Page last updated: 2024-11-03

prazosin and Hemorrhagic Shock

prazosin has been researched along with Hemorrhagic Shock in 10 studies

Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.

Research Excerpts

ExcerptRelevanceReference
" The reversal of hypotension by THA was greatly attenuated by administration of either prazosin, an alpha(1)-adrenoceptor antagonist (0."3.71Reversal of Haemorrhagic Shock in Rats by Tetrahydroaminoacridine. ( Cavun, S; Gürün, MS; Savci, V; Ulus, IH, 2001)
" The role of alpha(1)-adrenergic stimulation in myocardial TNF-alpha expression and depressed cardiac function after HS/R was assessed by treatment with the alpha(1)-adrenergic inhibitor, prazosin hydrochloride (1 mg/kg ip), for 1 h before the onset of hemorrhage."3.71Hemorrhage-induced alpha-adrenergic signaling results in myocardial TNF-alpha expression and contractile dysfunction. ( Klein, LV; Lindsay, TF; Marshall, JG; Nicholson, S; Rubin, BB; Shahani, R; Walker, PM, 2001)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19904 (40.00)18.7374
1990's2 (20.00)18.2507
2000's4 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mathis, KW1
Molina, PE1
Jochem, J1
Zwirska-Korczala, K1
Zabielski, R1
Kato, I1
Kuwahara, A1
Bond, RF3
Johnson, G3
Liu, LM1
Chen, HS1
Hu, DY1
Lu, RQ1
Li, TX1
Savci, V1
Cavun, S1
Gürün, MS1
Ulus, IH1
Shahani, R1
Klein, LV1
Marshall, JG1
Nicholson, S1
Rubin, BB1
Walker, PM1
Lindsay, TF1
Schaumloffel, V1
Pugh, V1
Bealer, SL1
Edvinsson, L1
MacKenzie, ET1
Robert, JP1
Skärby, T1
Young, AR1

Other Studies

10 other studies available for prazosin and Hemorrhagic Shock

ArticleYear
Central acetylcholinesterase inhibition improves hemodynamic counterregulation to severe blood loss in alcohol-intoxicated rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 297, Issue:2

    Topics: Alcoholic Intoxication; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Bl

2009
Cardiovascular effects of centrally acting orexin A in haemorrhage-shocked rats.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2006, Volume: 57 Suppl 11

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Cardiovascular S

2006
Cardiovascular adrenoreceptor function during compensatory and decompensatory hemorrhagic shock.
    Circulatory shock, 1984, Volume: 12, Issue:1

    Topics: Animals; Hemodynamics; Levulinic Acids; Male; Phenoxybenzamine; Prazosin; Propranolol; Rats; Rats, I

1984
Effects of thyrotropin-releasing hormone on myocardial adrenoceptors and dopaminergic receptors following hemorrhagic shock in the rat.
    Shock (Augusta, Ga.), 1995, Volume: 3, Issue:6

    Topics: Animals; Cell Membrane; Female; Male; Myocardium; Prazosin; Radioligand Assay; Rats; Rats, Wistar; R

1995
Reversal of Haemorrhagic Shock in Rats by Tetrahydroaminoacridine.
    Pharmacology, 2001, Volume: 62, Issue:1

    Topics: Adrenergic alpha-Antagonists; Anesthetics, Intravenous; Animals; Antidiuretic Hormone Receptor Antag

2001
Hemorrhage-induced alpha-adrenergic signaling results in myocardial TNF-alpha expression and contractile dysfunction.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 281, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Hemorrhage; Male; Myocardial Contr

2001
Preoptic hypothalamic lesions reduce adrenergic vascular compensation during hemorrhagic shock.
    Circulatory shock, 1990, Volume: 31, Issue:2

    Topics: Animals; Hemodynamics; Male; Phentolamine; Prazosin; Preoptic Area; Rats; Rats, Inbred Strains; Rece

1990
Alpha 1- and alpha 2-adrenoreceptor relationships in SHRs during hypotension.
    Circulatory shock, 1985, Volume: 17, Issue:2

    Topics: Adrenal Medulla; Animals; Blood Pressure; Hypotension; Male; Prazosin; Pressoreceptors; Propranolol;

1985
Cerebrovascular responses to haemorrhagic hypotension in anaesthetized cats. Effects of alpha-adrenoceptor antagonists.
    Acta physiologica Scandinavica, 1985, Volume: 123, Issue:3

    Topics: Anesthesia, General; Animals; Blood Pressure; Cats; Cerebral Arteries; Cerebrovascular Circulation;

1985
Cardiovascular adrenoreceptor balance during hemorrhagic hypotension and shock.
    Circulatory shock, 1985, Volume: 16, Issue:2

    Topics: Animals; Cyclooxygenase Inhibitors; Hypotension; Male; Meclofenamic Acid; Prazosin; Rats; Rats, Inbr

1985