prazosin has been researched along with Inadequate Sleep in 12 studies
Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Such sleep fragmentation is coincident with an impairment of baroreflex sensitivity, and is mediated via α1-adernoceptors." | 1.39 | Unstable sleep and higher sympathetic activity during late-sleep periods of rats: implication for late-sleep-related higher cardiovascular events. ( Chen, CY; Kuo, TB; Lai, CT; Lee, GS; Yang, CC, 2013) |
| "treatment of prazosin, an alpha1-adrenpceptor antagonist, as well as in vitro membranes prepared from neurons and glia separated from normal rat brain." | 1.35 | REM sleep deprivation-induced noradrenaline stimulates neuronal and inhibits glial Na-K ATPase in rat brain: in vivo and in vitro studies. ( Baskey, G; Mallick, BN; Sharma, R; Singh, A, 2009) |
| "Prolonged rapid eye movement sleep deprivation (REMSD) causes hypothermia and death; however, the effect of deprivation within 24 h and its mechanism(s) of action were unknown." | 1.35 | Prazosin modulates rapid eye movement sleep deprivation-induced changes in body temperature in rats. ( Jaiswal, MK; Mallick, BN, 2009) |
| "Rapid eye movement sleep deprivation increases Na-K ATPase activity and decreases aminergic neuronal firing rate as well as norepinephrine degrading enzyme, monoamine oxidase, activity." | 1.29 | Possible mechanism of rapid eye movement sleep deprivation induced increase in Na-K ATPase activity. ( Gulyani, S; Mallick, BN, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (16.67) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 5 (41.67) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Ranjan, A | 2 |
| Biswas, S | 2 |
| Mallick, BN | 6 |
| DeWeerdt, S | 1 |
| Lai, CT | 2 |
| Chen, CY | 2 |
| Kuo, TB | 2 |
| Chern, CM | 1 |
| Yang, CC | 2 |
| Baskey, G | 1 |
| Singh, A | 1 |
| Sharma, R | 1 |
| Jaiswal, MK | 1 |
| Singh, S | 1 |
| Amar, M | 1 |
| Lee, GS | 1 |
| Gulyani, S | 1 |
| Hipólide, DC | 1 |
| Tufik, S | 1 |
| Raymond, R | 1 |
| Nobrega, JN | 1 |
| Aalto, J | 1 |
| Kiianmaa, K | 1 |
| Mogilnicka, E | 1 |
| Przewłocka, B | 1 |
| Van Luijtelaar, EL | 1 |
| Klimek, V | 1 |
| Coenen, AM | 1 |
1 review available for prazosin and Inadequate Sleep
| Article | Year |
|---|---|
Rapid eye movement sleep loss associated cytomorphometric changes and neurodegeneration.
Topics: Animals; Artificial Intelligence; Brain; Humans; Mammals; Prazosin; Sleep Deprivation; Sleep, REM | 2023 |
11 other studies available for prazosin and Inadequate Sleep
| Article | Year |
|---|---|
Mood disorders: the dark night.
Topics: Affect; Amygdala; Bipolar Disorder; Circadian Rhythm; Depression; Dreams; Electroencephalography; Gy | 2013 |
Sympathetic Hyperactivity, Sleep Fragmentation, and Wake-Related Blood Pressure Surge During Late-Light Sleep in Spontaneously Hypertensive Rats.
Topics: Activity Cycles; Adrenergic alpha-1 Receptor Antagonists; Animals; Antihypertensive Agents; Barorefl | 2016 |
REM sleep deprivation-induced noradrenaline stimulates neuronal and inhibits glial Na-K ATPase in rat brain: in vivo and in vitro studies.
Topics: Adenosine Triphosphatases; Animals; Brain; Cation Transport Proteins; Cell Line; Male; Neuroglia; Ne | 2009 |
Prazosin modulates rapid eye movement sleep deprivation-induced changes in body temperature in rats.
Topics: Adrenergic alpha-Antagonists; Animals; Body Temperature Regulation; Injections, Intraperitoneal; Mal | 2009 |
Cytomorphometric changes in the dorsal raphe neurons after rapid eye movement sleep deprivation are mediated by noradrenalin in rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Inferior Colliculi; Male; Neurons; Norepinephrine; | 2010 |
Rapid eye movement sleep deprivation modulates synapsinI expression in rat brain.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Brain; Male; Phosphorylation; Prazosin; Rats; Rats | 2012 |
Unstable sleep and higher sympathetic activity during late-sleep periods of rats: implication for late-sleep-related higher cardiovascular events.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-1 Receptor Antagonists; Animals; Atenolol; | 2013 |
Possible mechanism of rapid eye movement sleep deprivation induced increase in Na-K ATPase activity.
Topics: Adrenergic Agonists; Adrenergic Antagonists; Animals; Dose-Response Relationship, Drug; Male; Norepi | 1995 |
Heterogeneous effects of rapid eye movement sleep deprivation on binding to alpha- and beta-adrenergic receptor subtypes in rat brain.
Topics: Animals; Autoradiography; Brain; Brimonidine Tartrate; Iodine Radioisotopes; Kinetics; Male; Organ S | 1998 |
Role of brain monoaminergic systems in the increased ethanol drinking caused by REM-sleep deprivation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Animals; Brain Chemistry; Catecholamines; Citalopr | 1987 |
Effects of REM sleep deprivation on central alpha 1- and beta-adrenoceptors in rat brain.
Topics: Animals; Antidepressive Agents, Tricyclic; Cerebral Cortex; Dihydroalprenolol; Ligands; Male; Prazos | 1986 |