Page last updated: 2024-11-03

prazosin and Pyrexia

prazosin has been researched along with Pyrexia in 19 studies

Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.

Research Excerpts

ExcerptRelevanceReference
" The thermoregulatory, effector processes were investigated after treatment with prazosin (PRA), dihydrobenzperidol (DHBP) and nifedipin (ADA) applied to the thermosensitive zone of the anterior hypothalamus (PO/AH) on normothermic and feverish rabbits (LPS, lipopolysaccharide E."7.68Inhibition of pyrogen Escherichia coli fever with intracerebral administration of prazosin, dihydrobenzperidol and nifedipin in the rabbits. ( Korolkiewicz, Z; Szreder, Z, 1991)
" The thermoregulatory, effector processes were investigated after treatment with prazosin (PRA), dihydrobenzperidol (DHBP) and nifedipin (ADA) applied to the thermosensitive zone of the anterior hypothalamus (PO/AH) on normothermic and feverish rabbits (LPS, lipopolysaccharide E."3.68Inhibition of pyrogen Escherichia coli fever with intracerebral administration of prazosin, dihydrobenzperidol and nifedipin in the rabbits. ( Korolkiewicz, Z; Szreder, Z, 1991)
" Yohimbine, in small doses, but not prazosin and propranolol, when injected into the cerebral ventricles, attenuated the hypothermia evoked by i."3.67Nature of hypo- and hyperthermia induced by the calcium antagonist nicardipine. ( Beleslin, DB; Jovanović-Micić, D; Samardzić, R, 1987)
"Melatonin is a neurohormone that has anticonvulsant activity in different experimental seizure models including hyperthermic febrile seizure."1.51Role of Melatonin Receptors in Hyperthermia-Induced Acute Seizure Model of Rats. ( Aydin, L; Baltaci, AK; Mogulkoc, R, 2019)
"Treatment with prazosin (1mg/kg, i."1.36Role of serotonin and/or norepinephrine in the MDMA-induced increase in extracellular glucose and glycogenolysis in the rat brain. ( Bhide, N; Gudelsky, GA; Pachmerhiwala, R; Straiko, M, 2010)
"Prazosin pretreatment eliminated the first T(c) rise but not the second; PGE(2) rose normally."1.34Preoptic norepinephrine mediates the febrile response of guinea pigs to lipopolysaccharide. ( Blatteis, CM; Feleder, C; Perlik, V, 2007)
"Nantenine functions as an effective antagonist against a wide range of MDMA-induced effects in mice."1.32Nantenine: an antagonist of the behavioral and physiological effects of MDMA in mice. ( Chen, X; Fantegrossi, WE; Karabenick, RL; Kiessel, CL; Leach, PT; Ohizumi, Y; Rice, KC; Ullrich, T; Van Martin, C; Woods, JH, 2004)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19902 (10.53)18.7374
1990's6 (31.58)18.2507
2000's7 (36.84)29.6817
2010's4 (21.05)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mogulkoc, R1
Baltaci, AK1
Aydin, L1
Docherty, JR2
Bexis, S2
Alawi, KM1
Aubdool, AA1
Liang, L1
Wilde, E1
Vepa, A1
Psefteli, MP1
Brain, SD1
Keeble, JE1
Chua, YA1
Nurhaslina, H1
Gan, SH1
Pachmerhiwala, R1
Bhide, N1
Straiko, M1
Gudelsky, GA1
Sprague, JE2
Banks, ML1
Cook, VJ1
Mills, EM2
Fantegrossi, WE1
Kiessel, CL1
Leach, PT1
Van Martin, C1
Karabenick, RL1
Chen, X1
Ohizumi, Y1
Ullrich, T1
Rice, KC1
Woods, JH1
Brutcher, RE1
Caden, D1
Rusyniak, DE1
Feleder, C2
Perlik, V2
Blatteis, CM2
Nonogaki, K1
Iguchi, A1
Sakamoto, N1
Bencsics, A1
Elenkov, IJ1
Vizi, ES1
Gagało, I1
Szreder, Z3
Fyda, DM1
Cooper, KE1
Veale, WL1
Korolkiewicz, Z1
Beleslin, DB1
Jovanović-Micić, D1
Samardzić, R1
Junnarkar, AY1
Singh, PP1

Other Studies

19 other studies available for prazosin and Pyrexia

ArticleYear
Role of Melatonin Receptors in Hyperthermia-Induced Acute Seizure Model of Rats.
    Journal of molecular neuroscience : MN, 2019, Volume: 69, Issue:4

    Topics: Animals; Anticonvulsants; Brain; Central Nervous System Depressants; Fever; Male; Melatonin; Prazosi

2019
Influence of ketanserin on the effects of methylenedioxymethamphetamine on body temperature in the mouse.
    Autonomic & autacoid pharmacology, 2013, Volume: 33, Issue:3-4

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic Uptake Inhibitors; Animals; Aorta; Body Temperat

2013
The sympathetic nervous system is controlled by transient receptor potential vanilloid 1 in the regulation of body temperature.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2015, Volume: 29, Issue:10

