Page last updated: 2024-11-03

prazosin and Urinary Retention

prazosin has been researched along with Urinary Retention in 16 studies

Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.

Urinary Retention: Inability to empty the URINARY BLADDER with voiding (URINATION).

Research Excerpts

ExcerptRelevanceReference
"This prospective randomized double-blinded clinical trial was designed to explore the effects of amlodipine and the combination of amlodipine with terazosin in improving postvoid residual (PVR) in patients with lower urinary tract symptoms (LUTS) and concomitant hypertension."9.14[Amlodipine combined with terazosin reduces postvoid residual and the risk of acute urinary retention]. ( Fang, J; Li, YL; Liu, HP; Qin, XH; Xu, XP; Yang, C; Zhang, X, 2009)
"Terazosin, a selective, long-acting alpha 1-adrenergic blocker, was evaluated in 44 men with benign prostatic hyperplasia."9.07Efficacy of terazosin in patients with benign prostatic hyperplasia. ( Laddu, A; Matzkin, H; Rangel, MC; Soloway, MS, 1992)
"Acute urinary retention is a frequent complication following inguinal hernia repair."6.68A placebo controlled double blind study using perioperative prazosin in the prevention of urinary retention following inguinal hernia repair. ( Carmalt, HL; Woo, HH, 1995)
"This prospective randomized double-blinded clinical trial was designed to explore the effects of amlodipine and the combination of amlodipine with terazosin in improving postvoid residual (PVR) in patients with lower urinary tract symptoms (LUTS) and concomitant hypertension."5.14[Amlodipine combined with terazosin reduces postvoid residual and the risk of acute urinary retention]. ( Fang, J; Li, YL; Liu, HP; Qin, XH; Xu, XP; Yang, C; Zhang, X, 2009)
"Terazosin, a selective, long-acting alpha 1-adrenergic blocker, was evaluated in 44 men with benign prostatic hyperplasia."5.07Efficacy of terazosin in patients with benign prostatic hyperplasia. ( Laddu, A; Matzkin, H; Rangel, MC; Soloway, MS, 1992)
"To evaluate the use and problems of alpha-receptor blockade with prazosin among patients in Nigeria with benign prostatic hyperplasia (BPH) who face a prolonged wait for a prostatectomy."3.69alpha-receptor blockade for benign prostatic hyperplasia: uses and problems in a developing country. ( Ogbonna, BC; Okeahialam, BN; Ramyil, VM, 1997)
"Once-daily dosing of TAM after breakfast at a fixed dose level (0."2.69A double-blind comparison of terazosin and tamsulosin on their differential effects on ambulatory blood pressure and nocturnal orthostatic stress testing. ( de Mey, C; McEwen, J; Michel, MC; Moreland, T, 1998)
"Acute urinary retention is a frequent complication following inguinal hernia repair."2.68A placebo controlled double blind study using perioperative prazosin in the prevention of urinary retention following inguinal hernia repair. ( Carmalt, HL; Woo, HH, 1995)
"Alternative treatments for benign prostatic hyperplasia (BPH) are the source of much discussion at present."2.67Comparative study of selective alpha 1-adrenoceptor blockade versus surgery in the treatment of prostatic obstruction. ( Chapple, CR; Milroy, EJ; Noble, JG, 1993)
"Urinary retention is the most common complication after anorectal surgery, with rates as high as 52 percent reported."2.67Does alpha sympathetic blockade prevent urinary retention following anorectal surgery? ( Cataldo, PA; Senagore, AJ, 1991)
" Only one of these could be managed satisfactorily by long-term administration of prazosin, carbachol and antibiotics, and the others had to be euthanased."1.30Idiopathic detrusor-urethral dyssynergia in dogs: a retrospective analysis of 22 cases. ( Díaz Espiñeira, MM; Nickel, RF; Viehoff, FW, 1998)
"Thus, functional bladder neck obstruction was considered to be responsible for obstructive voiding in these patients."1.29Functional bladder neck obstruction: a rare cause of renal failure. ( Banerjee, GK; Bhandari, M; Goel, MC; Kapoor, R; Kumar, A; Mishra, VK, 1995)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (56.25)18.2507
2000's4 (25.00)29.6817
2010's3 (18.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, KH1
Aulakh, KS1
Liu, C1
Patel, DN1
Felder, SI1
Luu, M1
Daskivich, TJ1
N Zaghiyan, K1
Fleshner, P1
Haagsman, AN1
Kummeling, A1
Moes, ME1
Mesu, SJ1
Kirpensteijn, J1
Yang, C1
Li, YL1
Fang, J1
Zhang, X1
Liu, HP1
Qin, XH1
Xu, XP1
Abeygunasekera, AM1
de Silva, S1
Gurusingha, A1
Wijeratne, S1
Merrick, GS1
Butler, WM1
Wallner, KE1
Lief, JH1
Galbreath, RW1
Chapple, CR1
Noble, JG1
Milroy, EJ1
Kumar, A1
Banerjee, GK1
Goel, MC1
Mishra, VK1
Kapoor, R1
Bhandari, M1
Woo, HH1
Carmalt, HL1
Ogbonna, BC1
Okeahialam, BN1
Ramyil, VM1
de Mey, C1
Michel, MC1
McEwen, J1
Moreland, T1
Díaz Espiñeira, MM1
Viehoff, FW1
Nickel, RF1
Miekos, E1
Trzepizur, Z1
Rózanski, W1
Boniecki, R1
Kusnierz, J1
Jablonowski, Z1
Zydek, C1
Matzkin, H1
Soloway, MS1
Rangel, MC1
Laddu, A1
Petersen, MS1
Collins, DN1
Selakovich, WG1
Finkbeiner, AE1
Cataldo, PA1
Senagore, AJ1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Optimal Duration of Urinary Catheterization After Total Mesorectal Excision[NCT04359069]176 participants (Anticipated)Interventional2020-10-01Recruiting
Acute Urinary Retention After Early, Medium or Late Removal of the Urinary Catheter in Rectal Cancer Surgery. RAOREC Study[NCT04751149]143 participants (Anticipated)Interventional2019-05-01Recruiting
Prospective Study Investigating Optimal Duration of Indwelling Urinary Catheter Following Infraperitoneal Colorectal Surgery and Role of Postoperative Alpha Blockade[NCT01923129]142 participants (Actual)Interventional2012-11-30Completed
Prophylactic Tamsulosin in Prevention of Post-operative Urinary Retention in Men After Transanal Endoscopic Microsurgery: A Multicenter Randomized, Double-blind, Placebo-controlled Clinical Trial[NCT03314025]Phase 2158 participants (Anticipated)Interventional2017-10-06Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants With a Symptomatic Urinary Tract Infection

