prazosin has been researched along with Hemorrhage in 18 studies
Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.
Hemorrhage: Bleeding or escape of blood from a vessel.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The role of alpha(1)-adrenergic stimulation in myocardial TNF-alpha expression and depressed cardiac function after HS/R was assessed by treatment with the alpha(1)-adrenergic inhibitor, prazosin hydrochloride (1 mg/kg ip), for 1 h before the onset of hemorrhage." | 3.71 | Hemorrhage-induced alpha-adrenergic signaling results in myocardial TNF-alpha expression and contractile dysfunction. ( Klein, LV; Lindsay, TF; Marshall, JG; Nicholson, S; Rubin, BB; Shahani, R; Walker, PM, 2001) |
| "5 mg/kg) or Group 3, captopril (4 mg/kg), each followed by bleeding as in the group 1." | 3.69 | Insight into blood-pressure control in SHR via the response to acute hemorrhage: a spectral analysis approach. ( Akselrod, S; Cohen, S; Eliash, S; Oz, O, 1995) |
| "To determine the importance of alpha 1-adrenergic receptors in the endocrine responses of fetal lambs to hemorrhage, eight chronically instrumented fetal lambs were bled of 20% of their measured blood volume after pretreatment with prazosin (24." | 3.67 | Endocrine responses of fetal lambs to hemorrhage after alpha 1-adrenergic receptor blockade. ( Barnes, KD; Block, SM; Rawashdeh, N; Ray, D; Rose, JC, 1988) |
| " Indomethacin treatment (5 mg/kg ia) of piglets following hemorrhage caused a significant decrease in blood flow to all brain regions within 20 min." | 3.67 | Adrenergic and prostanoid mechanisms in control of cerebral blood flow in hypotensive newborn pigs. ( Armstead, WM; Beasley, DG; Busija, DW; Leffler, CW; Mirro, R, 1988) |
| " Pretreatment with guanethidine did not affect basal output of HCO3- but markedly reduced the bleeding-induced response." | 3.67 | Bleeding-induced decrease in duodenal HCO3- secretion in the rat is mediated via alpha 2-adrenoceptors. ( Fändriks, L; Jönson, C, 1987) |
| "Hemorrhage was conducted over 5 min at the level of 0." | 1.29 | Effects of alpha-adrenergic activation on the shift of electrolytes and fluid after hemorrhage in rats. ( Nagashima, K, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (27.78) | 18.7374 |
| 1990's | 10 (55.56) | 18.2507 |
| 2000's | 3 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, Y | 1 |
| Liu, H | 1 |
| Gaskari, SA | 1 |
| Tyberg, JV | 1 |
| Lee, SS | 1 |
| Mathis, KW | 1 |
| Molina, PE | 1 |
| Nagashima, K | 1 |
| Almog, Y | 1 |
| Eliash, S | 3 |
| Oz, O | 3 |
| Akselrod, S | 3 |
| Cohen, S | 2 |
| Baujard, C | 1 |
| Ponchon, P | 3 |
| Elghozi, JL | 3 |
| Meldrum, DR | 2 |
| Cleveland, JC | 2 |
| Meng, X | 1 |
| Sheridan, BC | 2 |
| Banerjee, A | 2 |
| Harken, AH | 2 |
| Rowland, RT | 1 |
| Selzman, CH | 1 |
| Shahani, R | 1 |
| Klein, LV | 1 |
| Marshall, JG | 1 |
| Nicholson, S | 1 |
| Rubin, BB | 1 |
| Walker, PM | 1 |
| Lindsay, TF | 1 |
| Hasser, EM | 1 |
| Schadt, JC | 1 |
| Leffler, CW | 2 |
| Busija, DW | 2 |
| Share, L | 1 |
| Crofton, JT | 1 |
| Brooks, DP | 1 |
| Beasley, DG | 2 |
| Green, RS | 1 |
| Mirro, R | 2 |
| Block, SM | 1 |
| Rose, JC | 1 |
| Ray, D | 1 |
| Rawashdeh, N | 1 |
| Barnes, KD | 1 |
| Jordan, DA | 1 |
| Breslow, MJ | 1 |
| Kubos, KL | 1 |
| Traystman, RJ | 1 |
| Armstead, WM | 1 |
| Jönson, C | 1 |
| Fändriks, L | 1 |
18 other studies available for prazosin and Hemorrhage
| Article | Year |
|---|---|
Altered mesenteric venous capacitance and volume pooling in cirrhotic rats are mediated by nitric oxide.
