prazosin has been researched along with Hypertrophy, Left Ventricular in 10 studies
Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.
Hypertrophy, Left Ventricular: Enlargement of the LEFT VENTRICLE of the heart. This increase in ventricular mass is attributed to sustained abnormal pressure or volume loads and is a contributor to cardiovascular morbidity and mortality.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Twenty five unmedicated patients with primary hypertension were randomised to initial therapy with either the calcium antagonist, felodipine, or a diuretic and doses titrated to achieve similar levels of blood pressure (BP)." | 5.08 | Assessment of effects of two anti-hypertensive regimens on overall cardiovascular risk. ( Jennings, GL; Korner, P; Laufer, E; Reid, C; Sudhir, K, 1995) |
| "Patients with mild to moderate hypertension (diastolic blood pressure, 95 to 109 mm Hg) were randomly allocated to treatment with atenolol, captopril, clonidine, diltiazem, hydrochlorothiazide, or prazosin in a double-masked trial." | 5.08 | Effect of single-drug therapy on reduction of left ventricular mass in mild to moderate hypertension: comparison of six antihypertensive agents. The Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents. ( Anderson, RJ; Gottdiener, JS; Massie, BM; Materson, BJ; Reda, DJ; Williams, DW, 1997) |
| "We examined the acute effects of elevated wall stress, norepinephrine, and angiotensin II on cardiac protein synthesis as well as protooncogene expression in hearts with established pressure overload left ventricular hypertrophy." | 3.69 | Alteration of growth responses in established cardiac pressure overload hypertrophy in rats with aortic banding. ( Bruckschlegel, G; Lorell, BH; Riegger, AJ; Schunkert, H; Weinberg, EO, 1995) |
| "CARDIOVASCULAR RISK OF LEFT VENTRICULAR HYPERTROPHY: Because of the rhythmic, mechanical and ischemic risk related to it, the left ventricular hypertrophy (LVH) is considered to be a major independent risk factor for cardiovascular disease which should be screened for and treated early." | 2.70 | [Management of hypertensive patients with left ventricular hypertrophy]. ( Ambrosioni, E, 2002) |
| "High sodium diet (HS, 8% NaCl) induces left ventricular hypertrophy (LVH) in normotensive rats without an increase in pressure or volume load or in resting cardiac sympathetic activity." | 1.30 | alpha- and beta-adrenoceptor blockade fail to prevent high sodium diet-induced left ventricular hypertrophy. ( Harmsen, E; Leenen, FH; Song, D, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (60.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ambrosioni, E | 1 |
| Kamblock, J | 1 |
| N'Guyen, L | 1 |
| Pagis, B | 1 |
| Costes, P | 1 |
| Le Goanvic, C | 1 |
| Lionet, P | 1 |
| Maheu, B | 1 |
| Papouin, G | 1 |
| Imai, C | 1 |
| Tozawa, M | 1 |
| Sunagawa, O | 1 |
| Muratani, H | 1 |
| Takishita, S | 1 |
| Fukiyama, K | 1 |
| Jennings, GL | 1 |
| Sudhir, K | 1 |
| Laufer, E | 1 |
| Korner, P | 1 |
| Reid, C | 1 |
| Ram, CV | 1 |
| Schunkert, H | 1 |
| Weinberg, EO | 1 |
| Bruckschlegel, G | 1 |
| Riegger, AJ | 1 |
| Lorell, BH | 1 |
| Gottdiener, JS | 1 |
| Reda, DJ | 1 |
| Massie, BM | 1 |
| Materson, BJ | 1 |
| Williams, DW | 1 |
| Anderson, RJ | 1 |
| Song, D | 1 |
| Harmsen, E | 1 |
| Leenen, FH | 1 |
| Grimm, D | 1 |
| Huber, M | 1 |
| Jabusch, HC | 1 |
| Shakibaei, M | 1 |
| Fredersdorf, S | 1 |
| Paul, M | 1 |
| Riegger, GA | 1 |
| Kromer, EP | 1 |
| Rassler, B | 1 |
| Barth, W | 1 |
| Zimmer, HG | 1 |
1 review available for prazosin and Hypertrophy, Left Ventricular
| Article | Year |
|---|---|
Adrenergic mechanisms in left ventricular hypertrophy: significance and clinical implications.
Topics: Adrenergic alpha-Antagonists; Animals; Arrhythmias, Cardiac; Blood Pressure; Hemodynamics; Humans; H | 1993 |
3 trials available for prazosin and Hypertrophy, Left Ventricular
| Article | Year |
|---|---|
[Management of hypertensive patients with left ventricular hypertrophy].
Topics: Adrenergic alpha-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agent | 2002 |
Assessment of effects of two anti-hypertensive regimens on overall cardiovascular risk.
Topics: Adolescent; Adult; Aged; Blood Pressure; Cardiovascular Diseases; Cholesterol; Diuretics; Drug Thera | 1995 |
Effect of single-drug therapy on reduction of left ventricular mass in mild to moderate hypertension: comparison of six antihypertensive agents. The Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhib | 1997 |
6 other studies available for prazosin and Hypertrophy, Left Ventricular
| Article | Year |
|---|---|
Acute severe mitral regurgitation during first attacks of rheumatic fever: clinical spectrum, mechanisms and prognostic factors.
Topics: Acute Disease; Adrenal Cortex Hormones; Adrenergic alpha-Antagonists; Angiotensin-Converting Enzyme | 2005 |
Alterations of alpha 1-adrenergic receptor densities in right and left ventricles of spontaneously hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Body Weight; Dogs; Heart Ventricles; Hyperten | 1995 |
Alteration of growth responses in established cardiac pressure overload hypertrophy in rats with aortic banding.
Topics: Angiotensin II; Animals; Aorta; Gene Expression; Heart; Hemodynamics; Hypertrophy, Left Ventricular; | 1995 |
alpha- and beta-adrenoceptor blockade fail to prevent high sodium diet-induced left ventricular hypertrophy.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Body Weight; Dri | 1997 |
Extracellular matrix proteins in cardiac fibroblasts derived from rat hearts with chronic pressure overload: effects of beta-receptor blockade.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Antihypertensive Agent | 2001 |
Transient pleural effusion in norepinephrine-stimulated rats.
Topics: Animals; Antihypertensive Agents; Female; Heart Rate; Hypertrophy, Left Ventricular; Norepinephrine; | 2001 |