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prazosin and Tachyarrhythmia

prazosin has been researched along with Tachyarrhythmia in 26 studies

Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.

Research Excerpts

ExcerptRelevanceReference
"Ventricular tachycardia developed after the abrupt withdrawal of clonidine in a patient with atrial septal defect of the ostium secundum type, renal insufficiency, and hypertension."7.67Ventricular tachycardia induced by clonidine withdrawal. ( Koiwaya, Y; Nakagawa, S; Yamamoto, Y, 1985)
"Prazosin was used as additional therapy in seven patients with severe chronic congestive cardiac failure."7.66Effect of prazosin on renal function in chronic congestive cardiac failure. ( Morgan, TO; Myers, JB; Walker, JN, 1981)
"Severe tachycardia, ventricular ectopy, and sodium retention manifested by hemodynamic deterioration developed with hydralazine hydrochloride therapy in chronic coronary heart disease with congestive failure refractory to digitalis, diuretics, and nitrates."7.66Hydralazine-induced tachycardia and sodium retention in heart failure. Hemodynamic and symptomatic correction by prazosin therapy. ( Amsterdam, EA; DeMaria, AN; Laslett, LJ; Mason, DT, 1978)
"We compared antihypertensive effects of monotherapy with pinacidil (N = 197) or prazosin (N = 204) in a randomized, parallel, double-blind dose-titration study in which hydrochlorothiazide or propranolol could be added for adverse events or lack of efficacy."6.66Vasodilator monotherapy in the treatment of hypertension: comparative efficacy and safety of pinacidil, a potassium channel opener, and prazosin. ( Goldberg, MR; Rockhold, FW; Sushak, CS; Thompson, WL, 1988)
"Ischemia-induced arrhythmias were studied during a 30 min period of occlusion of the left anterior descending (LAD) coronary artery, and 100% of control animals (n = 24) exhibited ventricular tachycardia and 63% ventricular fibrillation."5.27Ischemia- and reperfusion-induced arrhythmias in conscious rats--studies with prazosin and atenolol. ( Braimbridge, MV; Hearse, DJ; Kinoshita, K; Manning, AS, 1988)
" Prazosin injection produced hypotension and tachycardia in both groups (C=-43+/-3 mm Hg/98+/-16 bpm; SW=-61+/-5 mm Hg/115+/-32 bpm)."3.73Attenuated pressor responses to amino acids in the rostral ventrolateral medulla after swimming training in conscious rats. ( Basso, LS; Becker, LK; de Souza, HC; Garcia, MR; Lopes, OU; Martins-Pinge, MC; Neto, RV; Zoccal, DB, 2005)
" Atenolol neither modified HR nor BP variability in rats with hyperthyroidism."3.70Autonomic contribution to the blood pressure and heart rate variability changes in early experimental hyperthyroidism. ( Elghozi, JL; Laude, D; Ponchon, P; Safa-Tisseront, V, 1998)
"The combination of nifedipine and prazosin was more successful in preventing myocardial damage in 16 patients with hypertension than was nifedipine alone in two other patients with hypertension."3.68Management of the cardiovascular manifestations of poisoning by the Indian red scorpion (Mesobuthus tamulus). ( Bawaskar, HS; Bawaskar, PH, 1992)
"The antiarrhythmic and antifibrillatory actions of the alpha 1-adrenoceptor antagonist prazosin were evaluated in conscious dogs 4-7 days after anterior myocardial infarction."3.67Alpha-adrenergic influences in canine ischemic sudden death: effects of alpha 1-adrenoceptor blockade with prazosin. ( Lucchesi, BR; Lynch, JJ; Montgomery, DG; Wilber, DJ, 1987)
