prazosin has been researched along with Hyperplasia in 4 studies
Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.
Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Prazosin-treated rabbits had significantly less luminal reduction at 1 week (0." | 5.28 | Role for prazosin in reducing the development of rabbit intimal hyperplasia after endothelial denudation. ( McDermott, EW; Mehigan, D; O'Higgins, NJ; O'Malley, MK, 1989) |
| " Standardized dose-response curves demonstrated that the injured tissue was increasingly sensitive over time to norepinephrine and that this was more marked at physiologic levels of norepinephrine." | 1.27 | Increased vascular contraction and sensitivity to norepinephrine after endothelial denudation is inhibited by prazosin. ( Cole, CW; Hagen, PO; McCann, RL; Mikat, EM; O'Malley, MK; Radic, ZS, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guh, JH | 1 |
| Chueh, SC | 1 |
| Ko, FN | 1 |
| Teng, CM | 1 |
| Norman, PE | 1 |
| House, AK | 1 |
| O'Malley, MK | 2 |
| McDermott, EW | 1 |
| Mehigan, D | 1 |
| O'Higgins, NJ | 1 |
| Hagen, PO | 1 |
| Mikat, EM | 1 |
| Cole, CW | 1 |
| Radic, ZS | 1 |
| McCann, RL | 1 |
4 other studies available for prazosin and Hyperplasia
| Article | Year |
|---|---|
Characterization of alpha 1-adrenoceptor subtypes in tension response of human prostate to electrical field stimulation.
Topics: Adrenergic Antagonists; Animals; Clonidine; Electric Stimulation; Humans; Hyperplasia; In Vitro Tech | 1995 |
Influence of prazosin on experimental vein graft intimal thickening.
Topics: Anastomosis, Surgical; Animals; Blood Vessel Prosthesis; Hyperplasia; Iliac Artery; Male; Prazosin; | 1992 |
Role for prazosin in reducing the development of rabbit intimal hyperplasia after endothelial denudation.
Topics: Animals; Aorta, Abdominal; Endothelium, Vascular; Hyperplasia; Muscle, Smooth, Vascular; Prazosin; R | 1989 |
Increased vascular contraction and sensitivity to norepinephrine after endothelial denudation is inhibited by prazosin.
Topics: Animals; Aorta, Abdominal; Catheterization; Dose-Response Relationship, Drug; Endothelium; Hyperplas | 1986 |