prazosin has been researched along with Hypotension in 53 studies
Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.
Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was designed to evaluate the safety and efficacy of the selective alpha 1-adrenoceptor blocker terazosin in the treatment of benign prostatic hyperplasia (BPH)." | 9.08 | A multicenter, randomized, double-blind, placebo-controlled study to evaluate the safety and efficacy of terazosin in the treatment of benign prostatic hyperplasia. ( Barkin, J; Beland, G; Boake, RC; Casey, RW; Elhilali, MM; Fradet, Y; Klotz, LH; Orovan, WL; Ramsey, EW; Schick, E; Trachtenberg, J, 1996) |
| "To examine the clinical usefulness of selective and non-selective alpha 1-adrenoceptor antagonists, we compared a selective (tamsulosin) and non-selective (terazosin) alpha 1-adrenoceptor antagonists in the treatment of Chinese patients with benign prostatic hyperplasia (BPH)." | 9.08 | Clinical comparison of selective and non-selective alpha 1A-adrenoceptor antagonists for bladder outlet obstruction associated with benign prostatic hyperplasia: studies on tamsulosin and terazosin in Chinese patients. The Chinese Tamsulosin Study Group. ( Gu, FL; Guo, YL; Na, YJ, 1998) |
| "In this report, we assess the safety of terazosin in the treatment of patients with symptomatic benign prostatic hyperplasia." | 8.79 | Side effects of terazosin in the treatment of symptomatic benign prostatic hyperplasia. ( Lowe, FC; McKiernan, JM, 1997) |
| "The oral angiotensin-converting enzyme inhibitor captopril (CPT) produces beneficial hemodynamic and clinical responses in patients with chronic congestive heart failure (CHF)." | 7.66 | Captopril in congestive heart failure: improved left ventricular function with decreased metabolic cost. ( Chatterjee, K; Parmley, WW; Rouleau, JL, 1982) |
| "Prazosin's increase in popularity as a treatment for posttraumatic stress disorder makes it important for emergency physicians to be aware of how to manage potential toxic ingestion because of prazosin overdose." | 6.58 | Refractory Hypotension Caused by Prazosin Overdose Combined With Acetaminophen and Naproxen Toxicity: A Case Report and Review of the Literature. ( Anderson, C; Gupta, R; Lim, RK; Lynch, T, 2018) |
| "choline can increase blood pressure in rats made hypotensive by acute chemical sympathectomy through the activation of central nicotinic receptors by presynaptic mechanisms." | 5.30 | Intracerebroventricular choline reverses hypotension induced by acute chemical sympathectomy. ( Gürün, MS; Savci, V; Ulus, IH, 1997) |
| "This study was designed to evaluate the safety and efficacy of the selective alpha 1-adrenoceptor blocker terazosin in the treatment of benign prostatic hyperplasia (BPH)." | 5.08 | A multicenter, randomized, double-blind, placebo-controlled study to evaluate the safety and efficacy of terazosin in the treatment of benign prostatic hyperplasia. ( Barkin, J; Beland, G; Boake, RC; Casey, RW; Elhilali, MM; Fradet, Y; Klotz, LH; Orovan, WL; Ramsey, EW; Schick, E; Trachtenberg, J, 1996) |
| "To examine the clinical usefulness of selective and non-selective alpha 1-adrenoceptor antagonists, we compared a selective (tamsulosin) and non-selective (terazosin) alpha 1-adrenoceptor antagonists in the treatment of Chinese patients with benign prostatic hyperplasia (BPH)." | 5.08 | Clinical comparison of selective and non-selective alpha 1A-adrenoceptor antagonists for bladder outlet obstruction associated with benign prostatic hyperplasia: studies on tamsulosin and terazosin in Chinese patients. The Chinese Tamsulosin Study Group. ( Gu, FL; Guo, YL; Na, YJ, 1998) |
