rise after acute primary angle closure.
    Ophthalmology, 2008, Volume: 115, Issue:7

    Topics: Acute Disease; Aged; Antihypertensive Agents; Cataract; Female; Follow-Up Studies; Glaucoma, Angle-C

2008

Other Studies

20 other studies available for prednisolone acetate and Cataract

ArticleYear
Risk of Cataract Development among Children with Juvenile Idiopathic Arthritis-Related Uveitis Treated with Topical Corticosteroids.
    Ophthalmology, 2020, Volume: 127, Issue:4S

    Topics: Administration, Ophthalmic; Adolescent; Adult; Arthritis, Juvenile; Cataract; Child; Child, Preschoo

2020
Incidence and Outcomes of Cystoid Macular Edema after Descemet Membrane Endothelial Keratoplasty (DMEK) and DMEK Combined with Cataract Surgery.
    Current eye research, 2021, Volume: 46, Issue:5

    Topics: Administration, Ophthalmic; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Anti-Inflammatory Age

2021
Methods for achieving low endophthalmitis rates in phacoemulsification cataract surgery.
    Acta ophthalmologica, 2020, Volume: 98, Issue:1

    Topics: Benzeneacetamides; Cataract; Endophthalmitis; Finland; Humans; Levofloxacin; Phacoemulsification; Ph

2020
Intensified Topical Steroids as Prophylaxis for Macular Edema After Posterior Lamellar Keratoplasty Combined With Cataract Surgery.
    American journal of ophthalmology, 2016, Volume: 163

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Cataract; Corneal Diseases; Descemet Stripp

2016
Acute Bilateral Toxic Endotheliitis Following Alcohol Consumption.
    Ocular immunology and inflammation, 2018, Volume: 26, Issue:2

    Topics: Acute Disease; Adult; Alcohol Drinking; Anti-Bacterial Agents; Cataract; Cataract Extraction; Cornea

2018
Difluprednate versus prednisolone acetate for inflammation following cataract surgery in pediatric patients: a randomized safety and efficacy study.
    Eye (London, England), 2017, Volume: 31, Issue:3

    Topics: Anti-Inflammatory Agents; Cataract; Cataract Extraction; Child; Double-Blind Method; Fluprednisolone

2017
Difluprednate versus prednisolone acetate for inflammation following cataract surgery in pediatric patients: a randomized safety and efficacy study.
    Eye (London, England), 2017, Volume: 31, Issue:3

    Topics: Anti-Inflammatory Agents; Cataract; Cataract Extraction; Child; Double-Blind Method; Fluprednisolone

2017
Risk of cataract development among children with juvenile idiopathic arthritis-related uveitis treated with topical corticosteroids.
    Ophthalmology, 2010, Volume: 117, Issue:7

    Topics: Administration, Topical; Adolescent; Adult; Arthritis, Juvenile; Cataract; Child; Child, Preschool;

2010
[Pars plana vitrectomy as anti-inflammatory therapy for intermediate uveitis in children].
    Archivos de la Sociedad Espanola de Oftalmologia, 2010, Volume: 85, Issue:12

    Topics: Adolescent; Anti-Inflammatory Agents; Cataract; Child; Child, Preschool; Combined Modality Therapy;

2010
Surgical management of cataracts in children with juvenile rheumatoid arthritis-associated uveitis.
    American journal of ophthalmology, 2003, Volume: 135, Issue:6

    Topics: Administration, Topical; Anti-Inflammatory Agents; Arthritis, Juvenile; Capsulorhexis; Cataract; Chi

2003
Collamer intraocular lens implantation with active uveitis.
    Journal of cataract and refractive surgery, 2003, Volume: 29, Issue:12

    Topics: Cataract; Female; Glucocorticoids; Humans; Iritis; Laser Therapy; Lens Capsule, Crystalline; Lens Im

2003
Rapid onset phacolysis.
    Optometry (St. Louis, Mo.), 2004, Volume: 75, Issue:9

    Topics: Autoantibodies; Autoantigens; Cataract; Cataract Extraction; Crystallins; Female; Glaucoma; Glucocor

2004
Alteration of hepatic lipidperoxide levels during cataract formation caused by glucocorticoids in developing chick embryos.
    Life sciences, 1984, Aug-27, Volume: 35, Issue:9

    Topics: Animals; Cataract; Chick Embryo; Dexamethasone; Glucocorticoids; Hydrocortisone; Lipid Peroxides; Li

1984
Inhibition of steroid-induced cataract in rat eyes by administration of vitamin-E ophthalmic solution.
    Ophthalmic research, 1996, Volume: 28 Suppl 2

    Topics: Animals; Body Weight; Cataract; Disease Models, Animal; Glucocorticoids; Lens, Crystalline; Light; M

1996
A new steroid-induced cataract model in the rat: long-term prednisolone applications with a minimum of X-irradiation.
    Ophthalmic research, 1996, Volume: 28 Suppl 2

    Topics: Animals; Blood Glucose; Body Weight; Cataract; Disease Models, Animal; Glucocorticoids; Image Proces

1996
Experimentally induced steroid cataract in the rat: a scanning electron microscopic study.
    Survey of ophthalmology, 1997, Volume: 42 Suppl 1

    Topics: Administration, Topical; Animals; Cataract; Glucocorticoids; Lens, Crystalline; Male; Microscopy, El

1997
Systemic toxicity of topical and periocular corticosteroid therapy in an 11-year-old male with posterior uveitis.
    American journal of ophthalmology, 2000, Volume: 130, Issue:2

    Topics: Acanthosis Nigricans; Administration, Topical; Anti-Inflammatory Agents; Cataract; Child; Cushing Sy

2000
Uveitis and glaucoma.
    Journal of glaucoma, 2000, Volume: 9, Issue:6

    Topics: Antihypertensive Agents; Cataract; Cataract Extraction; Cyclopentolate; Drug Therapy, Combination; F

2000
Low vitamin E level as a subliminal risk factor in a rat model of prednisolone-induced cataract.
    Investigative ophthalmology & visual science, 2002, Volume: 43, Issue:4

    Topics: Animals; Body Weight; Cataract; Glucocorticoids; Lens, Crystalline; Male; Prednisolone; Rats; Rats,

2002
Sectorial corneal infiltrates and pannus in herpes zoster ophthalmicus.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1986, Volume: 224, Issue:3

    Topics: Adolescent; Cataract; Cataract Extraction; Cornea; Corneal Transplantation; Herpes Zoster Ophthalmic

1986