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prazosin and Kidney Failure, Chronic

prazosin has been researched along with Kidney Failure, Chronic in 20 studies

Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.

Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.

Research Excerpts

ExcerptRelevanceReference
"Prazosin (Minipress; Pfizer), a new antihypertensive agent, was investigated in 24 outpatients with uncontrolled hypertension."9.04Prazosin in the therapy of uncontrolled hypertension. ( Lubbe, WF, 1977)
"Priapism developed during antihypertensive therapy with prazosin, 3-10 mg daily for 2-4 months, in two young men with severe renal failure."7.66Priapism--side-effect of prazosin in patients with renal failure. ( Pasternack, A; Ylitalo, P, 1983)
"Prazosin (Minipress; Pfizer), a new antihypertensive agent, was investigated in 24 outpatients with uncontrolled hypertension."5.04Prazosin in the therapy of uncontrolled hypertension. ( Lubbe, WF, 1977)
" In this article, doxazosin is reviewed for its efficacy in the treatment of severe essential hypertension and specific complications or conditions of mild or moderate essential hypertension, namely, left ventricular hypertrophy, hyperlipidemia, noninsulin-dependent diabetes mellitus, renal insufficiency, pheochromocytoma, chronic obstructive pulmonary disease, peripheral vascular disease, and smoking."4.78Efficacy of doxazosin in specific hypertensive patient groups. ( Taylor, SH, 1991)
"Priapism developed during antihypertensive therapy with prazosin, 3-10 mg daily for 2-4 months, in two young men with severe renal failure."3.66Priapism--side-effect of prazosin in patients with renal failure. ( Pasternack, A; Ylitalo, P, 1983)
"Terazosin is a new, long-acting, selective, postsynaptic alpha 1-adrenergic receptor antagonist with a chemical structure similar to that of prazosin."2.38Terazosin: pharmacokinetics and the effect of age and dose on the incidence of adverse events. ( Achari, R; Laddu, AR; Somberg, JC, 1991)
"Thus, functional bladder neck obstruction was considered to be responsible for obstructive voiding in these patients."1.29Functional bladder neck obstruction: a rare cause of renal failure. ( Banerjee, GK; Bhandari, M; Goel, MC; Kapoor, R; Kumar, A; Mishra, VK, 1995)
" After one dosage with a directly acting venodilator (nitroglycerin 5 mg s."1.28Compliance and reactivity of the peripheral venous system in chronic intermittent hemodialysis. ( Draaijer, P; Gladziwa, U; Kooman, JP; Leunissen, KM; Peltenburg, HG; Struyker-Boudier, HA; van Bortel, LM; van Hooff, JP; Wijnen, JA, 1992)
" The plasma half-life of terazosin in patients with normal renal function was 10."1.27Influence of renal insufficiency on the pharmacokinetics and pharmacodynamics of terazosin. ( Chauveau, P; Ganeval, D; Jungers, P; Pertuiset, N, 1986)
"Doxazosin was not appreciably dialyzable."1.27Pharmacokinetics and effect on blood pressure of doxazosin in normal subjects and patients with renal failure. ( Bailey, RR; Begg, EJ; Carlson, RV; Cowlishaw, MG; Sharman, JR, 1986)
"Pharmacokinetic parameters of prazosin (t1/2, tmax, Cmax and AUC have been studied in 18 hypertensive patients with varying degrees of chronic renal failure (serum creatinine ranging from 1."1.27A pharmacokinetic study of prazosin in patients with varying degrees of chronic renal failure. ( Gordts, J; Lameire, N, 1986)
" The rate of absorption of prazosin was identical in the two groups (t max: I,3 +/- 0,2 h and I,6 +/- 0,4 h)."1.26[Clinical pharmacology of prazosin in arterial hypertension with chronic renal insufficiency]. ( Aubert, P; Chaignon, M; Flouvat, B; Guédon, J; Le Roux, E; Lucsko, M, 1981)
"Prazosin absorption was not altered in patients with impaired renal function, and there is no cumulation of the drug when given repeatedly to patients with impaired renal function."1.26Prazosin kinetics and effectiveness in renal failure. ( Affrime, MB; Hobbs, D; Lowenthal, DT; Martinez, EW; Onesti, G; Twomey, TM, 1980)
" The enhanced antihypertensive effect of prazosin in renal failure appears to reflect changes in the bioavailability or distribution of the drug, which result in higher drug concentrations for a given dose."1.26Responsiveness to prazosin in renal failure. ( Frost, GW; MacCarthy, EP; Monaghan, JC; Stokes, GS, 1979)
"Prazosin was used as an additional antihypertensive agent for treating 38 patients with hypertension and renal functional impairment."1.26Prazosin in the treatment of patients with hypertension and renal functional impairment. ( Bailey, RR, 1977)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199014 (70.00)18.7374
1990's6 (30.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ylitalo, P1
Pasternack, A1
Chopra, JS1
Parkash, C1
Chhabra, R1
Wadhwa, NK1
Meltzer, VN1
Goldberg, AP1
Tindira, CA1
Naumovich, AD1
Harter, HR1
Chaignon, M1
Le Roux, E1
Aubert, P1
Lucsko, M1
Flouvat, B1
Guédon, J1
Rubin, P1
Blaschke, T1
Lowenthal, DT1
Hobbs, D1
Affrime, MB1
Twomey, TM1
Martinez, EW1
Onesti, G1
Kumar, A1
Banerjee, GK1
Goel, MC1
Mishra, VK1
Kapoor, R1
Bhandari, M1
Lubbe, WF1
Stokes, GS1
Monaghan, JC1
Frost, GW1
MacCarthy, EP1
Bailey, RR2
Kooman, JP1
Wijnen, JA1
Draaijer, P1
van Bortel, LM1
Gladziwa, U1
Peltenburg, HG1
Struyker-Boudier, HA1
van Hooff, JP1
Leunissen, KM1
Makó, J1
Potyondi, M1
Somberg, JC1
Achari, R1
Laddu, AR1
Taylor, SH1
Kiberd, BA1
Jungers, P1
Ganeval, D1
Pertuiset, N1
Chauveau, P1
Carlson, RV1
Begg, EJ1
Cowlishaw, MG1
Sharman, JR1
Chin, DK1
Ho, AK1
Tse, CY1
Lameire, N1
Gordts, J1
Kutsenko, AI1
Zaruba, AIu1
Arabidze, GG1
Kukharchuk, VV1
Mal'ginov, SV1