| "In this report, we assess the safety of terazosin in the treatment of patients with symptomatic benign prostatic hyperplasia." | 4.79 | Side effects of terazosin in the treatment of symptomatic benign prostatic hyperplasia. ( Lowe, FC; McKiernan, JM, 1997) |
| " This study was designed to compare middle cerebral artery mean blood velocity responses to acute hypotension with and without alpha(1)-adrenoreceptor blockade (Prazosin) in young, healthy humans." | 3.74 | Autonomic neural control of the cerebral vasculature: acute hypotension. ( Brothers, RM; Eubank, WL; Ogoh, S; Raven, PB, 2008) |
| " Prazosin injection produced hypotension and tachycardia in both groups (C=-43+/-3 mm Hg/98+/-16 bpm; SW=-61+/-5 mm Hg/115+/-32 bpm)." | 3.73 | Attenuated pressor responses to amino acids in the rostral ventrolateral medulla after swimming training in conscious rats. ( Basso, LS; Becker, LK; de Souza, HC; Garcia, MR; Lopes, OU; Martins-Pinge, MC; Neto, RV; Zoccal, DB, 2005) |
| " The reversal of hypotension by THA was greatly attenuated by administration of either prazosin, an alpha(1)-adrenoceptor antagonist (0." | 3.71 | Reversal of Haemorrhagic Shock in Rats by Tetrahydroaminoacridine. ( Cavun, S; Gürün, MS; Savci, V; Ulus, IH, 2001) |
| "Treatment of benign prostatic hyperplasia (BPH) with nonselective alpha1 antagonists such as terazosin, doxazosin, and prazosin results in blood pressure reduction due to vasodilation." | 3.71 | Initiation of nonselective alpha1-antagonist therapy and occurrence of hypotension-related adverse events among men with benign prostatic hyperplasia: a retrospective cohort study. ( Chao, J; Chrischilles, E; Gilden, D; Kreder, KJ; Rubenstein, L; Shah, H, 2001) |
| "The ectoparasiticide amitraz stimulates alpha 2-adrenoceptors to produce side-effects such as bradycardia and hypotension." | 3.69 | Amitraz depresses cardiovascular responses to bilateral carotid occlusion. ( Cullen, LK; Reynoldson, JA, 1996) |
| "The hypothesis that central alpha-1 adrenoceptors are inhibitory to the hypotension-induced secretion of vasopressin was tested by subjecting lambs that were instrumented for a long term to varying degrees of hypotension after intracerebroventricular injections of prazosin or placebo." | 3.68 | Central alpha-1-adrenergic control of vasopressin secretion in newborn lambs. ( Barnes, KD; Block, SM; Zoltoski, R, 1991) |
| "Our objectives were 1) to investigate the extent to which the pulmonary vascular response to increasing cardiac index after a period of hypotension and hypoperfusion (defined as reperfusion) measured in conscious dogs is altered during pentobarbital sodium anesthesia, and 2) to determine whether pentobarbital anesthesia modifies autonomic nervous system (ANS) regulation of the pulmonary circulation during reperfusion." | 3.67 | Pentobarbital anesthesia modifies pulmonary vasoregulation after hypoperfusion. ( Chen, BB; Clougherty, PW; Fehr, DM; Goll, HM; Murray, PA; Nyhan, DP, 1988) |
| " Indomethacin treatment (5 mg/kg ia) of piglets following hemorrhage caused a significant decrease in blood flow to all brain regions within 20 min." | 3.67 | Adrenergic and prostanoid mechanisms in control of cerebral blood flow in hypotensive newborn pigs. ( Armstead, WM; Beasley, DG; Busija, DW; Leffler, CW; Mirro, R, 1988) |
| "The oral angiotensin-converting enzyme inhibitor captopril (CPT) produces beneficial hemodynamic and clinical responses in patients with chronic congestive heart failure (CHF)." | 3.66 | Captopril in congestive heart failure: improved left ventricular function with decreased metabolic cost. ( Chatterjee, K; Parmley, WW; Rouleau, JL, 1982) |
