prazosin has been researched along with Ventricular Dysfunction, Left in 7 studies
Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.
Ventricular Dysfunction, Left: A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The role of alpha(1)-adrenergic stimulation in myocardial TNF-alpha expression and depressed cardiac function after HS/R was assessed by treatment with the alpha(1)-adrenergic inhibitor, prazosin hydrochloride (1 mg/kg ip), for 1 h before the onset of hemorrhage." | 3.71 | Hemorrhage-induced alpha-adrenergic signaling results in myocardial TNF-alpha expression and contractile dysfunction. ( Klein, LV; Lindsay, TF; Marshall, JG; Nicholson, S; Rubin, BB; Shahani, R; Walker, PM, 2001) |
| "[3H]Prazosin binding was determined in arterial segments of Wistar-Kyoto rats (WKY), and of Wistar rats 5 weeks after myocardial infarction (MI) or sham operation (SHAM)." | 3.69 | Alpha 1-adrenoceptor subtypes in rat aorta and mesenteric small arteries are preserved during left ventricular dysfunction post-myocardial infarction. ( DeMey, JG; Janssen, GM; Stassen, FR; Willemsen, MJ, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Abdel Baseer, KA | 1 |
| Aboelela, MG | 1 |
| Qubaisy, HM | 1 |
| Isabelle, M | 1 |
| Monteil, C | 1 |
| Moritz, F | 1 |
| Dautreaux, B | 1 |
| Henry, JP | 1 |
| Richard, V | 1 |
| Mulder, P | 1 |
| Thuillez, C | 1 |
| Stassen, FR | 1 |
| Willemsen, MJ | 1 |
| Janssen, GM | 1 |
| DeMey, JG | 1 |
| Grupp, IL | 1 |
| Lorenz, JN | 1 |
| Walsh, RA | 1 |
| Boivin, GP | 1 |
| Rindt, H | 1 |
| Adigun, AQ | 1 |
| Ajayi, OE | 1 |
| Sofowora, GG | 1 |
| Ajayi, AA | 1 |
| Cohn, JN | 1 |
| Shahani, R | 1 |
| Klein, LV | 1 |
| Marshall, JG | 1 |
| Nicholson, S | 1 |
| Rubin, BB | 1 |
| Walker, PM | 1 |
| Lindsay, TF | 1 |
1 review available for prazosin and Ventricular Dysfunction, Left
| Article | Year |
|---|---|
Left ventricle and arteries: structure, function, hormones, and disease.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Arginine Vasopressin; Dr | 2001 |
1 trial available for prazosin and Ventricular Dysfunction, Left
| Article | Year |
|---|---|
Vasodilator therapy of hypertensive acute left ventricular failure: comparison of captopril-prazosin with hydralazine-isosorbide dinitrate.
Topics: Adult; Antihypertensive Agents; Captopril; Drug Therapy, Combination; Female; Humans; Hydralazine; H | 1998 |
5 other studies available for prazosin and Ventricular Dysfunction, Left
| Article | Year |
|---|---|
Echocardiographic Evaluation of the Response to Prazosin Treatment in Scorpion Sting.
Topics: Adolescent; Child; Echocardiography; Humans; Male; Prazosin; Prospective Studies; Scorpion Stings; V | 2021 |
Role of alpha1-adrenoreceptors in cocaine-induced NADPH oxidase expression and cardiac dysfunction.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cardiomegaly; Cardiomyopathies; Co | 2005 |
Alpha 1-adrenoceptor subtypes in rat aorta and mesenteric small arteries are preserved during left ventricular dysfunction post-myocardial infarction.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Calcium Channel Blockers; Dihydropyridines; In Vitro T | 1997 |
Overexpression of alpha1B-adrenergic receptor induces left ventricular dysfunction in the absence of hypertrophy.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Blood Pressure; Calcium; Cardiomegaly; Cells, Cult | 1998 |
Hemorrhage-induced alpha-adrenergic signaling results in myocardial TNF-alpha expression and contractile dysfunction.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Hemorrhage; Male; Myocardial Contr | 2001 |