prazosin has been researched along with Shock, Septic in 7 studies
Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.
Shock, Septic: Sepsis associated with HYPOTENSION or hypoperfusion despite adequate fluid resuscitation. Perfusion abnormalities may include but are not limited to LACTIC ACIDOSIS; OLIGURIA; or acute alteration in mental status.
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, vasoconstriction due to clonidine post-ENDT even at maximal dosage (10(-3) M), was greatly attenuated in all four branching orders as in group II." | 1.29 | Attenuation of arteriolar alpha 2-adrenoceptor sensitivity during endotoxemia. ( Baker, CH; Nessellroth, S; Ortiz-Tweed, M; Price, JM; Sutton, ET, 1994) |
| " Individual dose-response curves (DRCs) for norepinephrine (NE) and histamine were performed to assess contractile function." | 1.28 | Regional differences in the effects of septic shock on vascular reactivity in the rabbit. ( Croce, K; Li, T; Winquist, RJ, 1992) |
| " A dose-response curve to NE, ANG II, and lysine vasopressin was also performed." | 1.27 | Angiotensin II, vasopressin, and sympathetic activity in conscious rats with endotoxemia. ( Brunner, HR; Nussberger, J; Schaller, MD; Waeber, B, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 5 (71.43) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baker, CH | 1 |
| Sutton, ET | 1 |
| Price, JM | 1 |
| Ortiz-Tweed, M | 1 |
| Nessellroth, S | 1 |
| Pittner, RA | 1 |
| Spitzer, JA | 1 |
| Maitra, SR | 1 |
| Sayeed, MM | 1 |
| Li, T | 1 |
| Croce, K | 1 |
| Winquist, RJ | 1 |
| Gonzalez, C | 1 |
| Fernandez, A | 1 |
| Martin, C | 1 |
| Moncada, S | 1 |
| Estrada, C | 1 |
| McMillan, M | 1 |
| Chernow, B | 1 |
| Roth, BL | 1 |
| Schaller, MD | 1 |
| Waeber, B | 1 |
| Nussberger, J | 1 |
| Brunner, HR | 1 |
7 other studies available for prazosin and Shock, Septic
| Article | Year |
|---|---|
Attenuation of arteriolar alpha 2-adrenoceptor sensitivity during endotoxemia.
Topics: Animals; Arterioles; Clonidine; Dioxanes; Endotoxins; Escherichia coli; Idazoxan; Male; Muscles; Phe | 1994 |
Shift from alpha- to beta-type adrenergic receptor-mediated responses in chronically endotoxemic rats.
Topics: Angiotensin II; Animals; Cells, Cultured; Chlorides; Endotoxins; Escherichia coli; Glucagon; Inosito | 1993 |
Effect of alpha-adrenergic blockage on cellular Ca2+ during endotoxic shock.
Topics: Animals; Calcium; Cells, Cultured; Endotoxins; Epinephrine; Liver; Male; Phentolamine; Prazosin; Rat | 1992 |
Regional differences in the effects of septic shock on vascular reactivity in the rabbit.
Topics: Animals; Drug Interactions; Female; Histamine; Male; Muscle, Smooth, Vascular; Nitroprusside; Norepi | 1992 |
Nitric oxide from endothelium and smooth muscle modulates responses to sympathetic nerve stimulation: implications for endotoxin shock.
Topics: Acetylcholine; Animals; Arginine; Cycloheximide; Dexamethasone; Dinoprost; Endothelium, Vascular; En | 1992 |
Hepatic alpha 1-adrenergic receptor alteration in a rat model of chronic sepsis.
Topics: Animals; Bacterial Infections; Chronic Disease; Dihydroergotoxine; Disease Models, Animal; Glucose; | 1986 |
Angiotensin II, vasopressin, and sympathetic activity in conscious rats with endotoxemia.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Captopril; Endotoxins; Epinephrine; M | 1985 |