| "Prazosin's increase in popularity as a treatment for posttraumatic stress disorder makes it important for emergency physicians to be aware of how to manage potential toxic ingestion because of prazosin overdose." | 2.58 | Refractory Hypotension Caused by Prazosin Overdose Combined With Acetaminophen and Naproxen Toxicity: A Case Report and Review of the Literature. ( Anderson, C; Gupta, R; Lim, RK; Lynch, T, 2018) |
| " These compounds, when dosed of 1." | 1.42 | α-Adrenoceptor antagonistic and hypotensive properties of novel arylpiperazine derivatives of pyrrolidin-2-one. ( Bednarski, M; Dudek, M; Kulig, K; Lustyk, K; Malawska, B; Nowiński, L; Raźny, K; Sapa, J; Siwek, A; Starowicz, G; Zaręba, P, 2015) |
| "Anaphylactic shock is sometimes life-threatening, and it is accompanied by hepatic venoconstriction in animals, which, in part, accounts for anaphylactic hypotension." | 1.39 | Alpha-adrenoceptor antagonists and chemical sympathectomy exacerbate anaphylaxis-induced hypotension, but not portal hypertension, in anesthetized rats. ( Kurata, Y; Shibamoto, T; Tanida, M; Wang, M, 2013) |
| "Prazosin treatment prolonged the duration of NTG-induced MAP response by about 4-fold for all NTG doses examined (P < 0." | 1.32 | Prazosin potentiates the acute hypotensive effects of nitroglycerin but does not attenuate nitrate tolerance in normal conscious rats. ( Fung, HL; Wang, EQ, 2004) |
| "choline can increase blood pressure in rats made hypotensive by acute chemical sympathectomy through the activation of central nicotinic receptors by presynaptic mechanisms." | 1.30 | Intracerebroventricular choline reverses hypotension induced by acute chemical sympathectomy. ( Gürün, MS; Savci, V; Ulus, IH, 1997) |
| "Arterial hypotension can cause cerebral ischemia when the autoregulation of the cerebral circulation is exhausted." | 1.30 | Cerebral vasoconstriction during sustained ventricular tachycardia induces an ischemic stress response of brain tissue in rats. ( Danos, P; Dettmers, C; Hagendorff, A; Heusch, G; Hümmelgen, M; Lüderitz, B; Martin, C; Vahlhaus, C, 1998) |
| "5 mm Hg per ng/ml when prazosin was combined with verapamil (p less than 0." | 1.28 | An additive or synergistic drug interaction: application of concentration-effect modeling. ( Elliott, HL; Meredith, PA, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (37.74) | 18.7374 |
| 1990's | 15 (28.30) | 18.2507 |
| 2000's | 10 (18.87) | 29.6817 |
| 2010's | 8 (15.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zaręba, P | 1 |
| Dudek, M | 1 |
| Lustyk, K | 1 |
| Siwek, A | 1 |
| Starowicz, G | 1 |
| Bednarski, M | 1 |
| Nowiński, L | 1 |
| Raźny, K | 1 |
| Sapa, J | 1 |
| Malawska, B | 1 |
| Kulig, K | 1 |
| Anderson, C | 1 |
| Lynch, T | 1 |
| Gupta, R | 1 |
| Lim, RK | 1 |
| Iwai, T | 1 |
| Kaneko, M | 1 |
| Sasaki-Hamada, S | 1 |
| Oka, J | 1 |
| Wang, M | 1 |
| Tanida, M | 1 |
| Shibamoto, T | 1 |
| Kurata, Y | 1 |
| Agrawal, R | 1 |
| Mishra, SK | 1 |
| Bhatia, E | 1 |
| Mishra, A | 1 |
| Chand, G | 1 |
| Agarwal, G | 1 |
| Agarwal, A | 1 |
| Verma, AK | 1 |
| Wahab, NA | 1 |
| Zainudin, S | 1 |
| AbAziz, A | 1 |
| Kamaruddin, NA | 1 |
| Ogoh, S | 2 |
| Sørensen, H | 1 |
| Hirasawa, A | 1 |
| Sasaki, H | 1 |
| Washio, T | 1 |
| Hashimoto, T | 1 |
| Bailey, DM | 1 |
| Secher, NH | 1 |
| Belayneh, M | 1 |
| Korownyk, C | 1 |
| Prakash, ES | 1 |
| Mathis, KW | 1 |
| Molina, PE | 1 |
| Wang, EQ | 1 |
| Fung, HL | 1 |
| Valdivia, LF | 1 |
| Centurión, D | 1 |
| Arulmani, U | 1 |
| Saxena, PR | 1 |
| Villalón, CM | 1 |
| Martins-Pinge, MC | 1 |
