prazosin has been researched along with Multiple System Atrophy in 2 studies
Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.
Multiple System Atrophy: A syndrome complex composed of three conditions which represent clinical variants of the same disease process: STRIATONIGRAL DEGENERATION; SHY-DRAGER SYNDROME; and the sporadic form of OLIVOPONTOCEREBELLAR ATROPHIES. Clinical features include autonomic, cerebellar, and basal ganglia dysfunction. Pathologic examination reveals atrophy of the basal ganglia, cerebellum, pons, and medulla, with prominent loss of autonomic neurons in the brain stem and spinal cord. (From Adams et al., Principles of Neurology, 6th ed, p1076; Baillieres Clin Neurol 1997 Apr;6(1):187-204; Med Clin North Am 1999 Mar;83(2):381-92)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Papay, R | 1 |
| Zuscik, MJ | 1 |
| Ross, SA | 1 |
| Yun, J | 1 |
| McCune, DF | 1 |
| Gonzalez-Cabrera, P | 1 |
| Gaivin, R | 1 |
| Drazba, J | 1 |
| Perez, DM | 1 |
| Sakakibara, R | 1 |
| Hattori, T | 1 |
| Uchiyama, T | 1 |
| Suenaga, T | 1 |
| Takahashi, H | 1 |
| Yamanishi, T | 1 |
| Egoshi, K | 1 |
| Sekita, N | 1 |
1 trial available for prazosin and Multiple System Atrophy
| Article | Year |
|---|---|
Are alpha-blockers involved in lower urinary tract dysfunction in multiple system atrophy? A comparison of prazosin and moxisylyte.
Topics: Adrenergic alpha-Antagonists; Aged; Female; Humans; Male; Middle Aged; Moxisylyte; Multiple System A | 2000 |
1 other study available for prazosin and Multiple System Atrophy
| Article | Year |
|---|---|
Mice expressing the alpha(1B)-adrenergic receptor induces a synucleinopathy with excessive tyrosine nitration but decreased phosphorylation.
Topics: Adrenergic alpha-Antagonists; alpha-Synuclein; Animals; Body Weight; Brain; Cerebellum; Disease Mode | 2002 |