Reviews

2 reviews available for prazosin and Kidney Failure, Chronic

ArticleYear
Terazosin: pharmacokinetics and the effect of age and dose on the incidence of adverse events.
    American heart journal, 1991, Volume: 122, Issue:3 Pt 2

    Topics: Adrenergic alpha-Antagonists; Age Factors; Antihypertensive Agents; Dose-Response Relationship, Drug

1991
Efficacy of doxazosin in specific hypertensive patient groups.
    American heart journal, 1991, Volume: 121, Issue:1 Pt 2

    Topics: Adrenal Gland Neoplasms; Antihypertensive Agents; Cardiomegaly; Diabetes Mellitus, Type 2; Doxazosin

1991

Trials

1 trial available for prazosin and Kidney Failure, Chronic

ArticleYear
Prazosin in the therapy of uncontrolled hypertension.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1977, Nov-26, Volume: 52, Issue:23

    Topics: Adult; Aged; Clinical Trials as Topic; Creatinine; Female; Humans; Hypertension; Hypotension, Orthos

1977

Other Studies

17 other studies available for prazosin and Kidney Failure, Chronic

ArticleYear
Priapism--side-effect of prazosin in patients with renal failure.
    Acta medica Scandinavica, 1983, Volume: 213, Issue:4

    Topics: Adult; Glomerulonephritis; Humans; Hypertension, Renal; Kidney Failure, Chronic; Male; Prazosin; Pri

1983
Prazosin in hypertension associated with chronic renal failure.
    The Journal of the Association of Physicians of India, 1983, Volume: 31, Issue:3

    Topics: Adolescent; Adult; Follow-Up Studies; Humans; Hypertension; Kidney; Kidney Failure, Chronic; Middle