| Becker, LK | 1 |
| Garcia, MR | 1 |
| Zoccal, DB | 1 |
| Neto, RV | 1 |
| Basso, LS | 1 |
| de Souza, HC | 1 |
| Lopes, OU | 1 |
| Jochem, J | 1 |
| Zwirska-Korczala, K | 1 |
| Zabielski, R | 1 |
| Kato, I | 1 |
| Kuwahara, A | 1 |
| Brothers, RM | 1 |
| Eubank, WL | 1 |
| Raven, PB | 1 |
| Hamilton, TC | 1 |
| Hunt, AA | 1 |
| Poyser, RH | 1 |
| Roquebert, J | 1 |
| Demichel, P | 1 |
| Malek, A | 1 |
| Chatterjee, K | 1 |
| Rouleau, JL | 1 |
| Parmley, WW | 1 |
| Jee, LD | 1 |
| Opie, LH | 1 |
| Rubin, PC | 1 |
| Brunton, J | 1 |
| Meredith, P | 1 |
| Gerber, JG | 1 |
| Nies, AS | 1 |
| Olson, RD | 1 |
| Glass, AR | 1 |
| Ballou, R | 1 |
| Baum, T | 1 |
| Sabin, C | 1 |
| Moran, RM | 1 |
| Sugimoto, T | 1 |
| Hosoki, K | 1 |
| Karasawa, T | 1 |
| Lydiatt, CA | 1 |
| Fee, MP | 1 |
| Hill, GE | 1 |
| Elhilali, MM | 1 |
| Ramsey, EW | 1 |
| Barkin, J | 1 |
| Casey, RW | 1 |
| Boake, RC | 1 |
| Beland, G | 1 |
| Fradet, Y | 1 |
| Trachtenberg, J | 1 |
| Orovan, WL | 1 |
| Schick, E | 1 |
| Klotz, LH | 1 |
| Reynoldson, JA | 1 |
| Cullen, LK | 1 |
| Dunbar, JC | 1 |
| O'Leary, DS | 1 |
| Wang, G | 1 |
| Wright-Richey, J | 1 |
| McKiernan, JM | 1 |
| Lowe, FC | 1 |
| Gürün, MS | 2 |
| Savci, V | 2 |
| Ulus, IH | 2 |
| Hagendorff, A | 1 |
| Dettmers, C | 1 |
| Danos, P | 1 |
| Hümmelgen, M | 1 |
| Vahlhaus, C | 1 |
| Martin, C | 1 |
| Heusch, G | 1 |
| Lüderitz, B | 1 |
| Na, YJ | 1 |
| Guo, YL | 1 |
| Gu, FL | 1 |
| Iversen, PL | 1 |
| Cornish, KG | 1 |
| Iversen, LJ | 1 |
| Mata, JE | 1 |
| Bylund, DB | 1 |
| Cavun, S | 1 |
| Chrischilles, E | 1 |
| Rubenstein, L | 1 |
| Chao, J | 1 |
| Kreder, KJ | 1 |
| Gilden, D | 1 |
| Shah, H | 1 |
| Takakura, K | 1 |
| Taniguchi, T | 1 |
| Muramatsu, I | 1 |
| Takeuchi, K | 1 |
| Fukuda, S | 1 |
| Moulds, RJ | 1 |
| Jauernig, RA | 1 |
| Imhof, P | 1 |
| Bendall, MJ | 1 |
| Meredith, PA | 1 |
| Elliott, HL | 1 |
| Block, SM | 1 |
| Barnes, KD | 1 |
| Zoltoski, R | 1 |
| Hasford, J | 2 |
| Bussmann, WD | 2 |
| Delius, W | 2 |
| Koepcke, W | 1 |
| Lehmann, K | 2 |
| Weber, E | 2 |
| Zhang, C | 1 |
| Hsueh, W | 1 |
| Köpcke, W | 1 |
| Jeffries, WB | 1 |
| Tam, LT | 1 |
| Wang, Y | 1 |
| Smyth, DD | 1 |
| Pettinger, WA | 1 |
| Feldman, T | 1 |
| Carroll, JD | 1 |
| Munkenbeck, F | 1 |
| Alibali, P | 1 |
| Feldman, M | 1 |
| Coggins, DL | 1 |
| Gray, KR | 1 |
| Bump, T | 1 |
| Chen, BB | 1 |
| Nyhan, DP | 1 |
| Goll, HM | 1 |
| Clougherty, PW | 1 |
| Fehr, DM | 1 |
| Murray, PA | 1 |
| Jordan, DA | 1 |
| Breslow, MJ | 1 |
| Kubos, KL | 1 |
| Traystman, RJ | 1 |
| Bond, RF | 2 |
| Johnson, G | 2 |
| Jones, CE | 1 |
| Liang, IY | 1 |
| Maulsby, MR | 1 |
| Armstead, WM | 1 |
| Leffler, CW | 1 |
| Busija, DW | 1 |
| Beasley, DG | 1 |
| Mirro, R | 1 |
| Lin, MS | 1 |
| Hsieh, WJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Role of Shear Stress in the Cerebrovascular Response to Acute Exercise[NCT03722953] | 18 participants (Actual) | Interventional | 2018-12-01 | Completed | |||
| The Effects of Systemic Alfuzosin and Tamsulosin Hydrochloride on Choroidal Thickness and Pupil Diameter Sizes in Cases With Benign Prostatic Hyperplasia[NCT03144596] | Phase 4 | 63 participants (Actual) | Interventional | 2015-10-29 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for prazosin and Hypotension
| Article | Year |
|---|---|
Refractory Hypotension Caused by Prazosin Overdose Combined With Acetaminophen and Naproxen Toxicity: A Case Report and Review of the Literature.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antihy | 2018 |
Treatment of lower urinary tract symptoms in benign prostatic hypertrophy with α-blockers.
