prazosin has been researched along with Reperfusion Injury in 10 studies
Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study, the effect of Prazosin, an α1-Adrenergic receptor antagonist, was investigated on the liver injury induced by kidney ischemia-reperfusion (I/R) in rats." | 8.31 | Prazosin Protects the Liver Against Renal Ischemia/Reperfusion Injury in Rats. ( Aghajani, S; Bagheri, Y; Bahraminia, F; Jafari, E; Kakaei, F; Khajepour, F; Mahmoodpoor, F; Vahed, SZ, 2023) |
| "Prazosin has shown protective effects against IR-injuries." | 5.72 | Prazosin Treatment Protects Brain and Heart by Diminishing Oxidative Stress and Apoptotic Pathways After Renal Ischemia Reperfusion. ( Aghajani, S; Ahmadian, E; Bagheri, Y; Jeddi, M; Malekinejad, Z; Qahremani, R; Shahbazi, S, 2022) |
| "Prazosin was administered by intraperitoneal injection 30 min prior to IR induction." | 5.62 | Renoprotective effects of prazosin on ischemia-reperfusion injury in rats. ( Bagheri, A; Bagheri, S; Bagheri, Y; Fathi, E; Jafari, S; Montazersaheb, S; Nia, AV; Rahimi, MM, 2021) |
| " In this study, the effect of Prazosin, an α1-Adrenergic receptor antagonist, was investigated on the liver injury induced by kidney ischemia-reperfusion (I/R) in rats." | 4.31 | Prazosin Protects the Liver Against Renal Ischemia/Reperfusion Injury in Rats. ( Aghajani, S; Bagheri, Y; Bahraminia, F; Jafari, E; Kakaei, F; Khajepour, F; Mahmoodpoor, F; Vahed, SZ, 2023) |
| " In those hearts exhibiting arrhythmias, [3H]-prazosin binding to alpha 1-adrenoceptors of ventricular membrane fractions was measured and compared with normally perfused time-matched controls." | 3.68 | Arrhythmias and alpha 1-adrenoceptor binding characteristics of the guinea-pig perfused heart during ischaemia and reperfusion. ( Broadley, KJ; Chess-Williams, RG; Sheridan, DJ, 1990) |
| "Prazosin has shown protective effects against IR-injuries." | 1.72 | Prazosin Treatment Protects Brain and Heart by Diminishing Oxidative Stress and Apoptotic Pathways After Renal Ischemia Reperfusion. ( Aghajani, S; Ahmadian, E; Bagheri, Y; Jeddi, M; Malekinejad, Z; Qahremani, R; Shahbazi, S, 2022) |
| "Prazosin was administered by intraperitoneal injection 30 min prior to IR induction." | 1.62 | Renoprotective effects of prazosin on ischemia-reperfusion injury in rats. ( Bagheri, A; Bagheri, S; Bagheri, Y; Fathi, E; Jafari, S; Montazersaheb, S; Nia, AV; Rahimi, MM, 2021) |
| "Prazosin or yohimbine treatment did not significantly influence the NE+hypoxia effect." | 1.42 | Noradrenaline enhances angiotensin II responses via p38 MAPK activation after hypoxia/re-oxygenation in renal interlobar arteries. ( Fähling, M; Gaestel, M; Hultström, M; Kaufmann, J; Liu, ZZ; Martinka, P; Moede, O; Moraes-Silva, IC; Nikitina, T; Patzak, A; Sendeski, M; Steege, A; Zavaritskaya, O, 2015) |
| "Ischemic acute renal failure was induced by occlusion of the left renal artery and vein for 45 min followed by reperfusion, 2 weeks after contralateral nephrectomy." | 1.34 | Selective antagonism of the postsynaptic alpha(1)-adrenoceptor is protective against ischemic acute renal failure in rats. ( Fujii, T; Kobuchi, S; Matsumura, Y; Ohkita, M; Sugiura, T; Takaoka, M, 2007) |
| "Reserpine pretreatment attenuated this protective effect of preconditioning on reperfusion-induced arrhythmias." | 1.30 | The possible role of adrenergic component in ischemic preconditioning. ( Sharma, A; Singh, M, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 3 (30.00) | 2.80 |
| Authors | Studies |
|---|---|