Urinary tract infection defined as symptomatic urinary complaints such as dysuria, with urinalysis consistent with infection. (NCT01923129)
Timeframe: During 1 week of hospitalization (prior to discharge)

InterventionParticipants (Count of Participants)
24 Hour Postop Catheter Removal0
72 Hour Postoperative Catheter Removal8

Number of Participants With Acute Urinary Retention

Acute urinary retention will be defined as catheter discontinuation with inability to void 6 hours post-removal, or void with post-void residual greater than 200 cc of urine. (NCT01923129)
Timeframe: Postoperative day 1 or postpoperative 3 depending on group randomization

InterventionParticipants (Count of Participants)
24 Hour Postop Catheter Removal6
72 Hour Postoperative Catheter Removal7

Trials

9 trials available for prazosin and Urinary Retention

ArticleYear
Early Urinary Catheter Removal Following Pelvic Colorectal Surgery: A Prospective, Randomized, Noninferiority Trial.
    Diseases of the colon and rectum, 2018, Volume: 61, Issue:10

    Topics: Acute Disease; Adrenergic alpha-1 Receptor Antagonists; Adult; Colorectal Surgery; Device Removal; F

2018
Early Urinary Catheter Removal Following Pelvic Colorectal Surgery: A Prospective, Randomized, Noninferiority Trial.
    Diseases of the colon and rectum, 2018, Volume: 61, Issue:10

    Topics: Acute Disease; Adrenergic alpha-1 Receptor Antagonists; Adult; Colorectal Surgery; Device Removal; F

2018
Early Urinary Catheter Removal Following Pelvic Colorectal Surgery: A Prospective, Randomized, Noninferiority Trial.
    Diseases of the colon and rectum, 2018, Volume: 61, Issue:10

    Topics: Acute Disease; Adrenergic alpha-1 Receptor Antagonists; Adult; Colorectal Surgery; Device Removal; F

2018
Early Urinary Catheter Removal Following Pelvic Colorectal Surgery: A Prospective, Randomized, Noninferiority Trial.
    Diseases of the colon and rectum, 2018, Volume: 61, Issue:10

    Topics: Acute Disease; Adrenergic alpha-1 Receptor Antagonists; Adult; Colorectal Surgery; Device Removal; F

2018
Early Urinary Catheter Removal Following Pelvic Colorectal Surgery: A Prospective, Randomized, Noninferiority Trial.
    Diseases of the colon and rectum, 2018, Volume: 61, Issue:10

    Topics: Acute Disease; Adrenergic alpha-1 Receptor Antagonists; Adult; Colorectal Surgery; Device Removal; F

2018
Early Urinary Catheter Removal Following Pelvic Colorectal Surgery: A Prospective, Randomized, Noninferiority Trial.
    Diseases of the colon and rectum, 2018, Volume: 61, Issue:10

    Topics: Acute Disease; Adrenergic alpha-1 Receptor Antagonists; Adult; Colorectal Surgery; Device Removal; F

2018
Early Urinary Catheter Removal Following Pelvic Colorectal Surgery: A Prospective, Randomized, Noninferiority Trial.
    Diseases of the colon and rectum, 2018, Volume: 61, Issue:10

    Topics: Acute Disease; Adrenergic alpha-1 Receptor Antagonists; Adult; Colorectal Surgery; Device Removal; F