Topics: Adrenergic alpha-Antagonists; Dizziness; Doxazosin; Humans; Hypotension; Lower Urinary Tract Symptom | 2016 |
Side effects of terazosin in the treatment of symptomatic benign prostatic hyperplasia.
Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Clinical Trials as Topic; Dizziness; Humans; | 1997 |
[Treatment of cardiac failure with vasodilators (author's transl)].
Topics: Cardiac Glycosides; Diuretics; Drug Therapy, Combination; Heart Failure; Hydralazine; Hypotension; I | 1978 |
5 trials available for prazosin and Hypotension
| Article | Year |
|---|---|
Prospective study to compare peri-operative hemodynamic alterations following preparation for pheochromocytoma surgery by phenoxybenzamine or prazosin.
Topics: Adrenal Gland Neoplasms; Adrenergic alpha-Antagonists; Adult; Blood Pressure; Female; Heart Rate; He | 2014 |
A multicenter, randomized, double-blind, placebo-controlled study to evaluate the safety and efficacy of terazosin in the treatment of benign prostatic hyperplasia.
Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Analysis of Variance; Canada; Double-Blind Me | 1996 |
Clinical comparison of selective and non-selective alpha 1A-adrenoceptor antagonists for bladder outlet obstruction associated with benign prostatic hyperplasia: studies on tamsulosin and terazosin in Chinese patients. The Chinese Tamsulosin Study Group.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Aged; Dose-Response Relations | 1998 |
First dose hypotension with enalapril and prazosin in congestive heart failure.
Topics: Aged; Drug Evaluation; Enalapril; Female; Follow-Up Studies; Heart Failure; Humans; Hypotension; Log | 1991 |
Design and analysis of the HYPREN-trial: safety of enalapril and prazosin in the initial treatment phase of patients with congestive heart failure.
Topics: Aged; Enalapril; Female; Heart Failure; Hemodynamics; Humans; Hypotension; Male; Prazosin | 1991 |
44 other studies available for prazosin and Hypotension
| Article | Year |
|---|---|
α-Adrenoceptor antagonistic and hypotensive properties of novel arylpiperazine derivatives of pyrrolidin-2-one.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Dose-Response Relationship, Drug; Hypotension; Mal | 2015 |
Characterization of the hypotensive effects of glucagon-like peptide-2 in anesthetized rats.
Topics: Animals; Antihypertensive Agents; Arterial Pressure; Atropine; Glucagon-Like Peptide 2; Hypotension; | 2013 |
Alpha-adrenoceptor antagonists and chemical sympathectomy exacerbate anaphylaxis-induced hypotension, but not portal hypertension, in anesthetized rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Anaphylaxis; Animals; Hypertension, Portal; Hypotension; Li | 2013 |
Utility of alpha-blockade in a hypotensive pheochromocytoma patient with myocardial infarction.
Topics: Adrenal Gland Neoplasms; Adrenergic alpha-1 Receptor Antagonists; Adult; Echocardiography; Humans; H | 2015 |
Dynamic cerebral autoregulation is unrelated to decrease in external carotid artery blood flow during acute hypotension in healthy young men.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Arterial Pressure; Carotid Artery, External; Carotid | 2016 |
Effect of prazosin on dynamic cerebral autoregulation during acute hypotension in healthy human subjects.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cerebral Cortex; Cerebrovascular Circulation; Home | 2008 |
Central acetylcholinesterase inhibition improves hemodynamic counterregulation to severe blood loss in alcohol-intoxicated rats.
