prazosin has been researched along with Schizophrenia in 3 studies
Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.
Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.
| Excerpt | Relevance | Reference |
|---|---|---|
| "075 mg/kg trained animals clozapine at 3 mg/kg failed to shift the MK-801 dose-response curve to the right." | 1.30 | Does MK-801 discrimination constitute an animal model of schizophrenia useful for detecting atypical antipsychotics? ( Boyer-Millar, C; Goudie, AJ; Smith, JA, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stuchlík, A | 1 |
| Petrásek, T | 1 |
| Vales, K | 1 |
| Hommer, DW | 1 |
| Zahn, TP | 1 |
| Pickar, D | 1 |
| van Kammen, DP | 1 |
| Smith, JA | 1 |
| Boyer-Millar, C | 1 |
| Goudie, AJ | 1 |
1 trial available for prazosin and Schizophrenia
| Article | Year |
|---|---|
Prazosin, a specific alpha 1-noradrenergic receptor antagonist, has no effect on symptoms but increases autonomic arousal in schizophrenic patients.
Topics: Adolescent; Adrenergic alpha-Antagonists; Adrenergic Antagonists; Adult; Arousal; Autonomic Nervous | 1984 |
2 other studies available for prazosin and Schizophrenia
| Article | Year |
|---|---|
Effect of alpha(1)-adrenergic antagonist prazosin on behavioral alterations induced by MK-801 in a spatial memory task in Long-Evans rats.
Topics: Adrenergic alpha-Antagonists; Animals; Avoidance Learning; Disease Models, Animal; Dizocilpine Malea | 2009 |
Does MK-801 discrimination constitute an animal model of schizophrenia useful for detecting atypical antipsychotics?
Topics: Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Clozapine; Cues; Discrimination, Psycho | 1999 |