Page last updated: 2024-11-03

prazosin and Neuralgia

prazosin has been researched along with Neuralgia in 4 studies

Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.

Neuralgia: Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.

Research Excerpts

ExcerptRelevanceReference
"Established allodynia (by day 21) was partly reversed by the re-uptake inhibitor reboxetine (5 μg, i."1.39Endogenous analgesic action of the pontospinal noradrenergic system spatially restricts and temporally delays the progression of neuropathic pain following tibial nerve injury. ( Hickey, L; Hughes, SW; Hulse, RP; Lumb, BM; Pickering, AE, 2013)
"Neuropathic pain is a serious chronic disorder caused by lesion or dysfunction in the nervous systems."1.36Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de ( Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K, 2010)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hayashi, S1
Nakata, E1
Morita, A1
Mizuno, K1
Yamamura, K1
Kato, A1
Ohashi, K1
Hughes, SW1
Hickey, L1
Hulse, RP1
Lumb, BM1
Pickering, AE1
Wei, H1
Jin, CY1
Viisanen, H1
You, HJ1
Pertovaara, A1
Ogon, I1
Takebayashi, T1
Miyakawa, T1
Iwase, T1
Tanimoto, K1
Terashima, Y1
Jimbo, S1
Kobayashi, T1
Tohse, N1
Yamashita, T1

Other Studies

4 other studies available for prazosin and Neuralgia

ArticleYear
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
    Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21

    Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes,

2010
Endogenous analgesic action of the pontospinal noradrenergic system spatially restricts and temporally delays the progression of neuropathic pain following tibial nerve injury.
    Pain, 2013, Volume: 154, Issue:9

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Analysis of Varian

2013
Histamine in the locus coeruleus promotes descending noradrenergic inhibition of neuropathic hypersensitivity.
    Pharmacological research, 2014, Volume: 90

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic Neurons; A

2014
Attenuation of pain behaviour by local administration of alpha-2 adrenoceptor antagonists to dorsal root ganglia in a rat radiculopathy model.
    European journal of pain (London, England), 2016, Volume: 20, Issue:5

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-A

2016