prazosin has been researched along with Intraocular Pressure in 9 studies
Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.
Intraocular Pressure: The pressure of the fluids in the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| "1 mg (base) dose of prazosin, a postsynaptic alpha- (alpha 1) adrenoceptor antagonist, in rabbits effected an early decrease in arterial blood pressure, normal intraocular pressure (IOP) and IOP artificially elevated by water loading." | 7.66 | The effects of topical prazosin on normal and elevated intraocular pressure and blood pressure in rabbits. ( Potter, DE; Rowland, JM, 1980) |
| "Prazosin hydrochloride, an oral antihypertensive, is reported to inhibit phosphodiesterase and block postsynaptic alpha-adrenergic receptors, intraocular pressure (IOP) in rabbits was reduced in a dose-related manner following topical ocular application of concentrations of 0." | 7.66 | Influence of topically applied prazosin on the intraocular pressure of experimental animals. ( Leopold, IH; Murray, DL; Smith, BR, 1979) |
| ") administration of phenylephrine, clonidine, guanfacine, prazosin, yohimbine on the intraocular pressure (IOP) was investigated in the rabbit." | 3.68 | [Ocular hypotensive effect of alpha-adrenoceptor agonist and antagonist in the conscious pigmented rabbit]. ( Fukado, Y; Iizuka, T; Inatomi, M; Koide, R; Masaoka, Y; Moriwaki, Y; Nakamura, A; Nakata, K; Uchida, E; Ueda, T, 1992) |
| "1 mg (base) dose of prazosin, a postsynaptic alpha- (alpha 1) adrenoceptor antagonist, in rabbits effected an early decrease in arterial blood pressure, normal intraocular pressure (IOP) and IOP artificially elevated by water loading." | 3.66 | The effects of topical prazosin on normal and elevated intraocular pressure and blood pressure in rabbits. ( Potter, DE; Rowland, JM, 1980) |
| "Prazosin hydrochloride, a systemic antihypertensive agent, lowers intraocular pressure when applied topically to normal rabbit eyes." | 3.66 | Effect of prazosin on aqueous humor dynamics in rabbits. ( Becker, B; Feitl, M; Krupin, T, 1980) |
| "Prazosin hydrochloride, an oral antihypertensive, is reported to inhibit phosphodiesterase and block postsynaptic alpha-adrenergic receptors, intraocular pressure (IOP) in rabbits was reduced in a dose-related manner following topical ocular application of concentrations of 0." | 3.66 | Influence of topically applied prazosin on the intraocular pressure of experimental animals. ( Leopold, IH; Murray, DL; Smith, BR, 1979) |
| "Methysergide seems to inhibit the response, probably acting via the 5-HT1-receptors." | 1.27 | Effect of alpha-adrenergic and serotonergic blockers on the acute irritative response in the rabbit eye. ( Krootila, K; Palkama, A; Uusitalo, H, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (66.67) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, J | 1 |
| Song, Y | 1 |
| Ren, B | 1 |
| Sun, N | 1 |
| Yu, Y | 1 |
| Hu, H | 1 |
| Chiou, GC | 1 |
| Rowland, JM | 1 |
| Potter, DE | 1 |
| Krupin, T | 1 |
| Feitl, M | 1 |
| Becker, B | 1 |
| Smith, BR | 1 |
| Murray, DL | 1 |
| Leopold, IH | 1 |
| Moriwaki, Y | 1 |
| Iizuka, T | 1 |
| Nakamura, A | 1 |
| Nakata, K | 1 |
| Masaoka, Y | 1 |
| Ueda, T | 1 |
| Koide, R | 1 |
| Inatomi, M | 1 |
| Fukado, Y | 1 |
| Uchida, E | 1 |
| Myhre, K | 1 |
| Brinchmann-Hansen, O | 1 |
| Mittag, TW | 1 |
| Tormay, A | 1 |
| Severin, C | 1 |
| Podos, SM | 1 |
| Krootila, K | 1 |
| Uusitalo, H | 1 |
| Palkama, A | 1 |
9 other studies available for prazosin and Intraocular Pressure
| Article | Year |
|---|---|
Different effects of topical prazosin and pilocarpine on uveoscleral outflow in rabbit eyes.
Topics: Administration, Topical; Adrenergic alpha-Antagonists; Animals; Aqueous Humor; Female; Intraocular P | 2003 |
Effects of alpha 1 and alpha 2 activation of adrenergic receptors on aqueous humor dynamics.
Topics: Animals; Aqueous Humor; Cats; Clonidine; Intraocular Pressure; Phenylephrine; Prazosin; Receptors, A | 1983 |
The effects of topical prazosin on normal and elevated intraocular pressure and blood pressure in rabbits.
Topics: Administration, Topical; Animals; Blood Pressure; Intraocular Pressure; Male; Prazosin; Quinazolines | 1980 |
Effect of prazosin on aqueous humor dynamics in rabbits.
Topics: Administration, Topical; Animals; Aqueous Humor; Ascorbic Acid; Blood Pressure; Intraocular Pressure | 1980 |
Influence of topically applied prazosin on the intraocular pressure of experimental animals.
Topics: Administration, Topical; Anesthesia, General; Animals; Blood Pressure Determination; Cornea; Dose-Re | 1979 |
[Ocular hypotensive effect of alpha-adrenoceptor agonist and antagonist in the conscious pigmented rabbit].
Topics: Administration, Topical; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cerebral | 1992 |
Prolonged photostress macular recovery after reduced blood pressure.
Topics: Adaptation, Physiological; Adult; Aerospace Medicine; Antihypertensive Agents; Blood Pressure; Doxaz | 1991 |
Alpha-adrenergic antagonists: correlation of the effect on intraocular pressure and on alpha 2-adrenergic receptor binding specificity in the rabbit eye.
Topics: Adrenergic alpha-Antagonists; Animals; Ciliary Body; Dioxanes; Intraocular Pressure; Iris; Membranes | 1985 |
Effect of alpha-adrenergic and serotonergic blockers on the acute irritative response in the rabbit eye.
Topics: Adrenergic alpha-Antagonists; Animals; Aqueous Humor; Blood Pressure; Eye Diseases; Eye Proteins; Fe | 1987 |