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prazosin and Genetic Predisposition

prazosin has been researched along with Genetic Predisposition in 2 studies

Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.

Research Excerpts

ExcerptRelevanceReference
"Narcolepsy is a genetically determined disorder of sleep characterized by excessive daytime sleepiness and abnormal manifestations of REM sleep that affects both humans and animals."1.29Heterozygosity at the canarc-1 locus can confer susceptibility for narcolepsy: induction of cataplexy in heterozygous asymptomatic dogs after administration of a combination of drugs acting on monoaminergic and cholinergic systems. ( Arrigoni, J; Ciaranello, RD; Dement, WC; Edgar, DM; Mignot, E; Nishino, S; Reid, MS; Sharp, LH; Siegel, JM, 1993)
"Dogs with an inherited predisposition to sudden death display ventricular arrhythmias having certain characteristics, such as pause dependence, that are suggestive of early afterdepolarization-induced triggered activity."1.29Phenylephrine-induced ventricular arrhythmias in dogs with inherited sudden death. ( Brittain, D; Flahive, WJ; Gilmour, RF; Lee, RJ; Lewis, BA; Moïse, NS; Moon, PF; Pride, HP; Zipes, DP, 1996)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mignot, E1
Nishino, S1
Sharp, LH1
Arrigoni, J1
Siegel, JM1
Reid, MS1
Edgar, DM1
Ciaranello, RD1
Dement, WC1
Moïse, NS1
Moon, PF1
Flahive, WJ1
Brittain, D1
Pride, HP1
Lewis, BA1
Zipes, DP1
Lee, RJ1
Gilmour, RF1

Other Studies

2 other studies available for prazosin and Genetic Predisposition

ArticleYear
Heterozygosity at the canarc-1 locus can confer susceptibility for narcolepsy: induction of cataplexy in heterozygous asymptomatic dogs after administration of a combination of drugs acting on monoaminergic and cholinergic systems.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1993, Volume: 13, Issue:3

    Topics: Aging; Animals; Azepines; Biogenic Amines; Brain; Cataplexy; Chromosome Mapping; Crosses, Genetic; D

1993
Phenylephrine-induced ventricular arrhythmias in dogs with inherited sudden death.
    Journal of cardiovascular electrophysiology, 1996, Volume: 7, Issue:3

    Topics: Animals; Atropine; Cardiac Pacing, Artificial; Death, Sudden; Dogs; Female; Genetic Predisposition t

1996