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prazosin and Hypertension, Renovascular

prazosin has been researched along with Hypertension, Renovascular in 12 studies

Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.

Hypertension, Renovascular: Hypertension due to RENAL ARTERY OBSTRUCTION or compression.

Research Excerpts

ExcerptRelevanceReference
"As chronic hypertension shifts the lower limit of cerebral blood flow (CBF) autoregulation to higher pressure levels, we studied the effects of the angiotensin converting enzyme (ACE) inhibitor, perindopril on mean arterial pressure (mean BP), basal CBF, and CBF autoregulation in awake renovascular hypertensive (2 kidneys, 1 clip model) and spontaneously hypertensive rats (SHR)."3.68Effects of the angiotensin I converting enzyme inhibitor perindopril on cerebral blood flow in awake hypertensive rats. ( Atkinson, J; Bray, L; Capdeville, C; Lartaud, I; Muller, F, 1991)
"To examine the relationships between the central and peripheral renin angiotensin system in normotensive Wistar Kyoto (WKY) rats, two-kidney, one-clip Goldblatt renovascular hypertension (RVH), spontaneously hypertensive rats (SHR), SQ 14225 (captopril) was administered intraventricularly (IVT) and intravenously (IV) in the alternative manner and their combination."3.67Central and peripheral contributions of the renin-angiotensin system in two models of experimental hypertension in rats. ( Itaya, Y; Kageyama, Y; Kondo, K; Matsukawa, S; Saruta, T; Suzuki, H, 1986)
" Both hypotensive agents shifted the dose-response curve to NE to the right."1.28Effect of ketanserin and prazosin on blood pressure and cardiovascular reactivity to vasopressor agents during the development of two kidney-two clip renal hypertension in the conscious rat. ( Basso, N; Kurnjek, M; Mikulic, L; Taquini, AC, 1989)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19909 (75.00)18.7374
1990's3 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Winters, G1
Sala, A1
Barone, D1
Baldoli, E1
Karlberg, BE1
Fyhrquist, F1
Grönhagen-Riska, C1
Tikkanen, I1
Ohman, KP1
Schiffrin, EL1
Mancinella, A1
Liuti, G1
Paolucci, M1
Baietti, M1
Carletta, C1
Hieble, JP1
Nichols, AJ1
Fredrickson, TA1
DePalma, PD1
Ruffolo, RR1
Brooks, DP1
Bray, L1
Lartaud, I1
Muller, F1
Atkinson, J1
Capdeville, C1
Hall, MT1
Wadsworth, RM1
Kane, KA1
Hamilton, CA1
Reid, JL1
Rodger, IW1
Kurnjek, M1
Basso, N1
Mikulic, L1
Taquini, AC1
McElroy, ND1
Zimmerman, BG2
Zeigler, DW1
Ramos, OL1
Suzuki, H1
Matsukawa, S1
Itaya, Y1
Kageyama, Y1
Saruta, T1
Kondo, K1

Trials

1 trial available for prazosin and Hypertension, Renovascular

ArticleYear
Enalapril and lisinopril in renovascular hypertension--antihypertensive and hormonal effects of two new angiotensin-converting-enzyme (ACE) inhibitors. A preliminary report.
    Scandinavian journal of urology and nephrology. Supplementum, 1984, Volume: 79

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive

1984

Other Studies

11 other studies available for prazosin and Hypertension, Renovascular

ArticleYear
Synthesis, in vitro [3H]prazosin displacement, and in vivo activity of 3-aryl-4,5,6,7-tetrahydropyrazolo[4,3-c]pyridines, a new class of antihypertensive agents.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:7

    Topics: Animals; Brain; Cats; Chemical Phenomena; Chemistry; Dogs; Hypertension; Hypertension, Renovascular;

1985
Alpha 1-adrenergic receptors in the mesenteric vascular bed of renal and spontaneously hypertensive rats.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1984, Volume: 2, Issue:3

    Topics: Animals; Hypertension, Renovascular; Male; Mesenteric Arteries; Prazosin; Radioligand Assay; Rats; R

1984
[Treatment of arterial hypertension in the aged].
    La Clinica terapeutica, 1978, Aug-31, Volume: 86, Issue:4

    Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Antihypertensive Agents; Clonidine; Diuretics; Human

1978
Cardiovascular actions of a new selective postjunctional alpha-adrenoceptor antagonist, SK&F 104856, in normotensive and hypertensive dogs.
    British journal of pharmacology, 1992, Volume: 105, Issue:4

    Topics: Adrenergic alpha-Antagonists; Animals; Benzazepines; Blood Pressure; Cardiovascular Physiological Ph

1992
Effects of the angiotensin I converting enzyme inhibitor perindopril on cerebral blood flow in awake hypertensive rats.
    American journal of hypertension, 1991, Volume: 4, Issue:3 Pt 2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cerebrovascular Circulation; Hemodynam

1991
Noradrenaline sensitivity and calcium fluxes in arteries from rabbits with perinephritis hypertension.
    Clinical and experimental pharmacology & physiology, 1990, Volume: 17, Issue:8

    Topics: Angiotensin II; Animals; Aorta; Calcium; Cocaine; Dioxanes; Hypertension, Renovascular; Idazoxan; Ki

1990
Effect of ketanserin and prazosin on blood pressure and cardiovascular reactivity to vasopressor agents during the development of two kidney-two clip renal hypertension in the conscious rat.
    Archives internationales de physiologie et de biochimie, 1989, Volume: 97, Issue:1

    Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Blood Pressure; Heart Rate; Hypertension, Ren

1989
Characterization of intrarenal arterial adrenergic receptors in renovascular hypertension.
    Hypertension (Dallas, Tex. : 1979), 1989, Volume: 13, Issue:6 Pt 2

    Topics: Animals; Binding Sites; Binding, Competitive; Hypertension, Renovascular; Male; Osmolar Concentratio

1989
Effect of alpha 1-adrenoceptor blockade on blood pressure and iliac vascular resistance in normotensive and Goldblatt hypertensive dogs; influence of dietary salt and DOCA-salt.
    Journal of hypertension, 1987, Volume: 5, Issue:4

    Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Captopril; Desoxycorticosterone; Dogs; Female

1987
Diabetes mellitus and hypertension. State of the art lecture.
    Hypertension (Dallas, Tex. : 1979), 1988, Volume: 11, Issue:2 Pt 2

    Topics: Angiotensin II; Animals; Blood Pressure; Captopril; Diabetes Mellitus, Experimental; Diabetes Mellit

1988
Central and peripheral contributions of the renin-angiotensin system in two models of experimental hypertension in rats.
    Clinical and experimental hypertension. Part A, Theory and practice, 1986, Volume: 8, Issue:1

    Topics: Animals; Blood Pressure; Brain; Captopril; Disease Models, Animal; Hypertension; Hypertension, Renov

1986