"Ventricular tachycardia developed after the abrupt withdrawal of clonidine in a patient with atrial septal defect of the ostium secundum type, renal insufficiency, and hypertension."3.67Ventricular tachycardia induced by clonidine withdrawal. ( Koiwaya, Y; Nakagawa, S; Yamamoto, Y, 1985)
"Prazosin was used as additional therapy in seven patients with severe chronic congestive cardiac failure."3.66Effect of prazosin on renal function in chronic congestive cardiac failure. ( Morgan, TO; Myers, JB; Walker, JN, 1981)
"Severe tachycardia, ventricular ectopy, and sodium retention manifested by hemodynamic deterioration developed with hydralazine hydrochloride therapy in chronic coronary heart disease with congestive failure refractory to digitalis, diuretics, and nitrates."3.66Hydralazine-induced tachycardia and sodium retention in heart failure. Hemodynamic and symptomatic correction by prazosin therapy. ( Amsterdam, EA; DeMaria, AN; Laslett, LJ; Mason, DT, 1978)
" Pharmacokinetic and pharmacodynamic modeling were performed subject by subject."2.73Pharmacokinetic and pharmacodynamic modelling of arterial haemodynamic effects of terazosin in healthy volunteers. ( Azanza, JR; Campanero, MA; Muñoz-Juarez, MJ; Quetglas, EG; Sádaba, B, 2008)
"We compared antihypertensive effects of monotherapy with pinacidil (N = 197) or prazosin (N = 204) in a randomized, parallel, double-blind dose-titration study in which hydrochlorothiazide or propranolol could be added for adverse events or lack of efficacy."2.66Vasodilator monotherapy in the treatment of hypertension: comparative efficacy and safety of pinacidil, a potassium channel opener, and prazosin. ( Goldberg, MR; Rockhold, FW; Sushak, CS; Thompson, WL, 1988)
"5."1.29omega-Conotoxin GVIA and prazosin, but not felodipine, cause postural hypotension in rabbits. ( Angus, JA; Hawkes, AL; Wright, CE, 1995)
"Ischemia-induced arrhythmias were studied during a 30 min period of occlusion of the left anterior descending (LAD) coronary artery, and 100% of control animals (n = 24) exhibited ventricular tachycardia and 63% ventricular fibrillation."1.27Ischemia- and reperfusion-induced arrhythmias in conscious rats--studies with prazosin and atenolol. ( Braimbridge, MV; Hearse, DJ; Kinoshita, K; Manning, AS, 1988)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199014 (53.85)18.7374
1990's9 (34.62)18.2507
2000's3 (11.54)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vayssettes-Courchay, C1
Bouysset, F1
Verbeuren, TJ1
Martins-Pinge, MC1
Becker, LK1
Garcia, MR1
Zoccal, DB1
Neto, RV1
Basso, LS1
de Souza, HC1
Lopes, OU1
Campanero, MA1
Sádaba, B1
Muñoz-Juarez, MJ1
Quetglas, EG1
Azanza, JR1
Uchida, W1
Kimura, T1
Satoh, S1
Benfey, BG1
Elfellah, MS1
Ogilvie, RI1
Varma, DR1
Ikram, H1
Espiner, EA1
Chan, W1
Nicholls, MG1
Myers, JB1
Morgan, TO1
Walker, JN1
Bawaskar, HS3
Bawaskar, PH3
Hawkes, AL1
Angus, JA1
Wright, CE1
Coruzzi, G1
Gambarelli, E1
Bertaccini, G1
Timmerman, H1
Chittacharoen, A1
Phuapradit, W1
Safa-Tisseront, V1
Ponchon, P1
Laude, D1
Elghozi, JL1
Rasmussen, K1
Laslett, LJ1
DeMaria, AN1
Amsterdam, EA1
Mason, DT1
Persson, PB1
Ehmke, H1
Kirchheim, HR1
Sundaram, K1
Murugaian, J1
Sapru, H1
Wilber, DJ1
Lynch, JJ1
Montgomery, DG1
Lucchesi, BR1
Jeffries, WB1
Tam, LT1
Wang, Y1
Smyth, DD1
Pettinger, WA1
Feldman, T1
Carroll, JD1
Munkenbeck, F1
Alibali, P1
Feldman, M1
Coggins, DL1
Gray, KR1
Bump, T1
Rochette, G1
Lecomte, J1
Kinoshita, K1
Hearse, DJ1
Braimbridge, MV1
Manning, AS1
Goldberg, MR1
Sushak, CS1
Rockhold, FW1
Thompson, WL1
Atkinson, J1
Luthi, P1
Sonnay, M1
Boillat, N1
Nakagawa, S1
Yamamoto, Y1
Koiwaya, Y1

