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prazosin and Mitral Incompetence

prazosin has been researched along with Mitral Incompetence in 17 studies

Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.

Research Excerpts

ExcerptRelevanceReference
"Therapy with prazosin can improve the condition of patients with congestive heart failure due to its vasodilating action."3.66Noninvasive assessment of left ventricular wall stress in chronic congestive heart failure patients. ( Abdou, O; Chandy, F; Gopalaswamy, C; Gould, L, 1983)
"Four dogs with congestive heart failure associated with dirofilariasis and mitral valvular incompetence initially responded to treatment with digoxin or etamiphylline camsylate, and frusemide but became refractory to this therapy and were in cardiac decompensation."3.66The use of alpha blockade in the treatment of congestive heart failure associated with dirofilariasis and mitral valvular incompetence. ( Atwell, RB, 1979)
"Prazosin treatment prevented the deterioration of the left ventricular contractility and function and also prevented the increase in the sarcolemmal Na+-K+-ATPase observed in failing heart."1.27Effect of prazosin treatment on the cardiac sarcolemmal ATPase in failing heart due to mitral insufficiency in dogs. ( Bharadwaj, B; O'Neil, CL; Prasad, K, 1985)
"Prazosin treatment produced an improvement in the hemodynamics which was associated with a decreased in the extracellular space, and intracellular K+, and an increase in the intracellular Ca++."1.27Effect of chronic prazosin treatment on the cardiac function and electrolytes in failing heart due to chronic mitral insufficiency. ( Bharadwaj, B; O'Neil, CL; Prasad, K, 1985)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199015 (88.24)18.7374
1990's1 (5.88)18.2507
2000's1 (5.88)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kamblock, J1
N'Guyen, L1
Pagis, B1
Costes, P1
Le Goanvic, C1
Lionet, P1
Maheu, B1
Papouin, G1
Beekman, RH1
Rocchini, AP1
Dick, M1
Crowley, DC1
Rosenthal, A1
Rumiński, W1
Markiewicz, M1
Przegaliński, J1
Sterz, H1
Cohn, JN1
Juillard, A1
Batalla, N1
Leroy, G1
Fernandez, F1
Gerbaux, A1
Wagner, GC1
Robinson, PH1
Gould, L1
Gopalaswamy, C1
Chandy, F1
Abdou, O1
Chatterjee, K1
Rouleau, JL1
Massie, BM1
Conti, CR2
Miles, D1
Mehta, J2
Feldman, RL1
Nichols, WW1
Pepine, CJ1
Uehara, Y1
Takahashi, M1
Atwell, RB1
Prasad, K2
O'Neil, CL2
Bharadwaj, B2
Lavítola, Pde L1
de Moraes, AV1
Dallan, L1
Grinberg, M1
Sosa, EA1
Higa, SS1
Bessegato, L1
Pileggi, F1
Kozáková, M1
Poch, T1

Reviews

1 review available for prazosin and Mitral Incompetence

ArticleYear
Vasodilator therapy of congestive heart failure.
    Advances in internal medicine, 1980, Volume: 26

    Topics: Aortic Valve Insufficiency; Captopril; Dobutamine; Heart Failure; Humans; Hydralazine; Isosorbide Di

1980

Trials

1 trial available for prazosin and Mitral Incompetence

ArticleYear
[Comparative study of vasodilator drugs in heart valve diseases].
    Arquivos brasileiros de cardiologia, 1987, Volume: 48, Issue:3

    Topics: Adolescent; Adult; Aortic Valve Insufficiency; Clinical Trials as Topic; Echocardiography; Female; H

1987

Other Studies

15 other studies available for prazosin and Mitral Incompetence

ArticleYear
Acute severe mitral regurgitation during first attacks of rheumatic fever: clinical spectrum, mechanisms and prognostic factors.
    The Journal of heart valve disease, 2005, Volume: 14, Issue:4

    Topics: Acute Disease; Adrenal Cortex Hormones; Adrenergic alpha-Antagonists; Angiotensin-Converting Enzyme

2005
Vasodilator therapy in children: acute and chronic effects in children with left ventricular dysfunction or mitral regurgitation.
    Pediatrics, 1984, Volume: 73, Issue:1

