Page last updated: 2024-11-03

prazosin and Morphine Abuse

prazosin has been researched along with Morphine Abuse in 8 studies

Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.

Research Excerpts

ExcerptRelevanceReference
"Pretreatment with yohimbine (alpha(2)-adrenoceptor) or prazosin (alpha(1)-adrenoceptor) 15 min prior to naloxone administration attenuated some of the behavioural signs of morphine withdrawal."5.31Changes in catecholaminergic pathways innervating the rat heart ventricle during morphine dependence. Involvement Of alpha(1)- and alpha(2)-adrenoceptors. ( Laorden, ML; Milanés, MV, 2000)
"Pretreatment with yohimbine (alpha(2)-adrenoceptor) or prazosin (alpha(1)-adrenoceptor) 15 min prior to naloxone administration attenuated some of the behavioural signs of morphine withdrawal."1.31Changes in catecholaminergic pathways innervating the rat heart ventricle during morphine dependence. Involvement Of alpha(1)- and alpha(2)-adrenoceptors. ( Laorden, ML; Milanés, MV, 2000)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's1 (12.50)18.2507
2000's6 (75.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zarrindast, MR2
Assadi, E1
Oryan, S1
Torkaman-Boutorabi, A2
Sahebgharani, M1
Dang, VC1
Williams, JT1
Laorden, ML2
Fuertes, G1
González-Cuello, A1
Milanés, MV2
Cruz, SL1
Rodríguez-Manzo, G1
van der Laan, JW1
Jansen van't Land, C1
Berthold, H1
Fozard, JR1
Engel, G1

Other Studies

8 other studies available for prazosin and Morphine Abuse

ArticleYear
Influence of histamine, cimetidine and pyrilamine on naloxone-induced jumping in morphine-dependent mice.
    European journal of pharmacology, 2003, Jun-20, Volume: 471, Issue:2

    Topics: Animals; Atropine; Cimetidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug

2003
Effects of imipramine on the expression and development of morphine dependence in mice.
    European journal of pharmacology, 2003, Jul-18, Volume: 473, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Clon

2003
Chronic morphine treatment reduces recovery from opioid desensitization.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Sep-01, Volume: 24, Issue:35

    Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Cocaine; Drug Tolerance; Enkephalin, Methi

2004
Changes in catecholaminergic pathways innervating paraventricular nucleus and pituitary-adrenal axis response during morphine dependence: implication of alpha(1)- and alpha(2)-adrenoceptors.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 293, Issue:2

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-A

2000
Gender differences in the cardiovascular responses to morphine and naloxone in spinal rats.
    European journal of pharmacology, 2000, May-26, Volume: 397, Issue:1

    Topics: Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Blood Pressure; Cardiovascular System; Do

2000
Changes in catecholaminergic pathways innervating the rat heart ventricle during morphine dependence. Involvement Of alpha(1)- and alpha(2)-adrenoceptors.
    European journal of pharmacology, 2000, Jun-02, Volume: 397, Issue:2-3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Catechola

2000
Chronic infusion of clonidine does not alleviate spontaneous morphine withdrawal symptoms in rats.
    Psychopharmacology, 1992, Volume: 108, Issue:3

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; D

1992
5-HT1 receptor agonists attenuate the naloxone-induced jumping behaviour in morphine-dependent mice.
    European journal of pharmacology, 1989, Mar-14, Volume: 162, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Ani

1989