Reviews

1 review available for prazosin and Tachyarrhythmia

ArticleYear
[Prazocin (Peripress, Pfizer)].
    Ugeskrift for laeger, 1977, May-23, Volume: 139, Issue:21

    Topics: Chemical Phenomena; Chemistry; Headache; Humans; Hypertension; Prazosin; Quinazolines; Tachycardia

1977

Trials

3 trials available for prazosin and Tachyarrhythmia

ArticleYear
Pharmacokinetic and pharmacodynamic modelling of arterial haemodynamic effects of terazosin in healthy volunteers.
    Clinical drug investigation, 2008, Volume: 28, Issue:3

    Topics: Abdominal Pain; Administration, Oral; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Anta

2008
Vasodilators: scorpion envenoming and the heart (an Indian experience).
    Toxicon : official journal of the International Society on Toxinology, 1994, Volume: 32, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Bradycardia; Cardiovascular Diseases; Child; Ch

1994
Vasodilator monotherapy in the treatment of hypertension: comparative efficacy and safety of pinacidil, a potassium channel opener, and prazosin.
    Clinical pharmacology and therapeutics, 1988, Volume: 44, Issue:1

    Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Data Interpretation, Statistical; Double-Blin

1988

Other Studies

22 other studies available for prazosin and Tachyarrhythmia

ArticleYear
Sympathetic activation and tachycardia in lipopolysaccharide treated rats are temporally correlated and unrelated to the baroreflex.
    Autonomic neuroscience : basic & clinical, 2005, Jun-15, Volume: 120, Issue:1-2

    Topics: Adrenergic alpha-Antagonists; Animals; Baroreflex; Blood Pressure; Denervation; Drug Interactions; E

2005
Attenuated pressor responses to amino acids in the rostral ventrolateral medulla after swimming training in conscious rats.
    Autonomic neuroscience : basic & clinical, 2005, Oct-30, Volume: 122, Issue:1-2

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiovascular System; Consciousness; Dose-Respons

2005
Presence of presynaptic inhibitory alpha 1-adrenoceptors in the cardiac sympathetic nerves of the dog: effects of prazosin and yohimbine on sympathetic neurotransmission to the heart.
    European journal of pharmacology, 1984, Aug-03, Volume: 103, Issue:1-2

    Topics: Animals; Clonidine; Dogs; Female; Heart Rate; Male; Methoxamine; Myocardium; Norepinephrine; Prazosi

1984
Anti-arrhythmic effects of prazosin and propranolol during coronary artery occlusion and re-perfusion in dogs and pigs.
    British journal of pharmacology, 1984, Volume: 82, Issue:3

    Topics: Animals; Arterial Occlusive Diseases; Blood Pressure; Coronary Disease; Dogs; Drug Therapy, Combinat

1984
A possible mechanism for "tachyphylaxis' to prazosin in heart failure.
    The New Zealand medical journal, 1980, Oct-22, Volume: 92, Issue:670

    Topics: Angiotensin II; Heart Diseases; Hemodynamics; Humans; Prazosin; Quinazolines; Renin; Tachycardia

1980
Effect of prazosin on renal function in chronic congestive cardiac failure.
    The Medical journal of Australia, 1981, Sep-19, Volume: 2, Issue:6

    Topics: Adult; Aged; Body Weight; Creatinine; Gout; Heart Failure; Humans; Kidney; Male; Middle Aged; Prazos

1981
omega-Conotoxin GVIA and prazosin, but not felodipine, cause postural hypotension in rabbits.
    Clinical and experimental pharmacology & physiology, 1995, Volume: 22, Issue:10

    Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Antihypertensive Agents; Blood Pressure

1995
Cardiovascular effects of the novel histamine H2 receptor agonist amthamine: interaction with the adrenergic system.
    Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 353, Issue:4

    Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cardiovascular System; Dimaprit; Dose-Respons

1996
Scorpion envenoming and the cardiovascular system.
    Tropical doctor, 1997, Volume: 27, Issue:1

    Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Animals; Antihypertensive Agents; Cardiovascular Di

1997
Pheochromocytoma during pregnancy: case report.
    The journal of obstetrics and gynaecology research, 1997, Volume: 23, Issue:2

    Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Female; Humans; Hypertension; Pheochromocytoma; Prazo

1997
Autonomic contribution to the blood pressure and heart rate variability changes in early experimental hyperthyroidism.
    Journal of hypertension, 1998, Volume: 16, Issue:12 Pt 2

    Topics: Animals; Atenolol; Atropine; Autonomic Nervous System; Blood Pressure; Cardiomegaly; Disease Models,

1998
Hydralazine-induced tachycardia and sodium retention in heart failure. Hemodynamic and symptomatic correction by prazosin therapy.
    Archives of internal medicine, 1978, Volume: 138, Issue:5

    Topics: Aged; Coronary Disease; Digitalis Glycosides; Female; Furosemide; Heart Failure; Humans; Hydralazine

1978
Management of the cardiovascular manifestations of poisoning by the Indian red scorpion (Mesobuthus tamulus).
    British heart journal, 1992, Volume: 68, Issue:5

    Topics: Adult; Aged; Animals; Cardiovascular Diseases; Child; Child, Preschool; Drug Therapy, Combination; F

1992
Blood pressure control in arterial- and cardiopulmonary receptor denervated dogs.
    Acta physiologica Scandinavica, 1991, Volume: 142, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arteries; Blood Pressure; Denervation; Dogs; Fema

1991
Microinjections of norepinephrine into the intermediolateral cell column of the spinal cord exert excitatory as well as inhibitory effects on the cardiac function.
    Brain research, 1991, Mar-29, Volume: 544, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Bradycardia; Dioxanes; Heart; Heart Rate; Idazoxan; Male; Mic

1991
Alpha-adrenergic influences in canine ischemic sudden death: effects of alpha 1-adrenoceptor blockade with prazosin.
    Journal of cardiovascular pharmacology, 1987, Volume: 10, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Arrhythmias, Cardiac; Dogs; Electrophysiology; Hemodynamics;

1987
Prazosin-induced alterations in renal alpha-adrenergic receptor function.
    Hypertension (Dallas, Tex. : 1979), 1987, Volume: 9, Issue:6 Pt 2

    Topics: Adrenergic beta-Agonists; Animals; Cocaine; Electric Stimulation; Hypotension; In Vitro Techniques;

1987
Hemodynamic recovery during simulated ventricular tachycardia: role of adrenergic receptor activation.
    American heart journal, 1988, Volume: 115, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Cardiac Pacing, Artificial; Dise

1988
[Several cardiovascular manifestations induced by vibrational stimuli].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1985, Volume: 179, Issue:4

    Topics: Adult; Autonomic Nervous System Diseases; Cardiovascular Diseases; Fingers; Humans; Hypertension; Me

1985
Ischemia- and reperfusion-induced arrhythmias in conscious rats--studies with prazosin and atenolol.
    Japanese circulation journal, 1988, Volume: 52, Issue:12

    Topics: Animals; Arrhythmias, Cardiac; Atenolol; Blood Pressure; Coronary Disease; Heart Rate; Male; Myocard

1988
Effect of acute administration of prazosin on blood pressure, heart rate and plasma renin level in the conscious normotensive rat.
    Clinical and experimental pharmacology & physiology, 1986, Volume: 13, Issue:7

    Topics: Animals; Blood Pressure; Female; Heart Rate; Injections, Subcutaneous; Prazosin; Propranolol; Rats;

1986
Ventricular tachycardia induced by clonidine withdrawal.
    British heart journal, 1985, Volume: 53, Issue:6

    Topics: Blood Pressure; Clonidine; Electrocardiography; Female; Humans; Middle Aged; Phentolamine; Prazosin;

1985