2018
Early Urinary Catheter Removal Following Pelvic Colorectal Surgery: A Prospective, Randomized, Noninferiority Trial.
    Diseases of the colon and rectum, 2018, Volume: 61, Issue:10

    Topics: Acute Disease; Adrenergic alpha-1 Receptor Antagonists; Adult; Colorectal Surgery; Device Removal; F

2018
Early Urinary Catheter Removal Following Pelvic Colorectal Surgery: A Prospective, Randomized, Noninferiority Trial.
    Diseases of the colon and rectum, 2018, Volume: 61, Issue:10

    Topics: Acute Disease; Adrenergic alpha-1 Receptor Antagonists; Adult; Colorectal Surgery; Device Removal; F

2018
[Amlodipine combined with terazosin reduces postvoid residual and the risk of acute urinary retention].
    Zhonghua nan ke xue = National journal of andrology, 2009, Volume: 15, Issue:5

    Topics: Adrenergic alpha-Antagonists; Aged; Amlodipine; Antihypertensive Agents; Double-Blind Method; Drug T

2009
Prophylactic versus therapeutic alpha-blockers after permanent prostate brachytherapy.
    Urology, 2002, Volume: 60, Issue:4

    Topics: Adenocarcinoma; Adrenergic alpha-Antagonists; Biopsy; Brachytherapy; Doxazosin; Follow-Up Studies; H

2002
Comparative study of selective alpha 1-adrenoceptor blockade versus surgery in the treatment of prostatic obstruction.
    British journal of urology, 1993, Volume: 72, Issue:5 Pt 2

    Topics: Aged; Aged, 80 and over; Double-Blind Method; Humans; Male; Middle Aged; Prazosin; Prostatectomy; Pr

1993
A placebo controlled double blind study using perioperative prazosin in the prevention of urinary retention following inguinal hernia repair.
    International urology and nephrology, 1995, Volume: 27, Issue:5

    Topics: Acute Disease; Administration, Oral; Adrenergic alpha-Antagonists; Aged; Blood Pressure; Double-Blin

1995
A double-blind comparison of terazosin and tamsulosin on their differential effects on ambulatory blood pressure and nocturnal orthostatic stress testing.
    European urology, 1998, Volume: 33, Issue:5

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Blood Pressure; Blood Pressure Moni

1998
The efficacy of terazosin for treating benign prostatic hyperplasia: a multicentre clinical trial.
    BJU international, 2002, Volume: 89, Issue:7

    Topics: Adrenergic alpha-Antagonists; Dose-Response Relationship, Drug; Humans; Male; Middle Aged; Prazosin;

2002
Efficacy of terazosin in patients with benign prostatic hyperplasia.
    European urology, 1992, Volume: 21, Issue:2

    Topics: Adrenergic alpha-Antagonists; Aged; Drug Administration Schedule; Drug Evaluation; Humans; Male; Pra

1992
Does alpha sympathetic blockade prevent urinary retention following anorectal surgery?
    Diseases of the colon and rectum, 1991, Volume: 34, Issue:12

    Topics: Anal Canal; Chi-Square Distribution; Double-Blind Method; Humans; Pain, Postoperative; Postoperative

1991

Other Studies

7 other studies available for prazosin and Urinary Retention

ArticleYear
Retrospective evaluation of prazosin and diazepam after thoracolumbar hemilaminectomy in dogs.
    Veterinary journal (London, England : 1997), 2019, Volume: 253

    Topics: Adjuvants, Anesthesia; Animals; Diazepam; Dog Diseases; Dogs; Female; Intervertebral Disc Displaceme

2019
Comparison of terazosin and prazosin for treatment of vesico-urethral reflex dyssynergia in dogs.
    The Veterinary record, 2013, Jul-13, Volume: 173, Issue:2

    Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Dog Diseases; Dogs; Male; Prazosin; Treatment Outc

2013
Management of men with a first episode of acute urinary retention due to benign prostatic enlargement.
    The Ceylon medical journal, 2001, Volume: 46, Issue:4

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Humans; Male; Middle Aged; Prazosin; Prospect

2001
Functional bladder neck obstruction: a rare cause of renal failure.
    The Journal of urology, 1995, Volume: 154, Issue:1

    Topics: Adult; Catheters, Indwelling; Creatinine; Electromyography; Female; Follow-Up Studies; Humans; Kidne

1995
alpha-receptor blockade for benign prostatic hyperplasia: uses and problems in a developing country.
    British journal of urology, 1997, Volume: 79, Issue:1

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Heart Diseases; Humans; Hypertension; Male; M

1997
Idiopathic detrusor-urethral dyssynergia in dogs: a retrospective analysis of 22 cases.
    The Journal of small animal practice, 1998, Volume: 39, Issue:6

    Topics: Animals; Dog Diseases; Dogs; Male; Prazosin; Retrospective Studies; Sympatholytics; Treatment Outcom

1998
Postoperative urinary retention associated with total hip and total knee arthroplasties.
    Clinical orthopaedics and related research, 1991, Issue:269

    Topics: Aged; Anesthesia; Hip Prosthesis; Humans; Incidence; Knee Prosthesis; Male; Middle Aged; Postoperati

1991