Page last updated: 2024-09-03

pre 084 and Amyotrophic Lateral Sclerosis

pre 084 has been researched along with Amyotrophic Lateral Sclerosis in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bigini, P; Bontempi, L; Collina, S; Curti, D; Manzo, A; Petese, A; Peviani, M; Rossi, D; Salmona, M; Salvaneschi, E1
Del Valle, J; Mancuso, R; Morell, M; Navarro, X; Osta, R; Pallás, M1
Casas, C; Mancuso, R; Navarro, X; Oliván, S; Osta, R; Rando, A1

Other Studies

3 other study(ies) available for pre 084 and Amyotrophic Lateral Sclerosis

ArticleYear
Neuroprotective effects of the Sigma-1 receptor (S1R) agonist PRE-084, in a mouse model of motor neuron disease not linked to SOD1 mutation.
    Neurobiology of disease, 2014, Volume: 62

    Topics: Age Factors; Amyotrophic Lateral Sclerosis; Animals; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Female; Locomotion; Male; Mice; Mice, Transgenic; Morpholines; Motor Neuron Disease; Motor Neurons; Mutation; Neuroglia; Neuroprotective Agents; Receptors, sigma; Sigma-1 Receptor; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1

2014
Lack of synergistic effect of resveratrol and sigma-1 receptor agonist (PRE-084) in SOD1G⁹³A ALS mice: overlapping effects or limited therapeutic opportunity?
    Orphanet journal of rare diseases, 2014, May-21, Volume: 9

    Topics: Adenylate Kinase; Amyotrophic Lateral Sclerosis; Animals; Drug Synergism; Mice; Mice, Transgenic; Morpholines; Neural Conduction; Phosphorylation; Protein Kinase C; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Resveratrol; Rotarod Performance Test; Sigma-1 Receptor; Sirtuin 1; Stilbenes; Superoxide Dismutase

2014
Sigma-1R agonist improves motor function and motoneuron survival in ALS mice.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2012, Volume: 9, Issue:4

    Topics: Amyotrophic Lateral Sclerosis; Animals; Blotting, Western; Cell Survival; Disease Models, Animal; Electrophysiology; Female; Humans; Immunohistochemistry; Male; Mice; Mice, Transgenic; Morpholines; Motor Activity; Motor Neurons; Neuroprotective Agents; Receptors, sigma; Sigma-1 Receptor; Superoxide Dismutase; Superoxide Dismutase-1

2012