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prazosin and Kidney Diseases

prazosin has been researched along with Kidney Diseases in 14 studies

Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.

Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.

Research Excerpts

ExcerptRelevanceReference
" The pharmacokinetics of doxazosin, following a single oral dose (1 mg) and chronic oral dosing (doubling doses up to a maximum of 16 mg day-1), were studied in 18 patients with mild to moderate hypertension and stable renal function varying from normal to severely impaired."7.68The pharmacokinetics of doxazosin in patients with hypertension and renal impairment. ( Dewhurst, AG; Honeywell, R; Oliver, RM; Renwick, AG; Upward, JW; Waller, DG, 1990)
"The pharmacokinetics of prazosin (Minipress) were studied in nine patients with NYHA Class 3 or 4 congestive heart failure and in five healthy controls."7.66Altered prazosin pharmacokinetics in congestive heart failure. ( Arnold, S; Baughman, RA; Benet, LZ; Chatterjee, K; Lin, ET; Williams, RL, 1980)
"Prazosin was used as an additional antihypertensive agent for treating 16 patients with hypertension and significant renal functional impairment."7.65Prazosin in the treatment of patients with hypertension and renal functional impairment. ( Bailey, RR; Little, PJ; Lynn, KL; Neale, TL, 1976)
" The pharmacokinetics of doxazosin, following a single oral dose (1 mg) and chronic oral dosing (doubling doses up to a maximum of 16 mg day-1), were studied in 18 patients with mild to moderate hypertension and stable renal function varying from normal to severely impaired."3.68The pharmacokinetics of doxazosin in patients with hypertension and renal impairment. ( Dewhurst, AG; Honeywell, R; Oliver, RM; Renwick, AG; Upward, JW; Waller, DG, 1990)
"The pharmacokinetics of prazosin (Minipress) were studied in nine patients with NYHA Class 3 or 4 congestive heart failure and in five healthy controls."3.66Altered prazosin pharmacokinetics in congestive heart failure. ( Arnold, S; Baughman, RA; Benet, LZ; Chatterjee, K; Lin, ET; Williams, RL, 1980)
"Prazosin was used as an additional antihypertensive agent for treating 16 patients with hypertension and significant renal functional impairment."3.65Prazosin in the treatment of patients with hypertension and renal functional impairment. ( Bailey, RR; Little, PJ; Lynn, KL; Neale, TL, 1976)
"To establish the effects of alpha-adrenoceptor blockade on dopamine-induced changes in renal hemodynamics and sodium excretion, dopamine dose-response curves were performed without and with pretreatment with the selective postsynaptic alpha 1-adrenoceptor antagonist prazosin in normal volunteers and in patients with renal disease and moderately impaired renal function."1.28The effects of alpha-adrenoceptor blockade on dopamine-induced renal vasodilation and natriuresis. ( Donker, AJ; Meijer, S; Reitsma, WD; Smit, AJ; Wesseling, H, 1991)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199010 (71.43)18.7374
1990's4 (28.57)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gunnells, JC1
Harter, HR1
Delmez, JA1
Kopstein, J1
Garcez, DM1
Baughman, RA1
Arnold, S1
Benet, LZ1
Lin, ET1
Chatterjee, K1
Williams, RL1
Vorburger, C1
Brogden, RN1
Heel, RC1
Speight, TM1
Avery, GS1
Bailey, RR1
Lynn, KL1
Neale, TL1
Little, PJ1
Rosenberg, ME1
Hostetter, TH1
Smit, AJ1
Meijer, S1
Wesseling, H1
Donker, AJ2
Reitsma, WD1
Oliver, RM2
Upward, JW1
Dewhurst, AG1
Honeywell, R1
Renwick, AG1
Waller, DG2
Bartels, AC1
de Vries, PM1
Oe, LP1
van Bronswÿk, H1
Réveillaud, RJ1
Fillastre, JP1
Zech, P1
Rambausek, M1
Ritz, E1
Mall, G1
Mehls, O1
Katus, H1
Wood, M1