Topics: Animals; Blood Volume; Hemorrhage; Liver Cirrhosis, Experimental; Mesenteric Veins; NG-Nitroarginine | 2008 |
Central acetylcholinesterase inhibition improves hemodynamic counterregulation to severe blood loss in alcohol-intoxicated rats.
Topics: Alcoholic Intoxication; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Bl | 2009 |
Effects of alpha-adrenergic activation on the shift of electrolytes and fluid after hemorrhage in rats.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Body Fluids; Electrolytes; Hemodynamics; Hemorrh | 1995 |
Nonlinear analysis of BP signal. Can it detect malfunctions in BP control?
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Hemorrhage; Models, Cardiovascular; Prazosin; | 1996 |
Insight into blood-pressure control in SHR via the response to acute hemorrhage: a spectral analysis approach.
Topics: Acute Disease; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Angiotensin-Co | 1995 |
Effects of graded hemorrhage on short-term variability of blood pressure in conscious rats.
Topics: Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Gas Analysis; Blood Pressure; Blood Prot | 1996 |
Effect of haemorrhage on the power of low frequency blood pressure fluctuations in young spontaneously hypertensive rats.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agon | 1995 |
Hemorrhage induces acute cardioadaptation to ischemia-reperfusion by an alpha1-adrenoceptor-mediated, protein synthesis-independent mechanism.
Topics: Adaptation, Physiological; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Coronary Circulati | 1997 |
Alpha-adrenergic activation of myocardial NF kappa B during hemorrhage.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cell Nucleus; Coronary Circulation; Cytoplasm | 1997 |
Contribution of humoral systems to the short-term variability of blood pressure after severe hemorrhage.
Topics: Animals; Antihypertensive Agents; Arginine Vasopressin; Biphenyl Compounds; Blood Pressure; Carbon D | 1997 |
Contribution of humoral systems to the recovery of blood pressure following severe haemorrhage.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Angiotensin II; Animals; Anti | 1997 |
Hemorrhage-induced alpha-adrenergic signaling results in myocardial TNF-alpha expression and contractile dysfunction.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Hemorrhage; Male; Myocardial Contr | 2001 |
Sympathoinhibition and its reversal by naloxone during hemorrhage.
Topics: Analysis of Variance; Animals; Blood Pressure; Heart Rate; Hemodynamics; Hemorrhage; Kidney; Male; N | 1992 |
Adrenergic mediation of vasopressin secretion in newborn pigs.
Topics: Animals; Animals, Newborn; Blood Pressure; Hemorrhage; Hydrogen-Ion Concentration; Lypressin; Prazos | 1987 |
Endocrine responses of fetal lambs to hemorrhage after alpha 1-adrenergic receptor blockade.
Topics: Adrenergic alpha-Antagonists; Animals; Endocrine Glands; Hemodynamics; Hemorrhage; Hydrocortisone; P | 1988 |
Adrenergic receptors of adrenal medullary vasculature.
Topics: Adrenal Medulla; Animals; Catecholamines; Dogs; Hemorrhage; Hypotension; Microspheres; Pindolol; Pra | 1989 |
Adrenergic and prostanoid mechanisms in control of cerebral blood flow in hypotensive newborn pigs.
Topics: Animals; Animals, Newborn; Blood Pressure; Brain; Carbon Dioxide; Cerebrovascular Circulation; Hemor | 1988 |
Bleeding-induced decrease in duodenal HCO3- secretion in the rat is mediated via alpha 2-adrenoceptors.
Topics: Animals; Bicarbonates; Duodenum; Guanethidine; Hemorrhage; Male; Prazosin; Propranolol; Rats; Rats, | 1987 |