    Topics: Acrylamides; Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Body Tem

2015
Hyperthermic effects of Durio zibethinus and its interaction with paracetamol.
    Methods and findings in experimental and clinical pharmacology, 2008, Volume: 30, Issue:10

    Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Asia, Southeastern; Blood Pr

2008
Role of serotonin and/or norepinephrine in the MDMA-induced increase in extracellular glucose and glycogenolysis in the rat brain.
    European journal of pharmacology, 2010, Oct-10, Volume: 644, Issue:1-3

    Topics: Animals; Brain; Fever; Fluoxetine; Glucose; Glycogenolysis; Male; N-Methyl-3,4-methylenedioxyampheta

2010
Hypothalamic-pituitary-thyroid axis and sympathetic nervous system involvement in hyperthermia induced by 3,4-methylenedioxymethamphetamine (Ecstasy).
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 305, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Adrenergic alpha-Antagonists; Animals; Drug Interactions; Fever; Hypo

2003
Nantenine: an antagonist of the behavioral and physiological effects of MDMA in mice.
    Psychopharmacology, 2004, Volume: 173, Issue:3-4

    Topics: Adrenergic alpha-Antagonists; Animals; Aporphines; Behavior, Animal; Crowding; Dose-Response Relatio

2004
Attenuation of 3,4-methylenedioxymethamphetamine (MDMA, Ecstasy)-induced rhabdomyolysis with alpha1- plus beta3-adrenoreceptor antagonists.
    British journal of pharmacology, 2004, Volume: 142, Issue:4

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-3 Receptor Antagonists; Animals; Blood Urea

2004
Preoptic nitric oxide attenuates endotoxic fever in guinea pigs by inhibiting the POA release of norepinephrine.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2007, Volume: 293, Issue:3

    Topics: Acetaminophen; Adrenergic alpha-Antagonists; Animals; Body Temperature; Catheterization; Cyclooxygen

2007
Preoptic norepinephrine mediates the febrile response of guinea pigs to lipopolysaccharide.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2007, Volume: 293, Issue:3

    Topics: Acetaminophen; Adrenergic alpha-Antagonists; Animals; Body Temperature; Catheterization; Cyclooxygen

2007
Role of alpha1-adrenoceptor subtypes in the effects of methylenedioxy methamphetamine (MDMA) on body temperature in the mouse.
    British journal of pharmacology, 2008, Volume: 153, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Body Temperature; Fever; Male;

2008
Effects of adrenoceptor antagonists on the hyperthermia and hyperglycemia induced by prostaglandin F2 alpha in rats.
    European journal of pharmacology, 1994, Sep-01, Volume: 262, Issue:1-2

    Topics: Adrenergic alpha-Antagonists; Animals; Blood Glucose; Body Temperature; Dinoprost; Fever; Hyperglyce

1994
alpha 2-, alpha 2A-, alpha 2B/2C-Adrenoceptor subtype antagonists prevent lipopolysaccharide-induced fever response in rabbits.
    Brain research, 1995, Dec-24, Volume: 705, Issue:1-2

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-A

1995
The effect of doxazosin, urapidil and indoramin pretreatment on fever produced by E. coli lipopolysaccharide in rabbits.
    General pharmacology, 1991, Volume: 22, Issue:5

    Topics: Adrenergic alpha-Antagonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature Reg

1991
Contribution of brown adipose tissue to central PGE1-evoked hyperthermia in rats.
    The American journal of physiology, 1991, Volume: 260, Issue:1 Pt 2

    Topics: Adipose Tissue; Adipose Tissue, Brown; Alprostadil; Animals; Blood Pressure; Cardiovascular Physiolo

1991
Inhibition of pyrogen Escherichia coli fever with intracerebral administration of prazosin, dihydrobenzperidol and nifedipin in the rabbits.
    General pharmacology, 1991, Volume: 22, Issue:2

    Topics: Animals; Body Temperature Regulation; Droperidol; Escherichia coli; Female; Fever; Hypothalamus, Ant

1991
Comparison of the effect of prazosin with that of dihydrobenzperidol and nifidepine on thermoregulatory responses produced by pyrogen in rabbits.
    General pharmacology, 1990, Volume: 21, Issue:6

    Topics: Animals; Body Temperature Regulation; Droperidol; Female; Fever; Infusions, Intravenous; Injections,

1990
Nature of hypo- and hyperthermia induced by the calcium antagonist nicardipine.
    Archives internationales de physiologie et de biochimie, 1987, Volume: 95, Issue:4

    Topics: Animals; Body Temperature Regulation; Cats; Fever; Hypothermia; Injections, Intraventricular; Ion Ch

1987
Antagonism of clonidine-induced hypothermia by alpha adrenoceptor antagonists in electrically stimulated mice.
    Pharmacological research communications, 1988, Volume: 20, Issue:6

    Topics: Adrenergic alpha-Antagonists; Animals; Body Temperature; Clonidine; Electroshock; Fever; Male; Mice;

1988