Topics: Alcoholic Intoxication; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Bl | 2009 |
Prazosin potentiates the acute hypotensive effects of nitroglycerin but does not attenuate nitrate tolerance in normal conscious rats.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Drug Synergism; Drug Tolerance; Hypotension; | 2004 |
5-HT1B receptors, alpha2A/2C- and, to a lesser extent, alpha1-adrenoceptors mediate the external carotid vasoconstriction to ergotamine in vagosympathectomised dogs.
Topics: Animals; Biphenyl Compounds; Blood Pressure; Carotid Artery, External; Dogs; Dose-Response Relations | 2004 |
Attenuated pressor responses to amino acids in the rostral ventrolateral medulla after swimming training in conscious rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiovascular System; Consciousness; Dose-Respons | 2005 |
Cardiovascular effects of centrally acting orexin A in haemorrhage-shocked rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Cardiovascular S | 2006 |
Autonomic neural control of the cerebral vasculature: acute hypotension.
Topics: Administration, Oral; Adult; Autonomic Nervous System; Blood Pressure; Cerebrovascular Circulation; | 2008 |
Involvement of central alpha 2-adrenoceptors in the mediation of clonidine-induced hypotension in the cat.
Topics: Animals; Blood Pressure; Cats; Clonidine; Female; Hypotension; Prazosin; Receptors, Adrenergic; Rece | 1980 |
Effects of thymoxamine and its metabolites on clonidine-induced hypotension and bradycardia in rats.
Topics: Anesthesia; Animals; Blood Pressure; Bradycardia; Clonidine; Heart Rate; Hypotension; Male; Moxisyly | 1982 |
Captopril in congestive heart failure: improved left ventricular function with decreased metabolic cost.
Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Heart Failure; Heart Ventricles; Hemodynamics; | 1982 |
Acute hypotensive response to nifedipine added to prazosin in treatment of hypertension.
Topics: Adult; Drug Therapy, Combination; Humans; Hypertension; Hypotension; Male; Nifedipine; Prazosin; Qui | 1983 |
Determination of the vasodilator UK33274 by high-performance liquid chromatography using fluorescence detection.
Topics: Chromatography, High Pressure Liquid; Doxazosin; Humans; Hypotension; Prazosin; Quinazolines; Vasodi | 1980 |
Prazosin does not alter canine renin release in response to systemic hypotension or intrarenal isoprenaline and prostaglandin I2 infusion.
Topics: Animals; Dogs; Epoprostenol; Hemodynamics; Hypotension; Infusions, Parenteral; Isoproterenol; Kidney | 1980 |
Pheochromocytoma, prazosin, and hypotension.
Topics: Adrenal Gland Neoplasms; Female; Humans; Hypotension; Middle Aged; Pheochromocytoma; Prazosin; Quina | 1982 |
Comparison of hypotensive, orthostatic and sympathetic inhibitory actions of antihypertensive drugs in rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Diazepam; Guanethidine; Heart Rate; Hyd | 1981 |
Relative contribution of alpha 1-adrenoceptor blocking activity to the hypotensive effect of the novel calcium antagonist monatepil.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Calc | 1995 |
Severe hypotension during epidural anesthesia in a prazosin-treated patient.
Topics: Anesthesia, Epidural; Epinephrine; Humans; Hypotension; Male; Middle Aged; Phenylephrine; Prazosin; | 1993 |
Amitraz depresses cardiovascular responses to bilateral carotid occlusion.
Topics: Animals; Baroreflex; Blood Pressure; Bradycardia; Carotid Arteries; Carotid Stenosis; Dogs; Dose-Res | 1996 |
Mechanisms mediating insulin-induced hypotension in rats. A role for nitric oxide and autonomic mediators.
Topics: Animals; Antihypertensive Agents; Atenolol; Atropine; Autonomic Nervous System; Blood Glucose; Blood | 1996 |
Intracerebroventricular choline reverses hypotension induced by acute chemical sympathectomy.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Choline; Cholinergic Antagonists; Dose-Respon | 1997 |
Cerebral vasoconstriction during sustained ventricular tachycardia induces an ischemic stress response of brain tissue in rats.