1983
Effects of prazosin and propranolol on blood pressure and plasma lipids in patients undergoing chronic hemodialysis.
    The American journal of cardiology, 1984, Jan-27, Volume: 53, Issue:3

    Topics: Adult; Blood Pressure; Cholesterol; Cholesterol, HDL; Female; Humans; Hypertension, Renal; Kidney Fa

1984
[Clinical pharmacology of prazosin in arterial hypertension with chronic renal insufficiency].
    Archives des maladies du coeur et des vaisseaux, 1981, Volume: 74 Spec No

    Topics: Adult; Aged; Blood Pressure; Female; Heart Rate; Humans; Hypertension, Renal; Kidney Failure, Chroni

1981
Prazosin protein binding in health and disease.
    British journal of clinical pharmacology, 1980, Volume: 9, Issue:2

    Topics: Adult; Blood Proteins; Erythrocytes; Female; Heart Failure; Humans; In Vitro Techniques; Kidney Fail

1980
Prazosin kinetics and effectiveness in renal failure.
    Clinical pharmacology and therapeutics, 1980, Volume: 27, Issue:6

    Topics: Adult; Aged; Blood Pressure; Blood Proteins; Dose-Response Relationship, Drug; Female; Humans; Hyper

1980
Functional bladder neck obstruction: a rare cause of renal failure.
    The Journal of urology, 1995, Volume: 154, Issue:1

    Topics: Adult; Catheters, Indwelling; Creatinine; Electromyography; Female; Follow-Up Studies; Humans; Kidne

1995
Responsiveness to prazosin in renal failure.
    Clinical science (London, England : 1979), 1979, Volume: 57 Suppl 5

    Topics: Adult; Aged; Blood Pressure; Humans; Hypertension; Kidney Failure, Chronic; Middle Aged; Posture; Pr

1979
Prazosin in the treatment of patients with hypertension and renal functional impairment.
    The Medical journal of Australia, 1977, Aug-27, Volume: 2, Issue:2 Suppl

    Topics: Female; Glomerular Filtration Rate; Humans; Hypertension, Renal; Kidney Failure, Chronic; Male; Midd

1977
Compliance and reactivity of the peripheral venous system in chronic intermittent hemodialysis.
    Kidney international, 1992, Volume: 41, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Blood Pressure; Compliance; Doxazosin; Female; Humans; Hy

1992
Use of Tensiomin in hypertensive patients with impaired renal function.
    Therapia Hungarica (English edition), 1992, Volume: 40, Issue:1

    Topics: Adult; Captopril; Creatinine; Humans; Hydralazine; Hypertension; Kidney; Kidney Failure, Chronic; Mi

1992
Effects of prazosin therapy in renal allograft recipients receiving cyclosporine.
    Transplantation, 1990, Volume: 49, Issue:6

    Topics: Cyclosporins; Humans; Kidney Failure, Chronic; Kidney Transplantation; Pilot Projects; Postoperative

1990
Influence of renal insufficiency on the pharmacokinetics and pharmacodynamics of terazosin.
    The American journal of medicine, 1986, May-23, Volume: 80, Issue:5B

    Topics: Adrenergic alpha-Antagonists; Adult; Blood Pressure; Female; Half-Life; Humans; Kidney Failure, Chro

1986
Pharmacokinetics and effect on blood pressure of doxazosin in normal subjects and patients with renal failure.
    Clinical pharmacology and therapeutics, 1986, Volume: 40, Issue:5

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Doxazosin; F

1986
Neuropsychiatric complications related to use of prazosin in patients with renal failure.
    British medical journal (Clinical research ed.), 1986, Nov-22, Volume: 293, Issue:6558

    Topics: Adult; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Prazosin; Substance-Related Disor

1986
A pharmacokinetic study of prazosin in patients with varying degrees of chronic renal failure.
    European journal of clinical pharmacology, 1986, Volume: 31, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Female; Half-Life; Humans;

1986
[Hemodialysis in patients with incorrigible arterial hypertension].
    Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR, 1985, Volume: 8, Issue:1

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Captopril; Female; Glomerulonephritis; Humans; Hyper

1985