Page last updated: 2024-11-03

prazosin and Liver Diseases

prazosin has been researched along with Liver Diseases in 4 studies

Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.

Liver Diseases: Pathological processes of the LIVER.

Research Excerpts

ExcerptRelevanceReference
" Prazosin prevented hepatotoxicity when administered 1 h before a toxic paracetamol insult and importantly, when administered up to 1 h post paracetamol injection."1.35alpha(1)-Adrenoceptor antagonists prevent paracetamol-induced hepatotoxicity in mice. ( Kitteringham, NR; Macdonald, I; Park, BK; Randle, LE; Sathish, JG; Williams, DP, 2008)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Oben, JA1
Roskams, T1
Yang, S1
Lin, H1
Sinelli, N1
Li, Z1
Torbenson, M1
Huang, J1
Guarino, P1
Kafrouni, M1
Diehl, AM1
Clement, YN1
Williams, AF1
Randle, LE1
Sathish, JG1
Kitteringham, NR1
Macdonald, I1
Williams, DP1
Park, BK1
Lee, JC1
Saunders, GK1
Sponenberg, DP1

Other Studies

4 other studies available for prazosin and Liver Diseases

ArticleYear
Sympathetic nervous system inhibition increases hepatic progenitors and reduces liver injury.
    Hepatology (Baltimore, Md.), 2003, Volume: 38, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Antioxidants; Body Weight; Diet; Fatty Liver; Hepatocytes; Li

2003
Protection against paracetamol-induced hepatic injury by prazosin pre-treatment in CD-1 mice.
    Mutation research, 2005, Nov-11, Volume: 579, Issue:1-2

    Topics: Acetaminophen; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alanine Transaminase; Analge

2005
alpha(1)-Adrenoceptor antagonists prevent paracetamol-induced hepatotoxicity in mice.
    British journal of pharmacology, 2008, Volume: 153, Issue:4

    Topics: Acetaminophen; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Catec

2008
Hepatic necrosis induced by norepinephrine in rabbits.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1987, Volume: 185, Issue:4

    Topics: Alanine Transaminase; Animals; Calcium; Chemical and Drug Induced Liver Injury; Liver; Liver Disease

1987