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prazosin and Envenomation, Scorpion

prazosin has been researched along with Envenomation, Scorpion in 38 studies

Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.

Research Excerpts

ExcerptRelevanceReference
"We report the ameliorating effects of prazosin on the cardiovascular CV manifestations and pulmonary edema PE after treatment with antivenom AV failed to improve the conditions of scorpion stung patients."7.74Role of prazosin on cardiovascular manifestations and pulmonary edema following severe scorpion stings in Saudi Arabia. ( Abdulmaksood, NA; Al-Asmari, AK; Al-Seif, AA; Hassen, MA, 2008)
"The time taken in recovery from pulmonary edema was significantly shorter in cases treated with prazosin (28 +/- 18."5.14Management of scorpion sting: prazosin or dobutamine. ( Gupta, BD; Parakh, M; Purohit, A, 2010)
"We report the ameliorating effects of prazosin on the cardiovascular CV manifestations and pulmonary edema PE after treatment with antivenom AV failed to improve the conditions of scorpion stung patients."3.74Role of prazosin on cardiovascular manifestations and pulmonary edema following severe scorpion stings in Saudi Arabia. ( Abdulmaksood, NA; Al-Asmari, AK; Al-Seif, AA; Hassen, MA, 2008)
"The combination of nifedipine and prazosin was more successful in preventing myocardial damage in 16 patients with hypertension than was nifedipine alone in two other patients with hypertension."3.68Management of the cardiovascular manifestations of poisoning by the Indian red scorpion (Mesobuthus tamulus). ( Bawaskar, HS; Bawaskar, PH, 1992)
" Secondary end points were time required for complete resolution of clinical syndrome, prevention of deterioration to higher grade, doses of prazosin required overall and within 10 hours, and adverse events."2.76Efficacy and safety of scorpion antivenom plus prazosin compared with prazosin alone for venomous scorpion (Mesobuthus tamulus) sting: randomised open label clinical trial. ( Bawaskar, HS; Bawaskar, PH, 2011)
"The scorpion envenomation is considered the second event by poisonous animals in importance around the world according to the World Health Organization."1.38Cardiovascular dysfunction and pulmonary edema secondary to severe envenoming by Tityus pachyurus sting. Case report. ( Izquierdo, LM; Rodríguez Buitrago, JR, 2012)
"Prazosin is supposed to be a physiological & pharmalogical antidote of the scorpion venom but we studied efficacy of dobutamine in prazosin-resistant cardiotoxic cases."1.35A retrospective analysis of a rural set up experience with special reference to dobutamine in prazosin-resistant scorpion sting cases. ( Patil, SN, 2009)
"Eight children had pulmonary edema and hypotension; two had pulmonary edema and hypertension while one each presented with hypertension and tachycardia in isolation."1.32Clinical profile of severe scorpion envenomation in children at rural setting. ( Bawaskar, HS; Bawaskar, PH, 2003)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19902 (5.26)18.7374
1990's8 (21.05)18.2507
2000's14 (36.84)29.6817
2010's13 (34.21)24.3611
2020's1 (2.63)2.80

Authors

AuthorsStudies
Abdel Baseer, KA1
Aboelela, MG1
Qubaisy, HM1
Rodrigo, C1
Gnanathasan, A1
Del Brutto, OH1
Del Brutto, VJ1
Rathod, SG1
Tambat, SB1
Pandurang, KS1
Singh, J1
Bijesh, S1
Singh, HP1
Pandi, K1
Krishnamurthy, S2
Srinivasaraghavan, R2
Mahadevan, S3
Kumar, PM1
Harichandrakumar, KT1
D'sa, SR1
Peter, JV1
Chacko, B1
Pichamuthu, K1
Sathyendra, S1
Patil, SN1
Gupta, BD1
Parakh, M1
Purohit, A1
Peker, E1
Oktar, S1
Dogan, M1
Kaya, E1
Duru, M1
Prasad, R1
Mishra, OP1
Pandey, N1
Singh, TB1
Bawaskar, HS15
Bawaskar, PH14
Izquierdo, LM1
Rodríguez Buitrago, JR1
Kadhiravan, T1
Adhisivam, B1
Joshi, SR1
Sapatnekar, SM1
Al-Asmari, AK1
Al-Seif, AA1
Hassen, MA1
Abdulmaksood, NA1
Warrell, DA1
Murthy, KR1
Deshpande, SB1
Alex, AB1
Nanivadekar, A1
Kulkarni, AG1

Reviews

2 reviews available for prazosin and Envenomation, Scorpion

ArticleYear
Management of scorpion envenoming: a systematic review and meta-analysis of controlled clinical trials.
    Systematic reviews, 2017, 04-08, Volume: 6, Issue:1

    Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Antivenins; Controlled Clinical Trials as Topic; D

2017
Scorpion sting.
    Indian pediatrics, 2000, Volume: 37, Issue:5

    Topics: Adrenergic alpha-Antagonists; Animals; Antivenins; Child; Electrocardiography; Humans; Prazosin; Pul