    Topics: Adolescent; Captopril; Cardiac Catheterization; Child; Child, Preschool; Digoxin; Heart Failure; Hea

1984
[Hemodynamic effect of prazosin in patients with aortic and mitral valve insufficiency].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1983, Sep-26, Volume: 38, Issue:39

    Topics: Adult; Aortic Valve Insufficiency; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; M

1983
[Causes of acute valve-conditioned left ventricular insufficiency-- attempt at a tabulated review].
    Wiener medizinische Wochenschrift (1946), 1984, Mar-15, Volume: 134, Issue:5

    Topics: Aortic Valve Insufficiency; Cardiac Glycosides; Dyspnea; Endocarditis, Bacterial; Humans; Hydralazin

1984
[Hemodynamic effects of a single dose of prazosin in 8 cases of mitral or aortic regurgitation].
    Archives des maladies du coeur et des vaisseaux, 1981, Volume: 74, Issue:10

    Topics: Adult; Aortic Valve Insufficiency; Female; Hemodynamics; Humans; Male; Mitral Valve Insufficiency; P

1981
The role of vasodilator therapy in the management of the patient with acute myocardial infarction.
    Primary care, 1981, Volume: 8, Issue:3

    Topics: Heart Failure; Heart Rupture; Hemodynamics; Humans; Hydralazine; Mitral Valve Insufficiency; Myocard

1981
Noninvasive assessment of left ventricular wall stress in chronic congestive heart failure patients.
    Angiology, 1983, Volume: 34, Issue:2

    Topics: Adult; Aged; Aortic Valve Insufficiency; Blood Pressure; Echocardiography; Female; Heart; Heart Fail

1983
Hydralazine in chronic CHF.
    Acta medica Scandinavica. Supplementum, 1981, Volume: 652

    Topics: Administration, Oral; Aortic Valve Insufficiency; Cardiac Output; Chronic Disease; Drug Therapy, Com

1981
[Usefulness of vasodilators in congestive cardiac insufficiency: studies with prazosin].
    Cardiology, 1980, Volume: 66 Suppl 2

    Topics: Adult; Aged; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Mitral Valve Insufficiency; Nit

1980
Acute haemodynamic effects of oral prazosin in severe mitral regurgitation.
    British heart journal, 1980, Volume: 43, Issue:5

    Topics: Adult; Aged; Blood Pressure; Cardiac Output; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Mi

1980
Hemodynamic changes during administration of drugs for mitral regurgitation in dogs.
    The Journal of veterinary medical science, 1998, Volume: 60, Issue:2

    Topics: Animals; Captopril; Cardiotonic Agents; Digoxin; Dog Diseases; Dogs; Echocardiography, Doppler, Colo

1998
The use of alpha blockade in the treatment of congestive heart failure associated with dirofilariasis and mitral valvular incompetence.
    The Veterinary record, 1979, Feb-10, Volume: 104, Issue:6

    Topics: Animals; Digoxin; Dirofilariasis; Dog Diseases; Dogs; Female; Furosemide; Heart Failure; Male; Mitra

1979
Effect of prazosin treatment on the cardiac sarcolemmal ATPase in failing heart due to mitral insufficiency in dogs.
    Cardiovascular research, 1985, Volume: 19, Issue:7

    Topics: Adenosine Triphosphatases; Animals; Ca(2+) Mg(2+)-ATPase; Dogs; Female; Hemodynamics; Male; Mitral V

1985
[The effect of vasodilator therapy on mitral and aortic insufficiency in a Doppler echocardiography study].
    Vnitrni lekarstvi, 1987, Volume: 33, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aortic Valve Insufficiency; Echocardiography; Female; Humans; Male;

1987
Effect of chronic prazosin treatment on the cardiac function and electrolytes in failing heart due to chronic mitral insufficiency.
    The Canadian journal of cardiology, 1985, Volume: 1, Issue:2

    Topics: Animals; Calcium; Dogs; Female; Heart Failure; Hemodynamics; Male; Mitral Valve Insufficiency; Myoca

1985