| Malekinejad, Z | 1 |
| Aghajani, S | 2 |
| Jeddi, M | 1 |
| Qahremani, R | 1 |
| Shahbazi, S | 1 |
| Bagheri, Y | 3 |
| Ahmadian, E | 1 |
| Khajepour, F | 1 |
| Mahmoodpoor, F | 1 |
| Jafari, E | 1 |
| Kakaei, F | 1 |
| Bahraminia, F | 1 |
| Vahed, SZ | 1 |
| Rahimi, MM | 1 |
| Bagheri, A | 1 |
| Fathi, E | 1 |
| Bagheri, S | 1 |
| Nia, AV | 1 |
| Jafari, S | 1 |
| Montazersaheb, S | 1 |
| Gao, L | 1 |
| Chen, L | 1 |
| Lu, ZZ | 1 |
| Gao, H | 1 |
| Wu, L | 1 |
| Chen, YX | 1 |
| Zhang, CM | 1 |
| Jiang, YK | 1 |
| Jing, Q | 1 |
| Zhang, YY | 1 |
| Yang, HT | 1 |
| Kaufmann, J | 1 |
| Martinka, P | 1 |
| Moede, O | 1 |
| Sendeski, M | 1 |
| Steege, A | 1 |
| Fähling, M | 1 |
| Hultström, M | 1 |
| Gaestel, M | 1 |
| Moraes-Silva, IC | 1 |
| Nikitina, T | 1 |
| Liu, ZZ | 1 |
| Zavaritskaya, O | 1 |
| Patzak, A | 1 |
| Fujii, T | 1 |
| Sugiura, T | 1 |
| Ohkita, M | 1 |
| Kobuchi, S | 1 |
| Takaoka, M | 1 |
| Matsumura, Y | 1 |
| Sharma, A | 1 |
| Singh, M | 1 |
| Joyeux, M | 1 |
| Godin-Ribuot, D | 1 |
| Patel, A | 1 |
| Demenge, P | 1 |
| Yellon, DM | 1 |
| Ribuot, C | 1 |
| Horio, T | 1 |
| Ito, S | 1 |
| Aoyama, M | 1 |
| Takeda, Y | 1 |
| Suzumura, H | 1 |
| Nakata, K | 1 |
| Yamada, Y | 1 |
| Suzuki, S | 1 |
| Fukutomi, T | 1 |
| Itoh, M | 1 |
| Chess-Williams, RG | 1 |
| Sheridan, DJ | 1 |
| Broadley, KJ | 1 |
10 other studies available for prazosin and Reperfusion Injury
| Article | Year |
|---|---|
Prazosin Treatment Protects Brain and Heart by Diminishing Oxidative Stress and Apoptotic Pathways After Renal Ischemia Reperfusion.
Topics: Acute Kidney Injury; Animals; Antioxidants; Apoptosis; Brain; Ischemia; Kidney; Oxidative Stress; Pr | 2022 |
Prazosin Protects the Liver Against Renal Ischemia/Reperfusion Injury in Rats.
Topics: Acute Kidney Injury; Animals; Ischemia; Kidney; Liver; Male; Oxidative Stress; Prazosin; Rats; Rats, | 2023 |
Renoprotective effects of prazosin on ischemia-reperfusion injury in rats.
Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Apoptosis; Cytokines; Kidney; Male; NF-kappa | 2021 |
Activation of α1B-adrenoceptors contributes to intermittent hypobaric hypoxia-improved postischemic myocardial performance via inhibiting MMP-2 activation.
Topics: Actinin; Adrenergic alpha-1 Receptor Antagonists; Animals; Doxycycline; Hypoxia; Male; Matrix Metall | 2014 |
Noradrenaline enhances angiotensin II responses via p38 MAPK activation after hypoxia/re-oxygenation in renal interlobar arteries.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic beta-An | 2015 |
Selective antagonism of the postsynaptic alpha(1)-adrenoceptor is protective against ischemic acute renal failure in rats.
Topics: Acute Kidney Injury; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; | 2007 |
The possible role of adrenergic component in ischemic preconditioning.
Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Blood Pressure; Catecholamines; | 1997 |
Infarct size-reducing effect of heat stress and alpha1 adrenoceptors in rats.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Heat Stress Disorders; Heat-Shock Proteins; HSP72 | 1998 |
Effect of carvedilol on atrioventricular conduction in the ischemic heart.
Topics: Action Potentials; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Bundle of His | 2001 |
Arrhythmias and alpha 1-adrenoceptor binding characteristics of the guinea-pig perfused heart during ischaemia and reperfusion.
Topics: Adrenergic Agonists; Adrenergic alpha-Antagonists; Animals; Arrhythmias, Cardiac; Guinea Pigs; Heart | 1990 |