2000

Trials

6 trials available for prazosin and Envenomation, Scorpion

ArticleYear
Efficacy of scorpion antivenom plus prazosin versus prazosin alone for Mesobuthus tamulus scorpion sting envenomation in children: a randomised controlled trial.
    Archives of disease in childhood, 2014, Volume: 99, Issue:6

    Topics: Administration, Intravenous; Adolescent; Adrenergic alpha-1 Receptor Antagonists; Animals; Antivenin

2014
Management of scorpion sting: prazosin or dobutamine.
    Journal of tropical pediatrics, 2010, Volume: 56, Issue:2

    Topics: Administration, Oral; Adrenergic alpha-Antagonists; Animals; Cardiotonic Agents; Child; Dobutamine;

2010
Scorpion sting envenomation in children: factors affecting the outcome.
    Indian journal of pediatrics, 2011, Volume: 78, Issue:5

    Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Child; Child, Preschool; Drug Administration Sched

2011
Efficacy and safety of scorpion antivenom plus prazosin compared with prazosin alone for venomous scorpion (Mesobuthus tamulus) sting: randomised open label clinical trial.
    BMJ (Clinical research ed.), 2011, Jan-05, Volume: 342

    Topics: Administration, Oral; Adolescent; Adrenergic alpha-1 Receptor Antagonists; Adult; Animals; Antivenin

2011
Utility of scorpion antivenin vs prazosin in the management of severe Mesobuthus tamulus (Indian red scorpion) envenoming at rural setting.
    The Journal of the Association of Physicians of India, 2007, Volume: 55

    Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Animals; Antivenins; Child; Child, Preschool; Femal

2007
Vasodilators: scorpion envenoming and the heart (an Indian experience).
    Toxicon : official journal of the International Society on Toxinology, 1994, Volume: 32, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Bradycardia; Cardiovascular Diseases; Child; Ch

1994

Other Studies

30 other studies available for prazosin and Envenomation, Scorpion

ArticleYear
Echocardiographic Evaluation of the Response to Prazosin Treatment in Scorpion Sting.
    Journal of tropical pediatrics, 2021, 07-02, Volume: 67, Issue:3

    Topics: Adolescent; Child; Echocardiography; Humans; Male; Prazosin; Prospective Studies; Scorpion Stings; V

2021
Scorpion stings: focus on cerebrovascular complications of envenoming.
    International journal of stroke : official journal of the International Stroke Society, 2013, Volume: 8, Issue:4

    Topics: Adult; Animals; Antivenins; Cerebrovascular Disorders; Clinical Trials as Topic; Combined Modality T

2013
Management of severe scorpion sting at a rural hospital.
    Indian pediatrics, 2013, Jun-08, Volume: 50, Issue:6

    Topics: Adolescent; Adrenergic alpha-1 Receptor Antagonists; Antivenins; Child; Child, Preschool; Female; Ho

2013
Effectiveness of anti scorpion venom for red scorpion envenomation.
    Indian pediatrics, 2014, Volume: 51, Issue:2

    Topics: Adrenergic beta-1 Receptor Agonists; Antivenins; Case-Control Studies; Child; Child, Preschool; Dobu

2014
Predictors of Myocardial Dysfunction in Children with Indian Red Scorpion (Mesobuthus tamulus) Sting Envenomation.
    Indian pediatrics, 2015, Volume: 52, Issue:4

    Topics: Antihypertensive Agents; Antivenins; Cardiomyopathies; Child, Preschool; Female; Humans; Immunologic

2015
Intra-aortic balloon pump (IABP) rescue therapy for refractory cardiogenic shock due to scorpion sting envenomation.
    Clinical toxicology (Philadelphia, Pa.), 2016, Volume: 54, Issue:2

    Topics: Activities of Daily Living; Adult; Animals; Antihypertensive Agents; Blood Pressure; Cardiotonic Age

2016
A retrospective analysis of a rural set up experience with special reference to dobutamine in prazosin-resistant scorpion sting cases.
    The Journal of the Association of Physicians of India, 2009, Volume: 57

    Topics: Adolescent; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adult; Aged; Animals; Antivenins

2009
Prazosin treatment in the management of scorpion envenomation.
    Human & experimental toxicology, 2010, Volume: 29, Issue:3

    Topics: Administration, Oral; Adrenergic Antagonists; Animals; Antidotes; Child, Preschool; Female; Humans;

2010
Cardiovascular dysfunction and pulmonary edema secondary to severe envenoming by Tityus pachyurus sting. Case report.
    Toxicon : official journal of the International Society on Toxinology, 2012, Sep-15, Volume: 60, Issue:4

    Topics: Animals; Antivenins; Child; Dopamine; Drug Therapy, Combination; Heart Arrest; Humans; Male; Nitropr

2012
Scorpion sting: update.
    The Journal of the Association of Physicians of India, 2012, Volume: 60

    Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Antivenins; Humans; Prazosin; Scorpion Stings; Sco

2012
Clinical profile of severe scorpion envenomation in children at rural setting.
    Indian pediatrics, 2003, Volume: 40, Issue:11