Reviews

2 reviews available for prazosin and Kidney Diseases

ArticleYear
Prazosin: a review of its pharmacological properties and therapeutic efficacy in hypertension.
    Drugs, 1977, Volume: 14, Issue:3

    Topics: Animals; Benzothiadiazines; Blood Pressure; Clinical Trials as Topic; Diuretics; Drug Eruptions; Dru

1977
Plasma drug binding: implications for anesthesiologists.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:7

    Topics: Age Factors; Alfentanil; Alprenolol; Anesthesia; Anesthetics; Blood Proteins; Bupivacaine; Burns; Ca

1986

Trials

2 trials available for prazosin and Kidney Diseases

ArticleYear
Prazosin: a review of its pharmacological properties and therapeutic efficacy in hypertension.
    Drugs, 1977, Volume: 14, Issue:3

    Topics: Animals; Benzothiadiazines; Blood Pressure; Clinical Trials as Topic; Diuretics; Drug Eruptions; Dru

1977
Comparative effects of antihypertensives on proteinuria: angiotensin-converting enzyme inhibitor versus alpha 1-antagonist.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1991, Volume: 18, Issue:4

    Topics: Adult; Blood Pressure; Enalapril; Female; Glomerular Filtration Rate; Humans; Kidney; Kidney Disease

1991

Other Studies

11 other studies available for prazosin and Kidney Diseases

ArticleYear
Treating the patient with mild hypertension and renal insufficiency.
    The American journal of cardiology, 1983, Feb-24, Volume: 51, Issue:4

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Diuretics; Humans; Hypertensio

1983
[Effects of prazosin on the control of arterial pressure in hypertensive patients subjected to dialysis].
    Cardiology, 1980, Volume: 66 Suppl 2

    Topics: Blood Volume; Female; Humans; Hypertension; Kidney Diseases; Male; Middle Aged; Prazosin; Quinazolin

1980
[Prazosin in the treatment of arterial hypertension].
    Cardiology, 1980, Volume: 66 Suppl 2

    Topics: Adult; Antihypertensive Agents; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension;

1980
Altered prazosin pharmacokinetics in congestive heart failure.
    European journal of clinical pharmacology, 1980, Volume: 17, Issue:6

    Topics: Adult; Aged; Female; Heart Failure; Humans; Kidney Diseases; Kinetics; Liver; Male; Metabolic Cleara

1980
[Side effects of antihypertensive drugs].
    Schweizerische medizinische Wochenschrift, 1978, Jan-28, Volume: 108, Issue:4

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Benzothiadiazines; Blood Pressure; Diabetes Me

1978
Prazosin in the treatment of patients with hypertension and renal functional impairment.
    The New Zealand medical journal, 1976, Dec-22, Volume: 84, Issue:578

    Topics: Female; Humans; Hypertension; Kidney Diseases; Male; Middle Aged; Prazosin; Quinazolines

1976
The effects of alpha-adrenoceptor blockade on dopamine-induced renal vasodilation and natriuresis.
    Naunyn-Schmiedeberg's archives of pharmacology, 1991, Volume: 343, Issue:2

    Topics: Adult; Blood Pressure; Dopamine Antagonists; Female; Humans; Kidney; Kidney Diseases; Kidney Functio

1991
The pharmacokinetics of doxazosin in patients with hypertension and renal impairment.
    British journal of clinical pharmacology, 1990, Volume: 29, Issue:4

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Doxazosin; F

1990
Doxazosin in renal impairment.
    Journal of human hypertension, 1990, Volume: 4 Suppl 3

    Topics: Administration, Oral; Doxazosin; Drug Administration Schedule; Glomerular Filtration Rate; Half-Life

1990
Doxazosin in the treatment of patients with mild or moderate hypertension and mild or moderate renal insufficiency.
    American heart journal, 1988, Volume: 116, Issue:6 Pt 2

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Coronary Disease

1988
Myocardial hypertrophy in rats with renal insufficiency.
    Kidney international, 1985, Volume: 28, Issue:5

    Topics: Adenosine Triphosphatases; Animals; Blood Pressure; Blood Transfusion; Calcium; Cardiomegaly; Hydral

1985