Topics: Adrenergic alpha-Antagonists; Animals; Brain; Brain Ischemia; Cerebrovascular Circulation; Epinephri | 1998 |
Bolus intravenous injection of phosphorothioate oligonucleotides causes hypotension by acting as alpha(1)-adrenergic receptor antagonists.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Cell Membrane; Cerebral Cortex; Heart Atria; Heart | 1999 |
Reversal of Haemorrhagic Shock in Rats by Tetrahydroaminoacridine.
Topics: Adrenergic alpha-Antagonists; Anesthetics, Intravenous; Animals; Antidiuretic Hormone Receptor Antag | 2001 |
Initiation of nonselective alpha1-antagonist therapy and occurrence of hypotension-related adverse events among men with benign prostatic hyperplasia: a retrospective cohort study.
Topics: Accidental Falls; Adrenergic alpha-Antagonists; Aged; Antihypertensive Agents; Cohort Studies; Comor | 2001 |
Modification of alpha1 -adrenoceptors by peroxynitrite as a possible mechanism of systemic hypotension in sepsis.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Calcium; CHO Cells; Cricetinae; Hypotension; In Vitro | 2002 |
Mechanism of prazosin collapse.
Topics: Adrenergic alpha-Antagonists; Arteries; Dose-Response Relationship, Drug; Humans; Hypotension; In Vi | 1977 |
Side effects of prazocin.
Topics: Blood Pressure; Humans; Hypotension; Prazosin; Quinazolines; Research Design | 1976 |
An additive or synergistic drug interaction: application of concentration-effect modeling.
Topics: Adult; Blood Pressure; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Drug The | 1992 |
Central alpha-1-adrenergic control of vasopressin secretion in newborn lambs.
Topics: Animals; Animals, Newborn; Arginine Vasopressin; Blood Pressure; Dose-Response Relationship, Drug; H | 1991 |
PAF-induced bowel necrosis. Effects of vasodilators.
Topics: Alprostadil; Animals; Hydralazine; Hypotension; Indazoles; Intestinal Diseases; Leukopenia; Male; Me | 1991 |
Prazosin-induced alterations in renal alpha-adrenergic receptor function.
Topics: Adrenergic beta-Agonists; Animals; Cocaine; Electric Stimulation; Hypotension; In Vitro Techniques; | 1987 |
Hemodynamic recovery during simulated ventricular tachycardia: role of adrenergic receptor activation.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Cardiac Pacing, Artificial; Dise | 1988 |
Pentobarbital anesthesia modifies pulmonary vasoregulation after hypoperfusion.
Topics: Acetylcholine; Anesthesia, General; Animals; Autonomic Nervous System; Blood Pressure; Cardiac Outpu | 1988 |
Adrenergic receptors of adrenal medullary vasculature.
Topics: Adrenal Medulla; Animals; Catecholamines; Dogs; Hemorrhage; Hypotension; Microspheres; Pindolol; Pra | 1989 |
Alpha 1- and alpha 2-adrenoreceptor relationships in SHRs during hypotension.
Topics: Adrenal Medulla; Animals; Blood Pressure; Hypotension; Male; Prazosin; Pressoreceptors; Propranolol; | 1985 |
Cardiac and coronary effects of prazosin and phenoxybenzamine during coronary hypotension.
Topics: Animals; Coronary Circulation; Dogs; Female; Heart; Hypotension; Male; Oxygen Consumption; Phenoxybe | 1986 |
Adrenergic and prostanoid mechanisms in control of cerebral blood flow in hypotensive newborn pigs.
Topics: Animals; Animals, Newborn; Blood Pressure; Brain; Carbon Dioxide; Cerebrovascular Circulation; Hemor | 1988 |
Prazosin-induced first-dose phenomenon possibly associated with hemorrhagic stroke: a report of three cases.
Topics: Cerebral Hemorrhage; Cerebrovascular Disorders; Dose-Response Relationship, Drug; Female; Humans; Hy | 1987 |
Cardiovascular adrenoreceptor balance during hemorrhagic hypotension and shock.
Topics: Animals; Cyclooxygenase Inhibitors; Hypotension; Male; Meclofenamic Acid; Prazosin; Rats; Rats, Inbr | 1985 |