    Topics: Adolescent; Animals; Antivenins; Child; Child, Preschool; Combined Modality Therapy; Dobutamine; Fem

2003
Myocardial stunning due to sudden emotional stress.
    The New England journal of medicine, 2005, May-05, Volume: 352, Issue:18

    Topics: Adrenergic alpha-Antagonists; Animals; Catecholamines; Humans; Myocardial Stunning; Prazosin; Scorpi

2005
Of prazosin and purses.
    Lancet (London, England), 2006, Nov-25, Volume: 368, Issue:9550

    Topics: Adrenergic alpha-Antagonists; Animals; Child; Humans; Male; Prazosin; Scorpion Stings; Scorpions; Ti

2006
Stings and hopes: toxinomics and autonomic storm in the Indian red scorpion (Mesobuthus tamulus concanesis, Pocock).
    The Journal of the Association of Physicians of India, 2007, Volume: 55

    Topics: Adrenergic alpha-Antagonists; Animals; Antivenins; Humans; Prazosin; Scorpion Stings; Scorpion Venom

2007
Role of prazosin on cardiovascular manifestations and pulmonary edema following severe scorpion stings in Saudi Arabia.
    Saudi medical journal, 2008, Volume: 29, Issue:2

    Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adult; Animals; Antivenins; Child, Preschool; Fe

2008
Severe envenoming by the Indian red scorpion Mesobuthus tamulus: the use of prazosin therapy.
    QJM : monthly journal of the Association of Physicians, 1996, Volume: 89, Issue:9

    Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Aged; Animals; Cardiac Output, Low; Child; Child, P

1996
Prazosin: scorpion envenoming and the cardiovascular system.
    Tropical doctor, 1997, Volume: 27, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Cardiovascular Diseases; Humans; Ind

1997
Scorpion envenoming and the cardiovascular system.
    Tropical doctor, 1997, Volume: 27, Issue:1

    Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Animals; Antihypertensive Agents; Cardiovascular Di

1997
Management of scorpion sting.
    Heart (British Cardiac Society), 1999, Volume: 82, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Hemodynamics; Humans; Prazosin; Scorpion Stings; Scorpions

1999
Scorpion sting.
    The Journal of the Association of Physicians of India, 1999, Volume: 47, Issue:8

    Topics: Animals; Humans; Multiple Organ Failure; Prazosin; Scorpion Stings; Scorpions; Treatment Outcome

1999
On the management of scorpion stings.
    Heart (British Cardiac Society), 2000, Volume: 83, Issue:5

    Topics: Algorithms; Animals; Antihypertensive Agents; Aprotinin; Captopril; Humans; Prazosin; Respiratory In

2000
Prazosin therapy and scorpion envenomation.
    The Journal of the Association of Physicians of India, 2000, Volume: 48, Issue:12

    Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Animals; Child; Child, Preschool; Female; Humans; I

2000
Endothelin, nitric oxide and prazosin.
    The Journal of the Association of Physicians of India, 2000, Volume: 48, Issue:12

    Topics: Adrenergic alpha-Antagonists; Animals; Endothelin-1; Humans; Nitric Oxide; Phosphodiesterase Inhibit

2000
Call for global snake-bite control and procurement funding.
    Lancet (London, England), 2001, Apr-07, Volume: 357, Issue:9262

    Topics: Animals; Antivenins; Humans; India; Prazosin; Scorpion Stings; Scorpion Venoms; Scorpions; Snake Bit

2001
Researcher, clinician, or teacher?
    Lancet (London, England), 2001, Sep-15, Volume: 358, Issue:9285

    Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Humans; Hypertension; India; Prazosi

2001
Prazosin therapy and scorpion envenomation.
    The Journal of the Association of Physicians of India, 2001, Volume: 49

    Topics: Adrenergic alpha-Antagonists; Animals; Humans; Prazosin; Scorpion Stings; Scorpions

2001
Management of the cardiovascular manifestations of poisoning by the Indian red scorpion (Mesobuthus tamulus).
    British heart journal, 1992, Volume: 68, Issue:5

    Topics: Adult; Aged; Animals; Cardiovascular Diseases; Child; Child, Preschool; Drug Therapy, Combination; F

1992
Treatment of cardiovascular manifestations of human scorpion envenoming: is serotherapy essential?
    The Journal of tropical medicine and hygiene, 1991, Volume: 94, Issue:3

    Topics: Animals; Antivenins; Cardiovascular Diseases; Humans; India; Nifedipine; Prazosin; Scorpion Stings;

1991
Prazosin in management of cardiovascular manifestations of scorpion sting.
    Lancet (London, England), 1986, Mar-01, Volume: 1, Issue:8479

    Topics: Adolescent; Adult; Animals; Cardiovascular Diseases; Child; Child, Preschool; Humans; Middle Aged; P

1986
Prazosin for vasodilator treatment of acute pulmonary oedema due to scorpion sting.
    Annals of tropical medicine and parasitology, 1987, Volume: 81, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Animals; Child; Child, Preschool; Electrocardiography; Female; Hum

1987