prazosin has been researched along with Ptosis, Eyelid in 5 studies
Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment with prazosin, a nonselective α1-adrenoceptor antagonist, completely abolished the above METH-induced responses." | 1.39 | Alpha(1A)-adrenergic control of piloerection and palpebral fissure width in rats. ( Ishizaka, M; Kikuchi-Utsumi, K; Matsumura, N; Nakaki, T, 2013) |
| "Severe vomiting was evoked by Apo in dogs, but not by Eph even when lethal dose (20 mg." | 1.28 | [Comparison of central stimulating effects between ephedrine and apomorphine]. ( Li, BH; Li, Q, 1991) |
| " Under these conditions the LD50 was 277 mg/kg for males and 293 mg/kg for females." | 1.27 | Terazosin: intravenous safety evaluation in rats. ( Cusick, PK; Fort, FL; Heyman, IA; Kesterson, JW; Majors, K; Tekeli, S, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kikuchi-Utsumi, K | 1 |
| Ishizaka, M | 1 |
| Matsumura, N | 1 |
| Nakaki, T | 1 |
| Fort, FL | 1 |
| Tekeli, S | 1 |
| Majors, K | 1 |
| Heyman, IA | 1 |
| Cusick, PK | 1 |
| Kesterson, JW | 1 |
| Li, Q | 1 |
| Li, BH | 1 |
| Poncelet, M | 1 |
| Brochet, D | 1 |
| Chermat, R | 1 |
| Simon, P | 1 |
| Maj, J | 1 |
| Michaluk, J | 1 |
| Rawłów, A | 1 |
| Rogóz, Z | 1 |
| Skuza, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Treatment With Tamsulosin for Upper Eyelid Retraction Related to Thyroid Eye Disease.[NCT04359979] | 50 participants (Anticipated) | Interventional | 2020-05-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 other studies available for prazosin and Ptosis, Eyelid
| Article | Year |
|---|---|
Alpha(1A)-adrenergic control of piloerection and palpebral fissure width in rats.
Topics: Adrenergic Agents; Animals; Blepharoptosis; Indoles; Male; Methamphetamine; Piloerection; Prazosin; | 2013 |
Terazosin: intravenous safety evaluation in rats.
Topics: Animals; Antihypertensive Agents; Blepharoptosis; Body Temperature; Body Weight; Dose-Response Relat | 1984 |
[Comparison of central stimulating effects between ephedrine and apomorphine].
Topics: Animals; Apomorphine; Blepharoptosis; Catalepsy; Ephedrine; Haloperidol; Male; Mice; Motor Activity; | 1991 |
Antidepressant-like effects of diphenylhydantoin in mice: involvement of alpha-adrenoceptors.
Topics: Animals; Antidepressive Agents; Blepharoptosis; Helplessness, Learned; In Vitro Techniques; Male; Mi | 1986 |
Central action of the antidepressant drug pirlindole.
Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Blepharoptosis; Body Temperature; Carbazoles; C | 1986 |