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prazosin and Hypertension, Pulmonary

prazosin has been researched along with Hypertension, Pulmonary in 15 studies

Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.

Hypertension, Pulmonary: Increased VASCULAR RESISTANCE in the PULMONARY CIRCULATION, usually secondary to HEART DISEASES or LUNG DISEASES.

Research Excerpts

ExcerptRelevanceReference
"A 51-year-old patient with COPD, obesity, and pulmonary hypertension underwent long-term prazosin therapy after a successful hemodynamic response to 1 mg of oral prazosin."7.68Long-term prazosin therapy for COPD pulmonary hypertension. ( Lewczuk, J; Piszko, P; Sobkowicz-Woźniak, B; Spikowski, J; Wrabec, K, 1992)
"The effect of vasodilator therapy in chronic obstructive lung disease with pulmonary hypertension was evaluated in eight patients during oral prazosin therapy (2-10 mg day-1)."7.67Improved haemodynamics but reduced arterial blood oxygenation, at rest and during exercise after long-term oral prazosin therapy in chronic cor pulmonale. ( Halvorsen, FJ; Jentoft, H; Vik-Mo, H; Walde, N, 1985)
"Prazosin was studied in 11 patients (10 men, 1 women) aged 63 +/- 7 years with advanced c."6.67[Clinical and hemodynamic evaluation of 6-week treatment of pulmonary hypertension in chronic obstructive lung diseases (COLD) with low dose of prazosin]. ( Lewczuk, J; Palka, PS; Piszko, P; Porada, A; Sobkowicz-Woźniak, B; Spikowski, J; Szczygielski, J; Trzesicka, M; Wrabec, K, 1990)
" During 12 weeks of prednisone treatment in a dosage of 40 mg daily, her condition markedly deteriorated clinically and hemodynamically as manifested by pulmonary artery pressure (PAP), pulmonary vascular resistance (PVR), cardiac output (CO), mixed venous O2 saturation, and systemic vascular resistance (SVR)."5.28Nifedipine and prazosin in the management of pulmonary hypertension in CREST syndrome. ( Dresner-Feigin, R; Galun, E; Glikson, M; Pollack, A; Rubinow, A, 1990)
"A single dose of capoten (25 mg) and prazosin (I mg) was given to 82 patients with stable pulmonary hypertension and chronic non-specific pulmonary diseases and to 34 patients with the above condition and arterial hypertension."5.06[Pharmacologic effects of peripheral vasodilators in patients with secondary pulmonary hypertension]. ( Abrosimov, AG; Belov, AM; Kukes, VG; Nasyrov, ShN; Tsoĭ, AN, 1989)
"The effect of monocrotaline-induced pulmonary hypertension on alpha(1)-adrenoceptor-mediated contractions of pulmonary artery segments was studied."3.72Alpha 1-adrenoceptor subtypes mediating noradrenaline-induced contraction of pulmonary artery from pulmonary hypertensive rats. ( Chandrasekhar, B; Kadavil, EA; Oriowo, MA, 2003)
"A 51-year-old patient with COPD, obesity, and pulmonary hypertension underwent long-term prazosin therapy after a successful hemodynamic response to 1 mg of oral prazosin."3.68Long-term prazosin therapy for COPD pulmonary hypertension. ( Lewczuk, J; Piszko, P; Sobkowicz-Woźniak, B; Spikowski, J; Wrabec, K, 1992)
"The effect of vasodilator therapy in chronic obstructive lung disease with pulmonary hypertension was evaluated in eight patients during oral prazosin therapy (2-10 mg day-1)."3.67Improved haemodynamics but reduced arterial blood oxygenation, at rest and during exercise after long-term oral prazosin therapy in chronic cor pulmonale. ( Halvorsen, FJ; Jentoft, H; Vik-Mo, H; Walde, N, 1985)
"Prazosin was studied in 11 patients (10 men, 1 women) aged 63 +/- 7 years with advanced c."2.67[Clinical and hemodynamic evaluation of 6-week treatment of pulmonary hypertension in chronic obstructive lung diseases (COLD) with low dose of prazosin]. ( Lewczuk, J; Palka, PS; Piszko, P; Porada, A; Sobkowicz-Woźniak, B; Spikowski, J; Szczygielski, J; Trzesicka, M; Wrabec, K, 1990)
" During 12 weeks of prednisone treatment in a dosage of 40 mg daily, her condition markedly deteriorated clinically and hemodynamically as manifested by pulmonary artery pressure (PAP), pulmonary vascular resistance (PVR), cardiac output (CO), mixed venous O2 saturation, and systemic vascular resistance (SVR)."1.28Nifedipine and prazosin in the management of pulmonary hypertension in CREST syndrome. ( Dresner-Feigin, R; Galun, E; Glikson, M; Pollack, A; Rubinow, A, 1990)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199010 (66.67)18.7374
1990's4 (26.67)18.2507
2000's1 (6.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Oriowo, MA1
Chandrasekhar, B1
Kadavil, EA1
Coma-Canella, I1
Lopez-Sendon, J1
Kanemoto, N3
Imaoka, C2
Goto, Y3
Hayashi, Y1
Ubukata, S1
Hojo, Y1
Elkayam, U1
Lewczuk, J3
Sobkowicz-Woźniak, B2
Piszko, P2
Spikowski, J2
Wrabec, K3
Porada, A1
Trzesicka, M1
Palka, PS1
Szczygielski, J1
Glikson, M1
Pollack, A1
Dresner-Feigin, R1
Galun, E1
Rubinow, A1
Yamaguchi, H1
Shiina, Y1
Kukes, VG1
Tsoĭ, AN1
Abrosimov, AG1
Nasyrov, ShN1
Belov, AM1
Powers, K1
Fyfe, DA1
Taylor, AB1
Halushka, PV1
Crawford, FA1
Funayama, N1
Takenaka, T1
Horimoto, M1
Igarashi, T1
Neild, TO1
McLean, JR1
Mee, RB1
Vik-Mo, H1
Walde, N1
Jentoft, H1
Halvorsen, FJ1

