prazosin has been researched along with Liver Dysfunction in 4 studies
Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Prazosin prevented hepatotoxicity when administered 1 h before a toxic paracetamol insult and importantly, when administered up to 1 h post paracetamol injection." | 1.35 | alpha(1)-Adrenoceptor antagonists prevent paracetamol-induced hepatotoxicity in mice. ( Kitteringham, NR; Macdonald, I; Park, BK; Randle, LE; Sathish, JG; Williams, DP, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Oben, JA | 1 |
| Roskams, T | 1 |
| Yang, S | 1 |
| Lin, H | 1 |
| Sinelli, N | 1 |
| Li, Z | 1 |
| Torbenson, M | 1 |
| Huang, J | 1 |
| Guarino, P | 1 |
| Kafrouni, M | 1 |
| Diehl, AM | 1 |
| Clement, YN | 1 |
| Williams, AF | 1 |
| Randle, LE | 1 |
| Sathish, JG | 1 |
| Kitteringham, NR | 1 |
| Macdonald, I | 1 |
| Williams, DP | 1 |
| Park, BK | 1 |
| Lee, JC | 1 |
| Saunders, GK | 1 |
| Sponenberg, DP | 1 |
4 other studies available for prazosin and Liver Dysfunction
| Article | Year |
|---|---|
Sympathetic nervous system inhibition increases hepatic progenitors and reduces liver injury.
Topics: Adrenergic alpha-Antagonists; Animals; Antioxidants; Body Weight; Diet; Fatty Liver; Hepatocytes; Li | 2003 |
Protection against paracetamol-induced hepatic injury by prazosin pre-treatment in CD-1 mice.
Topics: Acetaminophen; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alanine Transaminase; Analge | 2005 |
alpha(1)-Adrenoceptor antagonists prevent paracetamol-induced hepatotoxicity in mice.
Topics: Acetaminophen; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Catec | 2008 |
Hepatic necrosis induced by norepinephrine in rabbits.
Topics: Alanine Transaminase; Animals; Calcium; Chemical and Drug Induced Liver Injury; Liver; Liver Disease | 1987 |