Reviews

1 review available for prazosin and Hypertension, Pulmonary

ArticleYear
[Value of vasodilator agents in the treatment of diseases with pulmonary hypertension caused by chronic obstructive lung diseases].
    Pneumonologia i alergologia polska, 1991, Volume: 59, Issue:3-4

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel B

1991

Trials

2 trials available for prazosin and Hypertension, Pulmonary

ArticleYear
[Clinical and hemodynamic evaluation of 6-week treatment of pulmonary hypertension in chronic obstructive lung diseases (COLD) with low dose of prazosin].
    Kardiologia polska, 1990, Volume: 33, Issue:6

    Topics: Administration, Oral; Aged; Hemodynamics; Humans; Hypertension, Pulmonary; Lung Diseases, Obstructiv

1990
[Pharmacologic effects of peripheral vasodilators in patients with secondary pulmonary hypertension].
    Klinicheskaia meditsina, 1989, Volume: 67, Issue:5

    Topics: Adolescent; Adult; Aged; Captopril; Clinical Trials as Topic; Hemodynamics; Humans; Hypertension, Pu

1989

Other Studies

12 other studies available for prazosin and Hypertension, Pulmonary

ArticleYear
Alpha 1-adrenoceptor subtypes mediating noradrenaline-induced contraction of pulmonary artery from pulmonary hypertensive rats.
    European journal of pharmacology, 2003, Dec-15, Volume: 482, Issue:1-3

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Animals; Dose-Respons

2003
Haemodynamic effects of nifedipine, nitroglycerine and prazosin in pulmonary hypertension following ingestion of toxic oil.
    European heart journal, 1983, Volume: 4, Issue:8

    Topics: Adolescent; Adult; Child; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Male; Middle Aged;

1983
A case of primary pulmonary hypertension treated with prazosin and isosorbide dinitrate.
    Japanese heart journal, 1984, Volume: 25, Issue:6

    Topics: Administration, Oral; Adult; Drug Therapy, Combination; Electrocardiography; Female; Humans; Hyperte

1984
[Primary pulmonary hypertension in a brother and a sister--combined administration of prazosin and isosorbide dinitrate].
    Kokyu to junkan. Respiration & circulation, 1983, Volume: 31, Issue:8

    Topics: Adult; Drug Combinations; Female; Humans; Hypertension, Pulmonary; Isosorbide Dinitrate; Male; Prazo

1983
Vasodilator therapy in primary pulmonary hypertension.
    Chest, 1981, Volume: 79, Issue:3

    Topics: Adult; Diazoxide; Female; Hemodynamics; Humans; Hydralazine; Hypertension, Pulmonary; Isoproterenol;

1981
Long-term prazosin therapy for COPD pulmonary hypertension.
    Chest, 1992, Volume: 102, Issue:2

    Topics: Humans; Hypertension, Pulmonary; Lung Diseases, Obstructive; Male; Middle Aged; Obesity; Prazosin; R

1992
Nifedipine and prazosin in the management of pulmonary hypertension in CREST syndrome.
    Chest, 1990, Volume: 98, Issue:3

    Topics: Adult; Drug Therapy, Combination; Esophageal Motility Disorders; Hemodynamics; Humans; Hypertension,

1990
Reversibility of primary pulmonary hypertension with vasodilator, anticoagulant and nocturnal oxygen therapy.
    Japanese heart journal, 1989, Volume: 30, Issue:6

    Topics: Adolescent; Combined Modality Therapy; Drug Therapy, Combination; Female; Humans; Hypertension, Pulm

1989
Treatment of pulmonary vasospasm with prazosin after atrial septal defect closure in a child.
    The Journal of thoracic and cardiovascular surgery, 1989, Volume: 97, Issue:5

    Topics: Heart Septal Defects; Humans; Hypertension, Pulmonary; Infant; Male; Postoperative Period; Prazosin

1989
[A case of primary pulmonary hypertension--acute and chronic effect of vasodilators].
    Kokyu to junkan. Respiration & circulation, 1987, Volume: 35, Issue:2

    Topics: Adult; Drug Therapy, Combination; Female; Humans; Hypertension, Pulmonary; Isosorbide Dinitrate; Pra

1987
An in vitro study of the pharmacological and electrophysiological properties and the adrenergic innervation of small pulmonary arteries from children with pulmonary hypertension.
    Research communications in chemical pathology and pharmacology, 1986, Volume: 53, Issue:2

    Topics: Acetylcholine; Catecholamines; Child; Child, Preschool; Dose-Response Relationship, Drug; Electric S

1986
Improved haemodynamics but reduced arterial blood oxygenation, at rest and during exercise after long-term oral prazosin therapy in chronic cor pulmonale.
    European heart journal, 1985, Volume: 6, Issue:12

    Topics: Administration, Oral; Aged; Carbon Dioxide; Chronic Disease; Female; Hemodynamics; Humans; Hypertens

1985